Peritoneal Dialysis International最新文献

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Ultrasound-guided Veress needle puncture for percutaneous peritoneal dialysis catheter placement. 超声引导下Veress针穿刺经皮腹膜透析置管。
IF 3.7 3区 医学
Peritoneal Dialysis International Pub Date : 2026-06-04 DOI: 10.1177/08968608261458975
Fumiaki Nogaki, Shintaro Kubo, Ryo Hatano, Masato Kamiya, Daiki Masuda, Taro Hirai, Noriyuki Suzuki
{"title":"Ultrasound-guided Veress needle puncture for percutaneous peritoneal dialysis catheter placement.","authors":"Fumiaki Nogaki, Shintaro Kubo, Ryo Hatano, Masato Kamiya, Daiki Masuda, Taro Hirai, Noriyuki Suzuki","doi":"10.1177/08968608261458975","DOIUrl":"https://doi.org/10.1177/08968608261458975","url":null,"abstract":"<p><p>Percutaneous peritoneal dialysis catheter placement using the Veress needle is considered safe; however, because the needle is usually inserted blindly, there is a risk of visceral or vascular injury. Although ultrasound guidance can reduce this risk, the puncture process has not been described in detail. We therefore illustrate the procedure using ultrasound images and schematic drawings.</p>","PeriodicalId":19969,"journal":{"name":"Peritoneal Dialysis International","volume":" ","pages":"8968608261458975"},"PeriodicalIF":3.7,"publicationDate":"2026-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148163796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Socioeconomic deprivation and clinical outcomes in patients receiving peritoneal dialysis: A 10-year propensity score matched cohort study from the United Kingdom. 接受腹膜透析患者的社会经济剥夺和临床结果:一项来自英国的10年倾向评分匹配队列研究。
IF 3.7 3区 医学
Peritoneal Dialysis International Pub Date : 2026-06-03 DOI: 10.1177/08968608261456392
Varun Mamidi, Ola Suliman, Henry Hl Wu, Joanne Collier, Joanne Martin, Helen Hurst, Dimitrios Poulikakos, David Lewis, Rajkumar Chinnadurai
{"title":"Socioeconomic deprivation and clinical outcomes in patients receiving peritoneal dialysis: A 10-year propensity score matched cohort study from the United Kingdom.","authors":"Varun Mamidi, Ola Suliman, Henry Hl Wu, Joanne Collier, Joanne Martin, Helen Hurst, Dimitrios Poulikakos, David Lewis, Rajkumar Chinnadurai","doi":"10.1177/08968608261456392","DOIUrl":"https://doi.org/10.1177/08968608261456392","url":null,"abstract":"<p><p>BackgroundSocioeconomic deprivation is an established determinant of adverse health outcomes. However, UK-specific data examining its impact on peritoneal dialysis (PD) outcomes remains generally unknown. This study evaluated associations between socioeconomic deprivation and clinical outcomes among patients receiving PD at a single UK center over a 10-year period.MethodsThis retrospective observational study included 648 adult patients who underwent PD catheter insertion between January 2015 and December 2024. Socioeconomic deprivation was assessed using the Index of Multiple Deprivation (IMD), with study cohorts categorized into quintiles from the least to the most deprived. Primary outcomes included all-cause mortality, transfer to hemodialysis (HD), and kidney transplantation. Secondary outcomes included cardiovascular events and PD-related infections, that is, peritonitis and exit-site infections. A 1:1 propensity score matching was performed to match for age, ethnicity, and smoking history to compare between the most deprived quintiles (MDQ) (i.e., quintiles 1 and 2) and the least deprived quintiles (LDQ) (i.e., quintiles 4 and 5). Cox proportional hazards models were used to evaluate associations between socioeconomic deprivation and outcomes.ResultsOf the 648 patients included, 41.7% resided in quintile 1. Patients in LDQ were significantly younger (median = 54 [IQR 42-67] vs. 64 [51-74] years, <i>p</i> < 0.001) and more likely to belong to ethnic minority backgrounds (24% vs. 7.7%, <i>p</i> < 0.001) compared to those in MDQ. Across all quintiles, no significant associations were observed between deprivation and all-cause mortality, transfer to HD, or kidney transplantation. In the propensity-matched cohort (n = 298), all-cause mortality was significantly higher among patients from MDQ compared to the LDQ (39.6% vs. 24.8%, <i>p</i> = 0.006). Social deprivation was noted to be an independent risk factor associated with all-cause mortality in the matched cohort (adjusted HR 2.08, 95% CI 1.37-3.10, <i>p</i> = 0.001). No significant associations were identified in relation to cardiovascular events, transfer to HD, kidney transplantation, or PD-related infections.ConclusionIn a propensity score-matched cohort from this single-center study, socioeconomic deprivation was independently associated with increased mortality among patients receiving PD. No significant associations were observed between socioeconomic deprivation with transfer to HD or kidney transplantation and PD-related infection complications.</p>","PeriodicalId":19969,"journal":{"name":"Peritoneal Dialysis International","volume":" ","pages":"8968608261456392"},"PeriodicalIF":3.7,"publicationDate":"2026-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148150796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ultrafiltration and free water transport during the peritoneal equilibration test: Clinical relevance of the association with intraperitoneal pressure. 腹膜平衡试验期间的超滤和自由水运输:与腹膜内压力相关的临床相关性
IF 3.7 3区 医学
Peritoneal Dialysis International Pub Date : 2026-06-03 DOI: 10.1177/08968608261456107
Alicia Sobrino-Pérez, Alfonso Pérez-Escudero, Luisa Sánchez-García, Sandra Sanz-Ballesteros, Carmen Felipe-Fernández, Esther Hernández-García, Victoria Oviedo-Gómez, Raquel de Toro-Casado, Astrid Rodríguez-Gómez, María José Fernández-Reyes, Vicente Pérez-Díaz
{"title":"Ultrafiltration and free water transport during the peritoneal equilibration test: Clinical relevance of the association with intraperitoneal pressure.","authors":"Alicia Sobrino-Pérez, Alfonso Pérez-Escudero, Luisa Sánchez-García, Sandra Sanz-Ballesteros, Carmen Felipe-Fernández, Esther Hernández-García, Victoria Oviedo-Gómez, Raquel de Toro-Casado, Astrid Rodríguez-Gómez, María José Fernández-Reyes, Vicente Pérez-Díaz","doi":"10.1177/08968608261456107","DOIUrl":"https://doi.org/10.1177/08968608261456107","url":null,"abstract":"<p><p>BackgroundIntraperitoneal pressure (IPP) may influence ultrafiltration (UF) in peritoneal dialysis (PD), but its clinical relevance under standard peritoneal equilibration test (PET) with 4.25%/3.86% dextrose remains uncertain.MethodsIn 96 unselected PD patients, we performed two 4.25%/3.86% PETs using 1L and 2L fill volumes. IPP, UF, glucose UF efficiency, sodium dip (Na-Dip) as a marker of free water transport (FWT), osmotic conductance to glucose (OCG), and solute transport parameters (D/P<sub>Creatinine</sub> and diffusion capacities (PS)) were assessed. Associations between IPP, UF parameters, and UF-related abnormalities were analyzed.ResultsThe 2L PET showed higher IPP, dialysate glucose concentration, and PS, and lower D/P<sub>Creatinine</sub>, as expected. However, an increase in water transport was not consistent: 21%, 66%, 29%, and 40% of patients showed in the 1L PET, respectively, higher UF, glucose UF efficiency, OCG, and Na-Dip. In 2L PET IPP was negatively correlated with UF (<i>r</i> = -0.221; <i>p</i> = 0.03) and Na-Dip (<i>r</i> = -0.210, <i>p</i> = 0.041). About 56% of patients presented at least one of the UF-related abnormalities identified (paradoxically higher UF with 1L, UF insufficiency (UF < 400 mL in 2L PET), and impaired FWT (Na-Dip≤5 mmol/L in 2L PET)). These patients had significantly higher IPP and reduced abdominal distensibility.ConclusionsThis study shows an association between IPP and UF in 4.25%/3.86% dextrose PET that appears clinically relevant. It also raises the hypothesis that IPP may be related to FWT in PD. These findings highlight the importance of IPP monitoring in PD and the need for further studies to characterize changes in FWT across variations in volume and intraperitoneal pressure.</p>","PeriodicalId":19969,"journal":{"name":"Peritoneal Dialysis International","volume":" ","pages":"8968608261456107"},"PeriodicalIF":3.7,"publicationDate":"2026-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148150854","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ten-year implementation of a National Peritoneal Dialysis Program in the Dominican Republic: A retrospective study. 多米尼加共和国国家腹膜透析计划的十年实施:一项回顾性研究。
IF 3.7 3区 医学
Peritoneal Dialysis International Pub Date : 2026-06-02 DOI: 10.1177/08968608261452388
Sergio Óscar Hernández Ordóñez, Erwin Iván Campos Echavarría, Elianny Sarina Polanco Brazoban, Zulma Bolena Lara Mayorga, Miguel Ángel Cuevas Budhart, José Carolino Divino-Filho, Janny Katherine, Alexandra Encarnación Ogando, Yocasta Lara Hernández, Alfonso Ramos-Sánchez
{"title":"Ten-year implementation of a National Peritoneal Dialysis Program in the Dominican Republic: A retrospective study.","authors":"Sergio Óscar Hernández Ordóñez, Erwin Iván Campos Echavarría, Elianny Sarina Polanco Brazoban, Zulma Bolena Lara Mayorga, Miguel Ángel Cuevas Budhart, José Carolino Divino-Filho, Janny Katherine, Alexandra Encarnación Ogando, Yocasta Lara Hernández, Alfonso Ramos-Sánchez","doi":"10.1177/08968608261452388","DOIUrl":"https://doi.org/10.1177/08968608261452388","url":null,"abstract":"<p><p>BackgroundChronic kidney disease (CKD) represents a growing public health challenge worldwide, particularly in countries with a medium sociodemographic index such as the Dominican Republic (DR), where both the incidence and prevalence of CKD have shown a sustained increase. In response, the DR government launched a national peritoneal dialysis (PD) program in 2013 to expand access to kidney replacement therapy (KRT).MethodsA retrospective analysis was conducted on the development and implementation of the national continuous ambulatory peritoneal dialysis (CAPD) program over ten years. The model was structured around three pillars: (1) a multidisciplinary team comprising nephrology, nursing, nutrition, psychology, and social work; (2) dedicated infrastructure for PD delivery; and (3) a management system driven by standardized processes and protocols, aligned with ISO certification standards. Patient care involved comprehensive baseline assessments, structured training, monthly follow-up, routine retraining, and home evaluations. Program performance was monitored through predefined clinical indicators.ResultsSince the implementation of the program, the PD penetration in DR increased from 2.7% to 22.4%, reaching 1118 patients by the end of 2024. This growth reflects the program's ability to improve access to KRT through a centralized and standardized care model. This model not only facilitated consistency in care delivery across participating centers but also enhanced the growth of PD.ConclusionsThe 10-year experience of the national PD program in the DR provides evidence for the feasibility and effectiveness of a standardized, patient-centered, and multidisciplinary PD program. The implementation of this program has significantly increased access to kidney replacement therapies and driven the sustained growth of KRT in the DR and provides a scalable model for the implementation of national PD initiatives in similar contexts.</p>","PeriodicalId":19969,"journal":{"name":"Peritoneal Dialysis International","volume":" ","pages":"8968608261452388"},"PeriodicalIF":3.7,"publicationDate":"2026-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148144261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association between specialist distribution and peritoneal dialysis use in Japan: An ecological study. 专家分布与日本腹膜透析使用之间的关系:一项生态学研究。
IF 3.7 3区 医学
Peritoneal Dialysis International Pub Date : 2026-06-02 DOI: 10.1177/08968608261456374
Ryuichi Yoshimura, Kosuke Matsui, Masahiro Egawa, Yasuko Ito, Kaori Yoshikane, Takafumi Ito
{"title":"Association between specialist distribution and peritoneal dialysis use in Japan: An ecological study.","authors":"Ryuichi Yoshimura, Kosuke Matsui, Masahiro Egawa, Yasuko Ito, Kaori Yoshikane, Takafumi Ito","doi":"10.1177/08968608261456374","DOIUrl":"https://doi.org/10.1177/08968608261456374","url":null,"abstract":"<p><p>BackgroundPeritoneal dialysis (PD) is a cost-effective, patient-centered kidney replacement therapy. However, its use in Japan remains limited. This study assessed regional variations in PD use and its association with involved specialists.MethodsThis cross-sectional study was conducted using data from the National Database Open Data Japan for the fiscal year 2022. PD use was evaluated using standardized claim ratios (SCRs), calculated from insurance claims for home PD management fee and PD catheter insertion. PD use was assessed among three types of specialists: Board Certified Nephrologists of the Japanese Society of Nephrology (JSN nephrologists), Fellows of the Japanese Society for Dialysis Therapy (JSDT fellows), and Certified Physicians of the Japanese Society for Peritoneal Dialysis (JSPD physicians). Associations between the number of specialists and SCRs for PD use were assessed using multivariable-adjusted negative binomial regression models.ResultsPD use varied across regions. SCRs ranged from 34.0 to 264.6 for home PD management fee and from 35.1 to 239.7 for PD catheter insertion. Each additional JSDT fellow per 100,000 population was associated with a 1.11-fold increase in SCR for home PD management fee (ß = 0.10; 95% CI: 0.02 to 0.19; <i>p</i> = 0.02) and a 1.13-fold increase in SCR for PD catheter insertion (ß = 0.12; 95% CI: 0.02 to 0.21; <i>p</i> = 0.02). Similar associations were observed for JSPD physicians, but not for JSN nephrologists.ConclusionRegional disparities in PD use exist in Japan. A higher number of specialists in PD care was associated with greater PD use.</p>","PeriodicalId":19969,"journal":{"name":"Peritoneal Dialysis International","volume":" ","pages":"8968608261456374"},"PeriodicalIF":3.7,"publicationDate":"2026-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148144273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Gastroscopy-associated peritonitis in PD: Toward targeted rather than universal prophylaxis. PD患者胃镜相关腹膜炎:定向预防而非普遍预防。
IF 3.7 3区 医学
Peritoneal Dialysis International Pub Date : 2026-05-28 DOI: 10.1177/08968608261456370
Dongjie Yan, Hongyu Chen
{"title":"Gastroscopy-associated peritonitis in PD: Toward targeted rather than universal prophylaxis.","authors":"Dongjie Yan, Hongyu Chen","doi":"10.1177/08968608261456370","DOIUrl":"https://doi.org/10.1177/08968608261456370","url":null,"abstract":"","PeriodicalId":19969,"journal":{"name":"Peritoneal Dialysis International","volume":" ","pages":"8968608261456370"},"PeriodicalIF":3.7,"publicationDate":"2026-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148043243","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Peritoneal dialysis therapy is a viable dialysis option for anuric patients: A retrospective cohort study. 腹膜透析治疗是无尿患者可行的透析选择:一项回顾性队列研究。
IF 3.7 3区 医学
Peritoneal Dialysis International Pub Date : 2026-05-23 DOI: 10.1177/08968608261450708
Yangyang Xin, Jing Guo, Shiyan Tu, Xilong Mo, Haishan Wu, Chunyan Yi, Joanne M Bargman, Xiao Yang
{"title":"Peritoneal dialysis therapy is a viable dialysis option for anuric patients: A retrospective cohort study.","authors":"Yangyang Xin, Jing Guo, Shiyan Tu, Xilong Mo, Haishan Wu, Chunyan Yi, Joanne M Bargman, Xiao Yang","doi":"10.1177/08968608261450708","DOIUrl":"https://doi.org/10.1177/08968608261450708","url":null,"abstract":"<p><p>IntroductionCompared to conventional, maintenance hemodialysis, peritoneal dialysis (PD) better preserves residual kidney function (RKF) in patients with kidney failure. However, few studies have investigated long-term prognosis of PD patients with anuria. This study aimed to investigate the long-term outcomes of anuric PD patients.MethodsIn this retrospective single-center cohort study, we included patients who received continuous ambulatory peritoneal dialysis (CAPD) and developed anuria between 2006 to 2020. The primary outcome was all-cause mortality. Secondary outcomes included technique survival and cardiovascular (CV) mortality. Cox proportional hazards regression, competing risk analysis, and subgroup analyses were performed to identify prognostic factors.ResultsA total of 615 anuric CAPD patients were included in the study, with a mean age of 47.8 ± 14.8 years at the onset of anuria. Prior to anuria onset, patients had received PD for a mean of 30.5 ± 23.0 months; following anuria onset, the median follow-up time was 40.3 months (interquartile range, 23.8-68.3). The 5- and 10-year patient survival rates following anuria onset were 68.2% and 37.1%, respectively, with corresponding technique survival rates of 75.4% and 50.6%. Cox regression analysis identified older age (cause-specific hazard ratio (cHR) 1.05; 95% confidence interval (CI) 1.04-1.06), lower serum albumin (cHR 0.97; 95% CI 0.94-1.00), diabetes (cHR 1.74; 95% CI 1.27-2.39), and cardiovascular disease (cHR 1.64; 95% CI 1.15-2.34) as independent predictors of all-cause mortality. Competing risk analysis revealed that higher glucose exposure (per 30 g/day increase) (subdistribution HR (sHR) 1.24; 95% CI 1.06-1.46) and peritonitis episodes (sHR 1.82; 95% CI 1.31-2.55) were independently associated with technique survival. Subgroup analyses revealed that the adverse prognostic effect of diabetes on all-cause mortality was more pronounced in patients aged <65 years than in those aged ≥65 years (<i>P</i> for interaction = 0.019).ConclusionsThis study demonstrates that PD patients who developed anuria can still achieve favorable long-term clinical outcomes, with a 5-year patient survival exceeding 68% and technique survival rates above 75%. These findings support the continued use of PD as a viable dialysis modality even after complete loss of RKF.</p>","PeriodicalId":19969,"journal":{"name":"Peritoneal Dialysis International","volume":" ","pages":"8968608261450708"},"PeriodicalIF":3.7,"publicationDate":"2026-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148006257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Opportunities and challenges in expanding access to peritoneal dialysis: A qualitative study in Latin America. 扩大获得腹膜透析的机会和挑战:拉丁美洲的一项定性研究。
IF 3.7 3区 医学
Peritoneal Dialysis International Pub Date : 2026-05-11 DOI: 10.1177/08968608261437688
Carolyn F Bernemann, Madeline Koul, Brett Cullis, William E Smoyer, Guillermo Hidalgo, Melvin Bonilla Felix, Mignon McCulloch, Grace Burleson, Natasha C Wright
{"title":"Opportunities and challenges in expanding access to peritoneal dialysis: A qualitative study in Latin America.","authors":"Carolyn F Bernemann, Madeline Koul, Brett Cullis, William E Smoyer, Guillermo Hidalgo, Melvin Bonilla Felix, Mignon McCulloch, Grace Burleson, Natasha C Wright","doi":"10.1177/08968608261437688","DOIUrl":"10.1177/08968608261437688","url":null,"abstract":"<p><p>IntroductionAcross Latin America (LA), accessibility and affordability of kidney replacement therapy varies, but the prevalence of treated kidney failure generally lags behind higher income regions. Hemodialysis (HD) is more common than peritoneal dialysis (PD) in most LA countries. Expanding PD may help increase dialysis access in acute and chronic kidney disease. This study explored trends in existing kidney replacement therapy programs in LA and the opportunities and challenges for improving PD services from the perspective of physicians.MethodsQualitative data were collected using open-ended, semistructured interviews. Physician participants were recruited from trainees attending a Saving Young Lives workshop on acute kidney injury and acute PD. Thematic analysis was used to identify emergent themes.ResultsThere were 15 study participants. We identified and explored two main themes: (1) Physicians face many barriers to adequately caring for all dialysis patients, including high costs, geography, equipment and supply limitations, and lack of specialists; and (2) Increasing dialysis access through PD presents opportunities and challenges.ConclusionsWhile there are some dialysis programs in LA in which all patients have access to adequate care and dialysis is fully funded, there are many programs with inadequate capacity and funding. PD presents an opportunity to improve dialysis access in LA, particularly for currently underserved patient populations, but challenges related to staff training, supply access, and patient factors must be addressed for PD programs to be sustainable.</p>","PeriodicalId":19969,"journal":{"name":"Peritoneal Dialysis International","volume":" ","pages":"8968608261437688"},"PeriodicalIF":3.7,"publicationDate":"2026-05-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147869331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Peritoneal dialysis results in similar outcomes to extracorporeal dialysis in acute kidney injury: A systematic review and meta-analysis. 腹膜透析与体外透析治疗急性肾损伤的结果相似:一项系统回顾和荟萃分析。
IF 3.7 3区 医学
Peritoneal Dialysis International Pub Date : 2026-05-08 DOI: 10.1177/08968608261448781
Rajiv Hans Menghrajani, Mirtha C Almanzar, Maria Angela Matabang, Saifudheen Faroog, Siena Placino, Anika Sinha, John Paul Aparece, Ankur D Shah
{"title":"Peritoneal dialysis results in similar outcomes to extracorporeal dialysis in acute kidney injury: A systematic review and meta-analysis.","authors":"Rajiv Hans Menghrajani, Mirtha C Almanzar, Maria Angela Matabang, Saifudheen Faroog, Siena Placino, Anika Sinha, John Paul Aparece, Ankur D Shah","doi":"10.1177/08968608261448781","DOIUrl":"https://doi.org/10.1177/08968608261448781","url":null,"abstract":"<p><p>BackgroundThe choice of kidney replacement therapy (KRT) modality for treatment of dialysis requiring acute kidney injury (AKI-D) is underappreciated as a modifiable factor that can impact outcomes. Peritoneal dialysis (PD) and extracorporeal dialysis are both established modalities for treatment of kidney failure; their comparative effectiveness in AKI remains controversial. We conducted a systematic review and meta-analysis to compare clinical outcomes between PD and extracorporeal dialysis in patients with AKI.MethodsWe systematically searched Medline, Embase, and Cochrane Central Register of Controlled Trials from inception through November 2024 for randomized controlled trials comparing PD with extracorporeal dialysis in adult patients with AKI requiring KRT. The primary outcome was mortality. Secondary outcomes included kidney function recovery, time to kidney function recovery, and infectious complications. We conducted meta-analyses using random-effects models and assessed risk of bias using the Cochrane Risk of Bias tool 2.0.ResultsAbout 358 records were identified, of which 7 were included in quantitative meta-analysis. We found no significant difference in mortality between PD and extracorporeal dialysis (odds ratio [OR] 1.05; 95% confidence interval [CI], 0.62-1.76; <i>p</i> = 0.87). Event rates were similar between groups (PD: 56.1%, extracorporeal: 56.5%). Kidney function recovery rates were comparable (OR 1.26; 95% CI, 0.81-1.95; <i>p</i> = 0.30), though time to kidney function recovery was significantly shorter with PD (mean difference -3.34 days, 95% CI -3.95 to -2.73, <i>p</i> < 0.00001). Infection rates were similar between modalities (OR 1.02, 95% CI 0.47-2.22, <i>p</i> = 0.96).ConclusionThis meta-analysis demonstrates comparable clinical outcomes between PD and extracorporeal dialysis for AKI management across key metrics including mortality, kidney function recovery, and infectious complications. PD was associated with faster time to kidney function recovery. These findings support the use of PD as an equally effective treatment for AKI-D. Further research is needed to evaluate patient-reported outcomes and patient modality preference.</p>","PeriodicalId":19969,"journal":{"name":"Peritoneal Dialysis International","volume":" ","pages":"8968608261448781"},"PeriodicalIF":3.7,"publicationDate":"2026-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147841513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hypertension management in pediatric peritoneal dialysis: A scoping review. 儿童腹膜透析中的高血压管理:一项范围综述。
IF 3.7 3区 医学
Peritoneal Dialysis International Pub Date : 2026-05-06 DOI: 10.1177/08968608261447433
Sameer Parashar, Kyle Backston, Adam Grden, Nafees Sathik, Yap Hui Kim, Mignon McCulloch, Rupesh Raina
{"title":"Hypertension management in pediatric peritoneal dialysis: A scoping review.","authors":"Sameer Parashar, Kyle Backston, Adam Grden, Nafees Sathik, Yap Hui Kim, Mignon McCulloch, Rupesh Raina","doi":"10.1177/08968608261447433","DOIUrl":"https://doi.org/10.1177/08968608261447433","url":null,"abstract":"<p><p>BackgroundPeritoneal dialysis (PD) is a prominent treatment option for children with kidney failure. However, cardiovascular disease remains the leading cause of both morbidity and early mortality in this pediatric population, with 50-70% of patients experiencing hypertension. This scoping review aims to assess pediatric hypertension management among those receiving PD, along with exploring new potential techniques to optimize care.MethodsPubMed and Web of Science were used to conduct a literature search using PRISMA-ScR guidelines. The topic was hypertension management in PD in the pediatric population. Studies within the last 10 years that were written in English were included to capture the latest advancements in the literature. Six articles were included in the review.ResultsThe included articles illustrated 3 main management strategies, which were diet, fluid volume, and antihypertensive drugs. More specifically, an inverse relationship between vitamin D and cholesterol levels and a lack of correlation between simple salt balance and hypertension have been described. Bioimpedance spectroscopy and B-type natriuretic peptide were found to be useful in the estimation of fluid volume. Additionally, the persistence of hypertension was found despite the use of antihypertensive drugs.ConclusionsThe presenting studies reflect the uncertainty of the current evidence available on hypertensive treatments in this population. Thus, our findings may help guide further research until the evidence is sufficient for clinical recommendations.</p>","PeriodicalId":19969,"journal":{"name":"Peritoneal Dialysis International","volume":" ","pages":"8968608261447433"},"PeriodicalIF":3.7,"publicationDate":"2026-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147841535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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