Sijie Sun, Biyao Zheng, Chenglong Wang, Keming Wang
{"title":"Efficacy and Safety of Recombinant Type III Humanized Collagen Solution Injection for the Treatment of Melasma in the Chinese Population.","authors":"Sijie Sun, Biyao Zheng, Chenglong Wang, Keming Wang","doi":"10.1097/PRS.0000000000012597","DOIUrl":"10.1097/PRS.0000000000012597","url":null,"abstract":"","PeriodicalId":20128,"journal":{"name":"Plastic and reconstructive surgery","volume":" ","pages":"812e-815e"},"PeriodicalIF":3.4,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145482708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ali Modabber, Aischa Troost, Mark Ooms, Harshal Patel, Andre Schüppen, Florian Peters, Frank Hölzle, Ferdinand Binkofski
{"title":"Evaluation of Sensibility of Noninnervated, Intraoral, Microsurgically Transferred Flaps.","authors":"Ali Modabber, Aischa Troost, Mark Ooms, Harshal Patel, Andre Schüppen, Florian Peters, Frank Hölzle, Ferdinand Binkofski","doi":"10.1097/PRS.0000000000012529","DOIUrl":"10.1097/PRS.0000000000012529","url":null,"abstract":"<p><strong>Background: </strong>This study investigated sensory recovery of microvascular free flaps in the oral cavity with functional magnetic resonance imaging to assess activation in the primary sensory cortex (S1).</p><p><strong>Methods: </strong>The study included 20 patients with sensory recovery at the flap site in the tongue or floor of mouth after ablative cancer surgery that involved unilateral resection of the lingual nerve and reconstruction with a radial free forearm flap, anterolateral thigh flap, or lower leg perforator flap without nerve readaptation between 2012 and 2019. Control nonflap and contralateral flap sites were electrically stimulated with a patient-specific, sensation-inducing voltage for 10 minutes with 30-second on/off intervals. During this process, functional magnetic resonance imaging was conducted simultaneously to assess the signal area and level in S1.</p><p><strong>Results: </strong>The stimulation voltage was higher at the flap site than at the control nonflap site (6.0 versus 3.0 V; P < 0.001). The signal area activated upon stimulation of the flap and control nonflap site was located in the cortical area representing the lingual nerve. The signal level in S1 upon stimulation of the flap site was similar to that upon stimulation of the control nonflap site (3.2 versus 3.5 T; P = 0.751).</p><p><strong>Conclusion: </strong>Activation of the cortical area representing the lingual nerve upon stimulation of the flap site implies that sensory recovery of microvascular free flaps in the tongue and floor of mouth region involves nerve ingrowth from the remaining lingual nerve into the flap tissue.</p>","PeriodicalId":20128,"journal":{"name":"Plastic and reconstructive surgery","volume":" ","pages":"733e-741e"},"PeriodicalIF":3.4,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145293130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ronnie L Shammas, Lillian A Boe, Jennifer Wang, Jacob Levy, Benjamin Wagner, Jonas A Nelson, Evan Matros, Peter G Cordeiro, Babak J Mehrara
{"title":"Impact of Prior Radiation on Postoperative Complications following Elective Implant Exchange.","authors":"Ronnie L Shammas, Lillian A Boe, Jennifer Wang, Jacob Levy, Benjamin Wagner, Jonas A Nelson, Evan Matros, Peter G Cordeiro, Babak J Mehrara","doi":"10.1097/PRS.0000000000012496","DOIUrl":"10.1097/PRS.0000000000012496","url":null,"abstract":"<p><strong>Background: </strong>The indications for postmastectomy radiation therapy continue to expand. Although radiation therapy is associated with higher rates of complications, many patients undergo implant-based breast reconstruction despite radiation and will eventually require elective exchange of their permanent implant. However, the risks of elective implant exchange in the previously irradiated patient remain unknown.</p><p><strong>Methods: </strong>A single-institution retrospective review was conducted of patients who underwent 2-stage implant-based breast reconstruction followed by elective implant exchange between 2010 and 2024. Patients were stratified by history of radiation, and the primary outcome was the incidence of postoperative complications following elective implant exchange. Logistic regression evaluated the association between prior radiation and postoperative complications.</p><p><strong>Results: </strong>A total of 1369 patients were included, and 244 (18%) underwent radiation and elective implant exchange. The overall complication rate was 5.6%, with significantly higher rates of complications among irradiated patients (13% versus 3.9%; P < 0.001). The incidence of infection (11% versus 2%; P < 0.001), reconstructive failure (4.9% versus 0.2%; P < 0.001), and prosthetic exposure (4.5% versus 0.2%; P < 0.001) was higher in irradiated versus nonirradiated patients. Radiation was independently associated with higher odds of any postoperative complication (OR, 3.51; 95% CI, 2.15 to 5.68; P < 0.001) and infection (OR, 6.19; 95% CI, 3.45 to 11.2; P < 0.001).</p><p><strong>Conclusions: </strong>Patients with prior radiation therapy who undergo elective implant exchange experience significantly higher complication rates; however, the rate of reconstructive failure is 5%. These findings support elective implant exchange as a viable option in appropriately selected patients and underscore the importance of careful patient selection and thorough preoperative counseling to optimize outcomes in this high-risk population.</p>","PeriodicalId":20128,"journal":{"name":"Plastic and reconstructive surgery","volume":" ","pages":"649e-656e"},"PeriodicalIF":3.4,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145302657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Woo Yeon Han, Seong John Han, Jin Sup Eom, Eun Key Kim, Hyun Ho Han
{"title":"A Comparative Study of Wraparound versus Anterior Coverage Placement of Acellular Dermal Matrix in Prepectoral Breast Reconstruction: Correction.","authors":"Woo Yeon Han, Seong John Han, Jin Sup Eom, Eun Key Kim, Hyun Ho Han","doi":"10.1097/PRS.0000000000013068","DOIUrl":"10.1097/PRS.0000000000013068","url":null,"abstract":"","PeriodicalId":20128,"journal":{"name":"Plastic and reconstructive surgery","volume":"157 5","pages":"956"},"PeriodicalIF":3.4,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147778439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Discussion: Anatomical Reconstruction of the Abdoninal Wall through Fat Grafting and Modified Plication Technique in the Abdominal Rectus.","authors":"Nishant Ganesh Kumar, Sam S Jejurikar","doi":"10.1097/PRS.0000000000012664","DOIUrl":"10.1097/PRS.0000000000012664","url":null,"abstract":"","PeriodicalId":20128,"journal":{"name":"Plastic and reconstructive surgery","volume":"157 5","pages":"849-850"},"PeriodicalIF":3.4,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147778511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Won Suk Kook, Kyungmin Kim, Insuck Suh, Jun Won Lee
{"title":"Versatile Usability of Lateral Crural Strut Graft for Correction of Various Nasal Tip Deformities in Secondary Rhinoplasty in Asians.","authors":"Won Suk Kook, Kyungmin Kim, Insuck Suh, Jun Won Lee","doi":"10.1097/PRS.0000000000012423","DOIUrl":"10.1097/PRS.0000000000012423","url":null,"abstract":"<p><strong>Background: </strong>The insertion of implants and tip plasties have been performed in Asian patients for an attractive and higher nasal profile, which can result in diverse tip deformations such as notching, pinching, alar retraction, incompetent external valve, deviated tip, cephalic rotation, and lateral crus malposition because of inappropriate manipulation of the lower lateral cartilage and/or silicone capsular contracture. This study aimed to investigate the effectiveness and utility of applying a lateral crural strut graft (LCSG) as a consistent and appropriate surgical method to correct various nasal tip deformities that occur as complications following rhinoplasty in Asian patients.</p><p><strong>Methods: </strong>The authors prospectively studied 37 patients with a minimum follow-up of 12 months among 53 patients who underwent secondary rhinoplasty, including LCSG, between January of 2016 and December of 2020. The results were assessed using the Rhinoplasty Outcome Evaluation scale preoperatively and more than 12 months postoperatively.</p><p><strong>Results: </strong>Two cases of asymmetric nostril and tip, 1 visible LCSG (bulging) and 1 external SS score, was 30.41 preoperatively and 75.90 postoperatively ( P < 0.001). All subgroups of tip deformities exhibited increased Rhinoplasty Outcome Evaluation scores after the surgery, with the subgroup demonstrating the highest change being \"lateral crural deformities,\" and the lowest change being \"tip deviation\" ( P < 0.005).</p><p><strong>Conclusion: </strong>In Asian patients, LCSG using autogenous cartilage would be a useful and versatile option for various types of nasal tip deformities in secondary rhinoplasty, which can effectively improve tip appearance, symmetry, and external valve function, and can also lengthen the contracted nose.</p>","PeriodicalId":20128,"journal":{"name":"Plastic and reconstructive surgery","volume":" ","pages":"677e-684e"},"PeriodicalIF":3.4,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13132067/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145024001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kevin C Chung, Sunitha Malay, Patricia B Burns, Hyungjin M Kim, Jamie Ki
{"title":"Predictors of Disease Severity for Ulnar Neuropathy at the Elbow: Analysis from a Randomized Clinical Trial.","authors":"Kevin C Chung, Sunitha Malay, Patricia B Burns, Hyungjin M Kim, Jamie Ki","doi":"10.1097/PRS.0000000000012472","DOIUrl":"10.1097/PRS.0000000000012472","url":null,"abstract":"<p><strong>Background: </strong>Ulnar neuropathy at the elbow (UNE) is the second most common nerve compression in the upper extremity. Painful paresthesias in fingers progress to muscle weakness and atrophy, impairing activities of daily living. Despite the common occurrence and effects on quality of life, risk factors that predispose to UNE and contribute to disease severity have not been thoroughly investigated.</p><p><strong>Methods: </strong>Patients enrolled in the Clinical Trial for Surgery of the Ulnar Nerve at the Elbow (SUN) were included. Data on patient demographics, distance traveled, disease duration, and comorbidities collected at the time of enrollment before surgery were used for this analysis. Ordinal logistic regression was used to determine risk factors associated with 3-level UNE severity.</p><p><strong>Results: </strong>The 225 study participants included in this analysis had an average age of 51 years. Age (odds ratio, 1.05 [95% CI, 1.03, 1.08]; P < 0.001) and disease duration (odds ratio, 0.71 [95% CI, 0.54, 0.93]; P = 0.01) were significantly associated with disease severity. Patients with longer disease duration before surgery were less likely to have severe disease.</p><p><strong>Conclusions: </strong>In this National Institutes of Health-funded clinical trial, distance traveled and comorbidities were not associated with severity of UNE. Patients with longer disease duration were less inclined to seek treatment sooner, likely owing to mild disease severity. The results show that distance from a treatment center is not a limitation for UNE treatment. Older individuals are at increased risk of severe disease and can benefit from early referral and treatment.</p>","PeriodicalId":20128,"journal":{"name":"Plastic and reconstructive surgery","volume":" ","pages":"742e-750e"},"PeriodicalIF":3.4,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145131636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Katya Remy, Josip Plascevic, Kenechi Iwelumo, Matthew A DePamphilis, Uriel Rangel-Sanchez, Shirley Shue, Dieter Manstein, William G Austen, Katherine H Carruthers
{"title":"Beyond the Incision: Incidence and Risk Factors of Hypertrophic Scarring following Gender-Affirming Mastectomy.","authors":"Katya Remy, Josip Plascevic, Kenechi Iwelumo, Matthew A DePamphilis, Uriel Rangel-Sanchez, Shirley Shue, Dieter Manstein, William G Austen, Katherine H Carruthers","doi":"10.1097/PRS.0000000000012536","DOIUrl":"10.1097/PRS.0000000000012536","url":null,"abstract":"<p><strong>Background: </strong>Gender-affirming mastectomy (GAM) is the most common gender-affirming operation. However, the double-incision technique involves long horizontal chest incisions, which may be prone to hypertrophic scarring (HS). Despite the potential functional and psychosocial morbidity of HS, limited research has investigated its occurrence in this patient population. This study evaluated the incidence and risk factors of HS following GAM.</p><p><strong>Methods: </strong>A retrospective study was conducted of double-incision GAM patients from 2020 to 2024. Data included demographics, comorbidities, androgen therapy, postoperative complications including HS, corticosteroid injections, and scar revision. Multivariable regression was performed.</p><p><strong>Results: </strong>A total of 241 patients were included. HS developed in 16.6%, of whom 50% underwent corticosteroid injections and 5% underwent scar revision. Non-White race was significantly associated with higher rates of HS (26.5% versus 14.1%; OR, 2.7; 95% CI, 1.2 to 6.0; P = 0.018), HS requiring corticosteroid injections (16.3% versus 6.3%; P = 0.023), and scar revision (4.1% versus 0.0%; P = 0.041). Perioperative androgen use (68.5% of patients) was significantly associated with higher rates of HS (20.0% versus 9.2%; OR, 2.6; 95% CI, 1.0 to 6.4; P = 0.028). Age, body mass index, comorbidities, nicotine use, previous breast surgery, and mastectomy weight were not significant risk factors. Average follow-up was 5.2 ± 4.5 months.</p><p><strong>Conclusions: </strong>HS is a common postoperative complication following GAM, with non-White race and androgen therapy identified as significant risk factors. Patients should be counseled regarding their individual risk profile. High-risk patients should benefit from early preventive and therapeutic interventions. Future research should investigate perioperative androgen management that balances optimal scarring outcomes and patients' broader gender-affirming goals.</p>","PeriodicalId":20128,"journal":{"name":"Plastic and reconstructive surgery","volume":" ","pages":"668e-676e"},"PeriodicalIF":3.4,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145293194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}