Physiologia plantarum最新文献

{"title":"Transcriptomics and Metabolomics Analyses Reveal New Insights Into Cold Resistance in Paeonia Veitchii.","authors":"Jiahui Zhou, Jinnan Zhang, Zhenguo Yan, Qing Yuan, Pinjie Lu, Yanlong Zhang, Xiaoxiao Zhang","doi":"10.1111/ppl.70400","DOIUrl":"https://doi.org/10.1111/ppl.70400","url":null,"abstract":"<p><p>Paeonia veitchii is an important economic plant that is known for its exceptional medicinal value and for its remarkable tolerance to cold. However, the molecular mechanisms underlying its cold tolerance remain unclear. In this study, an integrated approach combining physiological analysis and multi-omics techniques was employed to investigate the metabolic pathways and molecular mechanisms involved in the cold stress response of P. veitchii. Metabolomic analysis revealed significant changes in the levels of 61 metabolites under cold stress, with prominent increases in polyamines (e.g., p-Coumaroylputrescine, +2.97-fold) and phenolic acids (e.g., Syringic acid, +3.69-fold). Transcriptomic profiling identified 22,525 DEGs, including 3852 genes enriched in cold adaptation pathways including plant hormone signaling, MAPK signaling, and glutathione metabolism. Key regulators of polyamine and phenolic acid metabolism were identified, including aldehyde dehydrogenase, arginine decarboxylase, polyamine oxidase (PAO), S-adenosylmethionine decarboxylase, and aspartate aminotransferase, with downregulation of PAO, promoting salidroside accumulation but simultaneously suppressing methylated indole-3-acetic acid. Moreover, the reduced accumulation of flavonoids may be linked to the expression of flavonoid 3'-monooxygenase. Furthermore, it was discovered that the ETH, JA-Ile, SA, and MAPK signaling pathways play an active role in the signaling of P. veitchii roots during the response to cold stress. This study offers valuable insights into the complex regulatory mechanisms that govern the cold stress response in P. veitchii roots, thereby establishing a theoretical basis for a better understanding of its response and adaptation mechanisms to cold stress.</p>","PeriodicalId":20164,"journal":{"name":"Physiologia plantarum","volume":"177 4","pages":"e70400"},"PeriodicalIF":5.4,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144576114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Regulating Plant Architecture to Enhance the Future of Cereal Crop Production.","authors":"Nitika Sandhu, Hitashi Aggarwal, Aman Kumar, Gaurav Augustine, Ritika Vishnoi, Ajay Kumar Pandey, Harsh Chauhan, Parveen Chhuneja","doi":"10.1111/ppl.70367","DOIUrl":"https://doi.org/10.1111/ppl.70367","url":null,"abstract":"<p><p>Cereal crops such as rice, wheat, maize, and barley are vital sources of food and income for millions of people worldwide. The architecture of cereal plants, encompassing their height, branching patterns, and inflorescence structure, is crucial in determining their yield potential, adaptability to different environments, and resistance to biotic and abiotic stresses. Boosting cereal production is essential to meet the food demands of a growing population, stimulate economic growth, and ensure sustainable agriculture. Cereal plant architecture is shaped by a combination of genetic, environmental, and hormonal factors. While genetic factors are fundamental in determining plant structure, environmental conditions can influence gene expression, leading to different phenotypic outcomes. Hormones like auxin, cytokinin, and gibberellin regulate key aspects of plant architecture, including root and shoot growth, leaf expansion, and branching. Additionally, brassinosteroids and strigolactone signaling pathways are involved in tiller development in cereal crops. This review aims to provide a comprehensive analysis of the latest research on cereal plant architecture, emphasizing the genetic, environmental, and hormonal regulation. Understanding these factors can support the creation of new cereal varieties with enhanced yield and stress tolerance, contributing to global food security and sustainability amid climate change and population growth.</p>","PeriodicalId":20164,"journal":{"name":"Physiologia plantarum","volume":"177 4","pages":"e70367"},"PeriodicalIF":5.4,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144529300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Zinc Finger Transcriptional Repressor ZOS5-09 Regulates Grain Filling and Development in Rice.","authors":"Priya Jaiswal, Falah Qasim, Arunima Mahto, Ankur Vichitra, Upasana Das, Akhilesh K Tyagi, Pinky Agarwal","doi":"10.1111/ppl.70376","DOIUrl":"https://doi.org/10.1111/ppl.70376","url":null,"abstract":"<p><p>Grain size is one of the key determinants of grain yield. Our study focuses on a novel seed-preferential C₂H₂ zinc finger transcription factor, ZOS5-09 (LOC_Os05g38600) that plays an important role in regulating rice grain traits. Rice plants with the ZOS5-09 promoter::GUS construct showed high expression of ZOS5-09 in rice endosperm. In planta reporter effector assays and localization studies showed that ZOS5-09 is a nuclear-localized transcriptional repressor. It has two C₂H₂ zinc finger domains and a C-terminal NoRS (nucleolar retention signal). Ectopic and seed-preferential overexpression of ZOS5-09 resulted in lethality. Seed-preferential overexpression without NoRS was detrimental to grain filling. Rice plants with knock-down or CRISPR-based knock-out of ZOS5-09 displayed reduced grain length and weight but increased grain width. Grain size change was due to lower cell proliferation and increased cell size in the transverse direction because of downregulation of cell cycle-related genes and increased expression of expansins. Decreased expression of ZOS5-09 also resulted in reduced total starch and protein content and higher endosperm chalkiness, thus negatively affecting grain quality. ZOS5-09 directly bound to a zinc finger-binding site and regulated a seed storage protein-encoding gene, GLU6. It acted as a repressor by promoting deacetylation upon interaction with a histone deacetylase. In summary, our results indicate that an optimum expression of ZOS5-09 is essential for proper rice grain development. Our study highlights the role of a transcriptional repressor in regulating rice grain traits and improves our understanding of the transcriptional regulatory networks affecting grain size.</p>","PeriodicalId":20164,"journal":{"name":"Physiologia plantarum","volume":"177 4","pages":"e70376"},"PeriodicalIF":5.4,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144529303","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Metabolomic Analysis of the Metabolic Accumulation of Flavonoids, Anthocyanins, and Phenolic Acids in Differently Growing and Developing Blueberries.","authors":"Yu Zhang, Xiaogang Wang, Liangjie Ba, Donglan Luo, Su Xu, Xiaohong Kou, Jiaying Jin, Sen Cao","doi":"10.1111/ppl.70417","DOIUrl":"https://doi.org/10.1111/ppl.70417","url":null,"abstract":"<p><p>Flavonoids, phenolic acids, and anthocyanins are the key substances determining the color change of blueberries, but their composition and biosynthesis mechanisms in different stages of blueberry development are not clear. Accumulation of flavonoids, phenolic acids, and anthocyanins in blueberry fruits (green-G, pink-P and blue-B) from three growth stages was investigated by ultra-performance liquid chromatography tandem mass spectrometry (UPLC-MS/MS). Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analysis revealed significant differences in the biosynthesis of anthocyanins and flavonoids among fruits at three developmental stages. Weighted gene co-expression network analysis (WGCNA) further implicated four transcription factor families (MYB, bHLH, C3H, and C2H2) in the regulation of hub genes governing color development via flavonoid/anthocyanin biosynthesis in blueberry. These transcription factors may serve as key regulators of the transcriptional network and provide a basis for further research and utilization of blueberry flavonoids and anthocyanins.</p>","PeriodicalId":20164,"journal":{"name":"Physiologia plantarum","volume":"177 4","pages":"e70417"},"PeriodicalIF":5.4,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144682938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Double Edge-Sword in Antarctica: In Situ Passive Warming Exacerbates Drought and Heat Stress Differentially in the Native Vascular Species.","authors":"Jorge Gago, Marc Carriquí, Manuel Ayuso, Adriano Nunes-Nesi, Carlos María Figueroa, Alisdair Robert Fernie, María José Clemente-Moreno, Javier Gulías, Jaume Flexas, Lohegrin Alexis Cavieres, León Aloys Bravo","doi":"10.1111/ppl.70399","DOIUrl":"10.1111/ppl.70399","url":null,"abstract":"<p><p>We investigated the impact of open-top chamber (OTC) passive warming systems at molecular and ecophysiological levels on Deschampsia antarctica (DA) and Colobanthus quitensis (CQ) in Antarctica. In this field campaign, OTC led to more benign conditions early in the growing season but ultimately intensified drought stress and increased extreme heat events, affecting photosynthetic capacity, metabolism and dehydration tolerance in DA; however, CQ remained relatively unaffected. DA exhibited significant reductions in photosynthesis primarily due to stomatal and mesophyll limitations. Furthermore, DA plants grown under OTC conditions showed a notable 17% decrease in leaf mass per area (LMA), a crucial trait associated with stress tolerance. Metabolic profiling revealed an increased accumulation of osmoprotectants and protein stabilisers (soluble sugars, trehalose, myo-inositol and galactinol), secondary metabolite precursors (tryptophan and nicotinate) and cell wall constituents (xylose) in OTC-grown DA, suggesting a robust metabolic response to stress. However, these metabolic adjustments were insufficient to counteract the decline in LMA and maintain dehydration tolerance. This study thereby provides new insights into the physiological and metabolic limitations of Antarctic vascular plants under future warming and drying scenarios.</p>","PeriodicalId":20164,"journal":{"name":"Physiologia plantarum","volume":"177 4","pages":"e70399"},"PeriodicalIF":5.4,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12257275/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144626954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Spraying Cerium Oxide Nanoparticles to Optimize Morphological Structure and Physiological Response of Fragrant Rice Seedlings Under Cadmium Stress.","authors":"Pipeng Xing, Meiying Liu, Xiaojuan Pu, Jiajun Lin, Shenggang Pan, Xiangru Tang","doi":"10.1111/ppl.70384","DOIUrl":"https://doi.org/10.1111/ppl.70384","url":null,"abstract":"<p><p>Fragrant rice is highly valued for its unique aroma but is vulnerable to heavy metal stress, particularly cadmium (Cd). This study investigates the effects of cerium oxide nanoparticles (CeO₂-NPs) on growth, photosynthetic properties, antioxidant enzyme activities, and aroma synthesis in fragrant rice seedlings under Cd stress. Heavy metal contamination in agriculture, particularly cadmium, is exacerbated by its high mobility. Nanotechnology, particularly the application of cerium oxide nanoparticles (CeO₂-NPs), presents a significant yet underexplored potential for mitigating these detrimental effects. Our results demonstrate that CeO₂-NPs significantly enhance the tolerance of fragrant rice seedlings to Cd stress. This is achieved primarily by reducing Cd uptake and suppressing the expression of genes responsible for Cd uptake and translocation. CeO₂-NPs also improve the antioxidant capacity of the seedlings, alleviate the impairment of the photosynthetic system under Cd stress, and promote root and overall plant growth. Additionally, CeO₂-NPs increase the aroma content of fragrant rice by enhancing the activity of aroma-related enzymes, increasing proline content, and subsequently elevating the levels of 2-acetyl-1-pyrroline (2-AP), a key aromatic compound. The study underscores the dual role of CeO₂-NPs in mitigating Cd toxicity and enhancing aromatic quality in fragrant rice. These findings suggest that CeO₂-NPs are a promising tool for protecting and improving the quality of fragrant rice in Cd-contaminated environments, offering a potential strategy for managing heavy metal stress in agriculture.</p>","PeriodicalId":20164,"journal":{"name":"Physiologia plantarum","volume":"177 4","pages":"e70384"},"PeriodicalIF":5.4,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144591969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Phenotypic Analysis and Spatiotemporal RNA-Seq Reveal Key Phenes and Regulatory Network Cascades Under Low Nitrogen Stress in Lettuce.","authors":"Weiqi Kuang, Anan Tang, Limin Zhang, Siyu E, Jian Gao, Jing Yang, Jingkai Zhou, Yun Wang","doi":"10.1111/ppl.70329","DOIUrl":"https://doi.org/10.1111/ppl.70329","url":null,"abstract":"<p><p>The biological processes underlying nitrogen uptake and utilization represent targets for the genetic improvement of lettuce nitrogen use efficiency (NUE) to increase productivity and counter nitrogen pollution. This study investigated the growth performance and phenotypic traits of 12 lettuce (Lactuca sativa) varieties under low nitrogen (LN) conditions. Spatial and time-resolved RNA-seq of the LN-tolerance lettuce variety was conducted to explore the molecular mechanisms of the LN response. The results revealed that leaf area, root diameter, root-to-shoot ratio, root hair length, and density are key phenes that respond to LN stress. Transcriptome analysis revealed heterogeneous gene expression in roots and shoots under LN conditions. In roots, NRT2.1, NRT2.4, and NRT3.1 were upregulated, whereas NRT2.4 and NRT3.1 were downregulated in shoots. GDU1 and GDU2 were upregulated in shoots, whereas GDU2 was downregulated in roots, indicating nitrogen redistribution. In shoots, key transcription factors included MYB, ERF, GTE9, bHLH, and HSF-A7a, whereas MYB, WRKY17, Trihelix-GT-3a, HSF-A4c, ERF, and MIKC_MADS-2 were important regulators in roots, offering potential targets for improving NUE in lettuce. The time-ordered gene co-expression network revealed tissue-specific regulatory cascades under LN conditions. Specifically, roots continuously regulate metabolic processes and nutrient absorption, while shoots transition from early-stage nutrient uptake to later-stage photosynthesis and cell wall organization, reflecting distinct adaptive strategies. These phenotypic traits and nitrogen-responsive genes provide valuable targets for breeding high-NUE lettuce varieties, offering opportunities to increase nitrogen use efficiency, promote sustainable agriculture, and reduce nitrogen pollution.</p>","PeriodicalId":20164,"journal":{"name":"Physiologia plantarum","volume":"177 4","pages":"e70329"},"PeriodicalIF":5.4,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144554184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"CNGC2 Negatively Regulates Stomatal Closure and Is Not Required for flg22- and H₂O₂-Induced Guard Cell [Ca²⁺]_cyt Elevation in Arabidopsis thaliana.","authors":"Rojina Akter, Yasuhiro Inoue, Saori Masumoto, Yoshiharu Mimata, Takakazu Matsuura, Izumi C Mori, Toshiyuki Nakamura, Yoshimasa Nakamura, Yoshiyuki Murata, Shintaro Munemasa","doi":"10.1111/ppl.70396","DOIUrl":"10.1111/ppl.70396","url":null,"abstract":"<p><p>In guard cells, cytosolic Ca²⁺ acts as a second messenger that mediates abscisic acid (ABA)- and pathogen-associated molecular pattern (PAMP)-induced stomatal closure. It was reported that Arabidopsis cyclic nucleotide-gated ion channel 2 (CNGC2) functions as hydrogen peroxide (H₂O₂)- and PAMP-activated Ca²⁺-permeable channels at the plasma membrane of mesophyll cells and mediates Ca²⁺-dependent PAMP-triggered immunity. In this study, we examined the role of CNGC2 in the regulation of stomatal movement because CNGC2 is also expressed in guard cells. We found that stomata of the CNGC2 disruption mutant cngc2-3 are constitutively closed even in the absence of ABA or the flagellar-derived PAMP, flg22. Consistently, leaf temperatures of the cngc2-3 mutant were higher than those of wild-type (WT) plants. The stomatal phenotype of the cngc2-3 mutant was restored by complementation with wild-type CNGC2 under the control of the guard cell preferential promoter, pGC1. Elevation of cytosolic free Ca²⁺ concentration in guard cells induced by flg22 and H₂O₂ remained intact in the cngc2-3 mutant. The introduction of the ost1-3 mutation into the cngc2-3 background did not alter the stomatal phenotype. However, the stomatal phenotype of the cngc2-3 mutant was successfully rescued in the double disruption mutant cngc2-3aba2-2. Taken together, these results suggest that CNGC2 negatively regulates stomatal closure response and does not function as flg22- and H₂O₂-activated Ca²⁺ channels in guard cells. Though CNGC2 is responsive for H₂O₂- and flg22-induced [Ca²⁺]_cyt elevation in mesophyll cells, the involvement of CNGC2 in the response to H₂O₂ and flg22 in guard cells is questionable.</p>","PeriodicalId":20164,"journal":{"name":"Physiologia plantarum","volume":"177 4","pages":"e70396"},"PeriodicalIF":5.4,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12241493/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144601250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Symbiosomal Proteomic Analysis Reveals the Implication of Endosomal Regulators and CAPs in the Formation of Peanut Nodules.","authors":"Zhao Zheng, Wenjing Ke, Chuanliang Liu, Haomin Cai, Danting Zhu, Qingren Liu, Chuhan Ji, Lei Feng, Jun Gu, Jilei Huang, Xiaorong Wan, Yixiong Zheng, Caiji Gao","doi":"10.1111/ppl.70409","DOIUrl":"https://doi.org/10.1111/ppl.70409","url":null,"abstract":"<p><p>Arachis hypogaea (peanut) is an important leguminous crop that obtains nitrogen through symbiotic nitrogen fixation with rhizobia, with root nodules serving as the site of this symbiosis. Although the cytological characteristics and ultrastructure of root nodules in model leguminous plants have been well elucidated, research progress on peanut root nodules remains relatively limited. In this study, we characterized the spatiotemporal developmental pattern of peanut root nodules through microscopic imaging and ultrastructural analysis. Furthermore, we isolated symbiosome-enriched fractions from peanut nodules for proteomic analysis and identified 340 and 182 peanut proteins in a comprehensive proteome atlas of the peanut symbiosome membrane (SM) and peribacteroid space (PBS), respectively. Notably, our analysis revealed a significant enrichment of endosomal regulators in the SM and CAP family proteins (cysteine-rich secretory proteins, antigen 5, and pathogenesis-related 1 proteins) in the PBS. Finally, we demonstrated that AhCAP21 specifically localizes to the symbiosome, and the SM-localized AhRabA2a is essential for proper symbiosome development. Together, these findings advance our understanding of peanut nodule development and provide insights into the protein compositions and regulators in symbiosome biogenesis in peanut nodules.</p>","PeriodicalId":20164,"journal":{"name":"Physiologia plantarum","volume":"177 4","pages":"e70409"},"PeriodicalIF":5.4,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144626959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Plant Mind: Unraveling Abiotic Stress Priming, Memory, and Adaptation.","authors":"K P R Aswathi, Sami Ul-Allah, Jos T Puthur, Kadambot H M Siddique, Michael Frei, Muhammad Farooq","doi":"10.1111/ppl.70372","DOIUrl":"10.1111/ppl.70372","url":null,"abstract":"<p><p>Plants exhibit a remarkable capacity to adapt to recurrent abiotic stresses, prompting a re-evaluation of traditional views on plant responses to environmental challenges. This review explores the intricate mechanisms of stress priming, memory, and adaptation in plants. Specifically, it details the molecular and physiological processes underlying abiotic stress priming, which serve as a gateway to understanding plant memory. Stress priming fosters resilience against diverse stressors through interconnected pathways involving hormone signaling, transcriptional regulation, DNA methylation, histone modifications, and small RNAs. These epigenetic changes orchestrate stress-responsive gene expression and can, in some cases, be passed on to future generations. This review distinguishes between somatic memory, intergenerational effects, and transgenerational inheritance to avoid conceptual overlap. By connecting short-term priming to long-term adaptation and potential heritability, this article proposes a paradigm shift in how plant resilience is understood, with significant implications for crop improvement under climate stress.</p>","PeriodicalId":20164,"journal":{"name":"Physiologia plantarum","volume":"177 4","pages":"e70372"},"PeriodicalIF":5.4,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12228110/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144567697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}