PhlebologyPub Date : 2023-04-01DOI: 10.1177/02683555221150563
Daniel Westby, Baker M Ghoneim, Fiona Nolan, Mohamed Elsharkawi, Sean Maguire, Stewart R Walsh
{"title":"Varicose veins as a risk factor for venous thromboembolism in arthroplasty patients: Meta-analysis.","authors":"Daniel Westby, Baker M Ghoneim, Fiona Nolan, Mohamed Elsharkawi, Sean Maguire, Stewart R Walsh","doi":"10.1177/02683555221150563","DOIUrl":"https://doi.org/10.1177/02683555221150563","url":null,"abstract":"<p><strong>Objective: </strong>A meta-analysis to determine if patients with varicose veins are at an increased risk of venous thromboembolism (VTE) when undergoing major lower limb arthroplasty.</p><p><strong>Methods: </strong>Medline, Embase, and Cochrane Library databases were searched using appropriate terms for studies that reported post-operative VTE in patients who had lower limb arthroplasty with any history of varicose veins. Methodological quality of included studies was quantified using the Risk of Bias (ROB) assessment tools. Findings were reported using the meta-analysis of observational studies in epidemiology (MOOSE) checklist.</p><p><strong>Results: </strong>A total of 129 studies were identified with 11 observational studies being eligible for inclusion. This consisted of 265,194 patients who underwent lower limb arthroplasty, 2188 of which had pre-existing varicose veins. Overall, VTE occurred in 1845 patients, and 122 cases had varicose veins present at time of arthroplasty. Meta-analysis indicates that patients undergoing lower limb arthroplasty with varicose veins are at increased risk of having a VTE, OR 2.37, 95% CI 1.54-3.63, (<i>p</i> < 0.001). One study evaluated if previous varicose veins surgery influenced the risk of VTE in arthroplasty patients, OR 0.96 (95% CI 0.7-1.28), <i>p</i> = 0.429.</p><p><strong>Conclusions: </strong>Varicose veins and lower limb arthroplasty are known independent risk factors for VTE. There is a paucity of data regarding the risk of VTE in patients undergoing lower limb arthroplasty who have co-existing varicose veins. This meta-analysis shows that patients with varicose veins are at an increased risk of VTE when undergoing major lower limb arthroplasty. Further studies are required in order to determine if such patients should undergo varicose vein surgery before undertaking major lower limb joint replacement.</p>","PeriodicalId":20139,"journal":{"name":"Phlebology","volume":"38 3","pages":"150-156"},"PeriodicalIF":1.7,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9237563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
PhlebologyPub Date : 2023-04-01DOI: 10.1177/02683555231153019
Parsi K, Connor DE
{"title":"Authors Reply: Chronic venous disease, platelet and haemostatic abnormalities contribute to the pathogenesis of pigmented purpuric dermatoses.","authors":"Parsi K, Connor DE","doi":"10.1177/02683555231153019","DOIUrl":"https://doi.org/10.1177/02683555231153019","url":null,"abstract":"Dear Editor, We thank you for drawing our attention the letter of Yetkin et al. entitled Pigmented Purpuric Dermatosis-Ecchymosis and Chronic Venous Disease in response to our paper Chronic venous disease, platelet and haemostatic abnormalities contribute to the pathogenesis of pigmented purpuric dermatoses. The authors of the letter have erroneously interpreted ecchymosis and purpura to be synonymous with pigmented purpuric dermatosis (PPD, also known as capillaritis). While ecchymosis is the clinical manifestation of an anatomical bleed, PPD is a distinct dermatological condition with a complex aetiology that is vastly distinct from a simple purpura or ecchymosis. The diagnosis of PPD is confirmed by a biopsy of the affected lesion where histology would typically reveal a perivascular lymphocytic infiltrate and a dermal red cell extravasation. In some sub-categories of PPD, a lichenoid infiltrate, dermal spongiosis or a granulomatous component may be present. PPD is a differential diagnosis for variants of cutaneous T-cell lymphoma (CTCL) and in particular the angiocentric mycosis fungoides (CTCL) that may clinically resemble PPD. It has also been suggested that PPD may be a precursor of CTCL. Various other conditions and in particular cutaneous sarcoidosis may resemble PPD. Hence, a PPD eruption should not be dismissed as simple purpura or pigmentation and appropriate dermatological assessment including a biopsy should be carried out. The novel finding of our study is that patients with PPD would benefit from further assessment of congenital or acquired haemostatic abnormalities that result in thrombocytopenia or affect platelet function. In particular we demonstrated that drugs or supplements such as fish oil may inhibit platelet function contributing to the pathogenesis of PPD. We recommended cessation of any modifiable risk factor when clinically appropriate and treatment of an underlying chronic venous disease when present. Many dermatological conditions may appear clinically similar to non-dermatologists and the confusion is exacerbated when different conditions are titled containing a similar lexicon. Not all conditions containing the term purpura indicate simple bruising as evident from the range of conditions containing the term purpura including PPD, Henoch-Schonlein purpura (IgA vasculitis), thrombotic thrombocytopenic purpura (TTP) and immune-mediated thrombocytopenia (immune thrombocytopenic purpura; ITP). A referral to a dermatologist and appropriate histological confirmation of the clinical diagnosis is recommended when practitioners are dealing with unusual pigmented or purpuric conditions.","PeriodicalId":20139,"journal":{"name":"Phlebology","volume":"38 3","pages":"196-197"},"PeriodicalIF":1.7,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9660781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
PhlebologyPub Date : 2023-04-01DOI: 10.1177/02683555231162293
Maurizio Pagano, Daniele Bissacco, Luigi Cacace, Federica Calculli, Renato Casana, Paolo Tondi
{"title":"Are all patients with sapheno-femoral junction incompetence the same? An ultrasound analysis to potentially predict recurrence after invasive treatments.","authors":"Maurizio Pagano, Daniele Bissacco, Luigi Cacace, Federica Calculli, Renato Casana, Paolo Tondi","doi":"10.1177/02683555231162293","DOIUrl":"https://doi.org/10.1177/02683555231162293","url":null,"abstract":"<p><p>The sapheno-femoral junction (SFJ) and the great saphenous vein (GSV) are recognized as one of the main sources of reflux in chronic venous disease. Moreover, reflux time is considered as the main parameter to characterize GSV disease. Despite this, it is well-known in the clinical practice that not all patients with SFJ/GSV reflux are similar, in terms of disease severity and degree. Some other anatomical findings, such as SFJ and GSV diameters, as well as the absence/incompetence of suprasaphenic femoral valve (SFV) might be of interest to better \"quantify\" the disease severity. The aim of this paper is to describe, through a duplex scan analysis, the relationship between SFJ incompetence, GSV/SFJ diameter and SFV absence/incompetence, to identify if there are patients with \"severe\" GSV disease and a potential higher recurrence rate after invasive treatments.</p>","PeriodicalId":20139,"journal":{"name":"Phlebology","volume":"38 3","pages":"190-193"},"PeriodicalIF":1.7,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9232412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effect of the timing of iliac vein stent implantation on catheter-directed thrombolysis in acute lower extremity deep venous thrombosis patients with severe iliac vein stenosis: a retrospective study.","authors":"Chunjiang Liu, Yue Zhou, Yifeng Sun, Miaojun Xu, Guohua Wang, Liming Tang","doi":"10.1177/02683555231157566","DOIUrl":"https://doi.org/10.1177/02683555231157566","url":null,"abstract":"<p><strong>Objective: </strong>To investigate the effect of the timing of iliac vein stent implantation on catheter-directed thrombolysis (CDT) in acute lower extremity deep venous thrombosis (DVT) patients with severe iliac vein stenosis.</p><p><strong>Methods: </strong>The clinical data of 66 patients with acute lower extremity DVT complicated with severe iliac vein stenosis from May 2017 to May 2020 were retrospectively analyzed. Patients were divided into two groups by timing of iliac vein stent implantation: group A (iliac vein stent implantation before CDT treatment) for 34 and group B (iliac vein stent implantation after CDT treatment) for 32. The detumescence rate of affected limb, the thrombus clearance rate, the thrombolytic efficiency, the complication rate, the hospitalization cost, the stent patency rate within 1 year, and the scores (venous clinical severity score, Villalta, and chronic venous insufficiency questionnaire (CIVIQ) score) at 1 year postoperatively were compared between the two groups.</p><p><strong>Results: </strong>The thrombolytic efficiency of group A was higher than that of group B, while the incidence of complications and hospitalization expenses in group A were lower than those in group B. There was no statistical significance in the detumescence rate of affected limb, the thrombus clearance rate, the stent patency rate within 1 year, and the scores (VCSS, Villalta, and CIVIQ score) at 1 year postoperatively between the two groups.</p><p><strong>Conclusions: </strong>For acute lower extremity DVT patients with severe iliac vein stenosis, iliac vein stent implantation before CDT treatment can improve the thrombolytic efficiency, and reduce the incidence of complications and hospitalization costs.</p>","PeriodicalId":20139,"journal":{"name":"Phlebology","volume":"38 3","pages":"181-189"},"PeriodicalIF":1.7,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9239163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
PhlebologyPub Date : 2023-04-01DOI: 10.1177/02683555231153002
Ertan Yetkin, Hasan Atmaca, Bilal Çuğlan, Kenan Yalta
{"title":"Pigmented purpuric dermatosis-ecchymosis and chronic venous disease.","authors":"Ertan Yetkin, Hasan Atmaca, Bilal Çuğlan, Kenan Yalta","doi":"10.1177/02683555231153002","DOIUrl":"https://doi.org/10.1177/02683555231153002","url":null,"abstract":"Dear Editor, We have recently read the article published by Parsi et al. with great enthusiasm and curiosity. They have investigated the etiology of pigmented purpuric dermotoses (PPD) in lower extremity of 67 patients. Briefly the authors have assessed the association of PPD with other concurrent conditions such as bleeding diathesis, NSAID and aspirin use, chronic venous disease (CVD), and fish oil use. Eventually, they have documented that CVD has the highest rate of co-existence (76.2%) with PPD. Moreover, complete resolution of PPDs has been achieved in 95% of the treated patients. Ecchymosis, often used interchangeably with purpura, defines the larger area of discoloration of the skin due to extravasations of blood into the subcutaneous tissue. Although they have similar characteristics in terms of erythrocyte extravasations and sequential discoloration of skin due to hemoglobin catabolism, ecchymosis has been reserved for larger and more extensive area of involvement. Within this context association of CVD with PPD or ecchymosis has already been reported in literature. Ecchymosis has been found to be a sign of varicose vein in a cohort of 494 patients in which arterio occlusive disease, anti-platelet and anticoagulation use, trauma and hematologic diseases have been excluded. Moreover, significant association of muscle cramps with ecchymosis has been documented in patients with peripheral varicose veins. Ruptured superficial veins triggered by muscle contraction and subsequent extravasations of erythrocytes have been supposed to be the underlying mechanism of ecchymosis. Likewise, an independent association of ecchymosis with peripheral varicose vein has been confirmed by using the VEINES-Sym questionnaire. In this regard, Parsi et al. has corroborated that pigmented purpuric lesions or ecchymosis of lower extremities might be a sign of peripheral varicose vein. Therefore, in the absence of known hematologic disease, anti-platelet and/or anticoagulant use, presence of peripheral varicose veins should be preferentially considered in differential diagnosis of PPD or ecchymosis. Moreover, careful individual assessment of patients focusing on the presence of peripheral varicose vein and/or CVD might prevent further unnecessary diagnostic measurements for the etiology of ecchymosis.","PeriodicalId":20139,"journal":{"name":"Phlebology","volume":"38 3","pages":"194-195"},"PeriodicalIF":1.7,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9646347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
PhlebologyPub Date : 2023-03-01DOI: 10.1177/02683555231161439
Lowell S Kabnick, Katheen Ozsvath, Jorge H Ulloa
{"title":"Selected phlebological abstracts.","authors":"Lowell S Kabnick, Katheen Ozsvath, Jorge H Ulloa","doi":"10.1177/02683555231161439","DOIUrl":"https://doi.org/10.1177/02683555231161439","url":null,"abstract":"scle-rotherapy","PeriodicalId":20139,"journal":{"name":"Phlebology","volume":"38 2","pages":"135-136"},"PeriodicalIF":1.7,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9480513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
PhlebologyPub Date : 2023-03-01DOI: 10.1177/02683555221149273
Miloš D Pavlović, Spiro S Schuller, Mark M Head, David Kaiser, Maruša Jerše, Sanja Schuller Petrović
{"title":"Safety and effectiveness of indirect radiofrequency ablation (closure FAST) of incompetent great saphenous veins with Type I aneurysms: Long-term results radiofrequency ablation for saphenous aneurysms.","authors":"Miloš D Pavlović, Spiro S Schuller, Mark M Head, David Kaiser, Maruša Jerše, Sanja Schuller Petrović","doi":"10.1177/02683555221149273","DOIUrl":"https://doi.org/10.1177/02683555221149273","url":null,"abstract":"<p><strong>Background: </strong>Assess the safety and effectiveness of indirect radiofrequency ablation (RFA, Closure FAST) for the treatment of incompetent great saphenous veins (GSVs) with type 1 aneurysms.</p><p><strong>Methods: </strong>This was a retrospective analysis performed in three centers (2007-2021). All patients presenting with saphenous aneurysms close to the junction (within 2 cm) were included. They were treated with RFA. Phlebectomies and/or sclerotherapy were performed during the same treatment session. Duplex ultrasound (DUS) was performed early after the procedure and then, more than a year later.</p><p><strong>Results: </strong>Eight patients (11 limbs) were included between June 2007 and May 2021 with a median diameter of the GSV aneurysm 21 mm (IQR 17.2-23.4). No severe adverse events occurred apart from one endovenous heat-induced thrombosis (EHIT) class III (9.1%). After more than a year (mean 7.2 ± 4.2, median 8 years), none of the aneurysms was present on DUS and the truncal obliteration rate was 100%.</p><p><strong>Conclusion: </strong>RFA appears to be a safe and effective treatment for patients presenting with incompetent saphenous veins with the type 1 aneurysm.</p>","PeriodicalId":20139,"journal":{"name":"Phlebology","volume":"38 2","pages":"129-132"},"PeriodicalIF":1.7,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9096711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
PhlebologyPub Date : 2023-03-01DOI: 10.1177/02683555221147472
Francisco J Torres-Quintanilla, José R Azpiri-López, Maria E Romero-Ibarguengoitia, Tadeo H Ponce-Sierra, Eunice P Martínez-Gallegos
{"title":"Improving thromboprophylaxis in the medical inpatients: The role of the resident in an academic hospital.","authors":"Francisco J Torres-Quintanilla, José R Azpiri-López, Maria E Romero-Ibarguengoitia, Tadeo H Ponce-Sierra, Eunice P Martínez-Gallegos","doi":"10.1177/02683555221147472","DOIUrl":"https://doi.org/10.1177/02683555221147472","url":null,"abstract":"<p><strong>Introduction: </strong>Venous thromboembolism (VTE) is one of the main causes of preventable in-hospital death. It is recommended for hospitals to have an appropriate thromboprophylaxis (TP) protocol to avoid VTE complications.</p><p><strong>Objective: </strong>To determine the effect of the resident physician feedback to the staff physician in TP appropriateness after the Caprini RAM score implementation.</p><p><strong>Methods: </strong>Caprini RAM was implemented by the residents in medical patients. Patients were divided in low, moderate, high, and highest-risk groups, with TP recommendation accordingly. In cases with inadequate TP, the resident provided feedback to the staff physician for adjustment. Change to appropriate TP was assessed retrospectively.</p><p><strong>Results: </strong>A total of 265 records were included. Before intervention, 193 (72.8%) patients had appropriate TP and post-intervention, 207 (78.1%) patients received adequate TP (<i>p</i> < .001).</p><p><strong>Conclusions: </strong>Feedback from the internal medicine resident to staff physician improves appropriate TP in medical inpatients as a quality of care strategy.</p>","PeriodicalId":20139,"journal":{"name":"Phlebology","volume":"38 2","pages":"91-95"},"PeriodicalIF":1.7,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10844920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
PhlebologyPub Date : 2023-03-01DOI: 10.1177/02683555221150147
Görkem Yiğit
{"title":"Outcomes of cyanoacrylate closure of the truncal varicose vein insufficiency: A comparison between young and elderly patients.","authors":"Görkem Yiğit","doi":"10.1177/02683555221150147","DOIUrl":"https://doi.org/10.1177/02683555221150147","url":null,"abstract":"<p><strong>Objectives: </strong>Cyanoacrylate closure (CAC) procedure has become an alternative treatment method that has become increasingly popular in the treatment of chronic venous insufficiency (CVI) in recent years. The present study was designed to assess the feasibility, tolerance, results, and efficacy of CAC for truncal varicosities in elderly population.</p><p><strong>Methods: </strong>In this retrospective single-center observational cohort study, CAC procedure was performed in 160 patients (184 limbs) with truncal varicose vein insufficiency. The patients were divided into two groups: elderly group, and younger group. The primary outcome of this study was to assess the feasibility, tolerance, and safety of the CAC procedure for truncal varicosities in elderly population over 70 years. The Venous Clinical Severity Score (VCSS), visual analogue scale of pain (VASP) and occlusion rate of the treated target veins of the patients were evaluated and compared among groups. The secondary outcomes were to evaluate and compare technical success, mortality, major adverse events, and other postoperative complications between the groups.</p><p><strong>Results: </strong>All operations were carried out under local anesthesia. There were no technical failures or device-related complications. Anatomic success rate was 100% after procedures. The occlusion rate for the elderly group at 2 weeks, 6 months, and 12 months was 100%, 92.3%, and 92.3%, respectively, while the occlusion rate for the younger group was 100%, 97%, and 94.7%, respectively. There was no significant difference in occlusion rates between two groups (<i>p</i> > .05) (Log Rank = 0,231). Improvement in the VCSSs was statistically significant between baseline and 12 months after procedure in both groups (<i>p</i> < .001). Improvement in the VASPs was statistically significant between baseline and 2 weeks after procedure in both groups (<i>p</i> < .001). There were no symptoms or signs of sural nerve injury, hematoma, or phlebitis in either group.</p><p><strong>Conclusions: </strong>Although it has some potential risks, it is conceivable that the CAC procedure may be applied in selected fit elderly patients for the treatment of CVI. Age appeared to have no effect on the early and mid-term prognosis of the CAC procedure performed in the study cohort.</p>","PeriodicalId":20139,"journal":{"name":"Phlebology","volume":"38 2","pages":"119-128"},"PeriodicalIF":1.7,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10845153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
PhlebologyPub Date : 2023-03-01DOI: 10.1177/02683555221149587
Tianan Huang, Wenbin Ding, Yonghai Jin, Jie Jin, Xiaowen Deng, Li Liang, Zhuo Chen, Xin Hong
{"title":"Multi-factor analysis of failure for modified single-session Angiojet rheolytic thrombectomy in treatment of acute iliofemoral venous thrombosis from iliac vein compression syndrome.","authors":"Tianan Huang, Wenbin Ding, Yonghai Jin, Jie Jin, Xiaowen Deng, Li Liang, Zhuo Chen, Xin Hong","doi":"10.1177/02683555221149587","DOIUrl":"https://doi.org/10.1177/02683555221149587","url":null,"abstract":"<p><strong>Purpose: </strong>To explore the risk factors of failure for modified single-session Angiojet rheolytic thrombectomy combined with directed iliac vein stenting, directed filter retrieval in the treatment of iliac vein compression with iliofemoral vein thrombosis.</p><p><strong>Methods: </strong>During September 2017 to September 2021, 278 patients with DVT were retrospectively analyzed and 203 were eligible for inclusion. All patients were tried to take modified single-session Angiojet rheolytic thrombectomy combined with directed iliac vein stenting, directed filter retrieval treatment. The perioperative factors were analyzed between groups: group 1-modified single-session therapy succeed, and group 2-modified single-session therapy failed. The high risk factors of failure group were evaluated by logistic regression analysis.</p><p><strong>Results: </strong>48 patients failed in modified single-session therapy, up to 23.64%. Single factor analysis indicated that there were five independent risk factors related with the failure (<i>p</i> < 0.05), including course of disease longer than 7 days, lumbar degeneration-related iliac vein compression syndrome (dIVCS), antegrade vein access, balloon-assisted cracking thrombus, and suction time. Logistic regression analysis indicated that course of disease longer than 7 days (OR = 19.642.95%CI:6.776∼56.933), dIVCS (OR = 11.586.95%CI:4.016∼33.427) were high risk factors for modified single-session therapy failed, antegrade vein access (OR = 0.171.95%CI:0.047∼0.614) and balloon-assisted cracking thrombus (OR = 0.157.95%CI:0.045∼0.542) were protective factors for therapy failure (<i>p</i> < 0.05).</p><p><strong>Conclusions: </strong>Long course of disease and dIVCS are the high risk factors for failure of modified single-session Angiojet rheolytic thrombectomy combined with directed iliac vein stenting, directed filter retrieval in the treatment of iliac vein compression syndrome (IVCS). But, antegrade vein access and balloon-assisted cracking thrombus intraoperatively may improve the success rate of modified single-session treatment.</p>","PeriodicalId":20139,"journal":{"name":"Phlebology","volume":"38 2","pages":"96-102"},"PeriodicalIF":1.7,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10861884","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}