Pediatrics in review最新文献

Recognizing a Few of the Vaccine-Preventable Diseases: Part 2. 认识到一些疫苗可预防的疾病：第二部分。

IF 1.5

Pediatrics in review Pub Date : 2026-10-01 DOI: 10.1542/pir.2026-007211

Amanda Williams, Walter Dehority

引用次数: 0

22q11.2 Deletion Syndrome: A Comprehensive Review for Pediatricians From Diagnosis to Adult Care Transition. 22q11.2缺失综合征：儿科医生从诊断到成人护理过渡的综合综述。

IF 1.5

Pediatrics in review Pub Date : 2026-10-01 DOI: 10.1542/pir.2025-006952

Suzain Ali, Pranav Gupta

{"title":"22q11.2 Deletion Syndrome: A Comprehensive Review for Pediatricians From Diagnosis to Adult Care Transition.","authors":"Suzain Ali, Pranav Gupta","doi":"10.1542/pir.2025-006952","DOIUrl":"https://doi.org/10.1542/pir.2025-006952","url":null,"abstract":"Affecting ~1 in 4000 to 6000 live births, 22q11.2 deletion syndrome (22q11.2DS) is the most common chromosomal microdeletion syndrome. It results from a 1.5 to 3 Mb heterozygous deletion at chromosome 22q11.2 and is associated with a broad spectrum of clinical manifestations, including cardiac defects, palatal abnormalities, thymic hypoplasia, developmental delays, and neuropsychiatric symptoms. Multiple techniques such as chromosomal microarray and sequencing techniques such as fluorescence in situ hybridization help in the diagnosis of 22q11.2DS. A multidisciplinary approach to management is required, involving cardiology, immunology, endocrinology, speech therapy, psychiatry, and genetics. Surveillance should include monitoring for immunodeficiency, hypocalcemia, thyroid dysfunction, hematologic complications, and psychiatric illness. Genetic counselling and prenatal testing are crucial components in guiding families and informing reproductive decision-making. Additionally, structured transition of care programs should be employed to ensure continued care into adulthood. Although 22q11.2DS has gained significant recognition in the past decades, educational gaps still persist for pediatricians, especially regarding when to suspect, genetic testing, and coordination of care. This review aims to provide insights into the epidemiology, pathogenesis, system-based clinical features, diagnosis, management, and surveillance of 22q11.2DS, highlighting practical strategies that can be employed by pediatricians to improve early detection and optimize long-term outcomes.","PeriodicalId":20007,"journal":{"name":"Pediatrics in review","volume":"47 10","pages":"581-591"},"PeriodicalIF":1.5,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149113582","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Uncommon Causes of Jaundice in a 16-Year-Old Girl. 16岁女孩黄疸的不常见原因。

IF 1.5

Pediatrics in review Pub Date : 2026-10-01 DOI: 10.1542/pir.2025-007010

Anna H Bauer, Deepthi Rao, Charles B Chen

引用次数: 0

In Brief: Diaper Psoriasis. 简而言之：尿布牛皮癣。

IF 1.5

Pediatrics in review Pub Date : 2026-10-01 DOI: 10.1542/pir.2025-007074

Stephanie Am Satchell, Abigail M Marmito

引用次数: 0

Fever, Rash, Headache, and Altered Mental Status in an 11-Year-Old Boy. 11岁男童发热、皮疹、头痛及精神状态改变。

IF 1.5

Pediatrics in review Pub Date : 2026-10-01 DOI: 10.1542/pir.2025-007121

Sydney R Karre, Avinash K Shetty

引用次数: 0

Skin Lesion in a Child. 儿童皮肤病变。

IF 1.5

Pediatrics in review Pub Date : 2026-10-01 DOI: 10.1542/pir.2025-007116

Prachi Kothari, Anne Grifo, Kaitlin J Devine

引用次数: 0

Retinoblastoma for the Primary Care Pediatrician. 视网膜母细胞瘤的初级保健儿科医生。

IF 1.5

Pediatrics in review Pub Date : 2026-10-01 DOI: 10.1542/pir.2025-006996

Emily Liao, Chandan Lakhiani

引用次数: 0

12-Month-Old Presenting With Stridor to a Pediatric Emergency Department. 12个月大的儿童急诊科出现喘鸣。

IF 1.5

Pediatrics in review Pub Date : 2026-10-01 DOI: 10.1542/pir.2025-007107

Holly C Harper, Corrie E Roehm, Victoria S Gregg

引用次数: 0

The Pediatric Opioid Overdose and Addiction Crisis. 儿童阿片类药物过量和成瘾危机。

IF 1.5

Pediatrics in review Pub Date : 2026-10-01 DOI: 10.1542/pir.2025-006921

Adam Kronish, Scott E Hadland, Jessica B Calihan

引用次数: 0

Post Intensive Care Syndrome in Pediatrics-What the General Pediatrician Needs to Know About Life After Critical Illness. 儿科重症监护后综合征——普通儿科医生需要了解的重症后生活。

IF 1.5

Pediatrics in review Pub Date : 2026-10-01 DOI: 10.1542/pir.2024-006723

Chetna K Pande, Sarah Risen, Jessica M LaRosa, Sapna R Kudchadkar

{"title":"Post Intensive Care Syndrome in Pediatrics-What the General Pediatrician Needs to Know About Life After Critical Illness.","authors":"Chetna K Pande, Sarah Risen, Jessica M LaRosa, Sapna R Kudchadkar","doi":"10.1542/pir.2024-006723","DOIUrl":"https://doi.org/10.1542/pir.2024-006723","url":null,"abstract":"As mortality from pediatric critical illness has declined, post intensive care syndrome in pediatrics (PICS-p) has emerged as a framework to describe the broad and often long-lasting morbidities experienced by survivors of pediatric critical illness. PICS-p encompasses new or worsening impairment in physical, cognitive, emotional, and social health that affect both the child and their family. The term PICS-p also acknowledges and reinforces the traumatic impact of the critical care on the child and family dyad. Given the growing population of pediatric survivors of critical illness and the limited availability of newly emerging, specialized post-critical care clinics, it is imperative that general pediatricians, providing the child's medical home, are equipped to diagnose and manage PICS-p in the outpatient setting. In this review, we summarize the prevalence, pathophysiology, clinical course, and impact of PICS-p on children and families. We also review preventive strategies that can be implemented in the PICU and conclude with practical guidance for general pediatricians caring for children after critical illness.","PeriodicalId":20007,"journal":{"name":"Pediatrics in review","volume":"47 10","pages":"557-567"},"PeriodicalIF":1.5,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149113598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0