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Establishment of the indicator system for clinical rationality evaluation of antitumor drugs by the Delphi method 德尔菲法建立抗肿瘤药物临床合理性评价指标体系
Pharmaceutical Care and Research Pub Date : 2020-12-31 DOI: 10.5428/PCAR20200601
Yan Li, Weiyi Feng, W. Mao, Jian-hui Yan, Lin Wu, Xiaomin Si
{"title":"Establishment of the indicator system for clinical rationality evaluation of antitumor drugs by the Delphi method","authors":"Yan Li, Weiyi Feng, W. Mao, Jian-hui Yan, Lin Wu, Xiaomin Si","doi":"10.5428/PCAR20200601","DOIUrl":"https://doi.org/10.5428/PCAR20200601","url":null,"abstract":"","PeriodicalId":19943,"journal":{"name":"Pharmaceutical Care and Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44972992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Practice of online consultation of pharmacists during epidemic prevention of Corona Virus Disease-2019 and prospect of refined pharmaceutical care 2019冠状病毒病防疫药师在线咨询实践与精细化药学服务展望
Pharmaceutical Care and Research Pub Date : 2020-12-31 DOI: 10.5428/PCAR20200616
Yeyan Hu, Yan Pan, Mengwan Zhang, Jian-Guang Yu
{"title":"Practice of online consultation of pharmacists during epidemic prevention of Corona Virus Disease-2019 and prospect of refined pharmaceutical care","authors":"Yeyan Hu, Yan Pan, Mengwan Zhang, Jian-Guang Yu","doi":"10.5428/PCAR20200616","DOIUrl":"https://doi.org/10.5428/PCAR20200616","url":null,"abstract":"","PeriodicalId":19943,"journal":{"name":"Pharmaceutical Care and Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71177210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Investigation on pharmacy administration in primary medical institutions and improvement of pharmacists’ skills 基层医疗机构药学管理现状调查与药师队伍建设
Pharmaceutical Care and Research Pub Date : 2020-12-31 DOI: 10.5428/PCAR20200620
Dayong Zhou, Shang-xing Guo, Aina Liu, Li Zhou, Shan Jiang
{"title":"Investigation on pharmacy administration in primary medical institutions and improvement of pharmacists’ skills","authors":"Dayong Zhou, Shang-xing Guo, Aina Liu, Li Zhou, Shan Jiang","doi":"10.5428/PCAR20200620","DOIUrl":"https://doi.org/10.5428/PCAR20200620","url":null,"abstract":"","PeriodicalId":19943,"journal":{"name":"Pharmaceutical Care and Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47274776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Analysis of typical cases of irrational use of immunosuppressants 不合理使用免疫抑制剂的典型案例分析
Pharmaceutical Care and Research Pub Date : 2020-12-31 DOI: 10.5428/PCAR20200611
Quan-jing Chen, Qinyong Shen, Zhengbiao Ni, Hongtao Song
{"title":"Analysis of typical cases of irrational use of immunosuppressants","authors":"Quan-jing Chen, Qinyong Shen, Zhengbiao Ni, Hongtao Song","doi":"10.5428/PCAR20200611","DOIUrl":"https://doi.org/10.5428/PCAR20200611","url":null,"abstract":"","PeriodicalId":19943,"journal":{"name":"Pharmaceutical Care and Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49469895","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Determination of linezolid concentration in the plasma of the patients from the Department of Hematology by UPLC method UPLC法测定血液科患者血浆中利奈唑胺浓度
Pharmaceutical Care and Research Pub Date : 2020-12-31 DOI: 10.5428/PCAR20200603
C. Ming, Yuefan Shen, Guorong Fan, Yuanjun Tang
{"title":"Determination of linezolid concentration in the plasma of the patients from the Department of Hematology by UPLC method","authors":"C. Ming, Yuefan Shen, Guorong Fan, Yuanjun Tang","doi":"10.5428/PCAR20200603","DOIUrl":"https://doi.org/10.5428/PCAR20200603","url":null,"abstract":"","PeriodicalId":19943,"journal":{"name":"Pharmaceutical Care and Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49402905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pharmaceutical practice and experience of clinical pharmacists engaged in the treatment of cancer pain 癌症疼痛临床药师的药学实践与体会
Pharmaceutical Care and Research Pub Date : 2020-12-31 DOI: 10.5428/PCAR20200612
Quan Hui, Junmei Song, Xin Liu, Yang Yang, Chun-ling Tang
{"title":"Pharmaceutical practice and experience of clinical pharmacists engaged in the treatment of cancer pain","authors":"Quan Hui, Junmei Song, Xin Liu, Yang Yang, Chun-ling Tang","doi":"10.5428/PCAR20200612","DOIUrl":"https://doi.org/10.5428/PCAR20200612","url":null,"abstract":"","PeriodicalId":19943,"journal":{"name":"Pharmaceutical Care and Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49191119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Exploration of the teaching mode of therapeutic drug monitoring in hospital pharmacy for pharmaceutical undergraduates under the guidance of micro film 微电影指导下药学本科生医院药学治疗药物监测教学模式的探索
Pharmaceutical Care and Research Pub Date : 2020-12-31 DOI: 10.5428/PCAR20200605
Xuebin Wang, Jing Tian, Nan Ding, Jiao Qian, Yunyun Yang, Zhuo Wang
{"title":"Exploration of the teaching mode of therapeutic drug monitoring in hospital pharmacy for pharmaceutical undergraduates under the guidance of micro film","authors":"Xuebin Wang, Jing Tian, Nan Ding, Jiao Qian, Yunyun Yang, Zhuo Wang","doi":"10.5428/PCAR20200605","DOIUrl":"https://doi.org/10.5428/PCAR20200605","url":null,"abstract":"","PeriodicalId":19943,"journal":{"name":"Pharmaceutical Care and Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43855442","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Construction of a platform for the transformation from general pharmacists to information pharmacists using the quality control circle 利用质量控制圈构建从普通药剂师向信息药剂师转变的平台
Pharmaceutical Care and Research Pub Date : 2020-10-31 DOI: 10.5428/PCAR20200511
H. Peng, Ru Shi, Hongju Lin, Xinrong Wu, Bai Qin
{"title":"Construction of a platform for the transformation from general pharmacists to information pharmacists using the quality control circle","authors":"H. Peng, Ru Shi, Hongju Lin, Xinrong Wu, Bai Qin","doi":"10.5428/PCAR20200511","DOIUrl":"https://doi.org/10.5428/PCAR20200511","url":null,"abstract":"Objective： To explore and construct a platform for the transformation from general pharmacists to information pharmacists using quality control circle（QCC） activities.Methods： The QCC activities were applied to the whole training process of information pharmacists.Training started through the approach of having the pharmacists learn programming sentences，and program writing was finally completed after continuous exploration.Results： Through QCC activities，3 information pharmacists were initially trained，the writing of 2 programs were completed and a set of standard training profiles was summarized.Conclusion： The QCC activities could be used for pharmacy management and personnel training.It is particularly the case when more difficult targets are set for the work.Compared with the general team，the team implementing the QCC is more resolute and clearer in work goals and more liable to complete the project.","PeriodicalId":19943,"journal":{"name":"Pharmaceutical Care and Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43618667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pharmaceutical care of a patient with severe hand-foot skin reactions induced by apatinib mesylate and literature review 甲磺酸阿帕替尼引起严重手足皮肤反应的药物治疗及文献复习
Pharmaceutical Care and Research Pub Date : 2020-10-31 DOI: 10.5428/PCAR20200514
Doudou He, Xiaochun Zheng
{"title":"Pharmaceutical care of a patient with severe hand-foot skin reactions induced by apatinib mesylate and literature review","authors":"Doudou He, Xiaochun Zheng","doi":"10.5428/PCAR20200514","DOIUrl":"https://doi.org/10.5428/PCAR20200514","url":null,"abstract":"Objective： To explore pharmaceutical care methods for hand-foot skin reactions induced by apatinib mesylate tablets，so as to provide reference for rational use of drugs clinically.Methods： A case of severe hand-foot skin reactions induced by apatinib mesylate tablets in the treatment of advanced gastric cancer was reported.The clinical manifestations，treatment principles and possible mechanism of the disease were reviewed in combination with literature.Results： Most of the hand-foot skin reactions caused by oral administration of apatinib mesylate tablets occurred 2-3 weeks after medication，mostly with clinical manifestations of erythema in palms，fingers，joints and toes accompanied with swelling and pain，as well as hyperkeratosis of the skin with paresthesia.The occurrence of hand-foot skin reactions caused by apatinib mesylate tablets were associated with such factors as inhibition of vascular endothelial growth factor and decreased capillary repair capacity and other factors.To prevent its occurrence，daily life care，adjustment of the dosage of apatinib mesylate，external application of topical emollients containing urea，analgesics and external use of super-potent topical corticosteroids could obviously reduce the severity of hand-foot skin reactions.If hand-foot skin reactions were recurrent and difficult to control，replacement with other targeted drugs could be considered.Conclusion： In the application of apatinib mesylate tablets，hand-foot skin reactions were not rare.Close attention should be paid to drug monitoring on the part of clinicians and clinical pharmacists，so that the occurrence of adverse drug reactions could be reduced.In case there were hand-foot skin reactions，timely symptomatic treatment and close observation should be given，so as to improve the safety and efficacy of drug therapy.","PeriodicalId":19943,"journal":{"name":"Pharmaceutical Care and Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43970965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Feasibility study of morphine-induced rat pica model by tail vein injection to replace vomiting model 尾静脉注射吗啡诱导大鼠异食癖模型替代呕吐模型的可行性研究
Pharmaceutical Care and Research Pub Date : 2020-10-31 DOI: 10.5428/PCAR20200510
W. Zhou, P. Bao, Wenjun Guo, T. Hong, Menwang Yang, Shangping Fang
{"title":"Feasibility study of morphine-induced rat pica model by tail vein injection to replace vomiting model","authors":"W. Zhou, P. Bao, Wenjun Guo, T. Hong, Menwang Yang, Shangping Fang","doi":"10.5428/PCAR20200510","DOIUrl":"https://doi.org/10.5428/PCAR20200510","url":null,"abstract":"Objective： To explore the feasibility of the morphine-induced rat pica model by tail vein injection to replace the vomiting model，and the effective dose of morphine with less severe complications when the model was developed.Methods： Fifty SD rats were randomly divided into the blank control group and the M1，M2，M3 and M4 groups，each consisting of 10 animals. The rats in the blank control group were injected with 10 ml/kg normal saline（NS） via tail vein，while the animals in the M1，M2，M3 and M4 groups were injected with morphine hydrochloride injection at a dosage of 5，10，20 and 30 mg/kg via tail vein.Heart rate，blood oxygen saturation and activities of the animals were closely observed and recorded at 5，10 and 15 minutes after medication.Then，changes in the intake of kaolin，feed and water of the rats in each group were recorded and compared between the groups for 4 successive days after medication.Results： The blood oxygen saturation in the morphine treatment groups all reduced significantly，and statistical significance could be seen，when it was compared with that of the blank control group（P<0.05）.On the first day after medication，the intake of kaolin in the M3 and M4 groups increased significantly，as compared with that of the blank control group（P<0.05）.On the third day after medication，the intake of kaolin in the M1 group significantly increased，as compared with that of the blank control group（P<0.05）.Conclusion： The rat pica model was established by tail vein injection of morphine，which could be used to replace the vomiting model.The effective dose of morphine was 20 mg/kg with less severe complications.","PeriodicalId":19943,"journal":{"name":"Pharmaceutical Care and Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49396990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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