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2013 Transducers & Eurosensors XXVII: The 17th International Conference on Solid-State Sensors, Actuators and Microsystems (TRANSDUCERS & EUROSENSORS XXVII)最新文献

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The influence of molecular charges on microtubule curvatures in an electrical field 电场中分子电荷对微管曲率的影响
2013 Transducers & Eurosensors XXVII: The 17th International Conference on Solid-State Sensors, Actuators and Microsystems (TRANSDUCERS & EUROSENSORS XXVII) Pub Date : 2013-10-10 DOI: 10.1109/TRANSDUCERS.2013.6627221
N. Isozaki, T. Nakahara, S. Ando, N. K. Kamisetty, H. Shintaku, H. Kotera, E. Meyhofer, R. Yokokawa
{"title":"The influence of molecular charges on microtubule curvatures in an electrical field","authors":"N. Isozaki, T. Nakahara, S. Ando, N. K. Kamisetty, H. Shintaku, H. Kotera, E. Meyhofer, R. Yokokawa","doi":"10.1109/TRANSDUCERS.2013.6627221","DOIUrl":"https://doi.org/10.1109/TRANSDUCERS.2013.6627221","url":null,"abstract":"Toward a novel molecular separation, we propose a method to control gliding directions of microtubules (MTs) using a kinesin-MT system. The directions are controlled by electrical charges of cargo molecules partially labeled on the minus ends of MTs. We designed MTs labeled with streptavidin (SA), nanogold (NG), or dsDNA molecules, and evaluated their curvatures in an electrical field. The curvature of DNA-MT was larger than those of SA-MT or NG-MT because of DNA's large negative charge. These differences of curvatures enable to separate gliding MTs according to their cargo molecules.","PeriodicalId":202479,"journal":{"name":"2013 Transducers & Eurosensors XXVII: The 17th International Conference on Solid-State Sensors, Actuators and Microsystems (TRANSDUCERS & EUROSENSORS XXVII)","volume":"68 1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130031127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Droplet bisulfite conversion platform for epigenetic cancer biomarker detection 亚硫酸氢盐液滴转化平台用于表观遗传癌症生物标志物检测
2013 Transducers & Eurosensors XXVII: The 17th International Conference on Solid-State Sensors, Actuators and Microsystems (TRANSDUCERS & EUROSENSORS XXVII) Pub Date : 2013-10-10 DOI: 10.1109/TRANSDUCERS.2013.6627235
D. J. Shin, A. Stark, T. H. Wang
{"title":"Droplet bisulfite conversion platform for epigenetic cancer biomarker detection","authors":"D. J. Shin, A. Stark, T. H. Wang","doi":"10.1109/TRANSDUCERS.2013.6627235","DOIUrl":"https://doi.org/10.1109/TRANSDUCERS.2013.6627235","url":null,"abstract":"We report an integrated digital microfluidic platform for methylation biological samples. Recent advances in epigenetic studies highlight the importance of DNA methylation in the biology of cancer. The epigenetic signature of promoter regions in the genes ADAMTS1 and BNC1 has been shown to have strong correlation with the early stages of pancreatic carcinogenesis [1]. Most analytical techniques for studying methylation require pre-processing of sample DNA via bisulfite conversion. However, repetitive addition and removal of liquid reagents using conventional tubes and pipettes present a technical hurdle for microliter-scale reagents, as well as a high risk for contamination and human error. Previously, we reported a magnetically actuated platform for integrated DNA extraction and amplification from crude biological samples [2]. In this work, we demonstrate a self-contained, magnetically-actuated droplet cartridge for bisulfite treatment of genomic DNA with enhanced performance compared to the tube-based process.","PeriodicalId":202479,"journal":{"name":"2013 Transducers & Eurosensors XXVII: The 17th International Conference on Solid-State Sensors, Actuators and Microsystems (TRANSDUCERS & EUROSENSORS XXVII)","volume":"28 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129032448","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Combination of temperature cycled and gate bias cycled operation to enhance the selectivity of SiC-FET gas sensors 结合温度循环和栅极偏置循环工作，提高SiC-FET气体传感器的选择性
2013 Transducers & Eurosensors XXVII: The 17th International Conference on Solid-State Sensors, Actuators and Microsystems (TRANSDUCERS & EUROSENSORS XXVII) Pub Date : 2013-10-10 DOI: 10.1109/TRANSDUCERS.2013.6627199
C. Bur, M. Bastuck, A. Schutze, A. Lloyd Spetz, M. Andersson
{"title":"Combination of temperature cycled and gate bias cycled operation to enhance the selectivity of SiC-FET gas sensors","authors":"C. Bur, M. Bastuck, A. Schutze, A. Lloyd Spetz, M. Andersson","doi":"10.1109/TRANSDUCERS.2013.6627199","DOIUrl":"https://doi.org/10.1109/TRANSDUCERS.2013.6627199","url":null,"abstract":"In this paper temperature modulation and gate bias modulation of a gas sensitive field effect transistor are combined in order to increase the selectivity. Data evaluation was performed using multivariate statistics, here by Linear Discriminant Analysis. It was found that both temperature cycling and gate bias cycling are suitable for quantification of different concentrations of carbon monoxide. However, combination of both approaches enhances the quality of the separation. In addition, the presented method allows discrimination of carbon monoxide, nitrogen dioxide and ammonia independent of the gas concentration.","PeriodicalId":202479,"journal":{"name":"2013 Transducers & Eurosensors XXVII: The 17th International Conference on Solid-State Sensors, Actuators and Microsystems (TRANSDUCERS & EUROSENSORS XXVII)","volume":"39 3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130788223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Microsystems and functional assays for mechanobiology 机械生物学的微系统和功能分析
2013 Transducers & Eurosensors XXVII: The 17th International Conference on Solid-State Sensors, Actuators and Microsystems (TRANSDUCERS & EUROSENSORS XXVII) Pub Date : 2013-10-10 DOI: 10.1109/TRANSDUCERS.2013.6627369
B. Pruitt, J. Doll, S. Park, N. Harjee, B. Petzold
{"title":"Microsystems and functional assays for mechanobiology","authors":"B. Pruitt, J. Doll, S. Park, N. Harjee, B. Petzold","doi":"10.1109/TRANSDUCERS.2013.6627369","DOIUrl":"https://doi.org/10.1109/TRANSDUCERS.2013.6627369","url":null,"abstract":"Microsystems and cantilever-based assays enable a wealth of custom measurements and analysis systems matched to the scale of cell biomechanics and mechanotransduction assays. Novel force and displacement sensors and actuators have been applied to study mechanisms of cell adhesion and the development and response of pluripotent cells in varied mechanical environments, to assay the function of hear cells, and to probe the mechanics and biology of the sense of touch in C. elegans or the mechanosensation of hair cells. In the Stanford Microsystems Lab, we design and fabricate many custom tools and sensors to probe cellular dynamics. We are interested in the reliable manufacture and operation of these micromachined devices in harsh biological environments as well as calibration approaches for precise measurements of nanoscale mechanical behaviors. We use these tools to address questions in the areas of physiology, biology, stem cells, neuroscience and cardiology with an eye toward quantitative and fundamental biophysics. In particular, microcantilevers have enabled measurements in a variety of applications over the past decades, ranging from scanning probe microscopy to visualize topography or characterize materials properties, to chemical sensing. Piezoresistive cantilever sensing offers particular advantages for system integration, scaling, and simplicity of transduction.","PeriodicalId":202479,"journal":{"name":"2013 Transducers & Eurosensors XXVII: The 17th International Conference on Solid-State Sensors, Actuators and Microsystems (TRANSDUCERS & EUROSENSORS XXVII)","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127183963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Autonomous microfluidic control by mixed potentials generated on composite metal electrodes 复合金属电极上产生混合电位的自主微流控
2013 Transducers & Eurosensors XXVII: The 17th International Conference on Solid-State Sensors, Actuators and Microsystems (TRANSDUCERS & EUROSENSORS XXVII) Pub Date : 2013-10-10 DOI: 10.1109/TRANSDUCERS.2013.6626786
K. Kojima, M. Yokokawa, H. Suzuki
{"title":"Autonomous microfluidic control by mixed potentials generated on composite metal electrodes","authors":"K. Kojima, M. Yokokawa, H. Suzuki","doi":"10.1109/TRANSDUCERS.2013.6626786","DOIUrl":"https://doi.org/10.1109/TRANSDUCERS.2013.6626786","url":null,"abstract":"A new concept and devices for autonomous switching of valves and pumps in microfabricated flow channels are proposed. An electrowetting-based valve consisting of gold and zinc opened when an electrolyte solution reached the zinc part in a controlling flow channel and a mixed potential was applied to the gold valve electrode. Clock circuits that open the valves at predetermined times and logic circuits have been realized. A bubble micropump that moves a solution forward and backward was also constructed with three flow channels in which platinum black, zinc, and silver electrodes connected with each other. The technique was also used to create a device that ejects a solution in response to the concentration of creatinine and urea.","PeriodicalId":202479,"journal":{"name":"2013 Transducers & Eurosensors XXVII: The 17th International Conference on Solid-State Sensors, Actuators and Microsystems (TRANSDUCERS & EUROSENSORS XXVII)","volume":"56 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114819923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A microfluidic system with volume sensor and dielectric glucose sensor for continuous glucose monitoring 一种具有体积传感器和介质葡萄糖传感器的微流体系统，用于连续血糖监测
2013 Transducers & Eurosensors XXVII: The 17th International Conference on Solid-State Sensors, Actuators and Microsystems (TRANSDUCERS & EUROSENSORS XXVII) Pub Date : 2013-10-10 DOI: 10.1109/TRANSDUCERS.2013.6626778
D. Li, H. Yu, X. Huang, B. Song, Y. Jia, Y. Ji, N. Li, J. Chen, K. Xu, Q. Lin
{"title":"A microfluidic system with volume sensor and dielectric glucose sensor for continuous glucose monitoring","authors":"D. Li, H. Yu, X. Huang, B. Song, Y. Jia, Y. Ji, N. Li, J. Chen, K. Xu, Q. Lin","doi":"10.1109/TRANSDUCERS.2013.6626778","DOIUrl":"https://doi.org/10.1109/TRANSDUCERS.2013.6626778","url":null,"abstract":"We present a microfluidic system for interstitial fluid (ISF) transdermal extraction, ISF volume measurement, and dielectric glucose sensing towards the application of continuous glucose monitoring. This device significantly incorporates a MEMS volume sensor, which measures extracted ISF volume via conductance monitoring, and integrates a MEMS dielectric glucose sensor, which specifically measures glucose concentrations in the transdermally extracted ISF via affinity binding. The volume sensor and the glucose sensor in the microfluidic system are characterized. The feasibility of the single-chip device for automated, accurate, and continuous monitoring of subcutaneous ISF glucose concentrations is verified.","PeriodicalId":202479,"journal":{"name":"2013 Transducers & Eurosensors XXVII: The 17th International Conference on Solid-State Sensors, Actuators and Microsystems (TRANSDUCERS & EUROSENSORS XXVII)","volume":"14 3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123589709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
In vitro tumor model for evaluating the lung cancer induced tumor angiogenesis 评价肺癌诱导肿瘤血管生成的体外肿瘤模型
2013 Transducers & Eurosensors XXVII: The 17th International Conference on Solid-State Sensors, Actuators and Microsystems (TRANSDUCERS & EUROSENSORS XXVII) Pub Date : 2013-10-10 DOI: 10.1109/TRANSDUCERS.2013.6627002
Tse-shao Chen, Kuo-Wei Chang, S. Sivashankar, Kang-Yun Lee, Cheng-Hsien Liu
{"title":"In vitro tumor model for evaluating the lung cancer induced tumor angiogenesis","authors":"Tse-shao Chen, Kuo-Wei Chang, S. Sivashankar, Kang-Yun Lee, Cheng-Hsien Liu","doi":"10.1109/TRANSDUCERS.2013.6627002","DOIUrl":"https://doi.org/10.1109/TRANSDUCERS.2013.6627002","url":null,"abstract":"Angiogenesis is not only physiological changes necessary for some process, but also some scientists have found it plays a role in development of cancer. When the tumor is newly formed, the cancer cell itself or the surrounding connective tissue secretes many proteins to promote angiogenesis. These substances will activate endothelial cells, for example: (a) decomposition of the tumor surrounding connective tissue damage; (b) endothelial cell proliferation; (c) the place of endothelial cells to promote the secretion of angiogenic substance transportation; (d) endothelial cells is reassembled into new blood vessels. We try to mimic the phenomenon of the angiogenic by chip.","PeriodicalId":202479,"journal":{"name":"2013 Transducers & Eurosensors XXVII: The 17th International Conference on Solid-State Sensors, Actuators and Microsystems (TRANSDUCERS & EUROSENSORS XXVII)","volume":"99 ","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131549997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Functionalized carbon nanotubes for the discrimination of volatile organic compounds 功能化碳纳米管在挥发性有机物鉴别中的应用
2013 Transducers & Eurosensors XXVII: The 17th International Conference on Solid-State Sensors, Actuators and Microsystems (TRANSDUCERS & EUROSENSORS XXVII) Pub Date : 2013-10-10 DOI: 10.1109/TRANSDUCERS.2013.6626963
I. Hafaiedh, W. El Euch, P. Clément, A. Abdelghani, E. Llobet
{"title":"Functionalized carbon nanotubes for the discrimination of volatile organic compounds","authors":"I. Hafaiedh, W. El Euch, P. Clément, A. Abdelghani, E. Llobet","doi":"10.1109/TRANSDUCERS.2013.6626963","DOIUrl":"https://doi.org/10.1109/TRANSDUCERS.2013.6626963","url":null,"abstract":"Oxygen plasma functionalized and decorated with iron oxide nanoparticle multiwall carbon nanotubes (MWCNTs) are used for detecting volatile organic compounds at room temperature. Sensors as the ones presented here, which can respond to aromatic VOCs and fully recover their baseline at room temperature, pave the way for a new generation of affordable, mass produced portable/ wearable detectors with important applications in continuous environmental monitoring or workplace protection.","PeriodicalId":202479,"journal":{"name":"2013 Transducers & Eurosensors XXVII: The 17th International Conference on Solid-State Sensors, Actuators and Microsystems (TRANSDUCERS & EUROSENSORS XXVII)","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130266946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Improvement of hot switching lifetime in MEMS DC switches using a drain voltage-sustaining capacitor 利用漏极电压维持电容改善MEMS直流开关的热开关寿命
2013 Transducers & Eurosensors XXVII: The 17th International Conference on Solid-State Sensors, Actuators and Microsystems (TRANSDUCERS & EUROSENSORS XXVII) Pub Date : 2013-10-10 DOI: 10.1109/TRANSDUCERS.2013.6626824
Yong-Ha Song, Min-Woo Kim, Sangsoo Ahn, Jun‐Bo Yoon
{"title":"Improvement of hot switching lifetime in MEMS DC switches using a drain voltage-sustaining capacitor","authors":"Yong-Ha Song, Min-Woo Kim, Sangsoo Ahn, Jun‐Bo Yoon","doi":"10.1109/TRANSDUCERS.2013.6626824","DOIUrl":"https://doi.org/10.1109/TRANSDUCERS.2013.6626824","url":null,"abstract":"Reliability in hot switching operations of MEMS DC switches is enhanced by introducing a drain voltage-sustaining capacitor, which leads to electric field-less or arc-less switching operations. The role of the capacitor is to eliminate the electric potential difference between the suspended beam and the drain electrode at the switch “opening” instant. In the case of a pure Au-Au contact, we have experimentally demonstrated that the lifetime of conventional MEMS switches with the suggested method was improved dramatically, by an order of magnitude, in the relatively high electric-field hot switching condition. We clearly observed material transfer at failure in the device without the capacitor, whereas stiction was the main failure mechanism in the device with the capacitor. Owing to the simplicity of the proposed method, it can be adopted in any type of MEMS DC switches in order to greatly enhance the switch lifetime.","PeriodicalId":202479,"journal":{"name":"2013 Transducers & Eurosensors XXVII: The 17th International Conference on Solid-State Sensors, Actuators and Microsystems (TRANSDUCERS & EUROSENSORS XXVII)","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124249854","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Multidimensional metamaterial fluid sensor 多维超材料流体传感器
2013 Transducers & Eurosensors XXVII: The 17th International Conference on Solid-State Sensors, Actuators and Microsystems (TRANSDUCERS & EUROSENSORS XXVII) Pub Date : 2013-10-10 DOI: 10.1109/TRANSDUCERS.2013.6627123
R. Lucklum, M. Zubtsov, A. Oseev, A. Omar, A. Martínez
{"title":"Multidimensional metamaterial fluid sensor","authors":"R. Lucklum, M. Zubtsov, A. Oseev, A. Omar, A. Martínez","doi":"10.1109/TRANSDUCERS.2013.6627123","DOIUrl":"https://doi.org/10.1109/TRANSDUCERS.2013.6627123","url":null,"abstract":"We report for the first time on a fluid sensor platform applying simultaneously confined electromagnetic and acoustic waves. Confinement is realized in a so-called phoxonic crystal, a specific version of a metamaterial. Metamaterials are engineered to achieve desired effects by incorporating structural elements of (sub-)wavelength sizes. The sensor platform is a solid plate featuring an array of holes arranged in a square lattice. A defect introduces local resonances and the resonance frequency has been found to depend on refractive index or permittivity and mass attached to the defect.","PeriodicalId":202479,"journal":{"name":"2013 Transducers & Eurosensors XXVII: The 17th International Conference on Solid-State Sensors, Actuators and Microsystems (TRANSDUCERS & EUROSENSORS XXVII)","volume":"40 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129900208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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