Pancreatology最新文献

Clinical importance of suspicious for malignancy compared to positive for malignancy in peritoneal cytology for surgically resected pancreatic cancer. 胰腺癌手术切除后腹膜细胞学检查恶性肿瘤可疑与恶性肿瘤阳性的临床重要性。

IF 2.8 2区医学

Pancreatology Pub Date : 2025-05-24 DOI: 10.1016/j.pan.2025.05.006

Haruyoshi Tanaka, Kenichi Hirabayashi, Tsutomu Fujii, Nobuyuki Ohike, Makoto Ueno, Takahiro Mizui, Masaharu Ishida, Shinichi Egawa, Toru Furukawa, Yuichi Nagakawa, Takao Itoi, Hirohisa Kitagawa, Yohei Masugi, Masaji Tani, Noriyoshi Fukushima, Takashi Hatori, Yosuke Tajika, Sohei Satoi, Michiaki Unno, Yoshifumi Takeyama

{"title":"Clinical importance of suspicious for malignancy compared to positive for malignancy in peritoneal cytology for surgically resected pancreatic cancer.","authors":"Haruyoshi Tanaka, Kenichi Hirabayashi, Tsutomu Fujii, Nobuyuki Ohike, Makoto Ueno, Takahiro Mizui, Masaharu Ishida, Shinichi Egawa, Toru Furukawa, Yuichi Nagakawa, Takao Itoi, Hirohisa Kitagawa, Yohei Masugi, Masaji Tani, Noriyoshi Fukushima, Takashi Hatori, Yosuke Tajika, Sohei Satoi, Michiaki Unno, Yoshifumi Takeyama","doi":"10.1016/j.pan.2025.05.006","DOIUrl":"https://doi.org/10.1016/j.pan.2025.05.006","url":null,"abstract":"Background/objectives: Positive peritoneal cytology (Cy+) is considered a form of microscopic dissemination and a poor prognostic factor in resected pancreatic cancer (PC). However, the clinical implications of equivocal categories such as atypia of undetermined significance (AUS) and suspicious for malignancy (SFM) remain unclear.Methods: We retrospectively analyzed patients with PC who underwent surgery at 13 high-volume centers between January 2009 and December 2018. Inclusion criteria were: 1) cytology results of AUS, SFM, or malignant (MAL); 2) resectable (R) or borderline resectable (BR); 3) no other macroscopic metastases; and 4) no preoperative therapy.Results: A total of 239 cases were included (AUS: 58, SFM: 31, MAL: 150), with R/BR = 196/43. Survival curves for SFM closely resembled those for MAL but differed from AUS. Grouped analysis showed that SFM + MAL patients had significantly shorter median overall survival (OS) than AUS patients (19.6 vs. 28.0 months, HR 1.61, P < 0.01) and shorter recurrence-free survival (RFS: 8.0 vs. 12.7 months, HR 1.53, P = 0.01). This trend persisted in resectable cases (OS: 21.1 vs. 30.5 months, HR 1.74; RFS: 9.1 vs. 14.2 months, HR 1.57; all P < 0.01).Conclusions: The cytology of SFM in PC is associated with a prognosis comparable to that of MAL, suggesting the need for cautious clinical interpretation and potential reclassification.","PeriodicalId":19976,"journal":{"name":"Pancreatology","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144180025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impact of zinc deficiency on the prognosis of unresectable pancreatic cancer. 缺锌对不可切除胰腺癌预后的影响。

IF 2.8 2区医学

Pancreatology Pub Date : 2025-05-16 DOI: 10.1016/j.pan.2025.05.007

Yusuke Seiki, Kenji Ikezawa, Yugo Kai, Ryoji Takada, Masaki Kawabata, Hiroki Kishimoto, Kana Hosokawa, Ko Watsuji, Kazuhiro Kozumi, Makiko Urabe, Kaori Mukai, Tasuku Nakabori, Kazuyoshi Ohkawa

{"title":"Impact of zinc deficiency on the prognosis of unresectable pancreatic cancer.","authors":"Yusuke Seiki, Kenji Ikezawa, Yugo Kai, Ryoji Takada, Masaki Kawabata, Hiroki Kishimoto, Kana Hosokawa, Ko Watsuji, Kazuhiro Kozumi, Makiko Urabe, Kaori Mukai, Tasuku Nakabori, Kazuyoshi Ohkawa","doi":"10.1016/j.pan.2025.05.007","DOIUrl":"https://doi.org/10.1016/j.pan.2025.05.007","url":null,"abstract":"Background/objectives: Pancreatic cancer (PC) is an aggressive malignancy with a poor prognosis. Zinc deficiency (ZD) is prevalent among patients with cancer, especially those with PC, owing to factors such as malabsorption and systemic inflammation. Although ZD is associated with poor nutritional status and cancer cachexia, its impact on overall survival (OS) in unresectable PCs remains unclear. This study aimed to evaluate the prevalence of ZD in patients with unresectable PC and its influence on prognosis.Methods: A retrospective study was conducted on 272 patients with unresectable pancreatic cancer whose serum zinc levels measured before starting chemotherapy between April 2016 and March 2024. ZD was defined as serum zinc level below 60 μg/dL. Patient characteristics, nutritional indices (modified Glasgow prognostic score [mGPS], neutrophil-to-lymphocyte ratio [NLR], prognostic nutritional index [PNI], controlling nutritional status [CONUT] score), and survival outcomes were analyzed.Results: ZD was identified in 19.4 % of patients. Patients with ZD were significantly older and exhibited lower PNI, indicating poorer nutritional status. Regarding OS, univariate analysis showed that the ZD group had significantly lower survival rates than non-ZD group. Multivariate analysis revealed that ZD was an independent predictor of poor prognosis.Conclusions: This study demonstrates that ZD before chemotherapy is an independent prognostic factor in patients with unresectable PC undergoing chemotherapy. Considering its association with poor nutritional status, serum zinc levels may serve as a valuable prognostic biomarker. Further research is warranted to explore the potential therapeutic benefits of zinc supplementation therapy.","PeriodicalId":19976,"journal":{"name":"Pancreatology","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144132788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Risk factors of delayed gastric emptying after distal pancreatectomy: A comprehensive systematic review and meta-analysis. 远端胰腺切除术后胃排空延迟的危险因素：一项全面的系统回顾和荟萃分析。

IF 2.8 2区医学

Pancreatology Pub Date : 2025-05-16 DOI: 10.1016/j.pan.2025.05.009

Chengshuai Pang, Rui Cao, Xiaowen Gong, Chenyang Dong, Yuerong Xuan, Chaojie Liang

{"title":"Risk factors of delayed gastric emptying after distal pancreatectomy: A comprehensive systematic review and meta-analysis.","authors":"Chengshuai Pang, Rui Cao, Xiaowen Gong, Chenyang Dong, Yuerong Xuan, Chaojie Liang","doi":"10.1016/j.pan.2025.05.009","DOIUrl":"https://doi.org/10.1016/j.pan.2025.05.009","url":null,"abstract":"Background: Delayed gastric emptying (DGE) is a common complication after distal pancreatectomy (DP). However, its incidence and risk factors remain unclear. This meta-analysis aims to clarify the incidence and risk factors associated with DGE following DP.Methods: We conducted a systematic search of PubMed, EMBASE, Web of Science, and the Cochrane Library for studies on DGE after DP, covering publications up to July 4, 2024. Odds ratios (OR) and 95 % confidence intervals (95 %CI) were pooled using random-effects or fixed-effects models. And heterogeneity testing and bias assessment were conducted.Results: A total of 82 studies involving 35,248 patients were included. The pooled analysis showed an incidence of DGE after DP of approximately 5.0 %. Among seven non-surgical risk factors, benign lesions as a protective factor for DGE after DP,while age over 75 was identified as potential risk factor for DGE after DP. Of the 21 surgical-related risk factors, early drain removal and laparoscopic distal pancreatectomy (LDP) were linked to a lower incidence of DGE, while factors such as hemorrhage, multivisceral resection, postoperative pancreatic fistula (POPF), portal vein resection, postoperative abscess, and wound infection were identified as potential risk factors for DGE after DP.Conclusion: The incidence of DGE after DP is approximately 5.0 %. Risk factors include malignancy, open distal pancreatectomy (ODP), delayed drain removal, age over 75, hemorrhage, multivisceral resection, POPF, portal vein resection, postoperative abscess, and wound infection. This meta-analysis provides valuable insights for clinical practice, especially in improving the screening and management of high-risk patients. However, further large-scale, multicenter randomized controlled trials are needed to confirm these findings.","PeriodicalId":19976,"journal":{"name":"Pancreatology","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144132790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

SEER-based evaluation of lymph node yield as a prognostic indicator of cancer-specific survival in nonmetastatic pancreatic ductal adenocarcinoma. 基于seer的评估淋巴结产量作为非转移性胰腺导管腺癌癌症特异性生存的预后指标。

IF 2.8 2区医学

Pancreatology Pub Date : 2025-05-16 DOI: 10.1016/j.pan.2025.05.008

Hwee Leong Tan, Yun Zhao, Darren Weiquan Chua, Brian Kim Poh Goh, Ye Xin Koh

{"title":"SEER-based evaluation of lymph node yield as a prognostic indicator of cancer-specific survival in nonmetastatic pancreatic ductal adenocarcinoma.","authors":"Hwee Leong Tan, Yun Zhao, Darren Weiquan Chua, Brian Kim Poh Goh, Ye Xin Koh","doi":"10.1016/j.pan.2025.05.008","DOIUrl":"https://doi.org/10.1016/j.pan.2025.05.008","url":null,"abstract":"Background/objectives: Although the American Joint Committee on Cancer (AJCC) 8th edition recommends harvesting at least 12 lymph nodes for optimal staging in pancreatic ductal adenocarcinoma (PDAC), the precise lymph node yield (LNY) needed for accurate prognostication in different treatment settings remains unclear. This study aimed to identify subgroup-specific LNY cutoffs and evaluate their prognostic significance in nonmetastatic PDAC.Methods: We analyzed 5609 patients with nonmetastatic PDAC from the Surveillance, Epidemiology, and End Results (SEER) database undergoing pancreatectomy. Patients were categorized by nodal status (N0 vs. N+) and receipt of neoadjuvant therapy (NAT) or upfront surgery (UPS). We used maximum selected rank statistics and a conditional inference tree approach to determine optimal LNY cutoffs for each subgroup. Kaplan-Meier curves and Cox proportional hazards models were employed to assess cancer-specific survival (CSS) and identify independent prognostic factors.Results: Distinct LNY thresholds were identified for N0 (>13) and N+ (>10) cohorts, with the highest cutoffs in N0-NAT subgroups (>27). Across all analyses, patients exceeding these LNY cutoffs demonstrated significantly prolonged CSS. The N0-NAT group with LNY >27 achieved the longest median survival (60 months), whereas N+ patients undergoing UPS with LNY ≤10 had the poorest outcomes (16 months). Multivariate Cox regressions consistently showed that higher LNY was an independent predictor of improved survival.Conclusions: Higher LNY thresholds than the current AJCC standard of 12 appear beneficial for more accurate staging and improved survival in resected PDAC. Tailoring LNY goals based on nodal status and treatment modality may further refine prognostic stratification and guide more effective therapeutic strategies.","PeriodicalId":19976,"journal":{"name":"Pancreatology","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144132793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Minimally invasive versus open distal pancreatectomy for pancreatic Tumors: An updated meta-analysis and meta-regression. 微创与开放式胰腺远端切除术治疗胰腺肿瘤：最新的荟萃分析和荟萃回归。

IF 2.8 2区医学

Pancreatology Pub Date : 2025-05-13 DOI: 10.1016/j.pan.2025.05.004

João Victor de Oliveira Ramos, João Vitor Andrade Fernandes, Carlos Henrique de Oliveira Ferreira, Gabrielle de Lacerda Dantas Henrique, Ramon Lacerda de Souza, Yan Gadelha de Abrantes Formiga, Fabyan Esberard de Lima Beltrão

{"title":"Minimally invasive versus open distal pancreatectomy for pancreatic Tumors: An updated meta-analysis and meta-regression.","authors":"João Victor de Oliveira Ramos, João Vitor Andrade Fernandes, Carlos Henrique de Oliveira Ferreira, Gabrielle de Lacerda Dantas Henrique, Ramon Lacerda de Souza, Yan Gadelha de Abrantes Formiga, Fabyan Esberard de Lima Beltrão","doi":"10.1016/j.pan.2025.05.004","DOIUrl":"https://doi.org/10.1016/j.pan.2025.05.004","url":null,"abstract":"This study aims to compare the efficacy and safety of minimally invasive distal pancreatectomy (MIDP) and open distal pancreatectomy (ODP) for pancreatic neoplasms. A meta-analysis following PRISMA guidelines, registered on PROSPERO, included randomized controlled trials (RCTs) and propensity-score matched studies. Data from Cochrane Central, PubMed, and Embase were analyzed, focusing on procedure efficacy (e.g., length of hospital stay and reoperations), oncologic outcomes (e.g., R0 resections), surgical outcomes (e.g., blood loss and operative time), and postoperative outcomes (e.g., 90-day mortality, severe complications, pancreatic fistula). Among 23 studies, MIDP showed significantly reduced 90-day mortality (OR: 0.57, p = 0.03), severe (CDC ≥ III) complications (OR: 0.81, p = 0.04), hospital stay (MD: 2.38 days, p < 0.01), reoperations (OR: 0.65, p < 0.01) and blood loss (MD: 137.66 mL, p < 0.01) compared to ODP. No significant differences were found in postoperative pancreatic fistula (OR: 1.06, p = 0.74) or operative time (MD: 1.95 min, p = 0.87). ODP showed a significantly lower incidence of R0 resections (OR: 1.57, p < 0.01). Subgroup analyses of RCTs favored MIDP for 90-day mortality, severe complications, and hospital stay, but found no differences in pancreatic fistula or operative time. Meta-regression identified age and tumor size as influential covariates. MIDP offers superior outcomes in procedure efficacy, surgical and postoperative outcomes compared to ODP. These findings highlight MIDP as a safe and effective alternative for pancreatic surgery, supported by robust subgroup and sensitivity analyses.","PeriodicalId":19976,"journal":{"name":"Pancreatology","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144094582","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Reply to the Letter to the Editor regarding "Early detection of pancreatic cancer: Study design and analytical considerations in biomarker discovery and early phase validation studies". 回复关于“胰腺癌早期检测：生物标志物发现和早期验证研究中的研究设计和分析考虑”的致编辑的信。

IF 2.8 2区医学

Pancreatology Pub Date : 2025-05-10 DOI: 10.1016/j.pan.2025.04.017

Douglas M Mahoney, Lynette M Smith, Qiao-Li Wang, Grant Izmirlian, Gregory A Coté, Michael G Goggins, Randall Brand, Ann L Oberg

引用次数: 0

Chronic pancreatitis and extra pancreatic cancers- A systematic review and meta analysis. 慢性胰腺炎和胰腺癌：系统回顾和meta分析。

IF 2.8 2区医学

Pancreatology Pub Date : 2025-05-10 DOI: 10.1016/j.pan.2025.05.003

Shauntelle Quammie, Colin John Crooks, Abdulsalam Aliyu, Guruprasad P Aithal, Aloysious D Aravinthan

{"title":"Chronic pancreatitis and extra pancreatic cancers- A systematic review and meta analysis.","authors":"Shauntelle Quammie, Colin John Crooks, Abdulsalam Aliyu, Guruprasad P Aithal, Aloysious D Aravinthan","doi":"10.1016/j.pan.2025.05.003","DOIUrl":"https://doi.org/10.1016/j.pan.2025.05.003","url":null,"abstract":"Introduction: Chronic pancreatitis (CP) is a known risk factor for pancreatic cancer; however its association to extra pancreatic (EP) cancers remains inadequately explored. The aim of this systematic review is to investigate the evidence for CP as a risk factor for developing EP cancers.Method: Electronic search was conducted on Ovid Medline, EMBASE and Scopus from inception to January 27, 2024 to identify patients with CP who developed EP cancers. Prevalence and incidence of each cancer were calculated where possible from the reported numbers. A random effects meta-analysis was used to pool prevalence, incidence and hazard ratios (HR) of each EP cancer. Heterogeneity was assessed using I2. PROSPERO registration: CRD42024543050.Results: Sixteen (16) studies consisting of 117,163 CP patients met the eligibility criteria. 4015 (3.4%) patients developed 4019 EP cancers. The overall annual prevalence and incidence of EP cancers were 7962 (95% CI 5044-10880) per 100,000 CP patients and 1039 (95% CI 649-1663) per 100,000 person years. Lung cancer had the highest annual prevalence - (1540 (95% CI 667-2413) per 100,000 CP patients) and incidence (260 (95% CI 120-390) per 100,000 person years). The pooled HR were 1.31 (95% CI 1.03-1.66) and 1.58 (95% CI 1.27-1.98) for adjusted lung cancer and crude liver cancer in patients with CP compared to patients without CP, respectively.Conclusion: Patients with CP have an increased risk of developing EP cancers compared to patients without CP, in particular lung and liver cancer which had the highest relative risk. Shared risk factor modifications, such as smoking cessation and alcohol reduction, could lower the risk of common EP cancers. Further, implementing non-invasive screening measures may aid in early diagnosis in this high-risk group.","PeriodicalId":19976,"journal":{"name":"Pancreatology","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-05-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144094579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Suboptimal adherence to surveillance in high-risk individuals for pancreatic cancer at a tertiary care academic center: Lessons from real-world surveillance patterns. 三级医疗学术中心胰腺癌高危人群监测的次优依从性：来自现实世界监测模式的经验教训

IF 2.8 2区医学

Pancreatology Pub Date : 2025-05-10 DOI: 10.1016/j.pan.2025.05.002

Alice A Lee, Abigail Twoy, Audrey Sutton, Naoko Fushimi, Walter G Park

{"title":"Suboptimal adherence to surveillance in high-risk individuals for pancreatic cancer at a tertiary care academic center: Lessons from real-world surveillance patterns.","authors":"Alice A Lee, Abigail Twoy, Audrey Sutton, Naoko Fushimi, Walter G Park","doi":"10.1016/j.pan.2025.05.002","DOIUrl":"https://doi.org/10.1016/j.pan.2025.05.002","url":null,"abstract":"Background/objectives: Screening for pancreatic ductal adenocarcinoma alters the course of disease among high-risk individuals (HRIs) and is recommended by multiple societies including the International Cancer of the Pancreas Screening Consortium, American Gastroenterological Association, and American Society of Gastrointestinal Endoscopy. However, there are limited analyses on the screening rates and barriers to adherence among HRIs. This study aims to describe real-world longitudinal screening adherence of a HRI surveillance cohort and identify potential barriers to adherence.Methods: Patients followed by Stanford's Benign Pancreas Clinic were identified as HRIs if they met screening criteria per the latest abovementioned screening guidelines, and were included in our study if they underwent at least 1 screening exam. Data on HRIs were obtained retrospectively from our hospital's electronic health record system. Patient and screening characteristics were analyzed by adherence rates.Results: 262 HRIs undergoing recommended screening were identified. The mean follow-up time per patient was 4.9 years and the mean successful annual screening rate within the entire cohort was 67%. HRIs in the lowest quartile of adherence were more likely to have more EUS rather than MRI surveillance exams compared to those who were completely adherent (p = 0.01). HRIs who were completely adherent were also an older cohort compared to those with non-complete adherence (p = 0.02) or in the lowest quartile of adherence (p = 0.01).Conclusions: It is difficult to achieve high adherence rates for annual pancreatic cancer screening of HRIs as recommended by the latest guidelines. Age and screening modality may be factors that contribute to adherence difficulty.","PeriodicalId":19976,"journal":{"name":"Pancreatology","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-05-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144094590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Performance of a novel three-prong asymmetric tip needle in EUS-guided tissue sampling of pancreatic solid Lesions: Implications for diagnosis and molecular profiling. 一种新型三尖不对称尖针在eus引导下胰腺实体病变组织采样中的表现：诊断和分子谱分析的意义。

IF 2.8 2区医学

Pancreatology Pub Date : 2025-05-09 DOI: 10.1016/j.pan.2025.04.015

Alberto Busatto, Livia Zornetta, Elisa Pinto, Vittorio Storer, Barbara Perini, Alessandro Borsato, Matteo Ghisa, Francesco Ferrara

引用次数: 0

Reply to the letter to editor regarding critical appraisal of the study on postoperative pancreatic enzyme replacement therapy after total pancreatectomy. 回复关于对全胰切除术后胰酶替代治疗研究的批评性评价的致编辑信。

IF 2.8 2区医学

Pancreatology Pub Date : 2025-05-02 DOI: 10.1016/j.pan.2025.05.001

Ryuta Shintakuya, Kenichiro Uemura, Tatsuaki Sumiyoshi, Kenjiro Okada, Kenta Baba, Takumi Harada, Yasutaka Ishii, Shiro Oka, Koji Arihiro, Yoshiaki Murakami, Shinya Takahashi

引用次数: 0