Pharmacophore最新文献_第2页

The Clinical and Pathological Characteristics of Neonatal Cholestasis 新生儿胆汁淤积症的临床与病理特点

Pharmacophore Pub Date : 2023-01-01 DOI: 10.51847/oeqw0zufby

Nizar Bakir Yahya, Ali Abdulghani Ramadhan

引用次数: 0

Psychological Distress Prediction Based on Maladaptive Cognitive Schemas and Anxiety with Random Forest Regression Algorithm 基于不良认知图式和焦虑的心理困扰预测与随机森林回归算法

Pharmacophore Pub Date : 2023-01-01 DOI: 10.51847/ukrb1pafyv

Cristian Delcea, Ana Simona Bululoi, Manuela Gyorgy, Dana Rad

{"title":"Psychological Distress Prediction Based on Maladaptive Cognitive Schemas and Anxiety with Random Forest Regression Algorithm","authors":"Cristian Delcea, Ana Simona Bululoi, Manuela Gyorgy, Dana Rad","doi":"10.51847/ukrb1pafyv","DOIUrl":"https://doi.org/10.51847/ukrb1pafyv","url":null,"abstract":"Psychological distress represents a complex and pervasive concern impacting individuals globally, characterized by a wide spectrum of emotional, cognitive, and physiological experiences. This multifaceted phenomenon is frequently intertwined with the presence of maladaptive cognitive schemas and heightened levels of anxiety, both recognized as contributing factors. Accurate prediction of psychological distress is of paramount significance for clinicians, researchers, and healthcare practitioners as it can drive early interventions, and personalized treatment plans, and optimize resource allocation. This research delves into the predictive capabilities of maladaptive cognitive schemas and anxiety in the context of psychological distress, employing the Random Forest Regression (RFR) algorithm. The RFR algorithm, a powerful ensemble learning method, offers the potential to comprehensively explore the intricate interplay of variables and predictors, enhancing the precision of psychological distress prediction. By harnessing the capabilities of this advanced algorithm, we seek to provide a more robust framework for understanding, assessing, and addressing psychological distress. This research aspires to illuminate the predictive potential of maladaptive cognitive schemas and anxiety, thereby contributing to the development of more effective early interventions and personalized treatment strategies. Ultimately, this study holds the promise of significantly improving our capacity to predict and intervene in cases of psychological distress, ultimately enhancing the well-being of individuals and the efficiency of healthcare delivery. This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-Share Alike 4.0 License, which allows others to remix, tweak, and build upon the work non commercially, as long as the author is credited and the new creations are licensed under the identical terms.","PeriodicalId":20012,"journal":{"name":"Pharmacophore","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135611267","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Anti-Inflammatory and Antifungal Activity of Zinc Oxide Nanoparticle Using Red Sandalwood Extract 紫檀提取物氧化锌纳米颗粒抗炎抑菌活性研究

IF 0.5

Pharmacophore Pub Date : 2023-01-01 DOI: 10.51847/igbzzfdf54

A. Yuvaraj, R. Priyadharshini, Rajesh Kumar, P. Sinduja

引用次数: 1

The Effectiveness of The Use of Macrolide Antibiotic in Infectious Diseases 大环内酯类抗生素在感染性疾病中的应用效果

IF 0.5

Pharmacophore Pub Date : 2023-01-01 DOI: 10.51847/divrexre3e

Maret Khamzatovna Rasueva, Alina Zamudinovna Medalieva, Polina Dmitrievna Shengelaya, Dunya Chingiz Kizi Allahverdiyeva, Anastasia Konstantinovna Pule, Zurab Aslanovich Gasanov

引用次数: 1

Risk Factors and Prevention of Cardiovascular Dysfunctions After Spinal Cord Injuries. A Literature Review 脊髓损伤后心血管功能障碍的危险因素及预防。文献综述

IF 0.5

Pharmacophore Pub Date : 2023-01-01 DOI: 10.51847/iae3qqag4f

Radu Fodor, Florica Voiță-Mekereș, M. Indrieș, Corina Beiușanu, Gineta Andreescu, Ioan Bogdan Voiță, Hassan Noor, T. Maghiar

{"title":"Risk Factors and Prevention of Cardiovascular Dysfunctions After Spinal Cord Injuries. A Literature Review","authors":"Radu Fodor, Florica Voiță-Mekereș, M. Indrieș, Corina Beiușanu, Gineta Andreescu, Ioan Bogdan Voiță, Hassan Noor, T. Maghiar","doi":"10.51847/iae3qqag4f","DOIUrl":"https://doi.org/10.51847/iae3qqag4f","url":null,"abstract":"This paper aims to analyze the potentially increased cardiovascular risk factors after spinal cord injury (SCI). Taking into account the pathophysiological mechanism of SCI, clinical presentation, and short-and long-term effects, this paper evaluates the prevalence of cardiovascular disorders. Reduced physical activity, low HDL cholesterol, an increase in body fat percentage, poor glucose tolerance, insulin resistance, psychosocial factors, and the hypothesised impacts of SCI on emerging risk factors are all potential increased cardiovascular risk factors following SCI. Nutritional counselling and intervention are especially crucial because people with SCI frequently eat less than is ideal. Screening for risk factors and a worldwide assessment of the risk of coronary heart disease are the first steps in prevention. People with chronic SCI are more likely to have poor glucose tolerance, insulin resistance, and hyperinsulinemia, according to reports. Important therapies for these patients include weight management, dietary adjustments, exercise, and glycemic control. Successful prevention to lower the risk of cardiovascular disease requires both patient and physician motivation. This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-Share Alike 4.0 License, which allows others to remix, tweak, and build upon the work non commercially, as long as the author is credited and the new creations are licensed under the identical terms.","PeriodicalId":20012,"journal":{"name":"Pharmacophore","volume":"1 1","pages":""},"PeriodicalIF":0.5,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70823746","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Antioxidant and Hepatoprotective Activity of Ephedra alata Extracts against Intoxication with Deltamethrin Pesticide in Male Rats 麻黄提取物对溴氰菊酯农药中毒大鼠的抗氧化及保肝作用

IF 0.5

Pharmacophore Pub Date : 2023-01-01 DOI: 10.51847/jvqlbdzpr6

Ali Boutlelis Djahra, Fatia Zoubiri, M. Benkaddour, Soulef Gouasmia

引用次数: 0

Analyzes Regarding the Cytotoxicity of ZnSO 4 Excess on Cell Division 过量znso4对细胞分裂的细胞毒性分析

IF 0.5

Pharmacophore Pub Date : 2023-01-01 DOI: 10.51847/7xj78ykqic

Sărac Ioan, P. Irina, Camen Dorin- Dumitru, Onisan Emilian, Memete Adriana- Ramona, G. Mariana

引用次数: 0

Anticancer Potential of Compounds Bearing Thiazolidin-4-one Scaffold: Comprehensive Review 含噻唑烷-4- 1支架化合物的抗癌潜力综述

IF 0.5

Pharmacophore Pub Date : 2023-01-01 DOI: 10.51847/ohzuia1yg6

Dalbir Singh, Mona Piplani, H. Kharkwal, S. Murugesan, Yogendra Pratap Singh, A. Aggarwal, Subhash Chander

引用次数: 1

Prevalence of Malaria Among COVID-19, Exhibit Severity, Management, and Outcome COVID-19中疟疾的流行、表现严重程度、管理和结果

IF 0.5

Pharmacophore Pub Date : 2023-01-01 DOI: 10.51847/twwfp3c6s4

Manal Adam Motkhatr, Musa Mohamed Khier, Sufian Khalid Mohamed, M. Elamin, W. A. Khan, H. Badri, A. Osman

{"title":"Prevalence of Malaria Among COVID-19, Exhibit Severity, Management, and Outcome","authors":"Manal Adam Motkhatr, Musa Mohamed Khier, Sufian Khalid Mohamed, M. Elamin, W. A. Khan, H. Badri, A. Osman","doi":"10.51847/twwfp3c6s4","DOIUrl":"https://doi.org/10.51847/twwfp3c6s4","url":null,"abstract":"Coronavirus disease (COVID-19) is an infectious disease caused by a new coronavirus strain. Malaria is a parasitic disease caused by protozoan parasites of the genus Plasmodium, transmitted by mosquitoes of the genus Anopheles. The dual infection of malaria and COVID-19 is not fully understood or reported. We aimed to identify the association between malaria and COVID-19, its severity, management, and clinical outcome. This is a prospective hospital-based study conducted in isolation centers in Khartoum state during the period from October to December 2020. We used the total coverage method as a sampling technique to include participants from Khartoum isolation. We included 143 participants chosen from three centers. Data were collected from the patients and their files for those who met inclusion criteria using a questionnaire as a study tool filled out by the principal researcher. All participants in this study were COVID-19 patients diagnosed by PCR. Malaria was diagnosed in 115 patients (80.4%), and fever was the most common presenting symptom that occurred in all patients followed by fatigability in 125 (87.4%), cough in 115 (80.4), and headache in 83 (58.1%). This study found an association between malaria and COVID-19. And revealed that there is a better outcome for the patient with malaria and COVID-19 compared to those without malaria (p-value=0.036). This study","PeriodicalId":20012,"journal":{"name":"Pharmacophore","volume":"1 1","pages":""},"PeriodicalIF":0.5,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70835302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Awareness of Physicians about Stroke in Emergency Settings in the Al-Jouf Region, Saudi Arabia 沙特阿拉伯Al-Jouf地区紧急情况下医生对中风的认识

IF 0.5

Pharmacophore Pub Date : 2023-01-01 DOI: 10.51847/vfwqex21f5

B. Alomair, A. M. S. Alabid, F. Alrayes, R. B. Almusayyab, Ola Ali Almajed, F. Albalawi, Z. M. Alruwaili

引用次数: 1