Modern medical technology最新文献

{"title":"Gender determinism of the effect of placenta cryoextract on the hepatotropic effects of esomeprazole, clarithromycin and metronidazole in chronic liver damage","authors":"M. Chyzh, I. Koshurba, M. M. Marchenko, F. Hladkykh, I. Belochkina","doi":"10.34287/mmt.1(56).2023.9","DOIUrl":"https://doi.org/10.34287/mmt.1(56).2023.9","url":null,"abstract":"Current regimens for the eradication of Helicobacter pylori infection include bismuth drugs, proton pump inhibitors, and a combination of 2–3 antibacterial drugs. Uncontrolled use of antibacterial agents as part of eradication schemes increases the risk of developing their unwanted drug reactions, in particular, hepatotoxicity. As a means with potentially hepatoprotective activity, our attention was drawn to placental cryoextract. \u0000The purpose of the study. To characterize the gender aspects of the hepatotropic action of placenta cryoextract in tetrachloromethane hepatitis with background ethanol-induced cirrhosis and liver damage by antiulcer agents. \u0000Materials and methods. Research was conducted on 112 male and female rats. Tetrachloromethane hepatitis with background ethanol-induced liver cirrhosis was reproduced by injecting an oil solution of CCl4 in combination with a 5.0% ethanol solution for 45 days. Modulation of the content of sex hormones was achieved by surgical ovariectomy or testectomy. \u0000Results and discussion. Administration of esomeprazole, clarithromycin, and metronidazole in chronic liver damage in animals without changes in hormonal status led to a statistically significant (p=0.01) 27.6% increase in the level of bilirubin in homogenates of liver tissues in female rats (78.7±4.5 mmol/l) than in males. The greatest decrease in the content of bilirubin (41.7%, p<0.001) with the use of cryoextract of the placenta was noted in castrated female rats with simulated tetrachlormethone hepatitis with background ethanol-induced cirrhosis of the liver, which were injected with antiulcer agents. \u0000Conclusions. Administration of cryoextract of the placenta has a pronounced hepatoprotective effect in animals of both sexes. In male rats with no change in hormonal status with simulated liver injury and the administration of antiulcer drugs, placenta cryoextract therapy was more effective than in female rats, as indicated by a more than 1.6-fold decrease in the content of bilirubin in the liver homogenates of male rats (43.1%, p<0.001) than in females (27.4%, p<0.01).","PeriodicalId":199868,"journal":{"name":"Modern medical technology","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127519298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"THE ALGORITHM FOR THE TREATMENT OF PATIENTS WITH TREATMENT-RESISTANT HYPERTENSION AT THE OUTPATIENT STAGE","authors":"O. Kulbachuk, E. Sid, O. Soloviov, A. Piskun","doi":"10.34287/mmt.1(56).2023.11","DOIUrl":"https://doi.org/10.34287/mmt.1(56).2023.11","url":null,"abstract":"Every year in the world, arterial hypertension is the cause of death in about 9 million cases. Blood pressure control in patients has not yet reached the appropriate level, and the percentage of resistant arterial hypertension remains high. According to the definition of the American Heart Association, those patients whose condition requires taking four or more drugs to control blood pressure should be considered resistant to treatment. It should be understood that uncontrolled hypertension is not synonymous with RAH. The presence of RAH significantly increases the risk of cardiovascular complications, contributes to serious damage to target organs. Preliminary diagnosis of RAH definitely requires the exclusion of secondary hypertension, which is a rather heterogeneous group of diseases that is poorly recognized. \u0000The goal of the work. To acquaint general practice - family medicine doctors with the algorithm of treatment of patients with resistant arterial hypertension at the ambulatory stage. \u0000Treatment of patients with RAH should be carried out in stages, with increased therapy, using the most simplified scheme of taking drugs. Today, the combination of ACEI (perindopril), BCC (amlodipine) and diuretic (indapamide) is considered as the most optimal triple combination of antihypertensive drugs. Medicines containing three antihypertensive drugs in one tablet are offered precisely for RAH patients. \u0000Conclusions. The implementation of the algorithm for the examination of patients with RAH, recommendations for changing their lifestyle and a step-by-step therapy plan allow improving the control of blood pressure. Treatment of patients with RAH should include optimization of dosages and the appointment of rational combinations of antihypertensive drugs in order to enhance synergistic effects. Optimization of pharmacotherapy by prescribing drugs with fixed combinations can improve control of drug administration. The fixed combination of amlodipine-indapamide-perindopril may have the important advantage of increasing treatment adherence due to the principle of \"one pill per day\".","PeriodicalId":199868,"journal":{"name":"Modern medical technology","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116571329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dermatoplasty for decompensated forms of varicose veins and post-thrombotic syndrome","authors":"V. I. Rusin, F. M. Pavuk, I. Kovalchuk, O. A. Nosenko","doi":"10.34287/mmt.1(56).2023.8","DOIUrl":"https://doi.org/10.34287/mmt.1(56).2023.8","url":null,"abstract":"Objective(s). In order to improve the results of the treatment of the decompensated form of varicose veins and post-thrombotic syndrome, taking into account the angiosomal theory and using VAC and Magott therapy of the recipient woundof the trophic ulcer, evaluate different methods of dermatoplasty depending on the depth and area of the lesion. \u0000Methods. In the surgical clinic of the regional hospital named after A. Novak, 174 patients with chronic venous insufficiency (CVI) in the stage of lecompensation were under our observation. According to the etiology of the disease, there were 76 patients with varicose desease (VD) (group I), 98 patients with PTS (group II), while 27 patients with PTS had trophic ulcers on both lower extremities. With a trophic ulcer (TU) diameter of up to 10 cm in the I group of patients, 42.1% had the depth of the lesion of the IIst, and in the patients of the IIa group, the depth of the lesion was the IIIrd. was observed in 51.4% of cases. In the 1st group (76) patients, TU was cleaned with the help of VAC therapy in 32 patients, Magott therapy was used in 18 patients. TcpO2 was measured in the angiosomes of the anterior tibial artery (APA), posterior tibial artery (PTA), and peroneal artery (PA), as the corresponding arteries participate in the perfusion of the corresponding skin-muscle flaps \u0000Results. Rejection (lysis) of the graft was observed in 5 (6.6%) patients of the 1st group, and only in patients with dermatoplasty using the vintage method. Graft lysis was observed in 4 (5.6%) patients of the IIa group, in two with the vintage method and in two with split graft transplantation. In the IIb group (both limbs affected), partial lysis of the transplanted perforated split graft was observed in three limbs (6%). No complications were observed when the tissue complex was transplanted freely. \u0000Conclusions. Free flaps are units of tissue that can be transplanted from the donor site to the recipient wound while maintaining its blood supply. Pieces can be classified by the type of blood supply, their tissue composition, the method of transplantation, or the orientation of the vessels. The concept of angiosomes and venosomes explains the blood supply to the recipient wound necessary for the viability of the flap. Various monitoring methods are used to monitor patients after surgery, including assessment of physiological parameters and auxiliary methods (dopplerography, transcutaneous and epidermal oximetry). Factors affecting the viability of transplants after surgery include: thorough surgical intervention, adequate immobilization after surgery, prevention of infection, and adequate vascularization of the recipient wound.","PeriodicalId":199868,"journal":{"name":"Modern medical technology","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123004089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"THROMBECTOMY IN PATIENTS WITH THROMBOSIS OF ARTERIO-VENOUS FISTULA: CASE SERIES","authors":"","doi":"10.34287/mmt.1(56).2023.3","DOIUrl":"https://doi.org/10.34287/mmt.1(56).2023.3","url":null,"abstract":"Introduction. Thanks to the use of renal replacement therapy at the current stage of medical development, complete medical and social rehabilitation of patients with end-stage chronic renal failure is possible. The key to effective programmed hemodialysis is the formation of adequate permanent vascular access. Ensuring the optimal use and functioning of permanent vascular access is a multidisciplinary challenge. Currently, none of the known options for permanent vascular access is ideal, but a native arteriovenous fistula meets the requirements to a greater extent. Complications from vascular access for hemodialysis remain relevant for their solution today. The most common complication of vascular access is thrombosis of an arteriovenous fistula. For patients with chronic renal failure who are on programmed hemodialysis, thrombosis of vascular access is a great danger, which ultimately can lead to the impossibility of further hemodialysis and is the main reason for hospitalization and high mortality of this contingent of patients and needs an urgent solution. \u0000Clinical cases. 17 patients underwent thrombectomy from the subcutaneous \"fistula\". vein of the upper extremity. The age of the patients was 49.0 (44.0-61.0) years. By gender, the studied patients were distributed as follows: women - 9 (53%), men - 8 (47%). Among 17 (100%) operated patients, 12 (71%) had late thrombosis, 5 (29%) had early thrombosis of arteriovenous fistula,. Of 5 (100%) patients with early thrombosis of arteriovenous fistula, thrombectomy was effective in 2 (40%) patients (p=0.038). On the other hand, in 12 (100%) patients with late thrombosis of arteriovenous fistula, thrombectomy was successful in only 4 (33%) cases. \u0000Discussion. The cause of thrombosis of any vascular anastomosis is primarily hyperplasia of the neointima due to the proliferation of smooth muscle cells of the vascular wall. This circumstance leads to the formation of stenosis of the anastomosis, and as soon as the stenosis values become hemodynamically significant (> 50% of the lumen of the vessel), the risk of developing thrombosis increases by more than 50%. Thrombectomy alone is insufficient to restore patency of the permanent vascular access in the long term, as flow-limiting stenosis is present in more than 85% of cases. \u0000Conclusions. Neointimal hyperplasia is the main cause of progressive stenosis of arteriovenous fistula and subsequent thrombosis. Thrombectomy is indicated for thrombosis of arteriovenous fistula in the early postoperative period (up to 30 days after arteriovenous fistula formation). Thrombectomy alone is not enough to restore the patency of the permanent vascular access in the long term, and the final treatment requires its reconstruction at an early stage or the creation of a new arteriovenous fistula.","PeriodicalId":199868,"journal":{"name":"Modern medical technology","volume":"38 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126601832","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Peculiarities of the course of the wound process in the treatment of acute paraproctitis in patients with type 2 diabetes","authors":"M. Milica, V. V. Soldusova, M. D. Postolenko, K. Milica, S. Chobey","doi":"10.34287/mmt.1(56).2023.4","DOIUrl":"https://doi.org/10.34287/mmt.1(56).2023.4","url":null,"abstract":"Objective. The purpose of the study is to reveal the features of the course of the wound process in patients with acute paraproctitis against the background of diabetes. \u0000Methods. An analysis of the results of treatment of acute parаproctitis against the background of diabetes in 328 patients over the past 5 years was carried out. \u0000Results. It was found that these patients are define by extensive tissue damage in area and the predominance of gram-negative bacteria in mixed aerobic flora, the addition of anaerobic flora is the cause of the spread of the purulent process and deep destruction of tissues. The synergism of the aerobic-anaerobic flora in combination with the pathogenetic factors of diabetes contribute to a severe and prolonged course of the inflammatory process, as evidenced by the preservation of a high index of intoxication until the 14th day. \u0000Conclusions. The criteria for choosing the method of operation are based on the localization of the abscess and the main purulent course, its relationship to the elements of the external anal sphincter, the nature of the scarring process in the area of internal diversion and the function of the closing apparatus of the rectum.","PeriodicalId":199868,"journal":{"name":"Modern medical technology","volume":"62 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124382827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Chronostructure and circadian rhythms of the parameters of the coagulation system and neurohumoral regulatory systems determining diurnal profile of blood pressure","authors":"","doi":"10.34287/mmt.1(56).2023.12","DOIUrl":"https://doi.org/10.34287/mmt.1(56).2023.12","url":null,"abstract":"The article is devoted to circadian rhythms of parameters of the hemostatic systems and humoral vasoactive factors determining diurnal profile of blood pressure. Researches indicate the presence of circadian rhythms of activity of autonomic nervous system and renin-angiotensin-aldosterone system in healthy human. Plasma catecholamines maximal activity is observed during the daytime, minimal one at night. Plasma renin activity and aldosterone concentration gradually decreases during the day, reaching its minimum at 4 p.m., followed by increase overnight to a peak at 8 a.m. Angiotensin-converting enzyme diurnal pattern is characterized by monophasic curve with maximal activity in the evening and minimum at night. Physiological features of hemostasis chronobiological characteristics in patients with coronary heart disease are present. All indexes of progressing coagulation and anticoagulation blood system has shown pronounced expressive shift of hypercoagulations in patients in the evening and at night. Fluctuations of insulin and glucose levels during 24 hours are also subject to circadian rhythm, i.e. maximal concentration is observed during the daytime, minimal one at night. Such diurnal rhythms are characteristic for patients without complicated arterial hypertension. However, circadian rhythms disturbances of humoral factors may further violate the circadian profile of blood pressure. It is pointed out that chronotherapy promote further development of the principle of individual treating approach.","PeriodicalId":199868,"journal":{"name":"Modern medical technology","volume":"184 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133676892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reasons for unsatisfactory results of treatment of destructive forms of erysipelas","authors":"S. D. Shapoval","doi":"10.34287/mmt.1(56).2023.5","DOIUrl":"https://doi.org/10.34287/mmt.1(56).2023.5","url":null,"abstract":"Goal. Find out the cause of unsatisfactory treatment outcomes in patients with destructive forms of erysipelas. \u0000Materials and methods. Retrospectively and prospectively analyzed 284 case histories of patients who were hospitalized in the center of purulent - septic surgery KNP \"City Hospital G3\" Zaporizhzhia for the period 2016-2022. \u0000Results. It was found that most often the local focus was localized on the upper and lower extremities. The most common clinical manifestations of intoxication in bullous and phlegmonous forms of erysipelas were: general weakness, hyperthermia, muscle pain. In the necrotic form of erysipelas, patients showed signs of severe intoxication with nausea, vomiting and confusion. In the complex treatment of patients with erysipelas, the main place belongs to the early surgical treatment of the area of ​​the pathological process and antibiotic therapy (ABT). \u0000Conclusions. Radical surgery and timely targeted ABT are key elements of success in the treatment of surgical forms of erysipelas and are not subject to revision. The main causes of unsatisfactory consequences in patients with erysipelas are: late referral of patients to the hospital, aggravation of the disease at the time of hospitalization by septic shock and multiple organ failure, severe decompensated comorbidities.","PeriodicalId":199868,"journal":{"name":"Modern medical technology","volume":"56 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134269071","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of oxidative proteins modification level in infertile males ejaculate secondary to toxocara invasion","authors":"","doi":"10.34287/mmt.1(56).2023.1","DOIUrl":"https://doi.org/10.34287/mmt.1(56).2023.1","url":null,"abstract":"Our research was aimed at revealing level of proteins oxidative proteins modification in ejaculate homogenate for patients with reproductive damages secondary to toxocara invasion. \u0000Materials and methods. The article contains the data of researching proteins oxidative modification in ejaculate and values for congenital immunity cells factors in 89 men being divided into five groups depending on spermatozoa DNA values and presence or lack of toxocara invasion. \u0000The results. According to the data obtained it has been established that increasing OPM values with different intensity in ejaculate depending on peculiarities of damaging factor were being observed. Incomplete phagocytosis of the neutrophil link was determined, but only in the 3rd and 4th groups was noted a simultaneous decrease in HSTsp and HSTst, which indicated a deep damage to the bactericidal system of phagocytes, which also, apparently, occurs due to inhibition of the metabolism of immunocompetent cells and their bioenergetic resources by toxic products of life activity of helminths. It was in the groups with the most pronounced oxidative stress that DNA fragmentation of spermatozoa was also observed, which, in turn, was combined with the more severe forms of pathozoospermia in the 4th and 5th groups we discovered earlier. \u0000Conclusions. Thus, insignificant OPM increasing in patients of the third and fourth groups (with antibodies against toxocara) is connected with defense formed by helminths against damaging factors, such as OPM and phagocytosis, that is confirmed by incomplete phagocytosis secondary to functional and metabolic reserve deficiency. High OPM values in patients of second and fifth groups indicate only influence of environment (industrial pollutants in air), many of them can be themselves booster to develop and maintain OPM high values.","PeriodicalId":199868,"journal":{"name":"Modern medical technology","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117075703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Characteristics of the antiulcerogenic activity of cryopreserved placenta extract in acute and chronic lesions of the stomach","authors":"F. Hladkykh, I. Koshurba, M. Chyzh","doi":"10.34287/mmt.1(56).2023.10","DOIUrl":"https://doi.org/10.34287/mmt.1(56).2023.10","url":null,"abstract":"To date, Ukraine has registered about 5 million patients with ulcer disease, and the market of drugs with proven anti-ulcer activity exceeds 500 names, but the problem of effective therapy is far from being solved. Cryoextract of the placenta attracted our attention as a new domestic biotechnological anti-ulcer agent. \u0000The purpose of the study. To characterize the antiulcer activity of cryoextract of human placenta in acute and chronic ulcerogenesis. \u0000Materials and methods. Studies of antiulcer activity were carried out on 56 male rats weighing 200–220 g in two stages: on the model of acute serotonin ulcerogenesis (28 rats) under the therapeutic and prophylactic regimen of placenta cryoextract and on the model of chronic acetic acid damage to the stomach (28 rats) under the therapeutic regimen application of the specified cryoextract. \u0000Results and discussion. The study showed that the therapeutic and prophylactic injection of the cryoextract of the placenta shows a pronounced antiulcer activity in the model of serotonin-induced gastric damage, which was indicated by a decrease in the ulcer index by 13.7 times compared to a similar indicator in the group of untreated animals and was 0.3 and 4, respectively. 1. Hemorrhagic lesions of the gastric mucosa occurred twice as often against the background of placenta cryoextract administration, respectively, against the background of esomeprazole administration – in 57.1% of rats, and against the background of placenta cryoextract administration – in 28.6% of rats. It was established that the investigated cryoextract has a cytoprotective effect on the mucous membrane of the stomach against the background of acetic acid damage. This was indicated by a statistically significant (p<0.05) decrease in the ulcer index by 30.0% compared to the indicators of untreated animals. \u0000Conclusions. It was established that the cryoextract of the human placenta has pronounced antiulcer activity both in acute and chronic experimental ulcerogenesis, which was indicated by a statistically significant decrease in erosions and ulcers of the gastric mucosa.","PeriodicalId":199868,"journal":{"name":"Modern medical technology","volume":"375 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115992900","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"TREATMENT OF PURULOUS-INFLAMMATORY COMPLICATIONS OF INJURIES AND DISEASES OF PELVIC BONES","authors":"","doi":"10.34287/mmt.1(56).2023.2","DOIUrl":"https://doi.org/10.34287/mmt.1(56).2023.2","url":null,"abstract":"Summary. Purulent-inflammatory complications of fractures of pelvic bones represent up to currently one of the most difficult and little-studied sections of traumatology. Complexity anatomical structure and topographic relations of the pelvic region, deep location a significant part of the bones under the muscle mass create objective difficulties for surgical treatment of bone damage and later in the diagnosis of purulent processes. Osteomyelitis of the pelvis is accompanied by high mortality and is from 2.5 to 52% as in acute and in the chronic stage of the disease. \u0000Purpose: by analyzing clinical mistakes and the possibility of purulent-inflammatory complications during operative treatment and postoperative management of patients with fractures bones of the pelvis, as well as to determine methods of diagnosis, treatment and ways of prevention traumatic sacroiliitis. \u0000Materials and methods. In the period from 2017 to 2022 in the bone-purulent surgery department of Zaporizhzhia city clinical hospital №9 treated 9 patients with purulent processes in of the pelvic region, 6 (66.3%) of them were men, and 3 (33.4%) were women. With postoperative osteomyelitis, which occurred after osteosynthesis with plates of multiple pelvic bone fractures, 4 (44.5%) patients were treated. Conservative therapy with sacroiliitis, the cause of which was abortion, received by 2 (22.2%) women, 1 (11.1%) patient suffered from right-sided sacroiliitis since childhood and repeatedly operated, and 2 (22.2%) men were treated with cause of sacroiliitis, which occurred after slaughter of the sacroiliac joint area. \u0000Results. All patients who were treated in the bone-purulent surgery department for purulent-inflammatory processes of pelvic bones, recovered and were discharged for outpatient treatment. While treatment in the ward, patients received complex treatment, which included conservative therapy and surgical intervention. Despite the introduction of modern methods of treatment of osteomyelitis of the pelvis, a trend of steady growth in the number is noted exits of patients with disabilities, which is confirmed by world statistics. \u0000Conclusions. Lack of hard fixation of bone fragments by implants increases the risk of purulent complications in the postoperative period. Use of additional diagnostic methods and complex treatment, which includes radical purulent sanitation foci, creation of favorable conditions for tissue regeneration, prevention of relapses suppuration, targeted antibacterial therapy, correction of homeostasis indicators and increases the protective forces of the body during purulent processes of the bones and joints of the pelvis achieving positive results in 80.2% of patients.","PeriodicalId":199868,"journal":{"name":"Modern medical technology","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124478664","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}