Plastic and reconstructive surgery最新文献

{"title":"Results from the Multicenter Nonrandomized BREAST-II Trial for Total Breast Reconstruction Solely Using Autologous Fat Transfer: 1-Year Follow-Up.","authors":"Wessel B W van der Venne, Kyrah S Goeree, Jamilla L M Wederfoort, Juliëtte E Hommes, Sander M J van Kuijk, Esther M Heuts, Andrzej A Piatkowski de Grzymala, Chantal M Mouës","doi":"10.1097/PRS.0000000000012742","DOIUrl":"10.1097/PRS.0000000000012742","url":null,"abstract":"<p><strong>Background: </strong>Autologous fat transfer (AFT) has emerged as a promising technique for total breast reconstruction after mastectomy, particularly in cases unsuitable for other reconstruction methods. Evaluation of its efficacy, safety, and impact on quality of life (QoL) is essential. The authors assessed efficacy and safety outcomes of AFT as postmastectomy total breast reconstruction based on 12-month follow-up data from the BREAST-II trial.</p><p><strong>Methods: </strong>This multicenter nonrandomized clinical trial included women 18 years of age or older with a history of or planned mastectomy across 8 Dutch hospitals. Participants underwent multiple AFT sessions combined with external expansion using the Evebra device, with a maximum of 5 sessions over 12 months. The primary outcome was QoL measured by BREAST-Q and BODY-Q. Secondary outcomes included safety (eg, serious adverse events), operating time, hospital stay, and number of sessions.</p><p><strong>Results: </strong>A total of 229 women were included. At 12 months after AFT, significant improvements were observed in Psychosocial Well-Being (+5.72 ± 16.79), Sexual Well-Being (+8.05 ± 19.61), Physical Well-Being: Chest (+5.97 ± 20.44), and Satisfaction with Chest (+17.22 ± 27.27) (all P < 0.001). BODY-Q scores showed significant increases in satisfaction with the abdomen, back, body, hips/outer thighs, inner thighs, and scars (all P < 0.001). Among 805 AFT sessions, 52 adverse events occurred (6.46% complication rate). Hospital stays were less than 1 day per session.</p><p><strong>Conclusions: </strong>AFT is an effective and safe total breast reconstruction technique after mastectomy, significantly improving QoL with low complication rates. These findings support AFT as a valuable addition to breast reconstruction options.</p>","PeriodicalId":20128,"journal":{"name":"Plastic and reconstructive surgery","volume":" ","pages":"567e-577e"},"PeriodicalIF":3.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146019259","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Plastic Surgery Exposure in Medical Education: A Cross-Sectional Analysis of Liaison Committee on Medical Education-Accredited Medical Schools.","authors":"Terrence C Green, Brianna M Peet, Lauren S Lowe, Lee Yang, Kathleen Gu, Jarrod T Bogue","doi":"10.1097/PRS.0000000000013117","DOIUrl":"10.1097/PRS.0000000000013117","url":null,"abstract":"","PeriodicalId":20128,"journal":{"name":"Plastic and reconstructive surgery","volume":" ","pages":"743e-744e"},"PeriodicalIF":3.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147699522","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Breast Cancer Awareness Month 2026.","authors":"Evan Matros","doi":"10.1097/PRS.0000000000013277","DOIUrl":"https://doi.org/10.1097/PRS.0000000000013277","url":null,"abstract":"","PeriodicalId":20128,"journal":{"name":"Plastic and reconstructive surgery","volume":"158 4","pages":"685-687"},"PeriodicalIF":3.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149081372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reply: Unmasking Inequality: The Current State of Health Disparities Research in Plastic Surgery.","authors":"Isabel A Snee, Kishan S Shah, Luke J Llaurado, Laura K Tom","doi":"10.1097/PRS.0000000000013131","DOIUrl":"https://doi.org/10.1097/PRS.0000000000013131","url":null,"abstract":"","PeriodicalId":20128,"journal":{"name":"Plastic and reconstructive surgery","volume":"158 4","pages":"738e-739e"},"PeriodicalIF":3.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149081765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Discussion: Do Long-Term Thoracic Adaptations Occur in Pediatric Microtia Patients after Costal Cartilage Harvesting?","authors":"David P Perrault, Jordan W Swanson","doi":"10.1097/PRS.0000000000012893","DOIUrl":"https://doi.org/10.1097/PRS.0000000000012893","url":null,"abstract":"","PeriodicalId":20128,"journal":{"name":"Plastic and reconstructive surgery","volume":"158 4","pages":"684e-685e"},"PeriodicalIF":3.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149081629","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Discussion: Retrorectus Mesh Use in Deep Inferior Epigastric Perforator Flaps to Reduce Abdominal Morbidity.","authors":"Moustapha Hamdi","doi":"10.1097/PRS.0000000000012964","DOIUrl":"https://doi.org/10.1097/PRS.0000000000012964","url":null,"abstract":"","PeriodicalId":20128,"journal":{"name":"Plastic and reconstructive surgery","volume":"158 4","pages":"552e-553e"},"PeriodicalIF":3.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149081787","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reply: Versatility of the Lateral Intercostal Artery Perforator Flap for Enhancing Outcomes of Autologous Breast Reconstruction.","authors":"J Bryce Olenczak, Ashleigh M Francis, Rene D Largo","doi":"10.1097/PRS.0000000000013145","DOIUrl":"https://doi.org/10.1097/PRS.0000000000013145","url":null,"abstract":"","PeriodicalId":20128,"journal":{"name":"Plastic and reconstructive surgery","volume":"158 4","pages":"730e-731e"},"PeriodicalIF":3.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149081809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preventing Cheesewire and Hump Recurrence in Low Strip Preservation Rhinoplasty.","authors":"Rubén Guilarte, Ignacio Romero-López","doi":"10.1097/PRS.0000000000012653","DOIUrl":"https://doi.org/10.1097/PRS.0000000000012653","url":null,"abstract":"<p><strong>Background: </strong>Hump recurrence represents a potential complication of preservation rhinoplasty. In the low septal strip technique, the quadrangular cartilage functions as a rotational advancement flap anchored to the anterior nasal spine. Proper fixation is crucial to prevent hump recurrence caused by backward rotation of the flap.</p><p><strong>Methods: </strong>All primary preservation rhinoplasties performed by the same surgeon with the low septal strip septoplasty technique between January of 2021 and December of 2023 were analyzed retrospectively, comparing conventional fixation with mattress sutures to a novel technique, referred to as kite fixation. The primary outcome variables were the presence or absence of hump recurrence and the need for revision surgery.</p><p><strong>Results: </strong>A total of 823 patients were included in the study, with 405 in the conventional fixation group and 418 in the kite-shaped fixation group. Demographic characteristics were comparable between the groups. Statistically significant differences were observed in terms of hump recurrence (4.6% versus 1.2%) and the necessity of revision surgery (4.3% versus 1.1%).</p><p><strong>Conclusions: </strong>Hump recurrence and minihumps remain significant drawbacks in preservation rhinoplasty. Proper fixation of the rotated septal flap is crucial to achieving long-term postoperative stability. Redistributing the tension of the suture loops into a triangular configuration, known as the kite-shaped method, has proven to be a simple, effective, and reproducible technique.</p>","PeriodicalId":20128,"journal":{"name":"Plastic and reconstructive surgery","volume":"158 4","pages":"607e-614e"},"PeriodicalIF":3.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149081775","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bioengineered Exosomal Hair Growth Factor Complex in Upregulating HFDPCs and Downregulating Il-6 and IL-1β in Hair Growth.","authors":"Arundha Abrol, Garima Balpande, Mahesh Gosavi, Komal Doshi, Disha Singhal, Yuti Nakhwa, Kim Su Jung, Jung Dai Hyun","doi":"10.1097/PRS.0000000000012724","DOIUrl":"10.1097/PRS.0000000000012724","url":null,"abstract":"<p><strong>Background: </strong>This study evaluated the safety and therapeutic efficacy of a novel hair growth factor complex that combines bioengineered exosomes with the biomimetic polypeptides in QR678 Nexo to treat androgenetic alopecia. Its effectiveness was rigorously evaluated through both in vitro and in vivo experimental paradigms.</p><p><strong>Methods: </strong>Human follicle dermal papilla cells (HFDPCs) were cultured in vitro and treated with the novel formulation. Cell viability and proliferative responses were quantified using MTT assays. Anti-inflammatory efficacy was assessed by measuring mRNA expression levels of interleukin (IL)-6 and IL-1β. Then, an open-label prospective clinical study including 85 human participants (Indian men and women between 20 and 60 years of age) was performed, with efficacy metrics including hair pull tests, photographic evaluations, videomicroscopic assessments, and patient-reported outcomes across 8 treatment sessions. Safety profiles were monitored through physical examinations and participant-reported adverse events.</p><p><strong>Results: </strong>The in vitro findings showed a statistically significant enhancement in HFDPC proliferation (172.4% relative to control) and downregulation of IL-6 and IL-1β mRNA levels. In vivo, the hair pull test revealed a reduction in hair shedding, from an average of 7.8 to 1.4 hairs. Videomicroscopic analyses indicated elevations in terminal hair counts and shaft diameters, with sustained enhancements in hair density 2 months after treatment.</p><p><strong>Conclusions: </strong>The bioengineered exosomal hair growth factor complex is a promising minimally invasive intervention for managing hair loss. It demonstrates enhanced therapeutic efficacy while minimizing adverse effects, marking a significant advancement in regenerative dermatology.</p><p><strong>Clinical relevance statement: </strong>In patients with androgenetic alopecia, treatment with a bioengineered exosomal hair growth factor complex was associated with reduced hair shedding and improved terminal hair count, shaft diameter, and photographic assessment scores. This approach may offer a promising adjunctive regenerative option, although controlled long-term studies are needed.</p>","PeriodicalId":20128,"journal":{"name":"Plastic and reconstructive surgery","volume":" ","pages":"632e-644e"},"PeriodicalIF":3.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145763647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hemiobturator Nerve-Innervated Latissimus Dorsi Muscle for Restoring Voluntary Voiding: Anatomic Study and Clinical Application.","authors":"Ke Xu, Wenjun Li, Yaobin Yin, Feng Li, Haidong Wang, Haiming Sui, Jiyao Zou, Jiansheng Mu, Shufeng Wang","doi":"10.1097/PRS.0000000000012721","DOIUrl":"10.1097/PRS.0000000000012721","url":null,"abstract":"<p><strong>Summary: </strong>This study presents a modified latissimus dorsi detrusor myoplasty technique using the hemiobturator nerve for neurogenic underactive bladder reconstruction. Anatomical studies ( n = 22 hemipelves) revealed that the diameters of the anterior (mean, 0.209 cm) and posterior (mean, 0.199 cm) branches matched the diameter of the thoracodorsal nerve (1-way analysis of variance, P = 0.557), confirming their ideal donor potential. Latissimus dorsi detrusor myoplasty using the posterior branch of the intrapelvic obturator nerve as the donor nerve was performed in 5 patients with neurogenic underactive bladder. Of 5 patients, 4 (80%) achieved restored voluntary voiding postoperatively, with postvoid residual volume decreasing significantly from 308.5 (187.5) to 62.0 (58.8) mL ( P = 0.042) and bladder contractility index improving significantly from 12.8 (5.7) to 151.9 (46.5) ( P = 0.007). These results demonstrate that latissimus dorsi detrusor myoplasty using the hemiobturator nerve is an effective surgical approach for functional detrusor reconstruction in patients with neurogenic underactive bladder.</p>","PeriodicalId":20128,"journal":{"name":"Plastic and reconstructive surgery","volume":" ","pages":"659-663"},"PeriodicalIF":3.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145763688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}