Pancreatology最新文献

{"title":"Patient experience with endoscopic ultrasound and magnetic resonance cholangiopancreatography for pancreatic cancer screening (The PATRIOT study)","authors":"Andy Silva-Santisteban Merino ,&nbsp;Kevin Enrique Ariza Manzano ,&nbsp;Sarah Ballou,&nbsp;Abraham Fourie Bezuidenhout,&nbsp;Katharine A. Germansky,&nbsp;Mandeep S. Sawhney","doi":"10.1016/j.pan.2025.12.024","DOIUrl":"10.1016/j.pan.2025.12.024","url":null,"abstract":"<div><h3>Background</h3><div>EUS and MRCP are considered equivalent for pancreatic cancer screening. ASGE guidelines suggest that the choice between these modalities should be based upon patient preferences, however, there is limited data to help guide clinicians.</div></div><div><h3>Methods</h3><div>All consecutive patients undergoing pancreatic cancer screening who had undergone both EUS and MRCP between 2021 and 2024 were identified. We also selected a comparison cohort of patients undergoing pancreatic cyst surveillance. A survey to elicit patient preferences and experience regarding physical discomfort, anxiety, dread, convenience, reassurance and cancer worry was administered to both groups.</div></div><div><h3>Results</h3><div>Of 150 pancreatic cancer screening patients approached, 74 % agreed to participate. We compared mean response scores between EUS and MRCP and found patients favored EUS: less claustrophobia(p = 0.001), less dread(p = 0.02), more reassurance(p = 0.01), and more likely to recommend to family(p = 0.059). While 41.4 % reported no overall preference, 33.3 % preferred EUS and 25.2 % MRCP. Of 70/150(47 %) pancreatic cyst surveillance patients who responded, no difference in anxiety, dread or reassurance was noted between EUS and MRCP, but patients reported more claustrophobia with MRCP(p = 0.001). However, patients were more likely to recommend MRCP to family(p = 0.055). While 36.8 % reported no overall preference, 44.1 % preferred MRCP and 19.1 % EUS. Higher levels of cancer worry were reported by screening than cyst surveillance patients, but both groups reported that this rarely interfered with daily activities.</div></div><div><h3>Conclusions</h3><div>Almost 60 % of patients prefer one screening modality over the other, with a trend towards screening patients favoring EUS and cyst surveillance patients MRCP. These findings support a patient-centered individualized approach to pancreatic cancer screening.</div></div>","PeriodicalId":19976,"journal":{"name":"Pancreatology","volume":"26 2","pages":"Pages 259-264"},"PeriodicalIF":2.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146030355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"High prevalence of anxiety and depression among patients with acute and chronic pancreatitis: A systematic review and meta-analysis","authors":"Tibor Dániel Fehér ,&nbsp;Mahmoud Obeidat ,&nbsp;Boglárka Lilla Szentes ,&nbsp;Renáta Papp ,&nbsp;Brigitta Teutsch ,&nbsp;Marie Anne Engh ,&nbsp;Szilárd Váncsa ,&nbsp;Réka Csaba ,&nbsp;Lilla Réthy ,&nbsp;Péter Hegyi ,&nbsp;Rita Nagy","doi":"10.1016/j.pan.2026.01.006","DOIUrl":"10.1016/j.pan.2026.01.006","url":null,"abstract":"<div><h3>Background</h3><div>Depression and anxiety are increasingly recognized as important comorbidities in gastrointestinal (GI) disorders, influencing disease burden and patient outcomes. However, their prevalence in pancreatitis, both in its acute (AP) and chronic (CP) forms, remains underexplored. This systematic review and meta-analysis aimed to quantify the burden of depressive and anxiety symptoms among patients with pancreatitis.</div></div><div><h3>Methods</h3><div>We conducted a systematic search (PROSPERO: CRD42023481739) across three databases: MEDLINE, Embase, and CENTRAL, to identify studies reporting on the prevalence of depression and anxiety symptoms in patients with AP or CP, as of November 10, 2023. The random-effects model was used to calculate the pooled proportion rate and pooled means of different anxiety/depression scores, along with 95 % confidence intervals (CI).</div></div><div><h3>Results</h3><div>In total, 44 studies were included. Anxiety was observed in 23 % (CI: 7 %–54 %) of the AP cases, and it was observed in 31 % (CI: 23 %–39 %) of the <u>CP</u> cases. Depressive symptoms were observed in 29 % (CI: 14 %–51 %) of the AP patients, while in CP cases, the prevalence was 39 % (CI: 30 %–48 %). The pooled single-mean analysis of psychological questionnaire data confirms clinically significant levels of both depressive and anxiety symptoms. Mean scores exceeded established cut-off points across all measures: CESD-10 (14.30 [CI: 6.69–21.92]), HADS-depression (8.23 [CI: 4.53–11.94]), SES (49.29 [CI: 44.01–54.57]), HADS-anxiety (8.67 [CI: 6.89–10.46]), and SAS (47.75 [CI: 35.05–60.45]). These findings indicate that many participants experienced symptom levels beyond the normative range. Overall, a low risk of bias was observed; however, several studies were identified as high risk due to reporting limitations.</div></div><div><h3>Conclusions</h3><div>Our findings reveal a notably high prevalence of depression and anxiety in pancreatitis, exceeding global averages and rates seen in other GI disorders. These findings warrant routine psychological screening, ongoing follow-up, and the integration of mental health professionals into multidisciplinary care teams are therefore warranted.</div></div>","PeriodicalId":19976,"journal":{"name":"Pancreatology","volume":"26 2","pages":"Pages 221-230"},"PeriodicalIF":2.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146137719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of failed ERCP on complications after EUS-guided choledochoduodenostomy with lumen-apposing metal stents in pancreatic cancer","authors":"A.M. Hernández Pérez,&nbsp;A. Sánchez Yagüe,&nbsp;R. Rivera Irigoin,&nbsp;J.K. Bisso Zein,&nbsp;C. Verdejo Gil,&nbsp;A. Pérez Aisa","doi":"10.1016/j.pan.2026.01.071","DOIUrl":"10.1016/j.pan.2026.01.071","url":null,"abstract":"","PeriodicalId":19976,"journal":{"name":"Pancreatology","volume":"26 2","pages":"Page 334"},"PeriodicalIF":2.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147412841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Validation and clinical usefulness of the patient-reported outcome measure PEI-Q for assessing symptoms and therapeutic response to pancreatic enzyme replacement therapy in pancreatic exocrine insufficiency of different etiologies: Results from a European registry","authors":"J.E. Domínguez Muñoz ,&nbsp;Y. Domínguez Novoa ,&nbsp;P. Hegyi ,&nbsp;G. Capurso ,&nbsp;X. Martínez-Seara ,&nbsp;O. Eperjesi ,&nbsp;G. Lauri ,&nbsp;J. Iglesias García","doi":"10.1016/j.pan.2026.01.058","DOIUrl":"10.1016/j.pan.2026.01.058","url":null,"abstract":"","PeriodicalId":19976,"journal":{"name":"Pancreatology","volume":"26 2","pages":"Page 329"},"PeriodicalIF":2.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147412943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nutritional evolution after pancreatoduodenectomy. Is there differences depending on the pancreatic anastomosis (Pancreatogastrostomy vs Pancreatoyeyunostomy)?","authors":"S. Mansilla Díaz,&nbsp;L.C. Hinojosa Arco,&nbsp;R. Gómez Pérez,&nbsp;A. de Laguno de Luna,&nbsp;J. Roldán de la Rua,&nbsp;J.M. García Almeida,&nbsp;R. de Luna Díaz,&nbsp;M.A. Suárez Muñoz","doi":"10.1016/j.pan.2026.01.035","DOIUrl":"10.1016/j.pan.2026.01.035","url":null,"abstract":"","PeriodicalId":19976,"journal":{"name":"Pancreatology","volume":"26 2","pages":"Page 319"},"PeriodicalIF":2.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147415174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"EUS-guided gastroenterostomy with lumen-apposing metal stents: comparison between fluoroscopic and non-fluoroscopic techniques in malignant duodenal obstruction","authors":"A.M. Hernández Pérez,&nbsp;A. Sánchez Yagüe,&nbsp;R. Rivera Irigoin,&nbsp;J.K. Bisso Zein,&nbsp;C. Verdejo Gil,&nbsp;A. Pérez Aisa","doi":"10.1016/j.pan.2026.01.047","DOIUrl":"10.1016/j.pan.2026.01.047","url":null,"abstract":"","PeriodicalId":19976,"journal":{"name":"Pancreatology","volume":"26 2","pages":"Pages 322-323"},"PeriodicalIF":2.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147415753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"In memoriam: Eugene P. DiMagno, MD 1937-2025","authors":"Peter Layer ,&nbsp;Gerald Holtmann ,&nbsp;Peter Malfertheiner ,&nbsp;Alberto Maringhini ,&nbsp;Massimo Raimondo ,&nbsp;Suresh T. Chari","doi":"10.1016/j.pan.2026.02.009","DOIUrl":"10.1016/j.pan.2026.02.009","url":null,"abstract":"","PeriodicalId":19976,"journal":{"name":"Pancreatology","volume":"26 2","pages":"Pages 201-202"},"PeriodicalIF":2.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147415756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical manifestations and response to treatment in patients with autoinmune pancreatitis type 1 related to IgG4: Experience in a tertiary care hospital","authors":"R.M. Vallejo Vigo,&nbsp;L. Álvarez Ortiz,&nbsp;E. Rubio Romero,&nbsp;G. Ontanilla Clavijo","doi":"10.1016/j.pan.2026.01.020","DOIUrl":"10.1016/j.pan.2026.01.020","url":null,"abstract":"","PeriodicalId":19976,"journal":{"name":"Pancreatology","volume":"26 2","pages":"Page 314"},"PeriodicalIF":2.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147416555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis of the effectiveness of therapeutic plasma exchange in the resolution of organ failure in hypertriglyceridemia-induced acute pancreatitis","authors":"S. Homdedeu,&nbsp;S. Salord,&nbsp;L. Secanella,&nbsp;N. Peláez,&nbsp;M. Sorribas,&nbsp;D. Ortiz,&nbsp;E. Santafosta,&nbsp;K. Auquilla,&nbsp;N. García,&nbsp;J. Busquets","doi":"10.1016/j.pan.2026.01.022","DOIUrl":"10.1016/j.pan.2026.01.022","url":null,"abstract":"","PeriodicalId":19976,"journal":{"name":"Pancreatology","volume":"26 2","pages":"Page 315"},"PeriodicalIF":2.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147416556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recurrent acute pancreatitis due to periampullary duodenal diverticula: A case of Lemmel’s syndrome requiring pancreaticoduodenectomy","authors":"A. Navarro Pueyo,&nbsp;G. Bernal Bandrés,&nbsp;M. Escuín Sanmartín,&nbsp;S. García Mateo,&nbsp;M. Galochino Ballano,&nbsp;M. Fernández Arquillué,&nbsp;M. Latre Santos,&nbsp;E. Ceamanos Ibarra,&nbsp;L. Andreu Navarro,&nbsp;L. Pérez Pradas,&nbsp;V. Pardo Valenzuela,&nbsp;J. Millastre Bocos","doi":"10.1016/j.pan.2026.01.038","DOIUrl":"10.1016/j.pan.2026.01.038","url":null,"abstract":"","PeriodicalId":19976,"journal":{"name":"Pancreatology","volume":"26 2","pages":"Page 320"},"PeriodicalIF":2.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147394350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}