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Chapter 6. Screening Technologies 第六章。筛选技术
Drug Repurposing Pub Date : 1900-01-01 DOI: 10.1039/9781839163401-00101
F. Sheinerman
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引用次数: 0
Chapter 1. Introduction and Historical Overview of Drug Repurposing Opportunities 第1章。药物再利用机会的介绍和历史概述
Drug Repurposing Pub Date : 1900-01-01 DOI: 10.1039/9781839163401-00001
S. Pushpakom
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引用次数: 3
Chapter 8. Using Artificial Intelligence for Drug Repurposing 第八章。使用人工智能进行药物再利用
Drug Repurposing Pub Date : 1900-01-01 DOI: 10.1039/9781839163401-00147
A. Bender
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引用次数: 0
Chapter 12. Adapting Payers’ and Producers’ Incentives to Drug Repurposing 第十二章。调整支付方和生产者对药物再利用的激励
Drug Repurposing Pub Date : 1900-01-01 DOI: 10.1039/9781839163401-00244
A. Cole, B. Handelin, D. Cavalla
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引用次数: 0
Chapter 15. Future Perspectives in Drug Repurposing 第15章。药物再利用的未来展望
Drug Repurposing Pub Date : 1900-01-01 DOI: 10.1039/9781839163401-00301
D. Cavalla
{"title":"Chapter 15. Future Perspectives in Drug Repurposing","authors":"D. Cavalla","doi":"10.1039/9781839163401-00301","DOIUrl":"https://doi.org/10.1039/9781839163401-00301","url":null,"abstract":"Drug repurposing offers a more efficient route to medicinal innovation than conventional new molecular entity research, and proposals for repurposing projects can come from in silico algorithms, pharmacological experimentation, clinical serendipity or retrospective analysis of human data. These approaches offer a much larger number of hypotheses for validation than can be resourced, and rigorous multidisciplinary prioritisation is required. The recent COVID-19 pandemic has highlighted the potential for the approach, which has produced three clinically effective treatments in under a year, including two regulatory approvals for emergency use, and one drug with demonstrated efficacy against mortality. Challenges remain in how to provide additional commercial incentives for drug companies to support late-stage development of repurposing projects and fully realise its healthcare potential. © The Royal Society of Chemistry 2022.","PeriodicalId":202024,"journal":{"name":"Drug Repurposing","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129836158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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