Polish journal of veterinary sciences最新文献_第9页

Comparative evaluation of different techniques for herniorrhaphy in calves. 小腿疝修补术不同技术的比较评价。

IF 0.8 4区农林科学

Polish journal of veterinary sciences Pub Date : 2022-06-01 DOI: 10.24425/pjvs.2022.141804

A Fatima, M Arif Khan, S Aslam, K Ashraf, A Khalid Mahmood, M Asif, S Shah, N Hussain

{"title":"Comparative evaluation of different techniques for herniorrhaphy in calves.","authors":"A Fatima, M Arif Khan, S Aslam, K Ashraf, A Khalid Mahmood, M Asif, S Shah, N Hussain","doi":"10.24425/pjvs.2022.141804","DOIUrl":"https://doi.org/10.24425/pjvs.2022.141804","url":null,"abstract":"Umbilical hernia is one of the most common problems in young calves. This problem occurs in dairy sector as well as in the local farmers. Present study was conducted to compare outcomes of four different techniques of herniorrhaphy. Twenty four young calves (n=24) were divided in 4 groups (A, B, C, and D) which underwent four different surgical techniques. Group A underwent vicryl plus suture material and pants-over-west technique, Group B underwent mesh application with Dexon suture material by using simple interrupted suture pattern, Group C underwent closed method with Nylon No. 3 suture material by using vertical mattress suture pattern and Group D underwent clamp application method with Silk No. 2 suture material by using simple interrupted suture pattern. The result showed that mesh application method was comparatively better with respect to feed intake, body weight gain and healing time. There was no reoccurrence with non-significant hematological changes (p≤0.05). It is concluded that mesh application method is safer than other three techniques and there are no systemic effects of this surgical intervention on calves' health.","PeriodicalId":20366,"journal":{"name":"Polish journal of veterinary sciences","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40613347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

A novel orchiectomy surgical procedure in donkeys ( Equus asinus africanus) with parascrotal access. 一种新的睾丸切除手术方法在驴(马asinus africanus)与副下丘脑通路。

IF 0.8 4区农林科学

Polish journal of veterinary sciences Pub Date : 2022-06-01 DOI: 10.24425/pjvs.2022.141814

R A Barrêto, L A Rodrigues, J P Albuquerque, F J A de Sousa, P R Firmino, R S Sousa, V J Pedrosa, T R do Amaral, A H H Minervino

{"title":"A novel orchiectomy surgical procedure in donkeys ( Equus asinus africanus) with parascrotal access.","authors":"R A Barrêto, L A Rodrigues, J P Albuquerque, F J A de Sousa, P R Firmino, R S Sousa, V J Pedrosa, T R do Amaral, A H H Minervino","doi":"10.24425/pjvs.2022.141814","DOIUrl":"https://doi.org/10.24425/pjvs.2022.141814","url":null,"abstract":"Donkeys are a public health concern in the Northeast region of Brazil, with thousands of stray animals. Orchiectomy is an important population control measure; however, the long postoperative period with daily treatment of open wounds in the scrotum makes it difficult to perform a large number of castrations in sheltering centers. We evaluate a novel surgical procedure for orchiectomy in donkeys using parascrotal access. Twelve donkeys were used, divided into two groups: I - submitted to orchiectomy through parascrotal surgical access (novel procedure), and II - submitted to orchiectomy through scrotal access (conventional). Postoperative evaluations consisted of a macroscopic evaluation of the surgical wound (bleeding and intensity of edema), hematological parameters, and peritoneal fluid, which occurred in both groups at the moments (M): M0 - before the surgical procedure. The others moments occurred after surgery: M12 (twelve hours); M24 (twenty-four hours); M48 (forty-eight hours); M72 (seventy-two hours); M8D (eight days); and M16D (sixteen days). The surgical techniques did not generate an important systemic inflammatory response to the point detected by the leukogram, fibrinogen dosage, and peritoneal fluid. The parascrotal technique required long surgery but promoted less bleeding, less edema, and faster healing. The techniques used did not promote sufficient systemic inflammation to alter the number of leukocytes and the fibrinogen concentration; however, evaluation of the peritoneal fluid proved to be important for evaluating inflammatory processes involving the scrotum and inguinal canal. We describe a novel surgical procedure for orchiectomy in Donkeys using a parascrotal access that promoted less risk of bleeding, shorter period of edema, and healing time, but required longer surgery time.","PeriodicalId":20366,"journal":{"name":"Polish journal of veterinary sciences","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40634818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparison of the effectiveness of selected essential oils with mineral oil and spinosad on Dermanyssus gallinae. 精选精油与矿物油、皂苷对鸡皮蛾的药效比较。

IF 0.8 4区农林科学

Polish journal of veterinary sciences Pub Date : 2022-06-01 DOI: 10.24425/pjvs.2022.141810

M Roczeń-Karczmarz, M Demkowska-Kutrzepa, J Zdybel, K Szczepaniak, M Studzińska, K Tomczuk

{"title":"Comparison of the effectiveness of selected essential oils with mineral oil and spinosad on Dermanyssus gallinae.","authors":"M Roczeń-Karczmarz, M Demkowska-Kutrzepa, J Zdybel, K Szczepaniak, M Studzińska, K Tomczuk","doi":"10.24425/pjvs.2022.141810","DOIUrl":"https://doi.org/10.24425/pjvs.2022.141810","url":null,"abstract":"It seems that essential oils can be a good ingredient in effective preparations against Dermanyssus gallinae. Dermanyssus affects animal health leading to financial losses and bird welfare issues. Collected mites were treated with various essential oils in four (20, 50, 80 and 100%) concentrations at a dose of 0.28 mg/cm2. The direct toxicity of the essential oils, mineral oil and spinosad to D. gallinae was tested in the laboratory. Eucalyptus oil was the most toxic essential oil in all concentrations to D. gallinae (87.6 - 97.6% mortality at all four concentrations), while geranium, pine and rosemary oils showed mortality rates of 14.2 - 68.2%. High mortality after 48 hours of contact was also recorded for the oil of cloves at 80% dilution (85.1% mortality), lavender 100% (94.2% mortality). Similarly, the thyme essential oil produced 83.5 - 93.2% mortality in three concentrations: 50, 80 and 100%. The mineral oil was the least effective oil against mites. Spinosad showed high effectiveness against D. gallinae.","PeriodicalId":20366,"journal":{"name":"Polish journal of veterinary sciences","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40634821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Determination of the embryotoxic effect of maropitant using an in ovo model. 用卵内模型测定马洛匹坦的胚胎毒性作用。

IF 0.8 4区农林科学

Polish journal of veterinary sciences Pub Date : 2022-06-01 DOI: 10.24425/pjvs.2022.141821

M Uslu, R Canbar, G Akcakavak, E Yazar

引用次数: 1

Integrated basic lung and heart ultrasound with X-ray (TUSX) for the diagnosis of asthma, chronic bronchitis and laryngeal paralysis, and treatment with inhaled fluticasone using home-made mask in dogs and cats. 综合基础肺脏超声与x线(TUSX)诊断哮喘、慢性支气管炎和喉麻痹，并使用自制口罩吸入氟替卡松治疗犬猫。

IF 0.8 4区农林科学

Polish journal of veterinary sciences Pub Date : 2022-06-01 DOI: 10.24425/pjvs.2022.141819

A Łobaczewski, M Czopowicz, A Moroz, M Mickiewicz, A Kosiec-Tworus, T Frymus, O Szaluś-Jordanow

{"title":"Integrated basic lung and heart ultrasound with X-ray (TUSX) for the diagnosis of asthma, chronic bronchitis and laryngeal paralysis, and treatment with inhaled fluticasone using home-made mask in dogs and cats.","authors":"A Łobaczewski, M Czopowicz, A Moroz, M Mickiewicz, A Kosiec-Tworus, T Frymus, O Szaluś-Jordanow","doi":"10.24425/pjvs.2022.141819","DOIUrl":"https://doi.org/10.24425/pjvs.2022.141819","url":null,"abstract":"Basic lung and heart ultrasound examination combined with chest X-ray (TUSX) is currently considered to be very useful for differentiation of asthma, chronic bronchitis and laryngeal paralysis from other diseases with dyspnea/coughing. Among 252 client-owned animals with persistent dyspnea/cough/noisy breathing, in 197 of them: pulmonary edema, pneumonia, lung cancer, free pleural fluid, pneumothorax, lung contusion or heart disease were diagnosed. The remaining 55 animals (42 dogs and 13 cats) were diagnosed with asthma (in 13 cats), chronic bronchitis (in 37 dogs) and laryngeal paralysis (in 5 dogs) using TUSX. These animals were qualified for inhaled fluticasone treatment using 3 types of spacers - two commercial and a home- -made mask. 36 animals (65.5%) completed the trail. In 26 of them (72.2%) the owners observed complete, long lasting relief of the symptoms, and the owners of 7 animals (19.5%) declared a considerable clinical improvement, regardless of the type of spacer used. The owners of 3 animals (8.3%) did not see any improvement. The proposed diagnostic and therapeutic management improved long-term clinical status of the vast majority (91.7%) of animals. Therefore, it seems justified to include the TUSX diagnostic protocol in daily veterinary practice and to encourage owners to prepare home-made face masks for inhaled fluticasone treatment.","PeriodicalId":20366,"journal":{"name":"Polish journal of veterinary sciences","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40526714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Measurement of the physicochemical, performance, and consumer-information characteristics of commercial nonmedicated shampoo for dogs. 商用狗用非药物洗发水的理化、性能和消费者信息特征的测量。

IF 0.8 4区农林科学

Polish journal of veterinary sciences Pub Date : 2022-06-01 DOI: 10.24425/pjvs.2022.141805

S I Peña-Corona, I Juárez-Rodríguez, D Vargas-Estrada, E Amador-González, L Arvizu-Tovar, O Soberanis-Ramos

{"title":"Measurement of the physicochemical, performance, and consumer-information characteristics of commercial nonmedicated shampoo for dogs.","authors":"S I Peña-Corona, I Juárez-Rodríguez, D Vargas-Estrada, E Amador-González, L Arvizu-Tovar, O Soberanis-Ramos","doi":"10.24425/pjvs.2022.141805","DOIUrl":"https://doi.org/10.24425/pjvs.2022.141805","url":null,"abstract":"The aim was to analyze the quality of commercial shampoo without prophylactic effect for dogs. The analysis was based on the evaluations and requirements established for human-line products since there is no guide for veterinary products in Mexico; such evaluations have not been carried out or published in Mexico. Physicochemical, sensory, performance, and consumer information tests of the shampoo were carried out. The sample consisted of twenty products marketed in Mexico City. During the evaluation of the label, a serious non-compliance with applicable regulations was found. The pH of the products ranged between 5.6 and 8.4; Significant differences (p⟨0.05) were found between the three groups with low (6.1), medium (7.2), and high (8.1) pH. Viscosity values were from 1131 to 3102. For the foam index, no statistically significant differences were found. 100% of the products analyzed complied with the rest of the quality tests carried out. The results of the quality analysis in this study will allow veterinarians specializing in small species to better select and recommend the products for their use and inform dog owners, about the safety, and value of the products.","PeriodicalId":20366,"journal":{"name":"Polish journal of veterinary sciences","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40613348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Efficacy of Lamiaceae essential oils with selected azoles against Candida albicans clinical isolates. 兰科精油与选定的唑类抗白色念珠菌临床分离株的疗效研究。

IF 0.8 4区农林科学

Polish journal of veterinary sciences Pub Date : 2022-06-01 DOI: 10.24425/pjvs.2022.141812

M Proškovcová, E Čonková, P Váczi, D Marcinčáková, M Harčárová

{"title":"Efficacy of Lamiaceae essential oils with selected azoles against Candida albicans clinical isolates.","authors":"M Proškovcová, E Čonková, P Váczi, D Marcinčáková, M Harčárová","doi":"10.24425/pjvs.2022.141812","DOIUrl":"https://doi.org/10.24425/pjvs.2022.141812","url":null,"abstract":"A current problem in candidiasis treatment is increasing resistance to azoles, which are often prescribed to patients. The study underlines the high resistance of yeasts to fluconazole, which achieved high MIC (minimal inhibitory concentration) values both alone and in combination with essential oils (EOs). Antifungal activity of Hyssopus officinalis, Thymus vulgaris, Salvia officinalis and Rosmarinus officinalis EOs was determined against 13 clinical isolates of Candida albicans and reference strain Candida albicans ATCC 10231. The synergistic effect was investigated for the combination of itraconazole and fluconazole with Hyssopus officinalis and Thymus vulgaris EOs. Based on the fractional inhibitory concentration index, the synergistic effect was achieved in all of the samples exposed to itraconazole with Hyssopus officinalis (FICI 0.3±0.06). On the other side, the additive effect was proven in use of itraconazole with Thymus vulgaris (FICI 0.75±0.35) and fluconazole with both EOs tested (FICI 0.81±0.19; 0.88±0.57) This study shows the importance of monitoring the synergistic effect of antifungals combined with EOs, because it is a possible solution for reducing the resistance and improving the disease prognosis.","PeriodicalId":20366,"journal":{"name":"Polish journal of veterinary sciences","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40613349","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Identification of bacterial species in milk by MALDI-TOF and assessment of some oxidant-antioxidant parameters in blood and milk from cows with different health status of the udder. MALDI-TOF法鉴定牛奶中细菌种类及不同乳房健康状况奶牛血液和牛奶中一些氧化-抗氧化参数的评价

IF 0.8 4区农林科学

Polish journal of veterinary sciences Pub Date : 2022-06-01 DOI: 10.24425/pjvs.2022.141811

G Ozbey, Z Cambay, S Yilmaz, O Aytekin, F Zigo, M Ozçelik, B Otlu

{"title":"Identification of bacterial species in milk by MALDI-TOF and assessment of some oxidant-antioxidant parameters in blood and milk from cows with different health status of the udder.","authors":"G Ozbey, Z Cambay, S Yilmaz, O Aytekin, F Zigo, M Ozçelik, B Otlu","doi":"10.24425/pjvs.2022.141811","DOIUrl":"https://doi.org/10.24425/pjvs.2022.141811","url":null,"abstract":"This study aimed to identify bacterial pathogens in milk samples from dairy cows with subclinical and clinical mastitis as well as to assess the concentrations of oxidant-antioxidant parameters [malondialdehyde (MDA), reduced glutathione (GSH), and total GSH levels] in both blood and milk samples. From a total of 200 dairy cows in 8 farms, 800 quarter milk samples obtained from each udder were tested in the laboratory for the presence of udder pathogens. Cultivated bacteria causing intramammary infection from milk samples were identified by Matrix-Assisted Laser Desorption/Ionization-Time of Flight (MALDI-TOF). In addition, from tested animals 60 cows were selected includıng 20 healthy cows that were CMT negative, 20 cows with subclinical mastitis (SM), and 20 cows with clinical mastitis (CM) for detection of MDA, GSH, and total GSH levels in blood and milk samples. Three hundred and eighty (47.5%; 380/800), 300 (37.5%; 300/800), and 120 (15%; 120/800) of milk samples, respectively were CMT positive or SM and CM, and those positives were cows from different farms. We observed that 87.4% (332/380), 25.3% (76/300), and 34.2% (41/120) of cows with CMT positive, CMT negative, and CM had bacterial growth. The most predominantly identified bacteria were Staphylococcus chromogenes (18.7%) obtained mainly from SM and Staphylococcus aureus (16.7%) as the most frequent cause of CM. According to our results, dairy cows with CM had the highest MDA levels, the lowest GSH, and total GSH levels in both blood and milk samples however, high MDA levels and low GSH levels in milk samples with SM were observed. Based on our results, lipid oxidant MDA and antioxidant GSH could be excellent biomarkers of cow's milk for developing inflammation of the mammary gland. In addition, there was no link between nutrition and MDA and GSH levels.","PeriodicalId":20366,"journal":{"name":"Polish journal of veterinary sciences","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40634816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Immunoreactivity of acetylcholinesterase and M1 muscarinic receptors in the hippocampus and striatum of rats treated with Rebaudioside A. 雷鲍迪甙A对大鼠海马和纹状体乙酰胆碱酯酶和M1毒蕈碱受体免疫反应性的影响。

IF 0.8 4区农林科学

Polish journal of veterinary sciences Pub Date : 2022-06-01 DOI: 10.24425/pjvs.2022.141815

K Rycerz, J Jaworska-Adamu, A Krawczyk, M B Arciszewski

{"title":"Immunoreactivity of acetylcholinesterase and M1 muscarinic receptors in the hippocampus and striatum of rats treated with Rebaudioside A.","authors":"K Rycerz, J Jaworska-Adamu, A Krawczyk, M B Arciszewski","doi":"10.24425/pjvs.2022.141815","DOIUrl":"https://doi.org/10.24425/pjvs.2022.141815","url":null,"abstract":"Rebaudioside A (RebA) is a steviol glycoside used for production of sweeteners. It was shown that the glycosides affect memory and learning processes. The aim of the study was to investigate neurons immunoreactive for acetylcholinesterase (AChE) and M1 muscarinic receptors (mAChRs-M1) of the hippocampal CA1 and CA3 fields and striatal caudateputamen (CP) and globus pallidus (GP) in rats receiving RebA. RebA was administrated to adult rats for 45 days in dilutions of 1 mg and 2 mg RebA/ml water. Indirect peroxidase-antiperoxidase immunohistochemical reaction was conducted on frontal sections containing the hippocampus and striatum with use of antibodies against AChE and mAChRs-M1. Immunoreactive for the studied proteins neurons were morphologically and morphometrically assessed in hippocampal CA1 and CA3 fields and in CP and GP. Microscopic observations did not reveal significant changes in morphology of immunoreactive neurons, which suggests no neurotoxic effect of the studied glycoside on these cells. Morphometric analyses revealed an increase in the density of AChE and mAChRs-M1 immunoreactive neurons. A decrease in reaction intensity of AChE-positive neurons was also demonstrated in the hippocampal CA1 field and in GP. In contrast, an increase in reaction intensity of mAChRs-M1-positive neurons was found in CA1, CA3 fields and in CP and GP. The results of our preliminary studies indicate that RebA administrated to rats has an impact on cholinergic neurons in the studied area. The results suggest a possible increase in the activity of the cholinergic system, responsible for memory and learning processes, after administration of RebA.","PeriodicalId":20366,"journal":{"name":"Polish journal of veterinary sciences","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40634819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Plasma interleukin-1α and interleukin-8 in female dogs with non-metastatic and metastatic malignant mammary gland tumours. 雌性犬非转移性和转移性恶性乳腺肿瘤患者血浆白细胞介素-1α和白细胞介素-8的研究。

IF 0.8 4区农林科学

Polish journal of veterinary sciences Pub Date : 2022-06-01 DOI: 10.24425/pjvs.2022.141817

M Szczubiał, W Łopuszyński, R Dąbrowski, M Bochniarz, P Brodzki

{"title":"Plasma interleukin-1α and interleukin-8 in female dogs with non-metastatic and metastatic malignant mammary gland tumours.","authors":"M Szczubiał, W Łopuszyński, R Dąbrowski, M Bochniarz, P Brodzki","doi":"10.24425/pjvs.2022.141817","DOIUrl":"https://doi.org/10.24425/pjvs.2022.141817","url":null,"abstract":"In this study plasma concentrations of IL-1α and IL-8 in 29 female dogs with malignant mammary gland tumours (19 without metastasis and 10 with metastasis) and in 10 healthy control animals were determined. Concentrations of IL-1α and IL-8 were analysed using a specific canine ELISA assay. Mean plasma concentrations of IL-1α and IL-8 were significantly higher (p⟨0.05) in female dogs with both non-metastatic and metastatic malignant tumours compared to the healthy animals. The concentrations of both tested cytokines were significantly increased (p⟨0.05) in the dogs with metastasis. In female dogs with mammary carcinomas, the plasma concentration of IL-1α was significantly higher (p⟨0.05) in the animals with grade 3 tumours compared to the dogs with grade 1 tumours. The concentration of IL-8 was significantly higher (p⟨0.05) in the dogs with grade 3 tumours compared to that found in the animals with grade 1 and grade 2 tumours. A moderate correlation (r=0.433) was found between IL-1α and IL-8 concentrations in the female dogs. These findings suggest that increased malignancy and invasiveness of canine mammary tumours is associated with an increased production of IL-1α and IL-8 in the tumour microenvironment, which, in turn, leads to an increase in their circulating levels. This may indicate that circulating levels of the cytokines investigated could be considered as diagnostic and prognostic markers in canine malignant mammary tumours. However, further studies in this fields are needed.","PeriodicalId":20366,"journal":{"name":"Polish journal of veterinary sciences","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40526712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1