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[Long-term health-related quality of life of patients after prolonged weaning depending on weaning status]. [长期断奶后患者与健康相关的长期生活质量取决于断奶状态]。
IF 1.2
Pneumologie Pub Date : 2024-08-05 DOI: 10.1055/a-2368-4865
Bernd Schönhofer, Andrea Paul, Stefan Suchi, Maximilian Zimmermann, Sarah Bettina Stanzel, Wolfram Windisch, Melanie Berger
{"title":"[Long-term health-related quality of life of patients after prolonged weaning depending on weaning status].","authors":"Bernd Schönhofer, Andrea Paul, Stefan Suchi, Maximilian Zimmermann, Sarah Bettina Stanzel, Wolfram Windisch, Melanie Berger","doi":"10.1055/a-2368-4865","DOIUrl":"https://doi.org/10.1055/a-2368-4865","url":null,"abstract":"<p><strong>Introduction: </strong>Long-term outcome in patients with prolonged weaning is known to be impaired, particularly against the background of their weaning status; however, data on their health-related quality of life (HRQL) are sparse.</p><p><strong>Methods: </strong>HRQL was measured in patients with prolonged weaning using the Severe Respiratory Insufficiency Questionnaire (SRI).</p><p><strong>Results: </strong>Overall, 39 out of 83 patients with prolonged weaning filled in the SRI questionnaire. The median interval between discharge from hospital and HRQL assessment was 3.5 years (IQR 2.4-4.5 years). In the total group, the median SRI summary score was 56.4 (IQR 38.8-73.5). Patients with unsuccessful weaning and subsequent invasive home mechanical ventilation (N=15) had worse HRQL as estimated from the SRI summary score when compared to those with successful weaning both without (n=13) and with subsequent long-term non-invasive ventilation (NIV) (n=11); Kruskal-Wallis-Test: H (2, n=39) = 7,875446; P=0.0195. Statistically significant differences indicating worse HRQL in patients with invasive home mechanical ventilation were particularly evident in the following SRI subscales: Social relationships (P=0.0325), Anxiety (P=0.0096), and Psychological well-being (P=0.0079).</p><p><strong>Conclusions: </strong>HRQL is substantially impaired in patients with unsuccessful prolonged weaning and subsequent invasive home mechanical ventilation compared to those with successful prolonged weaning. Further studies incorporating higher case numbers are needed to assess other conditions potentially affecting HRQL in patients with prolonged weaning.</p>","PeriodicalId":20197,"journal":{"name":"Pneumologie","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141894023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Ruptured pulmonary Echinococcus granulosus cyst: A rare cause of severe pneumogenic sepsis]. [肺棘球蚴肉芽肿囊肿破裂：严重肺源性败血症的罕见病因]。
IF 1.2
Pneumologie Pub Date : 2024-08-01 Epub Date: 2024-06-10 DOI: 10.1055/a-2331-7212
Jonas Früh, Lukas Fieber, Matthias Held, Andreas Müller
{"title":"[Ruptured pulmonary Echinococcus granulosus cyst: A rare cause of severe pneumogenic sepsis].","authors":"Jonas Früh, Lukas Fieber, Matthias Held, Andreas Müller","doi":"10.1055/a-2331-7212","DOIUrl":"10.1055/a-2331-7212","url":null,"abstract":"<p><p>Parasitic infections by Echinococcus granulosus are rare in Germany, and predominantly affect individuals with a migration background. Liver and lungs are the most commonly affected organs. Pulmonary cysts often remain asymptomatic until rupture, at which point symptoms may manifest. The diagnostic approach typically involves a combination of imaging modalities and serological tests, occasionally supplemented by molecular genetic methods. Given the global movements of migration, considerations of the epidemiology of common diseases in the country of origin should also be taken into account in the differential diagnosis. We present the unusual case of a pneumogenic sepsis in a young man from Syria, where the combination of medical history alongside radiological, serological, and molecular genetic investigations ultimately led to the diagnosis of a severe pulmonary echinococcosis with rupture.</p>","PeriodicalId":20197,"journal":{"name":"Pneumologie","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141301417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Schwieriges Asthma ist nicht schweres Asthma! 难治性哮喘不是严重哮喘！
IF 1.2
Pneumologie Pub Date : 2024-08-01 Epub Date: 2024-08-19 DOI: 10.1055/a-2340-9941
Norbert K Mülleneisen
{"title":"Schwieriges Asthma ist nicht schweres Asthma!","authors":"Norbert K Mülleneisen","doi":"10.1055/a-2340-9941","DOIUrl":"https://doi.org/10.1055/a-2340-9941","url":null,"abstract":"","PeriodicalId":20197,"journal":{"name":"Pneumologie","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142005029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Pulmonary hypertension in adults with congenital heart disease in light of the 2022-ESC-PAH guidelines - Part II: Supportive therapy, special situations (pregnancy, contraception, non-cardiac surgery), targeted pharmacotherapy, organ transplantation, special management (shunt lesions, left ventricular disorders, univentricular hearts), interventions, intensive care, follow-up, future perspectives]. [根据 2022-ESC-PAH 指南对先天性心脏病成人肺动脉高压的研究--第二部分：支持性治疗、特殊情况（妊娠、避孕、非心脏手术）、针对性药物治疗、器官移植、特殊管理（分流病变、左心室疾病、单心室心脏）、干预、重症监护、随访、未来展望]。
IF 1.2
Pneumologie Pub Date : 2024-08-01 Epub Date: 2024-05-24 DOI: 10.1055/a-2274-1025
Harald Kaemmerer, Gerhard Paul Diller, Stephan Achenbach, Ingo Dähnert, Christina A Eichstaedt, Andreas Eicken, Annika Freiberger, Sebastian Freilinger, Ralf Geiger, Matthias Gorenflo, Ekkehard Grünig, Alfred Hager, Michael Huntgeburth, Ann-Sophie Kaemmerer-Suleiman, Rainer Kozlik-Feldmann, Astrid E Lammers, Nicole Nagdyman, Sebastian Michel, Kai Helge Schmidt, Anselm Uebing, Fabian von Scheidt, Christian Apitz
{"title":"[Pulmonary hypertension in adults with congenital heart disease in light of the 2022-ESC-PAH guidelines - Part II: Supportive therapy, special situations (pregnancy, contraception, non-cardiac surgery), targeted pharmacotherapy, organ transplantation, special management (shunt lesions, left ventricular disorders, univentricular hearts), interventions, intensive care, follow-up, future perspectives].","authors":"Harald Kaemmerer, Gerhard Paul Diller, Stephan Achenbach, Ingo Dähnert, Christina A Eichstaedt, Andreas Eicken, Annika Freiberger, Sebastian Freilinger, Ralf Geiger, Matthias Gorenflo, Ekkehard Grünig, Alfred Hager, Michael Huntgeburth, Ann-Sophie Kaemmerer-Suleiman, Rainer Kozlik-Feldmann, Astrid E Lammers, Nicole Nagdyman, Sebastian Michel, Kai Helge Schmidt, Anselm Uebing, Fabian von Scheidt, Christian Apitz","doi":"10.1055/a-2274-1025","DOIUrl":"10.1055/a-2274-1025","url":null,"abstract":"<p><p>The number of adults with congenital heart defects (CHD) is steadily rising and amounts to approximately 360,000 in Germany. CHD is often associated with pulmonary hypertension (PH), which may develop early in untreated CHD. Despite timely treatment of CHD, PH not infrequently persists or recurs in older age and is associated with significant morbidity and mortality.The revised European Society of Cardiology/European Respiratory Society 2022 guidelines for the diagnosis and treatment of PH represent a significant contribution to the optimized care of those affected. However, the topic of \"adults with congenital heart disease\" is addressed only relatively superficial in these guidelines. Therefore, in the present article, this topic is commented in detail from the perspective of congenital cardiology.</p>","PeriodicalId":20197,"journal":{"name":"Pneumologie","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141094109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Intended and unintended effects of e-cigarettes in clinical studies: a plea for (more) transparency]. [电子烟在临床研究中的预期效果和意外效果：要求（更多）透明度]。
IF 1.2
Pneumologie Pub Date : 2024-08-01 Epub Date: 2024-01-24 DOI: 10.1055/a-2243-9399
Reiner Hanewinkel, Sabina Ulbricht
{"title":"[Intended and unintended effects of e-cigarettes in clinical studies: a plea for (more) transparency].","authors":"Reiner Hanewinkel, Sabina Ulbricht","doi":"10.1055/a-2243-9399","DOIUrl":"10.1055/a-2243-9399","url":null,"abstract":"<p><p>E-cigarettes are used in clinical trials to facilitate smoking cessation. Due to the health risks associated with the use of e-cigarettes, the results of clinical trials should be fully reported, including continued exclusive use and dual use of tobacco and e-cigarettes. Nicotine cessation outcomes should be reported as the primary endpoint as well as the analysis of tobacco cessation alone. As there is currently no robust evidence that reducing cigarette consumption provides substantial health benefits, cigarette consumption reduction should not be used as a health outcome in clinical trials. Continued nicotine dependence should be included as an \"adverse event\" in the reporting of trial results.</p>","PeriodicalId":20197,"journal":{"name":"Pneumologie","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139545717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
YoungDGP-Pilotprojekt Pneumo Speed Dating – Innovatives Fortbildungsformat mit Zukunftspotenzial. YoungDGP 试点项目 "气动快速约会"--具有未来潜力的创新培训形式。
IF 1.2
Pneumologie Pub Date : 2024-08-01 Epub Date: 2024-08-19 DOI: 10.1055/a-2281-4767
Erik Büscher, Wolfram Windisch, Jutta Kappes, Dirk Skowasch, Michael Kreuter, Julia Wälscher
{"title":"YoungDGP-Pilotprojekt Pneumo Speed Dating – Innovatives Fortbildungsformat mit Zukunftspotenzial.","authors":"Erik Büscher, Wolfram Windisch, Jutta Kappes, Dirk Skowasch, Michael Kreuter, Julia Wälscher","doi":"10.1055/a-2281-4767","DOIUrl":"10.1055/a-2281-4767","url":null,"abstract":"","PeriodicalId":20197,"journal":{"name":"Pneumologie","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142005030","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Rare Example of abnormal vocal resonance: a case from Balzac's novel. 异常声带共鸣的罕见实例：巴尔扎克小说中的一个案例。
IF 1.2
Pneumologie Pub Date : 2024-08-01 Epub Date: 2024-02-21 DOI: 10.1055/a-2248-9672
Volodymyr Berezutskyi, Maryna Berezutska
{"title":"Rare Example of abnormal vocal resonance: a case from Balzac's novel.","authors":"Volodymyr Berezutskyi, Maryna Berezutska","doi":"10.1055/a-2248-9672","DOIUrl":"10.1055/a-2248-9672","url":null,"abstract":"<p><p>Ungewöhnliche klinische Fälle wecken bei praktizierenden Ärzten immer wieder Interesse und ermöglichen es ihnen, ihre Wissensbasis zu erweitern und ihre Fähigkeiten zum klinischen Denken zu verbessern. Der Zweck dieser Studie besteht darin, einen klinischen Fall von Stimmresonanz beim Singen bei einem schwindsüchtigen Teenager aus dem Roman \"Der Landarzt\" von Honoré de Balzac unter Verwendung induktiver und deduktiver Methoden des klinischen Denkens zu analysieren. Stimmresonanzen beim Singen in Schwindsucht können als pathognomonisches Zeichen für eine kavernöse Tuberkulose gewertet werden, da nur mit dem Bronchus verbundene Hohlräume als Helmholtz-Resonator wirken. Trotz der Einzigartigkeit ist das Gehäuse durchaus realistisch, da es nicht im Widerspruch zu den Gesetzen der Akustik steht. Praktizierende Ärzte verfügen über die Kenntnisse der medizinischen Physik, Morphologie und Physiologie, die zum Verständnis der Pathogenese der klinischen Manifestation einer Lungenhöhle erforderlich sind. Dieser Fall zeigt deutlich die Vor- und Nachteile klinischer Denkmethoden, die in der Praxis eingesetzt werden. Dank der Kombination aus Originalität und Realismus kann der Fall von Stimmresonanz aus Balzacs Roman \"Der Landarzt\" seinen rechtmäßigen Platz in der persönlichen Sammlung klinischer Fälle eines jeden Lungenarztes einnehmen.</p>","PeriodicalId":20197,"journal":{"name":"Pneumologie","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139932490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
1 Million beatmete Patienten in Deutschland: Eine komplette Übersicht über die Jahre 2019–2022. 德国 100 万名呼吸机患者：2019-2022 年完整概览。
IF 1.2
Pneumologie Pub Date : 2024-08-01 Epub Date: 2024-06-12 DOI: 10.1055/a-2341-6337
Norbert Suttorp
{"title":"1 Million beatmete Patienten in Deutschland: Eine komplette Übersicht über die Jahre 2019–2022.","authors":"Norbert Suttorp","doi":"10.1055/a-2341-6337","DOIUrl":"10.1055/a-2341-6337","url":null,"abstract":"","PeriodicalId":20197,"journal":{"name":"Pneumologie","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141311492","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Erratum: YoungDGP-Pilotprojekt Pneumo Speed Dating – Innovatives Fortbildungsformat mit Zukunftspotenzial. 勘误：YoungDGP 试点项目 "气动快速约会"--具有未来潜力的创新培训形式。
IF 1.2
Pneumologie Pub Date : 2024-08-01 Epub Date: 2024-08-22 DOI: 10.1055/a-2395-6368
E Büscher, W Windisch, J Kappes, D Skowasch, M Kreuter, J Wälscher
{"title":"Erratum: YoungDGP-Pilotprojekt Pneumo Speed Dating – Innovatives Fortbildungsformat mit Zukunftspotenzial.","authors":"E Büscher, W Windisch, J Kappes, D Skowasch, M Kreuter, J Wälscher","doi":"10.1055/a-2395-6368","DOIUrl":"https://doi.org/10.1055/a-2395-6368","url":null,"abstract":"","PeriodicalId":20197,"journal":{"name":"Pneumologie","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142036717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Brain metastases]. [脑转移]。
IF 1.2
Pneumologie Pub Date : 2024-08-01 Epub Date: 2024-01-24 DOI: 10.1055/a-2238-1840
Christian Schulz, Martin Proescholdt, Nils Ole Schmidt, Felix Steger, Daniel Heudobler
{"title":"[Brain metastases].","authors":"Christian Schulz, Martin Proescholdt, Nils Ole Schmidt, Felix Steger, Daniel Heudobler","doi":"10.1055/a-2238-1840","DOIUrl":"10.1055/a-2238-1840","url":null,"abstract":"<p><p>Cerebral metastases in patients with metastatic lung cancer are found in more than 30% of patients at baseline and manifest themselves in two out of three patients during disease evolution. For a long time, the cerebral manifestation of the disease was classified as prognostically unfavorable and hence such patients were regularly excluded from therapy studies. In the context of targeted molecular therapy strategies and established immuno-oncological systemic therapies, the blood-brain barrier no longer represents an insurmountable barrier. However, the treatment of brain metastases requires decision making in a multidisciplinary team within dedicated lung cancer and/or oncology centers. The differentiated treatment decision is based on the number, size and location of the brain metastases, neurology and general condition, comorbidities, potential life expectancy and the patient's wishes, but also tumor biology including molecular targets, extra-cranial tumor burden and availability of a CNS-effective therapy. Systemic therapies as well as neurosurgical and radiotherapeutic concepts are now often combined for optimized and prognosis-improving therapeutic strategies.</p>","PeriodicalId":20197,"journal":{"name":"Pneumologie","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139545675","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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