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Can negative lymph node involvement and resection-free margins (ypT1–3N0R0) compete the disease-free survival benefit of a pathologic complete response (ypT0N0R0) in resected pancreatic cancer post neoadjuvant treatment? 淋巴结阴性受累和无切除边缘（ypT1-3N0R0）是否可以完成切除胰腺癌新辅助治疗后病理完全缓解（ypT0N0R0）的无病生存获益？
IF 2.7 2区 医学
Pancreatology Pub Date : 2026-03-01 Epub Date: 2025-12-01 DOI: 10.1016/j.pan.2025.11.020
Evangelia Florou , Yoh Zen , Parthi Srinivasan , Andreas Prachalias
{"title":"Can negative lymph node involvement and resection-free margins (ypT1–3N0R0) compete the disease-free survival benefit of a pathologic complete response (ypT0N0R0) in resected pancreatic cancer post neoadjuvant treatment?","authors":"Evangelia Florou , Yoh Zen , Parthi Srinivasan , Andreas Prachalias","doi":"10.1016/j.pan.2025.11.020","DOIUrl":"10.1016/j.pan.2025.11.020","url":null,"abstract":"","PeriodicalId":19976,"journal":{"name":"Pancreatology","volume":"26 2","pages":"Pages 287-289"},"PeriodicalIF":2.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145687716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Glucagon-like Peptide-1 receptor agonists rarely cause de novo acute pancreatitis but often result in serum lipase elevations of unclear clinical significance 胰高血糖素样肽-1受体激动剂很少引起新发急性胰腺炎，但经常导致血清脂肪酶升高，临床意义不明确。
IF 2.7 2区 医学
Pancreatology Pub Date : 2026-03-01 Epub Date: 2025-12-25 DOI: 10.1016/j.pan.2025.12.021
Jianing Li, Aditya Chandrashekar, Richu Ravikumar, Elham Afghani, Vikesh K. Singh, Venkata Akshintala
{"title":"Glucagon-like Peptide-1 receptor agonists rarely cause de novo acute pancreatitis but often result in serum lipase elevations of unclear clinical significance","authors":"Jianing Li, Aditya Chandrashekar, Richu Ravikumar, Elham Afghani, Vikesh K. Singh, Venkata Akshintala","doi":"10.1016/j.pan.2025.12.021","DOIUrl":"10.1016/j.pan.2025.12.021","url":null,"abstract":"","PeriodicalId":19976,"journal":{"name":"Pancreatology","volume":"26 2","pages":"Pages 299-301"},"PeriodicalIF":2.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145952653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Spontaneous cysto-biliary communication in walled-off necrosis of the pancreas 胰腺壁闭塞性坏死中自发的胆囊-胆道交通。
IF 2.7 2区 医学
Pancreatology Pub Date : 2026-03-01 Epub Date: 2026-01-26 DOI: 10.1016/j.pan.2026.01.075
Venkatesh Vaithiyam, Amit Bagrodia, Keval Vora, Nikhil Sirohi, Shrey Bhatt, Ujjwal Sonika, Ashok Dalal, Ajay Kumar, Siddharth Srivastava, Sanjeev Sachdeva
{"title":"Spontaneous cysto-biliary communication in walled-off necrosis of the pancreas","authors":"Venkatesh Vaithiyam, Amit Bagrodia, Keval Vora, Nikhil Sirohi, Shrey Bhatt, Ujjwal Sonika, Ashok Dalal, Ajay Kumar, Siddharth Srivastava, Sanjeev Sachdeva","doi":"10.1016/j.pan.2026.01.075","DOIUrl":"10.1016/j.pan.2026.01.075","url":null,"abstract":"","PeriodicalId":19976,"journal":{"name":"Pancreatology","volume":"26 2","pages":"Pages 310-311"},"PeriodicalIF":2.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146093688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Accelerated focused open necrosectomy-based step-cross versus conventional step-up approach in infected necrotizing pancreatitis 在感染性坏死性胰腺炎中，基于加速聚焦开放性坏死切除术的阶梯交叉与传统的阶梯交叉
IF 2.7 2区 医学
Pancreatology Pub Date : 2026-03-01 Epub Date: 2026-01-26 DOI: 10.1016/j.pan.2026.01.073
Shuai Li , Wutao Wang , Kaiming Li , Minchun Bu , Jing Zhou , Bo Ye , Lu Ke , Zhihui Tong , Weiqin Li , Gang Li
{"title":"Accelerated focused open necrosectomy-based step-cross versus conventional step-up approach in infected necrotizing pancreatitis","authors":"Shuai Li ,&nbsp;Wutao Wang ,&nbsp;Kaiming Li ,&nbsp;Minchun Bu ,&nbsp;Jing Zhou ,&nbsp;Bo Ye ,&nbsp;Lu Ke ,&nbsp;Zhihui Tong ,&nbsp;Weiqin Li ,&nbsp;Gang Li","doi":"10.1016/j.pan.2026.01.073","DOIUrl":"10.1016/j.pan.2026.01.073","url":null,"abstract":"<div><h3>Background</h3><div>Infected necrotizing pancreatitis (INP) patients requiring open necrosectomy (ON) as part of the step-up approach generally face high postoperative mortality. Our center proposed the step-cross approach as a supplement, but supporting evidence remains limited. This study aimed to compare clinical outcomes between the step-cross and step-up approaches in INP patients.</div></div><div><h3>Methods</h3><div>This retrospective cohort study included adult INP patients admitted to our center from 2017 to 2022. The step-cross approach consisted of percutaneous catheter drainage, followed by accelerated focused ON and personalized drainage or debridement as needed. Propensity score matching (PSM) was used to adjust for confounders.</div></div><div><h3>Results</h3><div>Of 509 included patients (median age 46 [34–55] years, 67.6 % male), 454 (89.2 %) and 55 (10.8 %) underwent the step-up and step-cross approach respectively. Overall, 180-day mortality was 20.2 % (103/509): 83 (18.3 %) in the step-up group and 20 (36.4 %) in step-cross group. After PSM (53 matched pairs), 180-day mortality did not differ significantly (35.9 %vs 49.1 %, relative risk [RR] and 95 % confidence interval [CI] with the step-cross approach = 0.73 [0.46–1.15], P = 0.169), but the step-cross group was associated with lower CRRT duration (2 [0, 16] vs 15 [3.5, 22] days, P = 0.005) and fewer minimally invasive necrosectomy procedures. Complications, hospital stays and costs were comparable between groups.</div></div><div><h3>Conclusions</h3><div>The step-cross approach is a safe complementary strategy to the step-up approach, demonstrating trends toward lower mortality and reduced organ support requirements in selected INP patients. Nevertheless, these findings require validation through large-scale prospective studies.</div></div>","PeriodicalId":19976,"journal":{"name":"Pancreatology","volume":"26 2","pages":"Pages 231-237"},"PeriodicalIF":2.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146097373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reply to the Letter to Editor regarding the role of circular RNA circ0001415 in acute pancreatitis 回复关于环状RNA circ0001415在急性胰腺炎中的作用的致编辑信。
IF 2.7 2区 医学
Pancreatology Pub Date : 2026-03-01 Epub Date: 2026-01-24 DOI: 10.1016/j.pan.2026.01.003
Yan Zhang , Shaolong Hao , Fang Nie , Hao Sun , Wenxiu Zhang , Lang Ji , Jiahui Qi , Ziyu Zhang , Wei Han
{"title":"Reply to the Letter to Editor regarding the role of circular RNA circ0001415 in acute pancreatitis","authors":"Yan Zhang ,&nbsp;Shaolong Hao ,&nbsp;Fang Nie ,&nbsp;Hao Sun ,&nbsp;Wenxiu Zhang ,&nbsp;Lang Ji ,&nbsp;Jiahui Qi ,&nbsp;Ziyu Zhang ,&nbsp;Wei Han","doi":"10.1016/j.pan.2026.01.003","DOIUrl":"10.1016/j.pan.2026.01.003","url":null,"abstract":"","PeriodicalId":19976,"journal":{"name":"Pancreatology","volume":"26 2","pages":"Pages 308-309"},"PeriodicalIF":2.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146166237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Chronological vs Physiological age: Surgical outcomes in elderly PDAC 年龄与生理年龄：老年PDAC的手术结果
IF 2.7 2区 医学
Pancreatology Pub Date : 2026-03-01 Epub Date: 2026-03-02 DOI: 10.1016/j.pan.2026.01.043
D. de la Iglesia, B. Agudo Castillo, A. Ruiz Casado
{"title":"Chronological vs Physiological age: Surgical outcomes in elderly PDAC","authors":"D. de la Iglesia,&nbsp;B. Agudo Castillo,&nbsp;A. Ruiz Casado","doi":"10.1016/j.pan.2026.01.043","DOIUrl":"10.1016/j.pan.2026.01.043","url":null,"abstract":"","PeriodicalId":19976,"journal":{"name":"Pancreatology","volume":"26 2","pages":"Page 321"},"PeriodicalIF":2.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147412614","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Improving ongoing care for patients with biliopancreatic diseases: Do we know how our hospital monographic medical consultations work? 改善对胆道胰腺疾病患者的持续护理：我们知道我们医院的专题医学咨询是如何工作的吗？
IF 2.7 2区 医学
Pancreatology Pub Date : 2026-03-01 Epub Date: 2026-03-02 DOI: 10.1016/j.pan.2026.01.021
R. Cuevas Algaba , J.X. Wu Wu , L. Ballesteros de Diego , P. Hernán Ocaña , T. Álvarez-Nava Torrego , S. Sáenz-López Pérez , R. Narro Bravo , M. Pérez-Carreras
{"title":"Improving ongoing care for patients with biliopancreatic diseases: Do we know how our hospital monographic medical consultations work?","authors":"R. Cuevas Algaba ,&nbsp;J.X. Wu Wu ,&nbsp;L. Ballesteros de Diego ,&nbsp;P. Hernán Ocaña ,&nbsp;T. Álvarez-Nava Torrego ,&nbsp;S. Sáenz-López Pérez ,&nbsp;R. Narro Bravo ,&nbsp;M. Pérez-Carreras","doi":"10.1016/j.pan.2026.01.021","DOIUrl":"10.1016/j.pan.2026.01.021","url":null,"abstract":"","PeriodicalId":19976,"journal":{"name":"Pancreatology","volume":"26 2","pages":"Page 315"},"PeriodicalIF":2.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147416554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of age and etiology on complications of acute pancreatitis: A real-world cohort study 年龄和病因对急性胰腺炎并发症的影响：一项真实世界队列研究
IF 2.7 2区 医学
Pancreatology Pub Date : 2026-03-01 Epub Date: 2026-03-02 DOI: 10.1016/j.pan.2026.01.028
I. Santamaría Vicario, M. Durá Gil, A. de la Fuente Gaztañaga, E. Martínez Moneo, A. Bausela Sainz, R. Fernández Bezanilla, C. Ibarra Ponce de León, N. Gendive Martín, C. Gil García Ollauri, I. Casado Morentin
{"title":"Impact of age and etiology on complications of acute pancreatitis: A real-world cohort study","authors":"I. Santamaría Vicario,&nbsp;M. Durá Gil,&nbsp;A. de la Fuente Gaztañaga,&nbsp;E. Martínez Moneo,&nbsp;A. Bausela Sainz,&nbsp;R. Fernández Bezanilla,&nbsp;C. Ibarra Ponce de León,&nbsp;N. Gendive Martín,&nbsp;C. Gil García Ollauri,&nbsp;I. Casado Morentin","doi":"10.1016/j.pan.2026.01.028","DOIUrl":"10.1016/j.pan.2026.01.028","url":null,"abstract":"","PeriodicalId":19976,"journal":{"name":"Pancreatology","volume":"26 2","pages":"Page 317"},"PeriodicalIF":2.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147416560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Thermal liquid biopsy (TLB): A promising diagnostic and screening tool for pancreatic ductal adenocarcinoma (PDAC) 热液活检（TLB）：一种有前途的胰腺导管腺癌（PDAC）诊断和筛查工具
IF 2.7 2区 医学
Pancreatology Pub Date : 2026-03-01 Epub Date: 2026-03-02 DOI: 10.1016/j.pan.2026.01.029
J. Millastre Bocos , S. Hermoso Durán , F.J. Falcó Martí , M. Ortiz de Solórzano , E. Ceamanos Ibarra , G. García Rayado , R. Velamazán Sandalinas , M. Galochino Ballano , P.F. Garrido , O. Abián Franco
{"title":"Thermal liquid biopsy (TLB): A promising diagnostic and screening tool for pancreatic ductal adenocarcinoma (PDAC)","authors":"J. Millastre Bocos ,&nbsp;S. Hermoso Durán ,&nbsp;F.J. Falcó Martí ,&nbsp;M. Ortiz de Solórzano ,&nbsp;E. Ceamanos Ibarra ,&nbsp;G. García Rayado ,&nbsp;R. Velamazán Sandalinas ,&nbsp;M. Galochino Ballano ,&nbsp;P.F. Garrido ,&nbsp;O. Abián Franco","doi":"10.1016/j.pan.2026.01.029","DOIUrl":"10.1016/j.pan.2026.01.029","url":null,"abstract":"","PeriodicalId":19976,"journal":{"name":"Pancreatology","volume":"26 2","pages":"Page 317"},"PeriodicalIF":2.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147414737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
New advanced imaging techniques associated with endoscopic ultrasound (EUS) in the differential diagnosis of solid pancreatic tumors 新的先进成像技术与内镜超声（EUS）在胰腺实体瘤鉴别诊断中的应用
IF 2.7 2区 医学
Pancreatology Pub Date : 2026-03-01 Epub Date: 2026-03-02 DOI: 10.1016/j.pan.2026.01.068
Y. Domínguez Novoa , J. Iglesias García , J. Lariño Noia , H. Lazare Iglesias , I. Abdulkader Nallib , J.E. Domínguez Muñoz
{"title":"New advanced imaging techniques associated with endoscopic ultrasound (EUS) in the differential diagnosis of solid pancreatic tumors","authors":"Y. Domínguez Novoa ,&nbsp;J. Iglesias García ,&nbsp;J. Lariño Noia ,&nbsp;H. Lazare Iglesias ,&nbsp;I. Abdulkader Nallib ,&nbsp;J.E. Domínguez Muñoz","doi":"10.1016/j.pan.2026.01.068","DOIUrl":"10.1016/j.pan.2026.01.068","url":null,"abstract":"","PeriodicalId":19976,"journal":{"name":"Pancreatology","volume":"26 2","pages":"Page 331"},"PeriodicalIF":2.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147412842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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