Ana E Figueiredo, Josephine Sf Chow, Ilaria de Barbieri, Carlos Eduardo Poli-de-Figueiredo
{"title":"Use of the face mask in peritoneal dialysis: Analysis of an online survey on global practices.","authors":"Ana E Figueiredo, Josephine Sf Chow, Ilaria de Barbieri, Carlos Eduardo Poli-de-Figueiredo","doi":"10.1177/08968608261497319","DOIUrl":"https://doi.org/10.1177/08968608261497319","url":null,"abstract":"<p><p>Peritoneal dialysis (PD) is an established home-based therapy. Face masks have historically been used as an infection-prevention measure during PD exchanges, although their effectiveness remains uncertain. Current evidence emphasizes hand hygiene and aseptic technique, while the incremental benefit of routine face mask use has not been clearly established. We conducted a cross-sectional online survey of PD nurses and nephrologists to describe clinical practices regarding face mask use during PD exchanges. Participants were recruited through professional networks and international professional organizations. The survey included questions regarding patient and healthcare professional mask use, institutional guidance, patient training, and perceptions of effectiveness. A total of 733 healthcare professionals from 71 countries responded, including 617 nurses (84.2%). Face masks were reported to be always used by patients during bag exchanges or connection to the cycler by 72.3% (n = 530) of respondents. The most frequently reported reason for mask use was general infection prevention (40.9%, n = 299). Mask use was included in patient training by 80.2% (n = 588), and 77.6% (n = 567) believed that mask use helps prevent peritonitis. Significant regional differences were observed in reported mask-use practices (χ<sup>2</sup> = 44.65, df = 8, p < 0.001). Mask use also varied according to PD program size (χ<sup>2</sup> = 20.06, df = 6, p = 0.003). In addition, 39.6% (n = 290) reported that their facility followed specific guidance regarding mask use. Routine face mask use remains common in PD practice and is widely incorporated into patient training. Substantial regional and program-size variation was observed. Given the limited and uncertain evidence regarding the incremental benefit of routine mask use, these findings describe substantial variation in current practice and highlight the need for further evidence to clarify the role of face masks in PD infection prevention.</p>","PeriodicalId":19969,"journal":{"name":"Peritoneal Dialysis International","volume":" ","pages":"8968608261497319"},"PeriodicalIF":1.8,"publicationDate":"2026-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149220560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Arunima Jain, Matthew Rowlandson, Eric Au, Sradha Kotwal, David W Johnson, Kamal Sud, Katrina Chau, Ashik Hayat, Monique Borlace, Melinda Tomlins, Dana Forcey, Yeoungjee Cho, Jenny Hc Chen, Neil Boudville
{"title":"Temporal association of peritoneal dialysis-associated peritonitis rates and outcomes with COVID-19 pandemic onset in Australia: A registry analysis.","authors":"Arunima Jain, Matthew Rowlandson, Eric Au, Sradha Kotwal, David W Johnson, Kamal Sud, Katrina Chau, Ashik Hayat, Monique Borlace, Melinda Tomlins, Dana Forcey, Yeoungjee Cho, Jenny Hc Chen, Neil Boudville","doi":"10.1177/08968608261469965","DOIUrl":"https://doi.org/10.1177/08968608261469965","url":null,"abstract":"<p><p>BackgroundEffective infection control practices are recommended to prevent peritoneal dialysis-associated peritonitis (PD peritonitis). Effects of the coronavirus 2019 (COVID-19) pandemic and preventive measures on PD peritonitis outcomes are unclear.MethodsUsing the Australia and New Zealand Dialysis and Transplant (ANZDATA) Registry data, we assessed PD peritonitis rates and outcomes in Australia before and after COVID-19 pandemic onset, defined using the World Health Organisation pandemic date (11/03/2020), between 01/01/2015 and 31/12/2022. PD peritonitis rates, trends (using interrupted time series and joinpoint regression analysis) and outcomes were analysed in prevalent patients on PD. Incident and prevalent patient characteristics commencing PD were analysed.ResultsIn prevalent PD patients (<i>n</i> = 11,499), peritonitis rates were lower post-COVID-19 (0.30 episodes per patient-year, 95% confidence interval [CI]: 0.29-0.31) than in the pre-COVID-19 period (0.35, 95% CI: 0.34-0.36, <i>p</i> < 0.001). PD peritonitis rates were declining prior to COVID-19 (incident rate ratio [IRR] per half-year = 0.97, 95% CI 0.96-0.98, <i>p</i> < 0.001), with a relative increase after COVID-19 onset (IRR = 1.05; 95% CI: 1.00-1.09, <i>p</i> = 0.049).There were increases in odds of PD peritonitis relapse (adjusted odds ratio (aOR): 1.41, 95% CI: 1.14-1.76) and recurrence (aOR: 1.45, 95% CI: 1.13-1.86) post-COVID-19.A total of 8999 incident patients started PD during the study period, 5763 pre-COVID-19 and 3236 post-COVID-19. Patient characteristics were similar between groups, other than rates of smoking, cerebrovascular disease and PD modality.ConclusionsPD peritonitis rates have been declining in Australia, with a modest relative increase in peritonitis rates post-COVID-19 onset. Odds of PD peritonitis relapse and recurrence were higher post-COVID-19, highlighting the need for further research regarding PD practices post-pandemic.</p>","PeriodicalId":19969,"journal":{"name":"Peritoneal Dialysis International","volume":" ","pages":"8968608261469965"},"PeriodicalIF":1.8,"publicationDate":"2026-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149147803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Niakhaleen Keita, Niokhor Diaw, Ahmed Tall Lemrabott, Moustapha Faye, Ibrahima Sow, Fatou Ndiaye, Bacary Ba, Maria Faye, Fatou Gueye, Mame Awa Diop, Mansour Mbengue, Abdou Niang, El Hadji Fary Ka
{"title":"Long-term clinical outcomes of peritoneal dialysis patients: analysis of the Senegalese cohort from 2004 to 2020.","authors":"Niakhaleen Keita, Niokhor Diaw, Ahmed Tall Lemrabott, Moustapha Faye, Ibrahima Sow, Fatou Ndiaye, Bacary Ba, Maria Faye, Fatou Gueye, Mame Awa Diop, Mansour Mbengue, Abdou Niang, El Hadji Fary Ka","doi":"10.1177/08968608261493211","DOIUrl":"https://doi.org/10.1177/08968608261493211","url":null,"abstract":"<p><p>BackgroundPeritoneal dialysis (PD) was introduced in Senegal in 2003, with the first PD center established at Aristide Le Dantec University Hospital. Our study aims to determine long-term outcomes of the Senegalese PD cohort.MethodsWe performed a single-center retrospective cohort study of adults patients treated with chronic PD from 2004 to 2020. Demographics, comorbidities, labs, complications, hemodialysis (HD) transfers, hospitalizations, PD discontinuation and mortality were collected. Survival was assessed using Kaplan-Meier and Cox models.ResultsDuring the study period, 232 patients were treated by PD. The mean age was 47.5 ± 14.9 years, 56.9% were female, 76% lacked health insurance, and 98.3% had hypertension. Median distance to the PD unit was 22 km (IQR: 13-100). Most patients started kidney replacement therapy on HD in private sector and were transferred to PD due to financial constraints (out-of-pocket payment). A total of 351 peritonitis episodes occurred in 174 patients (0.97 episodes per patient-year), including 14.9% experienced more than three episodes. <i>Staphylococcus aureus</i> and <i>Pseudomonas</i> species were the most frequent causative organisms, with 35.9% of culture-negative episodes. Permanent transfer to HD was the leading cause of PD discontinuation (59.6%), followed by death (37.7%). Median patient survival was 31 months. Time on PD therapy had a median of 35 months, with one-, three-, and five-year survival of 86.1%, 49.8%, and 25.3%, respectively, censored for death, kidney transplantation, and recovery of renal function.ConclusionsPD in Senegal is suitable but challenged by infectious, mechanical, metabolic complications and socioeconomic barriers. Improving infection control, monitoring, catheter placement, and insurance coverage is key to expanding equitable dialysis access.</p>","PeriodicalId":19969,"journal":{"name":"Peritoneal Dialysis International","volume":" ","pages":"8968608261493211"},"PeriodicalIF":1.8,"publicationDate":"2026-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149137864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Wai Lun Will Pak, Desmond Yat Hin Yap, Shui Kuen Cheng, Sandy Ka Yee Chau, Chi Kwan Lam, Sze Ho Sunny Wong
{"title":"<i>Stenotrophomonas maltophilia</i> peritoneal dialysis-related peritonitis: A 20-year single-centre retrospective review.","authors":"Wai Lun Will Pak, Desmond Yat Hin Yap, Shui Kuen Cheng, Sandy Ka Yee Chau, Chi Kwan Lam, Sze Ho Sunny Wong","doi":"10.1177/08968608261493212","DOIUrl":"https://doi.org/10.1177/08968608261493212","url":null,"abstract":"<p><p>BackgroundPeritoneal dialysis (PD)-related peritonitis due to <i>Stenotrophomonas maltophilia</i> presents significant challenges in clinical management due to its multi-drug resistance and tendency to form biofilms. Published data on its clinical epidemiology and outcomes remain limited.MethodsWe retrospectively reviewed all <i>S. maltophilia</i> PD-peritonitis at a regional PD centre in Hong Kong from April 2005 to March 2025. Patient characteristics, antimicrobial sensitivity and resistance patterns, treatments, and outcomes were analysed.ResultsWe identified 28 <i>S. maltophilia</i> peritonitis episodes in 27 patients during the study period, accounting for 0.96% of all peritonitis episodes. Nineteen (70.4%) patients had medical comorbidities suggesting immunocompromised states in addition to chronic kidney disease; most episodes occurred after hospitalization (64.3%) or antibiotic use (57.1%). While most initial isolates were susceptible to trimethoprim-sulfamethoxazole (100%), levofloxacin (96.3%), and minocycline (100%), later emergence of less susceptible isolates was common (42.9%). Six episodes (21.4%) achieved medical cure but 9 (32.1%) showed relapsing peritonitis. Fifteen (53.6%) experienced PD catheter removal while 12 (42.9%) required transfer to haemodialysis. Eight (28.6%) had peritonitis-associated death.ConclusionThis is the largest case series of <i>S. maltophilia</i> PD-peritonitis to date. <i>S. maltophilia</i> was an uncommon cause of PD-peritonitis but conferred substantial adverse outcomes. Early identification of <i>S. maltophilia</i> and sufficient duration of appropriate antimicrobials may help achieve better outlook.</p>","PeriodicalId":19969,"journal":{"name":"Peritoneal Dialysis International","volume":" ","pages":"8968608261493212"},"PeriodicalIF":1.8,"publicationDate":"2026-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149137923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Silvio Borrelli, Valentina Masola, Tommaso Prosdocimi, Richard Corbett, Francesco Trepiccione, Lorenzo Di Liberato, Mario Bonomini, Gaetano La Manna, Giacomo Magnoni, Luca Nardelli, Giuseppe Castellano, Giuseppe Paribello, Federica Marzano, Luciano D'Apolito, Sarah Lawman, Valerio Vizzardi, Gianpaolo Reboldi, Josè Carolino Divino-Filho, Giovambattista Capasso, Massimo Iacobelli, Arduino Arduini
{"title":"PolyCore, a bimodal peritoneal dialysis solution based on xylitol, L-carnitine, and icodextrin: In vitro evidence of the peritoneal membrane protection, rationale, and design of the phase II pilot study EXCITE.","authors":"Silvio Borrelli, Valentina Masola, Tommaso Prosdocimi, Richard Corbett, Francesco Trepiccione, Lorenzo Di Liberato, Mario Bonomini, Gaetano La Manna, Giacomo Magnoni, Luca Nardelli, Giuseppe Castellano, Giuseppe Paribello, Federica Marzano, Luciano D'Apolito, Sarah Lawman, Valerio Vizzardi, Gianpaolo Reboldi, Josè Carolino Divino-Filho, Giovambattista Capasso, Massimo Iacobelli, Arduino Arduini","doi":"10.1177/08968608261493817","DOIUrl":"https://doi.org/10.1177/08968608261493817","url":null,"abstract":"<p><p>BackgroundGlucose exposure in peritoneal dialysis contributes to local peritoneal membrane injury and systemic metabolic complications. The osmo-metabolic approach seeks to reduce glucose burden by using alternative osmotic agents such as xylitol and L-carnitine. PolyCore is a novel glucose-free bimodal peritoneal dialysis solution combining icodextrin (4%), xylitol (1.5%), and L-carnitine (0.02%), designed to provide sustained ultrafiltration while improving biocompatibility.MethodsHuman peritoneal mesothelial cells were exposed to PolyCore, icodextrin 7.5% solution, or a control medium. Cell viability, transepithelial electrical resistance, fibrosis-related gene expression, and α-SMA (alpha-smooth muscle actin) protein expression were assessed. In parallel, the EXCITE study was designed as a phase II, single-arm, prospective pilot trial evaluating PolyCore in 28 adults with end-stage kidney disease receiving incremental peritoneal dialysis.ResultsPolyCore preserved mesothelial cell viability and barrier integrity, with transepithelial resistance values comparable to control and significantly higher than icodextrin 7.5%. Compared with icodextrin 7.5%, PolyCore showed a more favorable expression profile of mesothelial-to-mesenchymal transition markers, with lower α-SMA and vimentin and preserved E-cadherin. The EXCITE study will assess safety and preliminary efficacy, including dialysis adequacy, ultrafiltration, solute removal, metabolic parameters, and patient-reported outcomes.ConclusionsPolyCore showed favorable in vitro biocompatibility compared with standard icodextrin 7.5% and may represent a glucose-free bimodal strategy for peritoneal dialysis. EXCITE will provide first clinical assessment on the safety and preliminary efficacy of PolyCore.</p>","PeriodicalId":19969,"journal":{"name":"Peritoneal Dialysis International","volume":" ","pages":"8968608261493817"},"PeriodicalIF":1.8,"publicationDate":"2026-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149137926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lu Dai, Giedre Martus, Jan Dominik Kampmann, Helga Gudmundsdottir, Jonna Virtanen, Sadollah Abedini, Markus Björksten, Kate McCarthy, Peter Rutherford, Kristien Daenen, Tommy Aronsen
{"title":"Standardizing the digital frontier: A Nordic survey of remote patient management practice patterns and variations in peritoneal dialysis care.","authors":"Lu Dai, Giedre Martus, Jan Dominik Kampmann, Helga Gudmundsdottir, Jonna Virtanen, Sadollah Abedini, Markus Björksten, Kate McCarthy, Peter Rutherford, Kristien Daenen, Tommy Aronsen","doi":"10.1177/08968608261488692","DOIUrl":"https://doi.org/10.1177/08968608261488692","url":null,"abstract":"<p><p>BackgroundRemote patient management (RPM) improves automated peritoneal dialysis (APD) care safety and efficiency, yet the detailed clinical pathway of its utilization remains variable. We investigated digital practice patterns, healthcare professional (HCP) perceptions, and potential gaps for RPMAPD implementation across peritoneal dialysis (PD) clinics in the Nordic countries.MethodsHCPs across 85 Nordic PD clinics were surveyed to evaluate the perceived clinical value, adoption importance, and specific practice patterns of RPM utilization.ResultsA total of 60 participants completed the survey, and 93.3% recognized the value of RPM for early identification of ultrafiltration deficits and catheter-related complications. Thirty-five percent of respondents reported the absence of standardized RPM protocols, and 20% were unaware of any existing protocol. Patterns of RPM utilization varied: while 61.7% reported that both physicians and nurses had access to RPM platforms, 65% of PD nurses reviewed RPM data at least twice a week, and 81% of physicians only reviewed data during regular patient visits or did not review the data at all. Among physicians, 38% reported routinely showing RPM data to patients during clinic visits, and 19% never showed the data. Despite the inconsistency of RPM utilization, 63% of respondents considered developing standardized RPM protocols to be very or extremely important, and 65% expressed interest in optimizing RPM implementation and clinical integration.ConclusionsThe clinical value of RPMAPD was well recognized among Nordic HCPs; however, its implementation remained inconsistent, and physician engagement in routine use of remote monitoring (RM) tools appeared limited. Standardized protocols and consistent training were deemed essential to optimize RM in routine PD practice.</p>","PeriodicalId":19969,"journal":{"name":"Peritoneal Dialysis International","volume":" ","pages":"8968608261488692"},"PeriodicalIF":1.8,"publicationDate":"2026-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148991087","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shannon Ejiofor, Mowaffaq Said, Manar Shmais, Kana N Miyata
{"title":"Peritoneal dialysis in Crohn's disease: A gray area worth revisiting.","authors":"Shannon Ejiofor, Mowaffaq Said, Manar Shmais, Kana N Miyata","doi":"10.1177/08968608261488695","DOIUrl":"https://doi.org/10.1177/08968608261488695","url":null,"abstract":"<p><p>Crohn's disease (CD) has traditionally been considered a relative or absolute contraindication to peritoneal dialysis (PD) because of concerns regarding chronic inflammation, peritoneal membrane injury, adhesions, and increased risk of peritonitis. However, clinical evidence supporting these concerns remains sparse. We report two patients with CD who initiated PD with differing outcomes. A 46-year-old man with longstanding stricturing ileocolonic CD developed end-stage kidney disease (ESKD) from monoclonal gammopathy of renal significance and acute interstitial nephritis. His CD was in clinical and endoscopic remission at PD initiation. He successfully continued PD without episodes of peritonitis or catheter-related complications until kidney transplantation 7 months later. In contrast, a 27-year-old man with ileal CD and ESKD from IgA nephropathy developed immediate PD catheter outflow failure. His prior CD therapies included multiple biologic agents, all without sustained remission, although endoscopic remission was eventually achieved. Despite laparoscopic intervention, catheter malfunction persisted, leading to catheter removal and transition to hemodialysis. These cases illustrate that PD may be feasible in selected patients with CD, particularly those with sustained clinical remission, and that the role of PD in this population may warrant re-evaluation.</p>","PeriodicalId":19969,"journal":{"name":"Peritoneal Dialysis International","volume":" ","pages":"8968608261488695"},"PeriodicalIF":1.8,"publicationDate":"2026-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148945346","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Percutaneous peritoneal dialysis catheter making its way to the prevertebral space: A rare occurrence.","authors":"Sunil Kumar Behera, Anish Saha, Vinay Rathore, Narendra Kuber Bodhey, Yeshwanth Mohan Yelavarthy","doi":"10.1177/08968608261485134","DOIUrl":"https://doi.org/10.1177/08968608261485134","url":null,"abstract":"<p><p>Percutaneous peritoneal dialysis (PD) catheter insertion is widely performed by nephrologists and is generally safe; however, a lack of direct visualization may predispose to mechanical complications, including catheter malposition. We report a rare case of PD catheter migration into the retroperitoneal prevertebral space. A 33-year-old woman with chronic kidney disease stage 5 secondary to chronic glomerulonephritis underwent ultrasound-guided percutaneous Tenckhoff catheter insertion for initiation of continuous ambulatory PD. Although inflow was adequate, persistent outflow dysfunction prompted further evaluation. Imaging revealed that the catheter had traversed the posterior peritoneal wall and entered the prevertebral space anterior to the L5 vertebra. Laparoscopy confirmed the finding, and the catheter was successfully repositioned into the pelvis with closure of the peritoneal defect. The patient subsequently initiated PD with satisfactory catheter function. This case highlights an extremely rare catheter malposition and underscores the importance of early imaging and multidisciplinary management to salvage catheter function.</p>","PeriodicalId":19969,"journal":{"name":"Peritoneal Dialysis International","volume":" ","pages":"8968608261485134"},"PeriodicalIF":1.8,"publicationDate":"2026-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148906646","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Parth I Kumar, Jennifer Woo, Neeraja Kambham, Glenn M Chertow
{"title":"Calcified amorphous tumor in a patient receiving peritoneal dialysis with severe, treatment-refractory hyperphosphatemia.","authors":"Parth I Kumar, Jennifer Woo, Neeraja Kambham, Glenn M Chertow","doi":"10.1177/08968608261479962","DOIUrl":"https://doi.org/10.1177/08968608261479962","url":null,"abstract":"<p><p>Calcified amorphous tumors (CATs) are rare, non-neoplastic intracardiac masses first described by Reynolds et al. in 1997. Although increasingly reported, their pathogenesis remains poorly understood, and they are frequently misdiagnosed as vegetations, cardiac myxomas, or malignant tumors. Proposed mechanisms include abnormalities in calcium-phosphate metabolism and hypercoagulable states. We report a case of CAT formation in a patient receiving peritoneal dialysis with severe, refractory hyperphosphatemia. A 47-year-old woman with type 2 diabetes mellitus, hypertension, heart failure with reduced ejection fraction, and end-stage renal disease on peritoneal dialysis had unremitting hyperphosphatemia (>10 mg/dL). Phosphate control was limited despite having trialed sevelamer and calcium acetate and intolerance to tenapanor due to gastrointestinal adverse effects. She had mixed adherence to dietary recommendations. She presented with leg pain and imaging raised concern for a psoas abscess. As part of an infectious embolic evaluation, transthoracic echocardiography revealed mitral valve dysfunction caused by a mobile intracardiac mass. Surgical resection was performed, and histopathologic examination confirmed a CAT. CATs typically present with symptoms related to valvular obstruction or embolization. Imaging findings on echocardiography, computed tomography, or magnetic resonance imaging are nonspecific, making histopathology essential for definitive diagnosis. Surgical excision remains the treatment of choice, with recurrence reported rarely. Given the propensity for calcium-phosphate deposition in patients with chronic hyperphosphatemia, strict phosphate control may reduce the risk of CAT development in patients with end-stage renal disease, though further studies are needed to clarify preventive strategies.</p>","PeriodicalId":19969,"journal":{"name":"Peritoneal Dialysis International","volume":" ","pages":"8968608261479962"},"PeriodicalIF":1.8,"publicationDate":"2026-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148888341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}