Prevalence of Malaria Among COVID-19, Exhibit Severity, Management, and Outcome

IF 0.5
Pharmacophore Pub Date : 2023-01-01 DOI:10.51847/twwfp3c6s4
Manal Adam Motkhatr, Musa Mohamed Khier, Sufian Khalid Mohamed, M. Elamin, W. A. Khan, H. Badri, A. Osman
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Abstract

Coronavirus disease (COVID-19) is an infectious disease caused by a new coronavirus strain. Malaria is a parasitic disease caused by protozoan parasites of the genus Plasmodium, transmitted by mosquitoes of the genus Anopheles. The dual infection of malaria and COVID-19 is not fully understood or reported. We aimed to identify the association between malaria and COVID-19, its severity, management, and clinical outcome. This is a prospective hospital-based study conducted in isolation centers in Khartoum state during the period from October to December 2020. We used the total coverage method as a sampling technique to include participants from Khartoum isolation. We included 143 participants chosen from three centers. Data were collected from the patients and their files for those who met inclusion criteria using a questionnaire as a study tool filled out by the principal researcher. All participants in this study were COVID-19 patients diagnosed by PCR. Malaria was diagnosed in 115 patients (80.4%), and fever was the most common presenting symptom that occurred in all patients followed by fatigability in 125 (87.4%), cough in 115 (80.4), and headache in 83 (58.1%). This study found an association between malaria and COVID-19. And revealed that there is a better outcome for the patient with malaria and COVID-19 compared to those without malaria (p-value=0.036). This study
COVID-19中疟疾的流行、表现严重程度、管理和结果
冠状病毒病(COVID-19)是一种由新型冠状病毒株引起的传染病。疟疾是一种由疟原虫属原生动物寄生虫引起的寄生虫病,由按蚊属蚊子传播。疟疾和COVID-19的双重感染尚未得到充分了解或报道。我们的目的是确定疟疾与COVID-19之间的关系、其严重程度、管理和临床结果。这是一项基于医院的前瞻性研究,于2020年10月至12月期间在喀土穆州的隔离中心进行。我们采用总覆盖率法作为抽样技术,纳入喀土穆隔离区参与者。我们从三个中心挑选了143名参与者。从符合纳入标准的患者及其档案中收集数据,使用调查问卷作为研究工具,由首席研究员填写。本研究所有参与者均为PCR诊断的COVID-19患者。115例确诊为疟疾(80.4%),发热是所有患者中最常见的症状,其次是疲劳125例(87.4%)、咳嗽115例(80.4%)和头痛83例(58.1%)。这项研究发现了疟疾和COVID-19之间的联系。结果显示,与没有疟疾的患者相比,疟疾和COVID-19患者的预后更好(p值=0.036)。本研究
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Pharmacophore
Pharmacophore PHARMACOLOGY & PHARMACY-
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