Pakistan Journal of Medical Sciences最新文献

筛选
英文 中文
The impact of age on the survival outcomes of hepatocellular carcinoma patients after transarterial chemoembolization: A systematic review and meta-analysis. 年龄对肝细胞癌患者经动脉化疗栓塞后生存结果的影响:一项系统回顾和荟萃分析。
IF 1.2 4区 医学
Pakistan Journal of Medical Sciences Pub Date : 2025-04-01 DOI: 10.12669/pjms.41.4.11718
Xue Du, Xiaoting Zhang
{"title":"The impact of age on the survival outcomes of hepatocellular carcinoma patients after transarterial chemoembolization: A systematic review and meta-analysis.","authors":"Xue Du, Xiaoting Zhang","doi":"10.12669/pjms.41.4.11718","DOIUrl":"https://doi.org/10.12669/pjms.41.4.11718","url":null,"abstract":"<p><strong>Background & objective: </strong>The efficacy of transarterial chemoembolization (TACE) in different populations of hepatocellular carcinoma (HCC) patients is still unclear. This meta-analysis explores the impact of TACE on survival outcomes in elderly versus younger patients with HCC, considering regional variations and heterogeneity among studies.</p><p><strong>Methods: </strong>Nineteen studies involving 30,093 participants were systematically reviewed from January 1964 to January 2024. Data were pooled using random-effects models to calculate hazard ratios (HRs) and odds ratios (ORs) with 95% confidence intervals (CI) for overall survival and survival rates, respectively. Subgroup analyses were conducted based on age cut-offs and geographical regions to assess the effect of these variables on treatment outcomes.</p><p><strong>Results: </strong>Pooled HR for overall survival did not show a significant difference between elderly and younger patients (HR = 1.00; 95% CI: 0.98 to 1.02), with similar findings for survival rates (OR = 0.82; 95% CI: 0.46 to 1.45). Substantial heterogeneity was observed (I² = 78.0% for HR and 94.3% for OR), with notable regional differences indicating lower survival odds in European studies compared to Asian ones. No significant effect (OR = 0.95) was detected in prospective studies, while retrospective studies indicated a significant reduction in survival rates in elderly patients (OR = 0.35).</p><p><strong>Conclusion: </strong>TACE appears to be equally effective in elderly and younger HCC patients. However, significant regional differences and study heterogeneity suggest the need for personalized treatment approaches. Further research is required to understand the underlying causes of these variations and to optimize TACE protocols.</p>","PeriodicalId":19958,"journal":{"name":"Pakistan Journal of Medical Sciences","volume":"41 4","pages":"1234-1243"},"PeriodicalIF":1.2,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12022578/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144035263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Total hip arthroplasty: 30 days readmission at a tertiary care hospital. 全髋关节置换术:在三级医院再入院30天。
IF 1.2 4区 医学
Pakistan Journal of Medical Sciences Pub Date : 2025-04-01 DOI: 10.12669/pjms.41.4.11041
Muhammad Omer Farooq, Mahnoor Tariq, Ahsan Sulaiman, Shahryar Noordin
{"title":"Total hip arthroplasty: 30 days readmission at a tertiary care hospital.","authors":"Muhammad Omer Farooq, Mahnoor Tariq, Ahsan Sulaiman, Shahryar Noordin","doi":"10.12669/pjms.41.4.11041","DOIUrl":"https://doi.org/10.12669/pjms.41.4.11041","url":null,"abstract":"<p><strong>Objectives: </strong>To assess 30-day readmission at a tertiary care hospital following Total Hip Arthroplasty (THA) and to assess complications for which the patients were readmitted along with associated factors.</p><p><strong>Methods: </strong>This prospective observational study examined patients undergoing THA at The Aga Khan University Hospital from February 2023 to December 2023. Patients were followed after THA up to 30 days. They were followed using an electronic medical record number system. Data on patient demographics and procedure was collected, along with reason for re-admission within 30-days. Statistical analysis was done using STATA version 15.1, where in descriptive statistics median and interquartile range, and frequencies and percentages were determined followed by Fisher's exact test.</p><p><strong>Results: </strong>A total of 67 patients were included in the study. Four male patients above 55 years were readmitted within 30-days of THA. Underlying diagnosis was a significant factor for re-admission (p=0.05). Although, OA and AVN were commonly reported in patients >55 years, two of the readmitted patients had an underlying diagnosis of femoral neck fracture.</p><p><strong>Conclusion: </strong>Diagnosis at the time of admission for THA is a substantial risk factor for readmission that warrants further investigation. In addition, it underscores the need for targeted post-operative monitoring to reduce readmissions especially for patients who are at high risk of readmission.</p>","PeriodicalId":19958,"journal":{"name":"Pakistan Journal of Medical Sciences","volume":"41 4","pages":"947-951"},"PeriodicalIF":1.2,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12022582/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144037511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Paediatric Systemic Lupus Erythematosus with chronic diarrhea as an initial presentation. 以慢性腹泻为首发表现的小儿系统性红斑狼疮。
IF 1.2 4区 医学
Pakistan Journal of Medical Sciences Pub Date : 2025-04-01 DOI: 10.12669/pjms.41.4.10235
Ali Abdur Rahman, Asfand Tariq
{"title":"Paediatric Systemic Lupus Erythematosus with chronic diarrhea as an initial presentation.","authors":"Ali Abdur Rahman, Asfand Tariq","doi":"10.12669/pjms.41.4.10235","DOIUrl":"https://doi.org/10.12669/pjms.41.4.10235","url":null,"abstract":"<p><p>Lupus enteritis (LE) is a rare manifestation of Childhood Systemic lupus erythematosus (cSLE). The presentation is non-specific i.e loose motions, non-specific abdominal pain, nausea and vomiting. Presenting as a sole initial clinical finding in the absence of other common findings of systemic lupus erythematosus (SLE) makes the diagnosis challenging. After a detailed workup, our patient was diagnosed with LE based on history, physical and laboratory investigations and responded well with initial management. Our report emphasizes the rarity of LE and the significance of its prevalence in the childhood population due to increased morbidity, mortality and complications such as intestinal bleeding, perforation and infarction. With early diagnosis and treatment, there is an excellent prognosis.</p>","PeriodicalId":19958,"journal":{"name":"Pakistan Journal of Medical Sciences","volume":"41 4","pages":"1257-1260"},"PeriodicalIF":1.2,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12022599/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144031874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Development and validation of a Nomogram for the prediction of patients with sepsis-induced multiple organ dysfunction syndrome. 用于预测脓毒症诱导的多器官功能障碍综合征患者的Nomogram预测图的开发和验证。
IF 1.2 4区 医学
Pakistan Journal of Medical Sciences Pub Date : 2025-04-01 DOI: 10.12669/pjms.41.4.10421
Jinling Ji, Qiong Wang, Kai Wang, Ting Shi, Chang Li
{"title":"Development and validation of a Nomogram for the prediction of patients with sepsis-induced multiple organ dysfunction syndrome.","authors":"Jinling Ji, Qiong Wang, Kai Wang, Ting Shi, Chang Li","doi":"10.12669/pjms.41.4.10421","DOIUrl":"https://doi.org/10.12669/pjms.41.4.10421","url":null,"abstract":"<p><strong>Objective: </strong>To develop and validate a model capable of predicting the risk of Sepsis-induced multiple organ dysfunction syndrome (SI-MODS) in hospitalized sepsis patients.</p><p><strong>Methods: </strong>A retrospective cohort study was performed to analyze the clinical data of 415 patients admitted to Department of Medical Laboratory, The Affiliated Huai'an No.1 People's Hospital of Nanjing between January 2019 and January 2022. The least absolute shrinkage and selection operator (LASSO) regression analysis was employed to pinpoint potential variables. A nomogram was developed through multivariate logistic regression. For internal validation, the bootstrapping method was utilized. The nomogram's performance was assessed through calibration, discrimination, and clinical utility analyses.</p><p><strong>Results: </strong>Among the 415 patients, SI-MODS was identified in 46 individuals (11.1%). This model identified seven key variables. The model's internal validation yielded an area under the curve of 0.903 (95% CI: 0.863-0.943). The model's calibration was strong, and results from a decision curve analysis showed that the created nomogram provided a net benefit across a threshold probability range of 1-66% for predicting SI-MODS.</p><p><strong>Conclusion: </strong>Our study develops a nomogram incorporating based on PaO2, LAC, multidrug resistant bacteria, septic shock, coagulation disorder, mechanical ventilation, and kidney failure can predict the risk of MODS in sepsis patients, which helps clinicians make risk based decisions and treatment strategies.</p>","PeriodicalId":19958,"journal":{"name":"Pakistan Journal of Medical Sciences","volume":"41 4","pages":"1036-1046"},"PeriodicalIF":1.2,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12022554/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144014439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of integrated care model on urinary retention after radical hysterectomy for cervical cancer. 综合护理模式对宫颈癌根治性子宫切除术后尿潴留的影响。
IF 1.2 4区 医学
Pakistan Journal of Medical Sciences Pub Date : 2025-04-01 DOI: 10.12669/pjms.41.4.9917
Qiang Zhao
{"title":"Effect of integrated care model on urinary retention after radical hysterectomy for cervical cancer.","authors":"Qiang Zhao","doi":"10.12669/pjms.41.4.9917","DOIUrl":"https://doi.org/10.12669/pjms.41.4.9917","url":null,"abstract":"<p><strong>Objective: </strong>To explore the impact of integrated care model on urinary retention after extensive hysterectomy for cervical cancer.</p><p><strong>Methods: </strong>This was a retrospective study. Sixty eight patients with cervical cancer who underwent extensive hysterectomy in Tangshan People's Hospital from March 2021 to March 2023 were divided into experimental group and control group, 34 cases each. The experimental group received an integrated care model, including periurethral irrigation, pelvic floor muscle and abdominal muscle exercise, induction of urination, bladder function training, and psychological care; the control group adopted a routine care model.</p><p><strong>Results: </strong>The incidence of complications in the experimental group was lower than that in the control group, and the difference was statistically significant (χ<sup>2</sup>=4.221, P=0.040). After nursing, the SAS, SDS and SF-36 scores of the two groups of patients were significantly improved compared with those before nursing, and the degree of laboratory improvement was higher than that of the control group. The differences were statistically significant (P<0.05). The nursing satisfaction of the experimental group was higher than that of the control group, and the difference was statistically significant (χ<sup>2</sup>=4.660, P=0.031).</p><p><strong>Conclusion: </strong>Adopting an integrated care model for patients with cervical cancer after extensive hysterectomy can shorten the time of indwelling urinary catheter, reduce residual urine volume and urinary catheter reset rate, improve patients' bladder function, alleviate patients' negative emotions, and effectively improve patients' quality of life.</p>","PeriodicalId":19958,"journal":{"name":"Pakistan Journal of Medical Sciences","volume":"41 4","pages":"963-967"},"PeriodicalIF":1.2,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12022550/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144006119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Quadratus lumborum block vs femoral/fascia iliaca block for hip surgeries: A systematic review and meta-analysis. 髋部手术腰方肌阻滞vs股/髂筋膜阻滞:系统回顾和荟萃分析。
IF 1.2 4区 医学
Pakistan Journal of Medical Sciences Pub Date : 2025-04-01 DOI: 10.12669/pjms.41.4.11531
Yufan Wang, Lina Zhu
{"title":"Quadratus lumborum block vs femoral/fascia iliaca block for hip surgeries: A systematic review and meta-analysis.","authors":"Yufan Wang, Lina Zhu","doi":"10.12669/pjms.41.4.11531","DOIUrl":"https://doi.org/10.12669/pjms.41.4.11531","url":null,"abstract":"<p><strong>Objective: </strong>The current systematic review was conducted to compare quadratus lumborum block (QLB) vs fascia iliaca block (FIB) and femoral nerve block (FNB) for improving analgesic outcomes in patients undergoing hip surgeries.</p><p><strong>Methods: </strong>We searched for randomized controlled trials from inception to on Embase, PubMed, Web of Science, clinical trial registry, and Google Scholar comparing QLB vs FIB/FNB for hip surgeries. The search was initiated on 1<sup>st</sup> December and culminated on 5<sup>th</sup> December 2023 to include all studies published from inception till the last day of the search. The primary outcome was 24 hours total analgesic consumption in morphine equivalents. Secondary outcomes were pain scores and incidence of quadriceps weakness at 24 hours, and postoperative nausea and vomiting (PONV).</p><p><strong>Results: </strong>Six RCTs were eligible. The meta-analysis found that 24-hours morphine consumption was found to be significantly lower in the FIB/FNB group as compared to the QLB group. Pain scores on the 10-point scale were not significantly different between the two groups at one to two hours, two to four hours, 12 hours, 24 hours, and 48 hours. Incidence of quadriceps weakness and PONV was also not significantly difference between the two groups.</p><p><strong>Conclusion: </strong>Meta-analysis of a limited number of RCTs shows that QLB does not provide better postoperative analgesia as compared to FIB/FNB after hip surgery. Twenty four hours total opioid consumption was significantly higher with QLB but without any difference in pain scores. Incidence of quadriceps weakness and PONV does not differ between QLB and FIB/FNB.</p>","PeriodicalId":19958,"journal":{"name":"Pakistan Journal of Medical Sciences","volume":"41 4","pages":"1193-1201"},"PeriodicalIF":1.2,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12022575/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144042102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A cross-sectional study on the comparison of serum SIRT-1 and MMP-9 levels of patients with bronchiectasis and healthy controls. 支气管扩张患者与健康对照者血清SIRT-1和MMP-9水平比较的横断面研究
IF 1.2 4区 医学
Pakistan Journal of Medical Sciences Pub Date : 2025-04-01 DOI: 10.12669/pjms.41.4.10877
Deniz Bakir, Mustafa D Bedir, Dilara Ulger Ozbek, Zehra Seyfikli
{"title":"A cross-sectional study on the comparison of serum SIRT-1 and MMP-9 levels of patients with bronchiectasis and healthy controls.","authors":"Deniz Bakir, Mustafa D Bedir, Dilara Ulger Ozbek, Zehra Seyfikli","doi":"10.12669/pjms.41.4.10877","DOIUrl":"https://doi.org/10.12669/pjms.41.4.10877","url":null,"abstract":"<p><strong>Background & objectives: </strong>Bronchiectasis is the permanent enlargement of the bronchi following damage to the respiratory tract (bronchi) in the lungs. Bronchiectasis not associated with cystic fibrosis is gaining an increasing place among chronic respiratory diseases worldwide. The purpose of this study was to identify the levels of MMP-9, known to cause bronchial damage in chronic pulmonary illness, and SIRT-1, an anti-aging and anti-infective regulatory protein, in patients with bronchiectasis and to evaluate the importance of these biomarkers in diagnosis.</p><p><strong>Methods: </strong>This cross-sectional study was conducted in the Chest Diseases Clinic of Sivas Cumhuriyet University Medical Faculty Hospital between November 2020 and September 2022. We recruited 30 patients with bronchiectasis whose diagnosis was verified by high-resolution chest CT scan and 30 healthy controls. SIRT-1 and MMP-9 levels in the serum of the study group were determined by the ELISA method.</p><p><strong>Results: </strong>SIRT-1 and MMP-9 concentrations were found to be statistically significant. In comparison to the control group, it was observed that the bronchiectasis group had a lower serum SIRT-1 levels (p<0.001). The bronchiectasis group had higher serum MMP-9 values than the control group (p<0.001). Age-related differences in SIRT-1 and MMP-9 concentrations were not observed. No correlation was found between MMP-9 and SIRT-1. The results of Receiver Operating Characteristic (ROC) analysis indicated that MMP-9 has relatively high sensitivities.</p><p><strong>Conclusions: </strong>We concluded that, higher inflammation elevates MMP-9 levels while decreasing SIRT-1 levels. MMP-9 and SIRT-1 may be potential biomarkers in the diagnosis of bronchiectasis.</p>","PeriodicalId":19958,"journal":{"name":"Pakistan Journal of Medical Sciences","volume":"41 4","pages":"1052-1057"},"PeriodicalIF":1.2,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12022576/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143975840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effectiveness of animation as a learning tool in applied medical sciences education: A comparative cross-sectional study among university students. 动画作为一种学习工具在应用医学教育中的有效性:一项在大学生中的比较横断面研究。
IF 1.2 4区 医学
Pakistan Journal of Medical Sciences Pub Date : 2025-04-01 DOI: 10.12669/pjms.41.4.11204
Faisal Mousa Alzahrani
{"title":"Effectiveness of animation as a learning tool in applied medical sciences education: A comparative cross-sectional study among university students.","authors":"Faisal Mousa Alzahrani","doi":"10.12669/pjms.41.4.11204","DOIUrl":"https://doi.org/10.12669/pjms.41.4.11204","url":null,"abstract":"<p><strong>Background & objectives: </strong>This study investigates the effectiveness of animation compared to traditional lecture methods on student performance, cognitive outcomes, and knowledge retention among Applied Medical Sciences University students.</p><p><strong>Methods: </strong>In this cross-sectional comparative study, a total of 110 students from the College of Applied Medical Sciences (CAMS), Imam Abdulrahman bin Faisal University participated in the study conducted between 1<sup>st</sup> April to 30<sup>th</sup> June 2024. Participants were divided into two groups: one receiving traditional lecture-based instruction and the other receiving animated instructional content. Quizzes were structured into two components to evaluate knowledge retention and cognitive skills. The study further analyzed performance, gender differences, and academic year to assess the efficacy of animation.</p><p><strong>Results: </strong>The animation group outperformed the traditional group in overall scores of 72.48±10.13 vs. 61.16±12.30, (p=0.001), and the passing rate scaled were 60% and 80%. Largely significant differences were seen in male students (p=0.002) and fourth-year students (p=0.001) in the animation group. Knowledge and cognitive assessments showed statistically significant gains in the animation group compared to traditional methods (p< 0.05).</p><p><strong>Conclusion: </strong>Animation-based learning significantly enhances student performance, particularly in cognitive tasks, and is especially beneficial for fourth-year students. This highlights the effectiveness of animation as a teaching tool. Incorporating it can enhance learning outcomes and academic success in applied medical sciences education.</p>","PeriodicalId":19958,"journal":{"name":"Pakistan Journal of Medical Sciences","volume":"41 4","pages":"1116-1120"},"PeriodicalIF":1.2,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12022563/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143977292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of submaximal interval training on anthropometric measurements, endurance, and flexibility of lower back and hamstrings in healthy individuals with a sedentary lifestyle. 亚最大间歇训练对久坐生活方式的健康个体的人体测量、耐力和下背部和腘绳肌柔韧性的影响
IF 1.2 4区 医学
Pakistan Journal of Medical Sciences Pub Date : 2025-04-01 DOI: 10.12669/pjms.41.4.10163
Ikram Ali, Haider Darain, Muhammad Idrees Khan, Maria Ishaq Khattak, Aatik Arsh
{"title":"Effects of submaximal interval training on anthropometric measurements, endurance, and flexibility of lower back and hamstrings in healthy individuals with a sedentary lifestyle.","authors":"Ikram Ali, Haider Darain, Muhammad Idrees Khan, Maria Ishaq Khattak, Aatik Arsh","doi":"10.12669/pjms.41.4.10163","DOIUrl":"https://doi.org/10.12669/pjms.41.4.10163","url":null,"abstract":"<p><strong>Objective: </strong>To determine the effects of submaximal interval training on anthropometric measurements, endurance, and flexibility of lower back and hamstrings in people with sedentary lifestyle.</p><p><strong>Methods: </strong>A quasi-experimental design was employed in this study involving 20 sedentary participants (12 females and eight males mean age: 27.20±8.48. The study conducted at Physical Therapy gym Khyber Medical University Peshawar from January 2019 to June 2019. Over four weeks, participants underwent a submaximal interval training program, comprising treadmill walking or running at 70-80% of their maximum heart rate for one minute, followed by one minute of active recovery conducted three time weekly. Assessments comprised of endurance VO2 max using the Bruce Protocol, flexibility of the lower back extensors and hamstring muscles through the Young Man Christian Association (YMCA) sit and reach test, body mass index (BMI) and waist-hip ratio (WHR).</p><p><strong>Results: </strong>The submaximal interval training intervention yielded significant improvements in endurance VO2 max, (p=0.001), flexibility (p=0.001) and BMI (p=0.016). However, the waist-hip ratio did not show any significant changes, mean pre-score (0.83±0.95) remaining the same in the post-score (0.83±0.93) (p=0.64).</p><p><strong>Conclusion: </strong>The submaximal interval training intervention demonstrated a high level of tolerance, as evidenced by a remarkable adherence rate of 91% among participants. Moreover, this training approach exhibited significant enhancements in various physical parameters.</p>","PeriodicalId":19958,"journal":{"name":"Pakistan Journal of Medical Sciences","volume":"41 4","pages":"1132-1137"},"PeriodicalIF":1.2,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12022569/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143993175","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Obstetrical outcome in pregnant women presenting with congenital uterine anomalies. 以先天性子宫畸形为表现的孕妇的产科结局。
IF 1.2 4区 医学
Pakistan Journal of Medical Sciences Pub Date : 2025-04-01 DOI: 10.12669/pjms.41.4.10793
Shahida Sutan, Samina Alia Sabir, Nazia Liaqat, Qudsia Qazi
{"title":"Obstetrical outcome in pregnant women presenting with congenital uterine anomalies.","authors":"Shahida Sutan, Samina Alia Sabir, Nazia Liaqat, Qudsia Qazi","doi":"10.12669/pjms.41.4.10793","DOIUrl":"https://doi.org/10.12669/pjms.41.4.10793","url":null,"abstract":"<p><strong>Objective: </strong>To analyze the obstetrical outcome in pregnant women who presented with congenital uterine anomalies.</p><p><strong>Methods: </strong>Sixty patients participated in this descriptive study conducted at department of obstetrics and gynecology, Lady Reading Hospital, Peshawar from February 2023 to April 2024. Pregnant patients with CUA aged 20 to 35 years and gestational age 30 to 42 with singleton pregnancy were included. Classification of CUA was assessed along with negative obstetric outcomes. Data analysis was done using SPSS 20.</p><p><strong>Results: </strong>Septate uterus was detected in 13 (21.7%), unicornuate 5 (8.3%), bicornuate 32 (53.3%), and didelphys 10 (16.7%). Cesarean section 40 (66.7%), preterm delivery 21 (35%), malpresentation 33 (55%), SGA 36 (43.3%), and low birth weight 18 (30%) were negative obstetric outcomes. Unicornuate uterus and bicornuate uterus had greater caesarean section rates. Patients with unicornuate uterus, didelphys and septate had more preterm deliveries. Fetus malpresentation was higher in bicornuate uterus than other CUAs. Septate uterine patients had higher SGA and low birth weight rates.</p><p><strong>Conclusion: </strong>Our investigation confirms unfavorable obstetric outcomes are commonly linked to congenital uterine abnormalities.</p>","PeriodicalId":19958,"journal":{"name":"Pakistan Journal of Medical Sciences","volume":"41 4","pages":"1078-1081"},"PeriodicalIF":1.2,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12022557/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143993928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信