{"title":"Association Between Circadian Rhythm Syndrome and Physical Pain in China.","authors":"Xiaojing Feng, Fengdan Wang, Shangning Wu, Sitong Xin, Xiaotong Li, Ying Zhu, Shufei Li, Zihan Meng, Hongyue Chen, Yang Yang, Bo Li, Shanshan Xu","doi":"10.1016/j.pmn.2026.09.021","DOIUrl":"https://doi.org/10.1016/j.pmn.2026.09.021","url":null,"abstract":"<p><strong>Purpose: </strong>Circadian rhythm syndrome (CircS) is a complex syndrome caused by biological rhythm disruption and is closely associated with the onset of numerous diseases. This study aimed to explore the association between CircS and physical pain, providing important clues and a scientific basis for the development of pain prevention strategies.</p><p><strong>Design: </strong>A retrospective cohort study was conducted using data from the 2011-2018 China Health and Retirement Longitudinal Study (CHARLS).</p><p><strong>Methods: </strong>The association between CircS and the risk of developing physical pain was analyzed using Kaplan-Meier survival curves and Cox proportional hazards models. Restricted Cubic Splines (RCS) were employed to examine linear or nonlinear relationships between the number of CircS components and the risk of physical pain events. Assessed the robustness of the results using sensitivity analyses, such as subgroup analyses and interaction analyses.</p><p><strong>Results: </strong>The longitudinal study included 5,388 participants, of whom 3,296 experienced pain events during follow-up. Results indicated that participants with CircS had a higher risk of physical pain than those without CircS (hazard ratio: 1.203, 95% confidence interval: 1.113, 1.300, p < .001). Interaction analysis demonstrated that CircS, smoking, and active social participation exhibited a significant interaction in their effects on physical pain.</p><p><strong>Conclusions: </strong>CircS increased the risk of developing physical pain. Addressing circadian rhythm disorders and maintaining metabolic homeostasis were crucial for preventing and delaying the onset of physical pain.</p><p><strong>Clinical implications: </strong>This study provides important clues and a scientific basis for the clinical application of \"circadian rhythm-pain\" management.</p>","PeriodicalId":19959,"journal":{"name":"Pain Management Nursing","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149245947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effects of Different Exercise Modalities on Chemotherapy-Induced Peripheral Neuropathy in Breast Cancer Patients.","authors":"Zengyu Wang, Xiaoxiao Wu, Yongqing Shen, Hui Liu, Xin Xu, Jialu Kang, Qi Wang, Wei Liu","doi":"10.1016/j.pmn.2026.09.005","DOIUrl":"https://doi.org/10.1016/j.pmn.2026.09.005","url":null,"abstract":"<p><strong>Purpose: </strong>To investigate effects of different exercise modalities on chemotherapy‑induced peripheral neuropathy (CIPN) and quality of life in breast cancer patients, and identify the optimal exercise rehabilitation protocol.</p><p><strong>Design: </strong>This study is a single-center randomized controlled trial.</p><p><strong>Methods: </strong>This randomized controlled trial enrolled 68 breast cancer patients with CIPN, randomly assigning them to a control group, aerobic exercise group, resistance training group, and combined exercise group for an 8-week intervention. Outcomes included foot vibration perception, lower limb muscle strength, and quality of life.</p><p><strong>Results: </strong>After 8 weeks of intervention, both aerobic exercise and resistance training significantly improved CIPN symptoms (p < .05). Regarding lower limb muscle strength, resistance training and combined exercise significantly outperformed the control group and aerobic exercise group (p < .05). Regarding quality of life, combined exercise outperformed other groups (p < .05). All exercise interventions demonstrated superiority over the control group in emotional function and insomnia (p < .05). No significant changes in vibration perception were observed across any group (p > .05).</p><p><strong>Conclusions: </strong>Exercise therapy is safe and effective in relieving symptoms, enhancing muscle strength, and improving quality of life, with combined exercise showing optimal effects for clinical application.</p><p><strong>Clinical implication: </strong>This study offers references for clinical nonpharmacological rehabilitation of CIPN. Tailored combined aerobicresistance exercise may be considered. Integrating subjective scales with objective functional indicators and monitoring lymphedema risks helps formulate holistic rehabilitation strategies.</p>","PeriodicalId":19959,"journal":{"name":"Pain Management Nursing","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149245899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lisa R Carnago, Dan V Blalock, William C Becker, Pooja Lagisetty, Hayden B Bosworth, Allison A Lewinski, Kelli D Allen
{"title":"Rebalancing Opioid Guidance: Toward Patient-Centered Pain Management Across the Care Continuum.","authors":"Lisa R Carnago, Dan V Blalock, William C Becker, Pooja Lagisetty, Hayden B Bosworth, Allison A Lewinski, Kelli D Allen","doi":"10.1016/j.pmn.2026.10.006","DOIUrl":"https://doi.org/10.1016/j.pmn.2026.10.006","url":null,"abstract":"","PeriodicalId":19959,"journal":{"name":"Pain Management Nursing","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149183544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Miquel Anguela-Maydeu, Bilal El Hamdouni, Angel Belzunegui-Eraso, Marina Gómez de Quero-Córdoba, Eva de Mingo-Fernández, María Jiménez-Herrera
{"title":"Nurse-Led Music Listening During Chemotherapy: A Prepost Study.","authors":"Miquel Anguela-Maydeu, Bilal El Hamdouni, Angel Belzunegui-Eraso, Marina Gómez de Quero-Córdoba, Eva de Mingo-Fernández, María Jiménez-Herrera","doi":"10.1016/j.pmn.2026.09.008","DOIUrl":"https://doi.org/10.1016/j.pmn.2026.09.008","url":null,"abstract":"<p><strong>Purpose: </strong>Emotional distress and pain are highly prevalent among patients undergoing chemotherapy and negatively affect treatment tolerance and quality of life. Receptive music listening has emerged as a safe complementary intervention in oncology care, although evidence from nurse-led implementations in routine clinical settings remains limited. This study aimed to evaluate the immediate effects of a brief nurse-led receptive music listening intervention delivered during chemotherapy infusion on mood, relaxation, and pain.</p><p><strong>Design: </strong>Quasi-experimental pre-post evaluation with a single group.</p><p><strong>Methods: </strong>A convenience sample of 34 adult oncology patients receiving chemotherapy in two public hospitals in Catalonia, Spain, participated in a single, individualised receptive music listening session during treatment administration. Outcomes were assessed immediately before and after the intervention using visual analogue scales for mood, relaxation, and pain. Paired statistical tests were applied as appropriate, and effect sizes were calculated.</p><p><strong>Results: </strong>Statistically significant improvements were observed in mood, relaxation, and pain following the intervention. Mood and relaxation scores increased, while perceived pain decreased after the receptive music listening session. Effect sizes ranged from moderate to large, suggesting potentially relevant immediate changes. All participants completed the intervention and assessments, and no adverse events were reported.</p><p><strong>Conclusions: </strong>A brief nurse-led receptive music listening intervention delivered during chemotherapy was associated with immediate improvements in emotional and physical wellbeing. The intervention was feasible and well accepted.</p><p><strong>Clinical implications: </strong>Receptive music listening can be easily integrated into routine oncology nursing practice and may represent a simple, low-risk, person-centred supportive intervention during chemotherapy.</p>","PeriodicalId":19959,"journal":{"name":"Pain Management Nursing","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149147977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Patient Activation is Associated With Positive Attitudes Toward Pain Medications.","authors":"Ji Won Lee, Janiece L Taylor, Richard L Skolasky","doi":"10.1016/j.pmn.2026.09.002","DOIUrl":"https://doi.org/10.1016/j.pmn.2026.09.002","url":null,"abstract":"<p><strong>Purpose: </strong>To examine the associations between patient activation and pain-medication attitudes and long-term opioid use among patients with chronic low back pain (cLBP).</p><p><strong>Design: </strong>Cross-sectional study with longitudinal follow-up.</p><p><strong>Methods: </strong>We surveyed participants at 30 days, 3 months, 6 months, and 12 months. The survey included the Patient Activation Measure, Short Barriers Questionnaire-Taiwan (pain-medication attitudes), Oswestry Disability Index (ODI) (pain-related disability), and long-term opioid use.</p><p><strong>Results: </strong>A total of 1,055 patients was included in the main analysis. Patients in the low-activation group were more likely to report opioid use within 30 days and at 3 months and to endorse greater pain-related disability. Patients with high activation were more likely than patients with low activation to disagree with the beliefs that pain medication cannot control their pain, that good patients avoid talking about pain, and that pain medication should be saved.</p><p><strong>Conclusions: </strong>High patient activation was associated with decreasing short- and long-term opioid use and less maladaptive attitudes toward pain medications. Participants with long-term opioid use were more likely to have maladaptive attitudes toward pain medications. Interventions that deploy multi-modal nonpharmacological or psychosocial approaches (e.g., motivational interviewing), in addition to collaboratively setting goals, managing expectations, and improving medication knowledge, are needed to improve patient activation among patients with cLBP.</p><p><strong>Implications for nursing education, practice, and research: </strong>Motivational interviewing, collaborative goal setting, and improving medication knowledge and managing pain expectations may help improve activation in this population.</p>","PeriodicalId":19959,"journal":{"name":"Pain Management Nursing","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149148015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"An Explainable AI-Guided Framework for Cancer Pain Phenotyping and Clinical Decision-Making.","authors":"Heba Khalil, Abedalmajeed Shajrawi, Wegdan Bani-Issa, Fatma Refaat Ahmed, Alham Al-Sharman, Dilber Uzun Ozsahin, Declan Ikechukwu Emegano, Nabeel Al-Yateem","doi":"10.1016/j.pmn.2026.09.016","DOIUrl":"https://doi.org/10.1016/j.pmn.2026.09.016","url":null,"abstract":"<p><strong>Purpose: </strong>Current pain management often relies primarily on pain intensity, which may not capture patient variability or guide individualized care. Advances in machine learning (ML) and explainable artificial intelligence (XAI) offer opportunities to improve assessment by identifying clinically meaningful subgroups and enhancing model interpretability. This study aimed to identify distinct cancer pain phenotypes using explainable machine learning and to develop a phenotype-guided clinical decision framework to support individualized pain assessment and management.</p><p><strong>Design: </strong>A cross-sectional study.</p><p><strong>Methods: </strong>Data from 260 cancer patients was analyzed using ML to identify distinct pain phenotypes. Variables included pain intensity, catastrophizing, psychological distress, quality of life, and self-management strategies. Three ML models, Extreme Gradient Boosting (XGB), Light Gradient Boosting Machine (LGBM), and Categorical Boosting (CatBoost), were evaluated using accuracy, precision, recall, and F1 score. Two XAI methods, SHapley Additive exPlanations (SHAP) and Local Interpretable Model-Agnostic Explanations (LIME), were applied to enhance model transparency and identify key predictors of phenotype classification.</p><p><strong>Results: </strong>Four cancer pain phenotypes were identified: High-Burden Pain, Catastrophizing-Dominant, Stress-Related Pain, and Low-Risk Adaptive. CatBoost achieved the highest performance (accuracy = 0.98; F1 score = 0.97). SHAP analysis indicated that pain catastrophizing and psychological distress were the strongest predictors, whereas pain intensity contributed less. LIME analyses confirmed that individual predictions were primarily driven by cognitive and emotional factors. A phenotype-guided clinical decision framework was developed to align patient profiles with targeted interventions.</p><p><strong>Conclusion: </strong>Integrating ML and XAI into cancer pain assessment provides clinically interpretable insights into multidimensional patient profiles. The identified phenotypes and proposed framework support personalized, mechanism-based pain management. Incorporating psychological and behavioral dimensions into routine assessment may improve clinical decision-making and patient outcomes.</p><p><strong>Clinical implication: </strong>Identifying distinct pain phenotypes may support individualized pain assessment and management by helping healthcare professionals recognize patient subgroups with different pain characteristics and treatment needs.</p>","PeriodicalId":19959,"journal":{"name":"Pain Management Nursing","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149137951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Stijn J M Temmink, Christina Bode, Peter M Ten Klooster, Harald E Vonkeman
{"title":"The Effects, Usability and User Satisfaction of Virtual Reality for People With Chronic Musculoskeletal Pain: A Scoping Review.","authors":"Stijn J M Temmink, Christina Bode, Peter M Ten Klooster, Harald E Vonkeman","doi":"10.1016/j.pmn.2026.09.015","DOIUrl":"https://doi.org/10.1016/j.pmn.2026.09.015","url":null,"abstract":"<p><strong>Objective: </strong>To review the existing evidence of the effectiveness, usability, and user satisfaction of virtual reality on chronic musculoskeletal pain.</p><p><strong>Design: </strong>A scoping review based on PRISMA-ScR guidelines. Data sources Four electronic databases were used: MEDLINE, Scopus, CINAHL, and PsycINFO.</p><p><strong>Review/analysis methods: </strong>All articles were screened by a single reviewer, with a second reviewer randomly screening 10% of the articles to verify consistency. Data was tabulated and synthesized.</p><p><strong>Results: </strong>Eleven studies were included for review, including randomized controlled trials and case studies. Seven studies were conducted among patients with chronic low back pain. Five studies used virtual reality programs based on psychotherapeutic approaches, of which most reported a reduction in pain intensity due to virtual reality use. Other types of virtual reality programs, such as embodiment-based and exercise-based, were more variable in terms of effectiveness. User satisfaction differed across intervention types, with psychotherapy-based VR most often reported as satisfactory.</p><p><strong>Conclusions: </strong>Current literature suggests that psychotherapy-based VR interventions are most consistently associated with reported reductions in pain intensity in people with chronic MSK pain. However, findings predominantly focus on chronic low back pain populations, limiting generalizability to other MSK conditions. Further research is needed to explore the application of VR interventions across a broader range of chronic MSK pain conditions and to consistently report outcomes related to usability and user satisfaction. Nursing Practice Implications VR shows potential as an at-home self-management tool for chronic MSK pain reduction, particularly low back pain. Selecting evidence-based, tailored programs may increase treatment effectiveness and use.</p>","PeriodicalId":19959,"journal":{"name":"Pain Management Nursing","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149137917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comparison of Two Scales for Assessing Procedural Pain During a Bed Bath.","authors":"Júlio César Dos Santos, Marisa Dibbern Lopes Correia, Caroline de Castro Moura, Luciene Muniz Braga, Katiusse Rezende Alves, Danielly Alves Ladislau, Luana Vieira Toledo","doi":"10.1016/j.pmn.2026.09.018","DOIUrl":"https://doi.org/10.1016/j.pmn.2026.09.018","url":null,"abstract":"<p><strong>Objectives: </strong>To compare pain intensity during bed bathing in mechanically ventilated critically ill adults using the Behavioral Pain Scale (BPS) and the Critical-Care Pain Observation Tool (CPOT).</p><p><strong>Design: </strong>This prospective observational repeated-measures study.</p><p><strong>Methods: </strong>This study monitored 65 bed baths. Pain was assessed with the BPS and CPOT before the bath, 5 minutes after initiation, during patient lateralization, immediately after completion, and 15 minutes after completion. Friedman and Wilcoxon tests compared scores across time points, and Spearman's coefficient assessed correlations between scales. Statistical significance was set at p < .05.</p><p><strong>Results: </strong>The study included 28 participants and 65 observed bed baths. Median age was 78.5 years, and 42.9% were male. Mean bath duration was 15 minutes and 35 seconds. BPS and CPOT scores were strongly correlated (rs = 0.837-0.894, all p < .001). Cluster-adjusted models confirmed higher pain scores during the procedure than before bathing.</p><p><strong>Conclusion: </strong>Bed bathing produced mild, transient procedural pain, particularly during patient manipulation.</p><p><strong>Clinical implications: </strong>Both scales may support routine pain surveillance in mechanically ventilated ICU patients; selection should consider local workflow, staff training, and the need for applicability across intubated and extubated patients.</p>","PeriodicalId":19959,"journal":{"name":"Pain Management Nursing","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149128389","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mauro Mota, Inês Prates, Ricardo J O Ferreira, Filipe Melo, Miguel Castelo-Branco, Fernando Gama, Madalena Cunha, Margarida Reis Santos
{"title":"Immobilization Discomfort During Prolonged Emergency Stretcher Use: An Exploratory Qualitative Descriptive Study.","authors":"Mauro Mota, Inês Prates, Ricardo J O Ferreira, Filipe Melo, Miguel Castelo-Branco, Fernando Gama, Madalena Cunha, Margarida Reis Santos","doi":"10.1016/j.pmn.2026.09.019","DOIUrl":"https://doi.org/10.1016/j.pmn.2026.09.019","url":null,"abstract":"<p><strong>Background: </strong>Accurate pain assessment in trauma care is challenged by the coexistence of multiple forms of discomfort. Recognizing and differentiating these experiences is essential to improve assessment accuracy and guide appropriate early interventions. However, immobilization discomfort remains poorly defined.</p><p><strong>Purpose: </strong>Explore the experiences of healthy volunteers subjected to immobilization on an ambulance stretcher, and develop a preliminary conceptual definition of immobilization discomfort.</p><p><strong>Design: </strong>Exploratory qualitative descriptive study.</p><p><strong>Method: </strong>This exploratory qualitative descriptive study involved healthy volunteers who participated in two 1-hour immobilization sessions using the same stretcher, with a resting interval of 2 weeks. Data collection was carried out through a structured questionnaire with sociodemographic data, closed questions (such as discomfort [numeric-rating scale], comparison of discomfort between sessions, body location of main discomfort) and open-ended questions to characterize discomfort. All qualitative responses were analyzed using Bardin's content analysis technique.</p><p><strong>Results: </strong>A total of 21 participants (mean age = 20.8 years; SD = 3.99; 76.2% female) were enrolled. Global discomfort was higher in Session 1 (6.9 ± 1.9 vs 6.3 ± 2.4), but the paired difference was not statistically significant (p = .168). Discomfort was most frequently localized in the occipital region, heels, and shoulders, often intensifying with time. Thematic analysis revealed nine main categories: immobility and feelings of claustrophobia; pressure points on bony prominences; temporal progression of discomfort often evolving into pain; distinction between discomfort and pain; habituation effect across sessions; psychological components such as anxiety, stress, and distraction; environmental factors including heat, restricted visibility, itching, and breathing difficulties; immediate relief upon release; and sensations of paresthesia, numbness, or tingling.</p><p><strong>Conclusion: </strong>Immobilization discomfort is a subjective, multidimensional experience involving physical, psychological, and environmental components, and is distinct from pain in most volunteers. A preliminary conceptual definition was formulated, which may serve as a foundation for improving patient assessment and care protocols in emergency and transport settings. The findings are preliminary and require validation in trauma populations before clinical generalization.</p><p><strong>Clinical implications: </strong>Prolonged immobilization on a stretcher can cause significant physical and psychological discomfort, a phenomenon not yet well characterized. Immobilization discomfort on a stretcher was characterized as a multidimensional experience involving physical, psychological, and environmental factors, distinct from pain.</p>","PeriodicalId":19959,"journal":{"name":"Pain Management Nursing","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149128339","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pilot Study of Comprehensive Sickle Cell Care Bundle During Acute Crisis Admissions.","authors":"Navneet Strickland","doi":"10.1016/j.pmn.2026.09.017","DOIUrl":"https://doi.org/10.1016/j.pmn.2026.09.017","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the implementation of a comprehensive nonpharmacological pain management care bundle and associated length of stay in an acute care setting, mean pain score, morphine milligram equivalents, and engagement with nonpharmacological interventions among adults hospitalized with sickle cell disease pain crisis.</p><p><strong>Methods: </strong>A single group, prepost pilot study involving a comprehensive care bundle was implemented on a single unit of an urban Midwestern hospital in December of 2024. The care bundle included the following caring-healing interventions: heat, pet therapy, massage, music listening, aromatherapy, authentic nursing presence, and referrals to spiritual care and nutrition services that the patient could select from. Average length of stay, average pain scores, first 24-hour total MME usage, and engagement with caring-healing interventions were derived from electronic medical records for adult patients with an admission before and after care bundle implementation.</p><p><strong>Results: </strong>Pre- and postimplementation data were collected for 17 patients from December 2024 to June 2025. The average length of stay increased from 4.64 to 4.94 days, while average pain scores decreased from 8.7 to 6.9. The number of patients receiving 10 or more caring-healing interventions rose from 5 to 14. While some patients evidenced a decrease in total MME in the first 24 hours, the overall change was not significant.</p><p><strong>Conclusions: </strong>Implementation of a nonpharmacologic care bundle was used in adults hospitalized for SCD pain crisis and their use was associated with lower average pain scores.</p><p><strong>Clinical implications: </strong>Pain management nurses can use care bundles in acute care settings. These bundles may support multimodal and individual pain management for patients with sickle cell disease. The role of pain management nurses involves teaching nurses at the bedside as well as patients before and after their procedures or acute crisis.</p>","PeriodicalId":19959,"journal":{"name":"Pain Management Nursing","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149113638","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}