Proceedings of IEEE Sensors, 2004.最新文献_第9页

A new architecture for TOF-based range-finding sensor 基于tof的新型测距传感器结构

Proceedings of IEEE Sensors, 2004. Pub Date : 2004-01-01 DOI: 10.1109/ICSENS.2004.1426205

D. Stoppa, L. Viarani, A. Simoni, L. Gonzo, M. Malfatti

引用次数: 4

Signal enhancement of protein arrays using particles 利用粒子增强蛋白质阵列的信号

Proceedings of IEEE Sensors, 2004. Pub Date : 2004-01-01 DOI: 10.1109/ICSENS.2004.1426292

C. Preininger, U. Sauer

{"title":"Signal enhancement of protein arrays using particles","authors":"C. Preininger, U. Sauer","doi":"10.1109/ICSENS.2004.1426292","DOIUrl":"https://doi.org/10.1109/ICSENS.2004.1426292","url":null,"abstract":"Microarrays are a widely used bioanalytical tool in diagnostics, drug discovery and life science research. However, most microarrays suffer from insufficient sensitivity at low probe and target concentration and from a sometimes poor signal-to-noise ratio. This problem can be overcome by the development of 3-dimensional surfaces that provide increased immobilization capacities, by applying more sensitive detection techniques (e.g. evanescent wave technology, surface enhanced fluorescence techniques) or by using alternative labels (e.g. metal particles, quantum dots) that show a brighter luminescence and are more photostable. In our strategies for signal enhancement of protein arrays, we focus on particle arrays and Au-particles as alternative labels. Microparticles coated with IgG (immunoglobulin G) or streptavidin-IgG were arrayed in a print buffer, e.g. PBS or betaine, or a hydrogel, e.g. poly(vinyl alcohol) or pluronic polymers, on to various chip surfaces providing multiple assay replicates. 5, 10, and 40 nm Au-particles were used as labels in antibody arrays. When processing the array with fluorophor (Dy633) and Au labelled targets in different ratios, surface enhanced fluorescence was observed. The enhanced fluorescence was not only a result of the particles' size and the ratio and distance of the Dy633 and Au particles, but also the density of reactive surface groups and thus the density of bound IgG. When comparing both approaches to usual planar arrays, far higher signal-to-noise ratios could be achieved.","PeriodicalId":20476,"journal":{"name":"Proceedings of IEEE Sensors, 2004.","volume":"PP 1","pages":"808-809 vol.2"},"PeriodicalIF":0.0,"publicationDate":"2004-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84363249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Non-contact 2D speckle vibrometer 非接触式二维散斑振动计

Proceedings of IEEE Sensors, 2004. Pub Date : 2004-01-01 DOI: 10.1109/ICSENS.2004.1426485

L. Scalise, A. di Donato

引用次数: 0

Development and applications of the distributed temperature and strain sensors based on Brillouin scattering 基于布里渊散射的分布式温度应变传感器的研制与应用

Proceedings of IEEE Sensors, 2004. Pub Date : 2004-01-01 DOI: 10.1109/ICSENS.2004.1426396

X. Bao, Lufan Zou, Qinrong Yu, Liang Chen

引用次数: 20

Surface modifications of AlGaN/GaN sensors for water based nano- and picodroplets [chemical and biosensors] 用于水基纳米液滴和微液滴的AlGaN/GaN传感器的表面改性[化学和生物传感器]

Proceedings of IEEE Sensors, 2004. Pub Date : 2004-01-01 DOI: 10.1109/ICSENS.2004.1426343

C. Buchheim, V. Lebedev, V. Yanev, G. Kittler, M. Fischer, G. Ecke, O. Ambacher, V. Cimalla, S. Krischok, J. Schaefer

引用次数: 3

Rapid investigation of nanocrystalline diamond vibrating membranes with a stroboscopic interferometer 用频闪干涉仪快速研究纳米晶金刚石振动膜

Proceedings of IEEE Sensors, 2004. Pub Date : 2004-01-01 DOI: 10.1109/ICSENS.2004.1426121

L. Francis, A. Kromka, D. Steinmuller-Nethl, P. Bertrand, C. van Hoof

引用次数: 2

High temperature optical fiber oxygen probe 高温光纤氧探头

Proceedings of IEEE Sensors, 2004. Pub Date : 2004-01-01 DOI: 10.1109/ICSENS.2004.1426385

R. Ghosh, D. Osborn, G. Baker

引用次数: 0

Ultrasonic piezoceramic transducer modeling with VHDL-AMS IEEE 1076.1 基于VHDL-AMS IEEE 1076.1的超声压电换能器建模

Proceedings of IEEE Sensors, 2004. Pub Date : 2004-01-01 DOI: 10.1109/ICSENS.2004.1426106

R. Guelaz, D. Kourtiche, M. Nadi, Y. Hervé

引用次数: 10

DNA detection by self-assembled nano-particle and integrated photodiodes 自组装纳米粒子与集成光电二极管的DNA检测

Proceedings of IEEE Sensors, 2004. Pub Date : 2004-01-01 DOI: 10.1109/ICSENS.2004.1426355

Jiong Li, Chen Xu, Zhikuan Zhang, Yijin Wang, H. Peng, Zuhong Lu, M. Chan

引用次数: 0

Gas sensing using carbon nanotube-based resonator 基于碳纳米管谐振器的气体传感

Proceedings of IEEE Sensors, 2004. Pub Date : 2004-01-01 DOI: 10.1109/ICSENS.2004.1426183

S. Chopra, S. Natarajan, A. Rao

引用次数: 9