Sarah Tepe, Kian Daneshi, Jenny Ziembicki, Elizabeth L Dale Slater, Francesco M Egro
{"title":"Financial Conflicts of Interest in ReCell Research: A Network-Level Perspective on Transparency.","authors":"Sarah Tepe, Kian Daneshi, Jenny Ziembicki, Elizabeth L Dale Slater, Francesco M Egro","doi":"10.1097/PRS.0000000000013480","DOIUrl":"https://doi.org/10.1097/PRS.0000000000013480","url":null,"abstract":"","PeriodicalId":20128,"journal":{"name":"Plastic and reconstructive surgery","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2026-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149128260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Chu Luan Nguyen, Ramandeep Kaur, Sze Ki Melanie Tam, Deepali Poels, Basilie Teoh, Jue Li Seah, Belinda Chan, Farhad Azimi, Susannah Graham, Cindy Mak, Sanjay Kumar Warrier
{"title":"Effectiveness of Closed-Incision Negative Pressure Wound Therapy in Non-Autologous Breast Surgery: A Systematic Review and Meta-Analysis.","authors":"Chu Luan Nguyen, Ramandeep Kaur, Sze Ki Melanie Tam, Deepali Poels, Basilie Teoh, Jue Li Seah, Belinda Chan, Farhad Azimi, Susannah Graham, Cindy Mak, Sanjay Kumar Warrier","doi":"10.1097/PRS.0000000000013481","DOIUrl":"https://doi.org/10.1097/PRS.0000000000013481","url":null,"abstract":"<p><strong>Background: </strong>Prophylactic closed-incision negative pressure wound therapy (ciNPWT) may reduce risk of postoperative wound complications, but its use in breast surgery remains uncertain due to lack of breast-specific recommendations in guidelines. This meta-analysis addresses this gap by evaluating the efficacy of ciNPWT versus standard dressings in non-autologous breast surgery.</p><p><strong>Methods: </strong>A meta-analysis of RCTs and observational studies comparing ciNPWT versus standard dressings in patients undergoing mastectomy, implant-based breast reconstruction, or mammoplasty was conducted following PRISMA (from inception to September 2025). Outcomes were total wound complications, surgical site infection, wound dehiscence, necrosis, seroma, haematoma, re-operation, and implant loss. Risk of bias (RoB2, ROBINS-I) and certainty (GRADE) were assessed, and data pooled (RStudio). Registered with PROSPERO (CRD420251002005).</p><p><strong>Results: </strong>Twenty studies (6 RCTs, 14 observational) involving 2287 patients (3376 breasts) were included. ciNPWT significantly reduced total wound complications (RR 0.56, 95%CI 0.42-0.74; p<0.0001; I²=71.9%; moderate certainty), corresponding to an absolute risk reduction (ARR) of 14% (31.8% to 17.8%). Wound dehiscence (RR 0.48, 95%CI 0.29-0.79; p=0.0037; I²=33.4%) and necrosis (RR 0.67, 95%CI 0.48-0.94; p=0.0187; I²=7.5%) were also significantly reduced. Subgroup analyses suggested stronger effects in BMI ≥30 (RR 0.41 vs 0.61 for BMI <30) and with -125 mmHg settings (RR 0.46 vs 0.65 for -80 mmHg), though differences were not statistically significant (p>0.20).</p><p><strong>Conclusion: </strong>Moderate-certainty evidence indicates that ciNPWT reduces postoperative wound complications-particularly dehiscence and necrosis-with a clinically meaningful ARR of 14% for total wound complications. Refining patient selection and device configuration may further enhance its applicability.</p>","PeriodicalId":20128,"journal":{"name":"Plastic and reconstructive surgery","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2026-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149128278","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kanishk Satish, Ferris Zeitouni, Jasmine N Craig, Manav M Patel, Venkat K Rao
{"title":"The VIDEO Checklist: An Evidence-Informed Quality Framework for Plastic Surgery Education on YouTube.","authors":"Kanishk Satish, Ferris Zeitouni, Jasmine N Craig, Manav M Patel, Venkat K Rao","doi":"10.1097/PRS.0000000000013492","DOIUrl":"https://doi.org/10.1097/PRS.0000000000013492","url":null,"abstract":"","PeriodicalId":20128,"journal":{"name":"Plastic and reconstructive surgery","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2026-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149128394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Unified Approach to the Correction of Male Torso Deformities After Massive Weight Loss: A 443-Patient Consecutive Series.","authors":"Murat Diyarbakirlioglu, Yunus Dogan, Fatih Cinar","doi":"10.1097/PRS.0000000000013493","DOIUrl":"https://doi.org/10.1097/PRS.0000000000013493","url":null,"abstract":"<p><p>Although numerous techniques have been described, standardized approaches for comprehensive male torso reconstruction remain limited. This study presents a unified approach integrating circumferential planning, chest reshaping, and abdominal contouring. A retrospective review was performed of 443 consecutive male MWL patients treated between 2018 and 2024. All patients underwent a standardized protocol combining posterior body lift, chest reduction/mastopexy, and either standard or fleur-de-lis (FDL) abdominoplasty. Preoperative planning incorporated Pascal's Rule of 16 for circumferential marking, while chest management utilized a pedicle-length-based decision pathway. Closure techniques and postoperative management, including compression therapy and lymphatic massage, were standardized. Outcomes were assessed using BODY-Q patient-reported outcome measures and prospectively recorded complications. Mean BMI was 29.6 (range, 22.4-34.3), and mean follow-up was 7 months. Mean tissue resection weights were 1006 g for posterior body lift and 2148 g for abdominoplasty, with approximately 240 g removed per breast. Complications included 13 (2.9%) breast hematomas, 16 (3.6%) abdominal hematomas, 8 (1.8%) partial nipple-areola complex necroses, 1 T-junction necrosis requiring grafting, 4 (0.9%) hypertrophic scars, and 52 (11.7%) seromas. Revision surgery was required in five patients. Significant improvements were observed across all BODY-Q domains, with satisfaction scores increasing from the low 40s preoperatively to above 80 postoperatively (p < 0.001). A unified approach to male MWL torso reconstruction provides safe, reproducible, and reliable outcomes. Standardized planning, objective chest management criteria, consistent closure techniques, and structured postoperative care contribute to low complication rates and high patient satisfaction. Level of Evidence: IV.</p>","PeriodicalId":20128,"journal":{"name":"Plastic and reconstructive surgery","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2026-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149128319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Amitesh Verma, Alexis B Jacobson, Thomas J Sorenson, J Rodrigo Diaz-Siso, Andrew C Prince, Adam Jacobson, Jamie P Levine
{"title":"Robotic Microsurgery with Conventional Microscopy: An Alternative to the Exoscope Configuration.","authors":"Amitesh Verma, Alexis B Jacobson, Thomas J Sorenson, J Rodrigo Diaz-Siso, Andrew C Prince, Adam Jacobson, Jamie P Levine","doi":"10.1097/PRS.0000000000013491","DOIUrl":"https://doi.org/10.1097/PRS.0000000000013491","url":null,"abstract":"","PeriodicalId":20128,"journal":{"name":"Plastic and reconstructive surgery","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2026-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149128364","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alvise Montanari, Antonio Paoli, Vincenzo Vindigni, Franco Bassetto
{"title":"Effects of Omega-3 Polyunsaturated Fatty Acids on Inflammation Resolution and Angiogenesis in Fat Grafts in a Controlled Mouse Model.","authors":"Alvise Montanari, Antonio Paoli, Vincenzo Vindigni, Franco Bassetto","doi":"10.1097/PRS.0000000000012897","DOIUrl":"10.1097/PRS.0000000000012897","url":null,"abstract":"","PeriodicalId":20128,"journal":{"name":"Plastic and reconstructive surgery","volume":" ","pages":"736e-737e"},"PeriodicalIF":3.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146133138","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yusuke Shimizu, Yoshikazu Inoue, Yoshihiro Sowa, Naoki Matsuura, Rikako Matsuura, Reiko Asato, Taiki Nagatsuka, Hiroshi Sunami, Edward H Ntege
{"title":"Reply: Adipose-Derived Stem Cell-Enhanced versus Conventional Fat Grafting for Breast Reconstruction: A Systematic Review and Meta-Analysis.","authors":"Yusuke Shimizu, Yoshikazu Inoue, Yoshihiro Sowa, Naoki Matsuura, Rikako Matsuura, Reiko Asato, Taiki Nagatsuka, Hiroshi Sunami, Edward H Ntege","doi":"10.1097/PRS.0000000000013238","DOIUrl":"https://doi.org/10.1097/PRS.0000000000013238","url":null,"abstract":"","PeriodicalId":20128,"journal":{"name":"Plastic and reconstructive surgery","volume":"158 4","pages":"732e-733e"},"PeriodicalIF":3.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149081735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Micaela J Tobin, Audrey K Mustoe, Sophia Ahn, Mohammed Yamin, Tricia Mae Raquepo, Anirudh Kulkarni, Manuela Neira, Sarah J Karinja, Bernard T Lee, Ryan P Cauley
{"title":"Body Mass Index, Comorbidities, and the New Lancet Obesity Definition: Implications for Risk Analysis in Plastic and Reconstructive Surgery.","authors":"Micaela J Tobin, Audrey K Mustoe, Sophia Ahn, Mohammed Yamin, Tricia Mae Raquepo, Anirudh Kulkarni, Manuela Neira, Sarah J Karinja, Bernard T Lee, Ryan P Cauley","doi":"10.1097/PRS.0000000000012830","DOIUrl":"10.1097/PRS.0000000000012830","url":null,"abstract":"<p><strong>Background: </strong>The Lancet Diabetes & Endocrinology Commission on the Definition and Diagnosis of Clinical Obesity proposed a new definition of obesity that de-emphasizes body mass index (BMI) in favor of adiposity-related comorbidities. This study was performed to evaluate the relevance of this paradigm shift to plastic and reconstructive surgery (PRS) by analyzing the effects of BMI and adiposity-related comorbidities on 30-day complication rates.</p><p><strong>Methods: </strong>The TriNetX health database was queried for patients undergoing PRS procedures. Patients were stratified by BMI categories and presence or absence of adiposity-related comorbidities. Cox regression analyses were performed to determine hazard ratios (HRs) for 30-day complications with subset analyses performed based on procedural complexity.</p><p><strong>Results: </strong>Among 957,985 patients, those with a BMI between 25 and 39.9 and comorbidities (HR, 1.05; P < 0.001) or a BMI of 40 or higher (HR, 1.40; P < 0.0001) had significantly higher complication risks compared with normal-weight patients. Without comorbidities, patients with a BMI between 25 and 29.9 had a lower risk (HR, 0.83; P < 0.0001) and those with a BMI between 30 and 34.9 showed similar risk (HR, 0.99; P = 0.62) to normal-weight patients. An inflection point occurred at BMI values above 35, where the complication risk increased without comorbidities. Subset analysis revealed that BMI effects were most pronounced in body contouring procedures, with patients having a BMI of 25 or higher showing significantly increased risk, regardless of comorbidity status.</p><p><strong>Conclusions: </strong>These findings partially support the new obesity definition in the context of PRS. For patients with BMI values of 25 through 34.9 without comorbidities, weight loss may not change surgical risk. Comprehensive assessment of comorbidities should be considered for patients with a BMI between 25 and 34.9, and weight loss or other risk-mitigation strategies, such as glucagon-like peptide-1 receptor agonists, may be recommended for patients with a BMI of 35 or higher.</p>","PeriodicalId":20128,"journal":{"name":"Plastic and reconstructive surgery","volume":" ","pages":"718e-726e"},"PeriodicalIF":3.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146011842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"GLP-1 Receptor Agonists versus Bariatric Surgery: A Global Health Network Analysis of Panniculectomy Outcomes.","authors":"Savannah C Braud, Peyton Terry, Saïd C Azoury","doi":"10.1097/PRS.0000000000012955","DOIUrl":"10.1097/PRS.0000000000012955","url":null,"abstract":"<p><strong>Background: </strong>With the increase in medically assisted weight loss, procedures such as panniculectomy are becoming more common. The surgical impact of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) remains unclear, particularly compared with bariatric surgery. The authors compared panniculectomy outcomes and perioperative laboratory values in patients with previous GLP-1 RA use versus bariatric surgery.</p><p><strong>Methods: </strong>The TriNetX Global Research Network was queried to identify patients who underwent panniculectomy after either GLP-1 RA use or bariatric surgery. Cohorts were formed using codes (eg, Current Procedural Terminology, International Classification of Diseases, 10th Revision) and perioperative laboratory values were compared between groups, including hemoglobin A1c (HgA1c), body mass index (BMI), low-density lipoprotein, triglycerides, and albumin. Propensity score matching for age, sex, race, HbA1c, BMI, and triglyceride levels was performed to stabilize baseline metabolic profiles and allow balanced comparison of postoperative outcomes, including cellulitis, hematoma, seroma, hemorrhage, wound dehiscence, surgical site infection, and abscess formation.</p><p><strong>Results: </strong>Data from 177,467,699 patients across 150 health care organizations (2020 through 2025) were analyzed. Among all patients who underwent panniculectomy ( n = 24,645), 6060 had preoperative GLP-1 RA use and 4142 had previous bariatric surgery. GLP-1 RA users exhibited higher perioperative triglycerides, HbA1c, BMI, and low-density lipoprotein (all P < 0.05). Multivariable regression demonstrated lower odds of cellulitis (odds ratio [OR], 0.62 [95% CI, 0.47 to 0.83]; P = 0.0015), seroma (OR, 0.77 [95% CI, 0.59 to 0.89]; P = 0.026), and hemorrhage (OR, 0.51 [95% CI, 0.30 to 0.89]; P = 0.016) in the GLP-1 RA cohort.</p><p><strong>Conclusion: </strong>Patients who achieve weight loss with GLP-1 RAs, as opposed to bariatric surgery, may experience fewer postoperative complications after panniculectomy.</p>","PeriodicalId":20128,"journal":{"name":"Plastic and reconstructive surgery","volume":" ","pages":"601-608"},"PeriodicalIF":3.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147271885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Discussion: Major Anatomic Variations of the Upper Extremity Superficial Lymphatic System.","authors":"Rajiv P Parikh, Laura K Tom","doi":"10.1097/PRS.0000000000013002","DOIUrl":"https://doi.org/10.1097/PRS.0000000000013002","url":null,"abstract":"","PeriodicalId":20128,"journal":{"name":"Plastic and reconstructive surgery","volume":"158 4","pages":"565e-566e"},"PeriodicalIF":3.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149081689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}