Shutaro Masuda, Yuko Fujita, Tomohiro Takeshima, Mai Fujimoto
{"title":"Impact of gender and physical differences on the development of oral functions in children aged 6–17 years: A cross-sectional study","authors":"Shutaro Masuda, Yuko Fujita, Tomohiro Takeshima, Mai Fujimoto","doi":"10.1016/j.pdj.2023.09.002","DOIUrl":"10.1016/j.pdj.2023.09.002","url":null,"abstract":"<div><h3>Objective</h3><p>This study aimed to establish the age at which oral function development completes in males and females, and to determine if obesity contributes to underdevelopment of oral function.</p></div><div><h3>Materials and Methods</h3><p>The study included 241 participants, including 121 males and 120 females aged 6 to 17 years. Following anthropometry and oral examination, maximum occlusal force, lip-closing strength, maximum tongue pressure, and masticatory performance were measured in all participants. The Rohrer Index and body mass index (BMI) were calculated using height and weight measurements, and these scores were grouped into underweight/severely underweight, normal weight, and overweight/obese categories.</p></div><div><h3>Results</h3><p>In males, maximum occlusal force, lip-closing strength, maximum tongue pressure, and masticatory performance increased with age. In females, maximum occlusal force, maximum tongue pressure, and masticatory performance peaked during the teenage years. Masticatory performance in the overweight/obese male group was significantly lower than in the normal weight group (<em>p</em> < 0.05). In females, maximum occlusal force in the underweight/severely underweight group and maximum tongue pressure in the overweight/obese group were significantly lower than in the normal weight group (both, p < 0.05).</p></div><div><h3>Conclusion</h3><p>Growth patterns of each oral function differ considerably between males and females. Oral functions in females typically reached their peak earlier than in males, with most functions peaking during the teenage years. Overweight/obesity contribute to the underdevelopment of oral functions in both genders. Underweight may also hinder oral function development in females.</p></div>","PeriodicalId":19977,"journal":{"name":"Pediatric Dental Journal","volume":"33 3","pages":"Pages 182-191"},"PeriodicalIF":0.8,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0917239423000435/pdfft?md5=ba71ba8804f257d9bdc438079bd7a25c&pid=1-s2.0-S0917239423000435-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135605343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Dens invaginatus of fourteen teeth in a pediatric patient","authors":"Momoko Usuda , Tatsuya Akitomo , Mariko Kametani, Satoru Kusaka, Chieko Mitsuhata, Ryota Nomura","doi":"10.1016/j.pdj.2023.10.001","DOIUrl":"10.1016/j.pdj.2023.10.001","url":null,"abstract":"<div><h3>Background</h3><p>Dens invaginatus<span> is a dental anomaly in which the enamel and dentin are deeply enfolded in the pulp cavity.</span></p></div><div><h3>Case presentation</h3><p>A 12-year-and-8-month-old Japanese male was diagnosed with 14 permanent teeth with dens invaginatus. We covered the premolars with glass-ionomer liner, and the pain gradually resolved. Eight months later, periapical radiographs revealed that their roots had developed, confirming the survival of the pulp.</p></div><div><h3>Conclusion</h3><p>The patient had not received regular check-ups, and dens invaginatus was diagnosed for the first time when pain occurred. This report highlights the importance of regular dental check-ups.</p></div>","PeriodicalId":19977,"journal":{"name":"Pediatric Dental Journal","volume":"33 3","pages":"Pages 240-245"},"PeriodicalIF":0.8,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135809432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Survey of primary tooth eruption status of down syndrome in Japan: Comparison with the Japanese National Survey of Dental Diseases","authors":"Kazutaka Noda , Shinhachi Hanaoka , Masahiro Watanabe , Kazumi Kubota , Koji Yamauchi , Kaoru Kobayashi , Hirokatsu Harasawa , Risa Ikeda , Tomoya Yamahata , Takahiro Funatsu , Masakazu Ikeda , Yoshiharu Mukai , Shouji Hironaka","doi":"10.1016/j.pdj.2023.07.001","DOIUrl":"10.1016/j.pdj.2023.07.001","url":null,"abstract":"<div><h3>Introduction</h3><p>Down syndrome (DS) can cause irregular dental eruption patterns and hypodontia. However, data on primary tooth eruption with DS in Japan are insufficient. Therefore, this study aimed to conduct a questionnaire survey to predict dental abnormalities in DS based on tooth eruption status.</p></div><div><h3>Methods</h3><p>A questionnaire survey on the age, sex, number of present teeth, and dental formula of patients with DS was conducted at facilities providing dental care for the disabled in Japan, and the results were compared with those of the Survey of Dental Diseases used as for the control survey.</p></div><div><h3>Results</h3><p>A total of 3656 valid responses were received. This study was analyzed according to the age group of the Survey of Dental Diseases. At 1–14 years old, the mean number of primary teeth per patient was the highest at 4 years old (19.3 teeth). The largest difference from the control survey was at 1 year old, and the difference decreased with age until 4 years. At 3–5 years old, the rate of individual primary tooth eruptions was 14.2% lower for the mandibular primary lateral incisors than that in the control survey. At 15 years old or older, the percentage of people who had persistence of primary teeth was 19.2%. The second primary molars were the most common persistent primary teeth.</p></div><div><h3>Conclusion</h3><p>DS is characterized by delayed tooth eruption, high incidence of missing teeth, particularly the mandibular primary lateral incisors, and persistence of primary teeth. These findings indicate the importance of developmental support and oral management.</p></div>","PeriodicalId":19977,"journal":{"name":"Pediatric Dental Journal","volume":"33 3","pages":"Pages 167-174"},"PeriodicalIF":0.8,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S091723942300040X/pdfft?md5=6431715afb7103dd0cf04567ca54ce5c&pid=1-s2.0-S091723942300040X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"55222606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shunsuke Kako , Masako Tabuchi , Yuki Aoki , Takuma Sato , Hiroyuki Nawa , Ken Miyazawa
{"title":"A case of dilaceration of a permanent tooth resulting from trauma to the preceding primary tooth","authors":"Shunsuke Kako , Masako Tabuchi , Yuki Aoki , Takuma Sato , Hiroyuki Nawa , Ken Miyazawa","doi":"10.1016/j.pdj.2023.09.003","DOIUrl":"10.1016/j.pdj.2023.09.003","url":null,"abstract":"<div><h3>Background</h3><p><span>Trauma to primary teeth can cause </span>dilaceration of permanent teeth.</p></div><div><h3>Case presentation</h3><p>A boy aged 14 years 6 months at initial presentation had a history of dental trauma at age 4 years. Radiography revealed significant dilaceration and impaction of the maxillary left central incisor, and preservation of the tooth was judged to be infeasible. The necessity of extracting the maxillary left central incisor was supported by examination using the latest digital technology.</p></div><div><h3>Conclusion</h3><p><span>Digital technology can play an important role in deciding treatment strategies for an </span>impacted tooth with dilaceration.</p></div>","PeriodicalId":19977,"journal":{"name":"Pediatric Dental Journal","volume":"33 3","pages":"Pages 228-239"},"PeriodicalIF":0.8,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135761628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Conservative management of Mycoplasma pneumoniae-induced Stevens Johnson syndrome in a paediatric patient: A case report","authors":"Amanda Lin , Neeta Prabhu","doi":"10.1016/j.pdj.2023.10.003","DOIUrl":"10.1016/j.pdj.2023.10.003","url":null,"abstract":"<div><h3>Background</h3><p>Stevens-Johnson Syndrome (SJS) is a rare and potentially life-threatening condition causing blistering and epithelial sloughing of the skin and mucous membranes. It is most commonly caused by infective pathogens or drugs.</p></div><div><h3>Case presentation</h3><p>A 14-year-old male patient presented with reduced oral intake following painful oral ulcerations secondary to a diagnosis of <em>Mycoplasma pneumoniae</em>-induced SJS. Treatment involved intravenous fluids, antimicrobials and analgesia, alongside atraumatic conservative management of the oral mucosa.</p></div><div><h3>Conclusion</h3><p>While there are no evidence-based treatment guidelines for <em>Mycoplasma pneumoniae</em>-induced SJS, conservative care is the cornerstone of management of paediatric presentations.</p></div>","PeriodicalId":19977,"journal":{"name":"Pediatric Dental Journal","volume":"34 1","pages":"Pages 46-48"},"PeriodicalIF":0.8,"publicationDate":"2023-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0917239423000472/pdfft?md5=da6b20581357a3c54216f4340302602a&pid=1-s2.0-S0917239423000472-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136127708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Chantal Kerbage , Anthony T. Macari , Anthony Kerbage , Nada Chedid
{"title":"Comparison of oral health characteristics in pediatric cancer and cancer free patients: A multicenter study","authors":"Chantal Kerbage , Anthony T. Macari , Anthony Kerbage , Nada Chedid","doi":"10.1016/j.pdj.2023.05.001","DOIUrl":"10.1016/j.pdj.2023.05.001","url":null,"abstract":"<div><h3>Introduction</h3><p>Comparing oral health of cancer to non-cancer children proves that cancer and its treatment can cause oral complications.</p></div><div><h3>Design</h3><p>Two groups of children, 50 treated for cancer, and 51 cancer-free, at two different centers, signed informed consent<span> forms. Both the examination of teeth, oral functions and soft tissue with a questionnaire including the patients’ demographic characteristics, medical history, dietary and oral hygiene, and changes due to the oncologic treatment allowed gathering data.</span></p></div><div><h3>Results</h3><p>The two groups had no demographic nor socio-economic differences. Dietary habits were not significantly different. Daily brushing was more frequent in cancer-free (96.1%) versus sick (76%) children. Oral hygiene was poor (34%) or very poor (24%) in cancer patients and average for non-cancer subjects (68.6%). Cancer patients had more caries, without significant differences between groups. Gingiva<span><span> was healthy in 96.1% of non-cancer and 76% of cancer patients (p = 0.044). In cancer patients, intra-oral soft tissue lesions were aphtous ulcers (52.9%), </span>candidiasis<span> (23.5%), and herpes (17.6%). Xerostomia was significantly different (p = 0.001) between cancer (32%) and non-cancer subjects (3.9%). Chemotherapy alone is an independent predictor of poor oral health (HR 17.7, 95% CI [5.2–60.9], p < 0.001).</span></span></p></div><div><h3>Conclusion</h3><p>Cancer patients had poor oral health compared to non-cancer children, with insufficient knowledge concerning the relationship between oral and general health. Education programs, screenings and treatment at cancer centers may help reduce risks of complications.</p></div>","PeriodicalId":19977,"journal":{"name":"Pediatric Dental Journal","volume":"33 2","pages":"Pages 139-146"},"PeriodicalIF":0.8,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43361100","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Application of the salivary multi test in children with severe congenital neutropenia: A case report","authors":"Yuko Iwamoto , Nobuyuki Tatsukawa , Yasumasa Irie , Satoru Kusaka , Chieko Mitsuhata , Ryota Nomura","doi":"10.1016/j.pdj.2023.05.002","DOIUrl":"10.1016/j.pdj.2023.05.002","url":null,"abstract":"<div><h3>Background</h3><p>A Salivary Multi Test® (SMT®) was used in children with severe congenital neutropenia<span> who were admitted to the pediatrics department of our hospital.</span></p></div><div><h3>Case presentation</h3><p>SMT® was conducted on three patients with severe congenital neutropenia. Rod and segmented neutrophil counts in the peripheral blood showed fluctuations similar to those of the “leukocyte level” in SMT®.</p></div><div><h3>Conclusion</h3><p>SMT®, which uses saliva samples that are non-invasive and can be easily collected, may help manage systemic diseases.</p></div>","PeriodicalId":19977,"journal":{"name":"Pediatric Dental Journal","volume":"33 2","pages":"Pages 152-158"},"PeriodicalIF":0.8,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47162953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Concentrations of interleukin-32, interleukin −10, interleukin −6, and TNF-alfa are higher in saliva of children with early childhood caries","authors":"Ecem Gur , Sultan Keles , Ozge Cevik","doi":"10.1016/j.pdj.2023.03.005","DOIUrl":"10.1016/j.pdj.2023.03.005","url":null,"abstract":"<div><h3>Aim</h3><p>To investigate if the levels of interleukin-32 (IL-32), interleukin-10 (IL-10), interleukin-6 (IL-6), and tumor necrosis factor-alpha (TNF-α) in the saliva are associated with early childhood caries.</p></div><div><h3>Methods</h3><p>A total of 56 patients aged between 36 and 71 months with dental caries and without caries were included in this study. The patients’ caries status was evaluated according to the dmft and dmfs indices. IL-32, IL-10, IL-6, and TNF-α levels in the saliva samples of the patients were measured by ELISA.</p></div><div><h3>Results</h3><p>There were no statistically significant differences in the oral hygiene and nutritional habits, plaque index<span>, and gingival index values between the ECC and control groups evaluated in the study (p > 0.05). The ECC group's salivary IL-32, IL-10, IL-6, and TNF-α levels were statistically significantly higher than the control group (p < 0.001).</span></p></div><div><h3>Conclusion</h3><p>The high levels of IL-32, IL-10, IL-6, and TNF-α detected in the saliva of children with ECC reveal that these cytokines may play a potential role in ECC pathogenesis. Salivary levels of IL-32, IL-10, IL-6, and TNF-α are associated with early childhood caries in children.</p></div>","PeriodicalId":19977,"journal":{"name":"Pediatric Dental Journal","volume":"33 2","pages":"Pages 116-124"},"PeriodicalIF":0.8,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41898851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kifu Miyata , Yuta Chiba , Triana Marchelina , Saori Inada , Sae Oka , Kan Saito , Aya Yamada , Satoshi Fukumoto
{"title":"Single-cell RNA-sequence of dental epithelium reveals responsible genes of dental anomalies in human","authors":"Kifu Miyata , Yuta Chiba , Triana Marchelina , Saori Inada , Sae Oka , Kan Saito , Aya Yamada , Satoshi Fukumoto","doi":"10.1016/j.pdj.2023.03.004","DOIUrl":"10.1016/j.pdj.2023.03.004","url":null,"abstract":"<div><h3>Objectives</h3><p><span>Dental anomalies show various symptoms and some of them are accompanied with inherited </span>diseases. However, only a few of responsible genes of dental anomalies are identified. In this study, we aimed to establish a novel strategy for identification of responsible genes of dental anomalies using integration of single-cell RNA-sequence (scRNA-seq) and Online Mendelian Inheritance in Man (OMIM).</p></div><div><h3>Materials and methods</h3><p>Single cells were isolated from mandibular incisor of post-natal day (P) seven mice and scRNA-seq were performed. Top 20 differentially expressed genes between clusters were identified and used for further analyses. Inherited diseases of differentially expressed genes and their Clinical Synopsis were examined using OMIM.</p></div><div><h3>Results</h3><p><span>The prevalence of inherited disease was 43/80 genes (53.8%) and inherited diseases which associate with dental anomalies were 34/96 diseases (35.4%); 14.6% in enamel abnormality, 4.1% in dentin abnormality, and 16.7% in other abnormality. The prevalence of enamel abnormality was the highest in </span>ameloblast<span>, while that of other abnormality was high in non-ameloblast cell types. Chromosomal mapping of differentially expressed genes indicated that chromosome 4 has “hotspots” of dental anomalies-associated genes.</span></p></div><div><h3>Conclusion</h3><p>The differentially expressed genes in dental epithelial cells were responsible for inherited disease which shows dental anomalies. The strategy employed in this study will contribute to identify the responsible gene for dental anomalies.</p></div>","PeriodicalId":19977,"journal":{"name":"Pediatric Dental Journal","volume":"33 2","pages":"Pages 102-115"},"PeriodicalIF":0.8,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49063053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Evaluation of antibacterial efficacy of ultrasonic-activated and inactivated chlorhexidine (solution and gel) in infected root canals of primary anterior teeth","authors":"Rahaf Kharsa , Mohanad Laflouf , Taissir Albouni , Hasan Alzoubi","doi":"10.1016/j.pdj.2023.03.003","DOIUrl":"10.1016/j.pdj.2023.03.003","url":null,"abstract":"<div><h3>Objectives</h3><p>Sodium hypochlorite is not able to completely eliminate <span><em>Enterococcus faecalis</em></span><span><span> inside root canals. Therefore, this study aimed to evaluate chlorhexidine gel and solution in eliminating bacterial counts within infected root canals of primary </span>anterior teeth.</span></p></div><div><h3>Materials and methods</h3><p>This study included 75 primary anterior teeth in 27 healthy children and it was divided into five groups: Group 1: Chlorhexidine 2% solution, Group 2: Chlorhexidine 2% solution activated by ultrasonic, Group 3: Chlorhexidine 2% gel, Group 4: Chlorhexidine 2% gel activated by ultrasonic, and Group 5: Sodium hypochlorite solution 5.25%. The preliminary smear for bacterial study (S1) was taken before irrigation. The root canals were irrigated in a quantity of 7 ml using a 31-gauge irrigation needle, and irrigant activation was 2 cycles (20 s). The final smear for bacterial study (S2) was taken after irrigation.</p></div><div><h3>Results</h3><p>There were no statistically differences in the mean percentage change in the decimal logarithm of the anaerobic bacterial colony count, but statistically differences were found for aerobic bacteria. For aerobic bacteria: CHx 2% solution activated better than CHx 2% and NaOCl 5.25% solutions, CHx 2% gel better than CHx 2% solution, CHx 2% gel activated better than CHx 2% and NaOCl 5.25% solutions.</p></div><div><h3>Conclusion</h3><p><span>All irrigation solutions used are effective in eliminating bacterial counts in infected primary canals. Chlorhexidine (solution and gel) can be considered a good alternative to sodium hypochlorite in irrigation root canals of </span>primary teeth.</p></div>","PeriodicalId":19977,"journal":{"name":"Pediatric Dental Journal","volume":"33 2","pages":"Pages 93-101"},"PeriodicalIF":0.8,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48809333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}