{"title":"Acute Pharyngitis: Diagnosis and Management.","authors":"Lourdes Eguiguren, Alice I Sato, Kari A Neemann","doi":"10.1542/pir.2025-006811","DOIUrl":"https://doi.org/10.1542/pir.2025-006811","url":null,"abstract":"","PeriodicalId":20007,"journal":{"name":"Pediatrics in review","volume":"47 5","pages":"294-296"},"PeriodicalIF":1.6,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147819471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Case of Recalcitrant Stridor in a Teenager.","authors":"Sergio S Cobos, Matthew B Wysong","doi":"10.1542/pir.2025-006882","DOIUrl":"https://doi.org/10.1542/pir.2025-006882","url":null,"abstract":"","PeriodicalId":20007,"journal":{"name":"Pediatrics in review","volume":"47 5","pages":"279-281"},"PeriodicalIF":1.6,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147819384","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pediatric Hyphema.","authors":"Victor N Oboli","doi":"10.1542/pir.2024-006714","DOIUrl":"https://doi.org/10.1542/pir.2024-006714","url":null,"abstract":"","PeriodicalId":20007,"journal":{"name":"Pediatrics in review","volume":"47 5","pages":"262-273"},"PeriodicalIF":1.6,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147819436","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nouran Ibrahim, Lisa Swartz Topor, Irina Gorbounova, Monica Serrano-Gonzalez
{"title":"Lack of Linear Growth Acceleration in a Child With Severe Obesity.","authors":"Nouran Ibrahim, Lisa Swartz Topor, Irina Gorbounova, Monica Serrano-Gonzalez","doi":"10.1542/pir.2025-006836","DOIUrl":"https://doi.org/10.1542/pir.2025-006836","url":null,"abstract":"","PeriodicalId":20007,"journal":{"name":"Pediatrics in review","volume":"47 5","pages":"282-285"},"PeriodicalIF":1.6,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147819488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"An Adolescent Abdominal Ache.","authors":"Julia Lo Cascio, Clara E Mayoral, Joshua I Chan","doi":"10.1542/pir.2025-006968","DOIUrl":"https://doi.org/10.1542/pir.2025-006968","url":null,"abstract":"","PeriodicalId":20007,"journal":{"name":"Pediatrics in review","volume":"47 5","pages":"274-278"},"PeriodicalIF":1.6,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147819452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Persistent Biphasic Stridor in a 19-Month-Old Girl With Viral Croup.","authors":"Elizabeth M Clifton, Eliaz Brumer","doi":"10.1542/pir.2025-006905","DOIUrl":"https://doi.org/10.1542/pir.2025-006905","url":null,"abstract":"","PeriodicalId":20007,"journal":{"name":"Pediatrics in review","volume":"47 5","pages":"286-289"},"PeriodicalIF":1.6,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147819476","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Dynamic Neck Mass in an Infant: Expanding the Differential.","authors":"Amy Gu, Simon C Kao, Anna Schmitz","doi":"10.1542/pir.2025-006879","DOIUrl":"https://doi.org/10.1542/pir.2025-006879","url":null,"abstract":"","PeriodicalId":20007,"journal":{"name":"Pediatrics in review","volume":"47 5","pages":"297-300"},"PeriodicalIF":1.6,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147819433","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Marie T Berg, Silvia Maria Del Rocio Delgado-Villalta, Catalina Bazacliu
{"title":"Bronchopulmonary Dysplasia: A Contemporary Review for Pediatric Practice.","authors":"Marie T Berg, Silvia Maria Del Rocio Delgado-Villalta, Catalina Bazacliu","doi":"10.1542/pir.2024-006701","DOIUrl":"10.1542/pir.2024-006701","url":null,"abstract":"<p><p>Bronchopulmonary dysplasia (BPD) remains a significant source of morbidity and mortality among preterm infants, especially those born before 28 weeks gestation. Although the survival of preterm infants has improved, the incidence of BPD remains high among extremely low birth weight infants. The pathogenesis of BPD involves inflammation and oxidative stress, leading to impaired alveolarization and dysregulated development of the pulmonary vasculature. Mechanical ventilation, oxygen toxicity, inflammation, and nutritional deficiencies, as well as genetic susceptibility, can increase the risk for and/or severity of BPD. Infants with moderate to severe BPD require prolonged respiratory support and are at risk for respiratory tract infections, pulmonary hypertension, growth failure, and neurodevelopmental impairment. Diagnosis and classification of BPD are based on assessment of an infant's oxygen needs and respiratory support requirement at 36 weeks postmenstrual age. Management of BPD emphasizes minimizing exposure to mechanical ventilation and oxygen toxicity, use of caffeine, and optimizing nutrition. The use of pharmacologic therapies, such as corticosteroids, diuretics, and beta-agonists, is limited to select patients given an uncertain risk-benefit profile. After discharge, infants with BPD require multidisciplinary follow-up to monitor respiratory health and manage supplemental oxygen, to monitor and support growth and feeding, and to assess neurodevelopment and coordinate early intervention services. These infants face high risks of rehospitalization, infections, pulmonary hypertension, and systemic hypertension. Although many children experience a gradual improvement, long-term follow-up should include a multidisciplinary and family-centered approach including pulmonologists, dietitians, gastroenterologists, therapists (speech-occupational and physical), and case management.</p>","PeriodicalId":20007,"journal":{"name":"Pediatrics in review","volume":"47 5","pages":"251-261"},"PeriodicalIF":1.5,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147819478","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Clinical Review of Congenital and Perinatal Infections: From Womb to Follow-Up.","authors":"Ayhan Ceri, Nazlı Dilay Gültekin","doi":"10.1542/pir.2025-006983","DOIUrl":"10.1542/pir.2025-006983","url":null,"abstract":"<p><p>The acronym \"TORCH\" was originally introduced in 1974 by Dr Nahmias to collectively describe the most common pathogens responsible for congenital and perinatal infections, including Toxoplasma gondii, others, rubella virus, cytomegalovirus (CMV), and herpes simplex virus. With advances in diagnostic capabilities and expanded epidemiologic surveillance, the list of recognized congenital pathogens has grown to include syphilis, varicella-zoster virus, Zika virus, HIV, parvovirus B19, and lymphocytic choriomeningitis virus. While the TORCH acronym continues to be widely used in clinical and educational settings, it no longer encompasses the full spectrum of pathogens implicated in perinatally acquired and in utero infections. A more nuanced and inclusive approach to the diagnosis and management of congenital infections is required. These vertically transmitted pathogens can disrupt fetal development, leading to outcomes ranging from subclinical disease to severe neurologic impairment, sensorineural hearing loss, or fetal demise. Epidemiologic trends vary globally: CMV is more prevalent in low-income countries, while congenital rubella is rare in regions with successful vaccination programs. The Zika virus outbreak underscored the need for early recognition of emerging threats to fetal health. Despite their potentially serious consequences, TORCH infections are frequently underdiagnosed due to nonspecific clinical presentations, diagnostic limitations, and inconsistencies in screening practices. Misinterpretation of serologic results and delays in diagnosis may lead to preventable complications. This review synthesizes current evidence on TORCH infections, emphasizing clinical manifestations, diagnostic strategies, therapeutic approaches, and long-term follow-up. A proposed multidisciplinary model aimed at improving perinatal screening and neonatal outcomes is offered.</p>","PeriodicalId":20007,"journal":{"name":"Pediatrics in review","volume":"47 5","pages":"241-250"},"PeriodicalIF":1.6,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147819361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Immune Thrombocytopenia in Children.","authors":"Lily Dolatshahi, Amani Ashraf","doi":"10.1542/pir.2025-006782","DOIUrl":"https://doi.org/10.1542/pir.2025-006782","url":null,"abstract":"<p><p>Immune thrombocytopenia (ITP) is one of the most common acquired bleeding disorders. ITP is characterized by a low platelet count in the setting of a normal hemoglobin and white blood cell count. ITP classifications are dependent on inciting factors and duration of the episodes. The management of ITP is usually guided on severity of symptoms, with life-threatening bleeding prompting the most extensive response. However, there is also a push to treat symptoms of ITP that affect quality of life. Understanding, diagnosing, and treating patients with ITP requires expertise in the rapidly growing field of autoimmune disorders.</p>","PeriodicalId":20007,"journal":{"name":"Pediatrics in review","volume":"47 4","pages":"209-216"},"PeriodicalIF":1.6,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147593736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}