Banjai Mochahary, Sushil Kumar Middha, Talambedu Usha, None B. N. Nagalaxmi, Arvind Kumar Goyal
{"title":"Evaluating hepatoprotective activity of polyherbal formulations- an overview of dietary antioxidants","authors":"Banjai Mochahary, Sushil Kumar Middha, Talambedu Usha, None B. N. Nagalaxmi, Arvind Kumar Goyal","doi":"10.14719/pst.2556","DOIUrl":"https://doi.org/10.14719/pst.2556","url":null,"abstract":"Chronic liver disease is the foremost cause of morbidity, accounting for 2.2 percent of death. In recent years, excessive attention has been focused on using natural antioxidants as they have the potential to minimize oxidative stress in cells and thus help treat various ailments. Some scientists estimate that two-thirds of plant species have medical applications, and many of these have significant antioxidant potential. Polyherbal formulations (PHFs) have shown therapeutic promise in the treatment of several acute and chronic conditions, including diabetes, wound care, hypertension, cardiovascular disorders, anxiety, neurological imbalances, and disorders of the gastrointestinal, respiratory, and endocrine systems. This article reviews the antioxidant potential of the various polyherbal formulations developed to treat hepatic disorders during the past ten years. After preliminary screening, 53 abstracts based on the polyherbal formulations selected for hepatoprotection were retrieved from several bibliographical databases. This review provides insight and indicates the gaps presented in the case of polyherbal formulations (PHFs) formulations. To conclude, PHFs can activate several physiological processes that quicken the process. Clinical trials should be conducted to further examine these PHFs, and production upscaling will help to open up new markets for PHFs.","PeriodicalId":20236,"journal":{"name":"Plant Science Today","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135408321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Helichrysum kraussii Sch.Bip.: Review on its medicinal uses, phytochemistry and pharmacological properties","authors":"Alfred Maroyi","doi":"10.14719/pst.2402","DOIUrl":"https://doi.org/10.14719/pst.2402","url":null,"abstract":"Helichrysum kraussii Sch.Bip. is a woody shrub that naturally occurs in grasslands and woodlands in South-Central Africa. The various parts of H. kraussii serve as components used in traditional medicines within the South Central Africa region. This review provides an overview of the existing literature on the medicinal uses, phytochemical composition, and pharmacological properties of H. kraussii. The study reveals that various parts of the plant, including branches, flowers, leaves, roots, seeds, twigs, and whole plant parts, are used in ritual practices and traditional medicine to treat a range of human ailments. These include venereal diseases, nasal congestion, chest pain, skin infections, tuberculosis, respiratory infections, and cough. Phytochemical analysis of H. kraussii demonstrates the presence of acylated flavonol glucoside, diterpenes, flavonoids, phloroglucinol, and terpenoids. The pharmacological assessments indicate that crude extracts and isolated phytochemical compounds from this species possess antioxidant, antibacterial, antifungal, antiviral, cytotoxic, and anti-inflammatory activities. This mini review underscores the traditional uses, phytochemical composition, and pharmacological properties of H. kraussii. Based on the findings, it is recommended to conduct comprehensive ethnopharmacological evaluations of H. kraussii, focusing on phytochemistry, pharmacological properties, toxicological assessments, as well as in vivo and clinical research.","PeriodicalId":20236,"journal":{"name":"Plant Science Today","volume":"34 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135409016","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Evaluation of antidiabetic potential of Syzygium kanarense (Talbot) Raizada in streptozotocin- nicotinamide induced diabetic rats.","authors":"Sushmitha C H, Krishnakumar G","doi":"10.14719/pst.2680","DOIUrl":"https://doi.org/10.14719/pst.2680","url":null,"abstract":"Worldwide diabetes is the major killer disease and the antidiabetic drugs which are in use cause many side effects. Traditionally, some of the Syzygium spp. are in use for treating diabetes, and many species are being assessed for their antidiabetic property. This study is to assess the antidiabetic effectiveness of the bark of Syzygium kanarense (Talbot) Raizada. The antidiabetic efficacy of methanol and water extracts of the leaf (SKLM, SKLW) and the bark (SKBM, SKBW) were evaluated in vitro by the alpha-glucosidase- and alpha-amylase-inhibitory assays. The in vivo antidiabetic activity of the bark was assessed by oral glucose tolerance test (OGTT) and streptozotocin- nicotinamide (STZ-NA)-induced non-obese type 2 diabetic rat model. The serum biochemical parameters and histopathology of the pancreas, liver and kidney were evaluated after 21 days of treatment. The total phenolics and flavonoids were quantified in all the extracts. The antioxidant activity was assessed using the DPPH assay. Administration of SKBM and SKBW to STZ-NA-induced diabetic rats at 300 mg/kg and 600 mg/kg orally for 21 days exhibited statistically significant (P < 0.001) and dose-related drop in blood sugar levels, serum lipid and hepatorenal parameters. The extract-treated rats showed rejuvenated islets and increased beta-cell density in the pancreas, improved liver architecture and glomerular regeneration without fat deposition. Bark extracts showed the strongest alpha –glucosidase- and alpha –amylase-inhibitory activity in contrast to the leaf extracts. Antioxidants, phytoconstituents and antidiabetic action, as well as protection against free radical damage, were proved to be significantly correlated.","PeriodicalId":20236,"journal":{"name":"Plant Science Today","volume":"172 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135406819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Syafiqah Alia Sazali, Noraziyah Abd Aziz Shamsudin, Mohd Y. Rafii, Mohd Shahril Firdaus Ab Razak, Muhammad Fahmi Yunus, Fatien Najwa Che Yah, Firdaus Ahmad, None MOHD SYAHMI SALLEH
{"title":"Genetics, Physiological Mechanism and Breeding for Tolerance against Submergence, Salinity, and Saline-Submergence Stress in Rice (Oryza sativa L.)","authors":"Syafiqah Alia Sazali, Noraziyah Abd Aziz Shamsudin, Mohd Y. Rafii, Mohd Shahril Firdaus Ab Razak, Muhammad Fahmi Yunus, Fatien Najwa Che Yah, Firdaus Ahmad, None MOHD SYAHMI SALLEH","doi":"10.14719/pst.2536","DOIUrl":"https://doi.org/10.14719/pst.2536","url":null,"abstract":"Rice is a staple food and one of the most crucial crops globally, providing sustenance for more than half of the world's population. Climate change has a crucial impact on the agricultural sector, particularly rice cultivation, due to the increase in abiotic stress incidences. Salinity is one of the most severe abiotic stresses on rice production globally. Salt stress significantly reduces growth performance, affecting various metabolic and physiological processes in rice. Submergence is another type of abiotic stress affecting rice growth and yield. Recently, a newly emerged abiotic stress called saline submergence may also jeopardize rice production. Seawater intrusion into rice fields located nearby coastal areas may cause saline flash floods, especially during monsoon season. Rice cultivated in coastal areas is prone to saline-submergence stress, leading to a significantly lower yield. Although Sub1 and Saltol QTLs are widely used in developing rice cultivars with submergence and salinity tolerance, there is a lack of studies conducted to explore the potential performance of breeding lines with Sub1 and Saltol QTLs under saline-submergence stress. It has been hypothesized that the introgression of Sub1 and Saltol QTLs into elite rice cultivars might result in potentially tolerant breeding lines to saline-submergence stress. Further breeding projects, however, need to be conducted to prove this postulation. The present mini-review deals with genetics, physiological mechanisms, and breeding achievements for submergence and salinity-tolerant rice while at the same time highlighting saline-submergence as an emerging type of abiotic stress in rice cultivation.","PeriodicalId":20236,"journal":{"name":"Plant Science Today","volume":"42 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135539165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Traditional uses, phytochemistry and therapeutic efficacy of Cassava (Manihot esculenta Crantz) - A Review","authors":"None Barsha Sarma, None Tapashi Sutradhar, None Kakali Deka, None Mridul Kr. Borthakur","doi":"10.14719/pst.2406","DOIUrl":"https://doi.org/10.14719/pst.2406","url":null,"abstract":"The usage of naturally available resources by humans for gratifying different requirements is an age-old custom. This is because natural products provide indispensable facilities in the form of nutritional, economic, social, medicinal aspects and many more. Cassava (Manihot esculenta Crantz) has been used as an herbal medicine by different groups of ethnic people. Besides having medicinal prospect, this plant is commonly used as a source of nutrition for humans and animals in tropical regions. However, conduction of more studies to see if there is chemical, microbiological, and/or clinical evidence, from a scientific perspective, of their effectiveness for those ailments. Therefore, this review was conducted to summarize the traditional uses, to understand the phytochemistry and identify the possible correlation between bioactive compounds and corresponding pharmacological properties. A systematic and detailed literature search has been undertaken for the study by using standard search engines like Google Scholar, PubMed, SciFinder, Research Gate and Science Direct. The evidential information was then assembled to present the manuscript with separate sections. From the literature search, it came into focus that Cassava contains various secondary metabolites which exhibits some notable pharmacological activities like antioxidant, antiradical, anticancer, antibacterial, antifungal, antidiarrheal, analgesic and pesticidal activity. The biological activities established by cassava provide insight into its usagthe e in traditional medicinal systems. But an intricate and thorough review appears to be deficient on M. esculenta. Therefore, this review has summarized the studies investigating about the traditional uses, phytochemistry, bioactive compounds and therapeutic efficacy of M. esculenta. The significance of this review is aimed at a better understanding of the novel applications and further considerations for more logical and scientific evaluation. We hope this study will further aid in the development of research on this area to identify a new generation of natural source-based treatments that will help meet the growing consumer demand for safe, sustainable, and natural treatments.","PeriodicalId":20236,"journal":{"name":"Plant Science Today","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135961139","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
None Hamza Elbouny, None Ayoub Amssayef, None Chakib Alem
{"title":"Rosmarinic acid as a potential anti-hyperlipidemic agent","authors":"None Hamza Elbouny, None Ayoub Amssayef, None Chakib Alem","doi":"10.14719/pst.2362","DOIUrl":"https://doi.org/10.14719/pst.2362","url":null,"abstract":"Rosmarinic acid (RA) is a natural phytochemical that occurs in numerous plants, including Rosmarinus officinalis. This bioactive compound is widely reported to exert various pharmacological effects, including anti-hyperlipidemic activity. In this study, we reviewed the literature data on RA and hyperlipidemia research. In silico, in vitro, and in vivo studies were retrieved from Scholar, PubMed, ScienceDirect, Web of Science, and Scopus. The In silico studies revealed that RA possesses squalene synthase and 3-hydroxy-3-methylglutaryl–coenzyme A reductase enzymes inhibiting effect. Additionally, in vitro reports revealed that RA exerts remarkable lipid-lowering effects and also exhibits anti-adipogenic and anti-atherosclerotic activities. The lipid-lowering action was modulated by numerous mechanisms including the regulation of anti-inflammatory and antioxidant signaling pathways. Moreover, in vivo studies revealed that RA alleviates hyperlipidemia in animal models by modulating the expression of genes involved in hyperlipidemia as well as the regulation of gut microbiota and anti-inflammatory pathways. We conclude that RA is a multi-target anti-hyperlipidemic agent. Moreover, we suggest that the use of this bioactive compound as an anti-hyperlipidemic drug would be an effective pharmacological strategy that could provide promising options for the treatment and prevention of hyperlipidemia and its related disorders including atherosclerosis.","PeriodicalId":20236,"journal":{"name":"Plant Science Today","volume":"155 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135063249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Essential oil of Citrus hystrix DC.: A mini-review on chemical composition, extraction method, bioactivities, and potential applications in food and pharmaceuticals","authors":"None Le Pham Tan Quoc, None Do Minh Long","doi":"10.14719/pst.2508","DOIUrl":"https://doi.org/10.14719/pst.2508","url":null,"abstract":"Citrus hystrix DC. is a common herb in tropical regions. Its essential oils are now widely researched and applied because of their high economic value and safety for humans and are interesting materials for future trends. This review provides an extensive overview of the biological activities of C. hystrix essential oil, characterized predominantly by citronellal, ?-Pinene, sabinene, limonene, and terpinene-4-ol, which are deciding factors in antimicrobial, antioxidant, insect repellent, anti-tumor, and anti-inflammatory properties. Therefore, it is applied in the fields of food preservation and pharmaceuticals. However, these applications should consider the ratio of these components in the essential oil, which is variable when using materials from different parts of the plant and depending on the original location of the plant, growth stages, traditional or modern extraction methods, and pre-treatment methods.","PeriodicalId":20236,"journal":{"name":"Plant Science Today","volume":"64 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135063256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Review on the role of indigenous plants and plant derivatives of Ayurveda in bone healing","authors":"Poona Nath Chouhan, Abdulahat Azimov, Dilfuza Jabborova, Sachidanand Singh","doi":"10.14719/pst.2566","DOIUrl":"https://doi.org/10.14719/pst.2566","url":null,"abstract":"Ayurveda is an ancient medical science, that fundamentally manages the various disease by using plants and their derivatives. Bone healing is a complex process that needs restoration anatomically and physiologically. Ayurveda holds a rich knowledge of plant and their derivatives which possess certain bioactive compounds which act differently. Due to severe side effects by using synthetically derived compounds which have adverse effects like gastrointestinal bleeding, delayed blood clotting, and treatment lengthening, the use of synthetic compounds and minerals with NSAID on fractured bones also leads to low compliance among patients, alternate medicine is much needed. Earlier due to a lack of scientific studies and standardization of compounds, acceptance was not as per mark for the traditional system of medicine. However, with the rise in traditional practices their usage is also rising along with their reporting of their clinical efficacy creating a new hope to the world however due to lack of scientific support, they are not widely accepted. The article aims to review the available data to support the evaluation of plants described in Ayurveda. Textual literature, online resources, and electronic media are used to collect data. The review concluded that yet more research work has to be carried out with a modern approach to validate with more clarity.","PeriodicalId":20236,"journal":{"name":"Plant Science Today","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135152931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The effect of phytohormones on the flowering of plants","authors":"None Linh Minh Hong Tran","doi":"10.14719/pst.2558","DOIUrl":"https://doi.org/10.14719/pst.2558","url":null,"abstract":"During the development of angiosperms, one of the most critical stages of plants is the transition from vegetative to reproductive stage, and successfully producing seeds is necessary. Plants have developed a complex signaling pathway to recognize and combine endogenous and environmental signals. Plant growth regulators (PGRs) play a role in regulating flower growth on shoots. Physiological and biochemical processes work together to differentiate and produce flower buds. The impact of PGRs on floral bud differentiation has been the subject of several publications in recent years. In addition, the dynamic variations in gibberellin (GA), auxin, and cytokinin levels in buds and the hormonal-related signatures in gene regulatory networks indicate a crucial function for these hormones during floral bud development in plants. Especially the flowering hormone GA has a key role in regulating the activities related to flowering genes as well as controlling the activity of the DELLA protein. Abscisic acid (ABA) and ethylene (ET) have an inhibitory role in flowering but in some cases stimulate flowering depending on environmental conditions. This study aims to understand the regulation of phytohormones on flowering of plants and its effects on plant development during the flowering stage.","PeriodicalId":20236,"journal":{"name":"Plant Science Today","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135152922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
None Steffanny Sanchez-Portillo, Margarita del Rosario Salazar Sánchez, Jose Fernando Solanilla-Duque, Raúl Rodríguez Herrera
{"title":"Andean Tubers, Morphological Diversity, and Agronomic Management: A Review","authors":"None Steffanny Sanchez-Portillo, Margarita del Rosario Salazar Sánchez, Jose Fernando Solanilla-Duque, Raúl Rodríguez Herrera","doi":"10.14719/pst.2504","DOIUrl":"https://doi.org/10.14719/pst.2504","url":null,"abstract":"Andean tubers refer to a variety of roots and underground stems cultivated in the Andean region, which spans a significant portion of South America. Among these tubers are Arracacia xanthorrhiza, Tropaeolum tuberosum, Oxalis tuberosa, and Ullucus tuberosus. These tubers exhibit resistance to pests, extreme environmental conditions such as drought or frost, and various soil types. It also displays morphological diversity in terms of shape, color, and size, as well as nutritional variation depending on the specific variety grown and the type of propagation employed. While some agronomic requirements are similar for these tubers, others differ due to factors such as crop management, fertilization techniques, plant characteristics, and other influences that contribute to species-level variations. Therefore, it is important to understand the optimal cultivation conditions for achieving high production yields, comprehending the range of tuber variability, and exploring potential applications for these Andean tubers. It is worth noting that there is a lack of up-to-date information on this subject, highlighting the need for further research and exploration. Efforts have been made to classify and differentiate each tuber based on specific physical characteristics, utilizing reported taxonomic data. This classification system assists producers in distinguishing between the various tuber species and their respective varieties.","PeriodicalId":20236,"journal":{"name":"Plant Science Today","volume":"28 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135831131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}