{"title":"RETRACTION: The Dual Roles of Melatonin Biosynthesis Enzymes in the Coordination of Melatonin Biosynthesis and Autophagy in Cassava","authors":"","doi":"10.1111/jpi.70172","DOIUrl":"https://doi.org/10.1111/jpi.70172","url":null,"abstract":"<p><b>RETRACTION</b>: Y. Wei, Y. Bai, X. Cheng, B. Zhu, R. J. Reiter, and H. Shi, “The Dual Roles of Melatonin Biosynthesis Enzymes in the Coordination of Melatonin Biosynthesis and Autophagy in Cassava,” <i>Journal of Pineal Research</i> 69, no. 1 (2020): e12652, https://doi.org/10.1111/jpi.12652.</p><p>The above article, published online on 23 March 2020 in Wiley Online Library (wileyonlinelibrary.com), has been retracted by agreement between the journal Editor-in-Chief, Gianluca Tosini; and John Wiley & Sons Ltd. A report on PubPeer [1] indicated that the pTRV and pTRV-MeASMT3 images in Figure 3D had been duplicated and presented as different samples in Figure 7B following rotation and further alteration. Additionally, several samples presented in Figure 4 contained overlapping or duplicated images. These concerns were confirmed by the publisher.</p><p>The authors responded to an inquiry by the publisher and reported that an additional image duplication had occurred in between Figures 6C and 7C, in addition to the other errors. They reported that the duplications were due to mistakes during manuscript preparation. While the authors presented original as well as repeat data with the intention of correcting these errors, the authors did not provide a satisfactory explanation for the evidence of image rotation and alteration of images between Figures 3 and 7. Therefore, the publisher and the editor have lost confidence in the results and the conclusions, and the article must be retracted. The authors agree with the retraction.</p>","PeriodicalId":198,"journal":{"name":"Journal of Pineal Research","volume":"78 4","pages":""},"PeriodicalIF":7.5,"publicationDate":"2026-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jpi.70172","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148467173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"RETRACTION: The Dual Roles of Melatonin Biosynthesis Enzymes in the Coordination of Melatonin Biosynthesis and Autophagy in Cassava","authors":"","doi":"10.1111/jpi.70172","DOIUrl":"https://doi.org/10.1111/jpi.70172","url":null,"abstract":"<p><b>RETRACTION</b>: Y. Wei, Y. Bai, X. Cheng, B. Zhu, R. J. Reiter, and H. Shi, “The Dual Roles of Melatonin Biosynthesis Enzymes in the Coordination of Melatonin Biosynthesis and Autophagy in Cassava,” <i>Journal of Pineal Research</i> 69, no. 1 (2020): e12652, https://doi.org/10.1111/jpi.12652.</p><p>The above article, published online on 23 March 2020 in Wiley Online Library (wileyonlinelibrary.com), has been retracted by agreement between the journal Editor-in-Chief, Gianluca Tosini; and John Wiley & Sons Ltd. A report on PubPeer [1] indicated that the pTRV and pTRV-MeASMT3 images in Figure 3D had been duplicated and presented as different samples in Figure 7B following rotation and further alteration. Additionally, several samples presented in Figure 4 contained overlapping or duplicated images. These concerns were confirmed by the publisher.</p><p>The authors responded to an inquiry by the publisher and reported that an additional image duplication had occurred in between Figures 6C and 7C, in addition to the other errors. They reported that the duplications were due to mistakes during manuscript preparation. While the authors presented original as well as repeat data with the intention of correcting these errors, the authors did not provide a satisfactory explanation for the evidence of image rotation and alteration of images between Figures 3 and 7. Therefore, the publisher and the editor have lost confidence in the results and the conclusions, and the article must be retracted. The authors agree with the retraction.</p>","PeriodicalId":198,"journal":{"name":"Journal of Pineal Research","volume":"78 4","pages":""},"PeriodicalIF":7.5,"publicationDate":"2026-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jpi.70172","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148467232","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"EXPRESSION OF CONCERN: Melatonin Protects Against Diabetic Cardiomyopathy Through Mst1/Sirt3 Signaling","authors":"","doi":"10.1111/jpi.70173","DOIUrl":"https://doi.org/10.1111/jpi.70173","url":null,"abstract":"<p><b>EXPRESSION OF CONCERN</b>: M. Zhang, J. Lin, S. Wang, Z. Cheng, J. Hu, T. Wang, W. Man, T. Yin, W. Guo, E. Gao, R. J. Reiter, H. Wang, and D. Sun, “Melatonin Protects Against Diabetic Cardiomyopathy Through Mst1/Sirt3 Signaling,” <i>Journal of Pineal Research</i> 63, no. 2 (2017): e12418, https://doi.org/10.1111/jpi.12418.</p><p>This Expression of Concern is for the above article, published online on 08 May 2017 in Wiley Online Library (wileyonlinelibrary.com), and has been issued by agreement between the journal Editor-in-Chief, Gianluca Tosini; and John Wiley & Sons Ltd. A report on PubPeer [<span>1</span>] indicated that the Control images in Figure 1E overlapped with the Control images in Figure 6E, though both represent distinct experimental conditions. Additionally, the report indicated that the Mst1<sup>-/-</sup>+Mel image in Figure 4E overlapped with the Tg-Mst1+Mel image in Figure 5E. Additional investigation by the publisher found evidence of potential splicing in some Western blot data.</p><p>The authors responded to an inquiry by the publisher and presented original data. However, not all of this data could be verified. This Expression of Concern has been published in order to inform and alert readers about the concerns of image overlap in Figures 1, 4, and 5. The authors were informed of this Expression of Concern.</p>","PeriodicalId":198,"journal":{"name":"Journal of Pineal Research","volume":"78 4","pages":""},"PeriodicalIF":7.5,"publicationDate":"2026-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jpi.70173","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148467233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"EXPRESSION OF CONCERN: Melatonin Protects Against Diabetic Cardiomyopathy Through Mst1/Sirt3 Signaling","authors":"","doi":"10.1111/jpi.70173","DOIUrl":"https://doi.org/10.1111/jpi.70173","url":null,"abstract":"<p><b>EXPRESSION OF CONCERN</b>: M. Zhang, J. Lin, S. Wang, Z. Cheng, J. Hu, T. Wang, W. Man, T. Yin, W. Guo, E. Gao, R. J. Reiter, H. Wang, and D. Sun, “Melatonin Protects Against Diabetic Cardiomyopathy Through Mst1/Sirt3 Signaling,” <i>Journal of Pineal Research</i> 63, no. 2 (2017): e12418, https://doi.org/10.1111/jpi.12418.</p><p>This Expression of Concern is for the above article, published online on 08 May 2017 in Wiley Online Library (wileyonlinelibrary.com), and has been issued by agreement between the journal Editor-in-Chief, Gianluca Tosini; and John Wiley & Sons Ltd. A report on PubPeer [<span>1</span>] indicated that the Control images in Figure 1E overlapped with the Control images in Figure 6E, though both represent distinct experimental conditions. Additionally, the report indicated that the Mst1<sup>-/-</sup>+Mel image in Figure 4E overlapped with the Tg-Mst1+Mel image in Figure 5E. Additional investigation by the publisher found evidence of potential splicing in some Western blot data.</p><p>The authors responded to an inquiry by the publisher and presented original data. However, not all of this data could be verified. This Expression of Concern has been published in order to inform and alert readers about the concerns of image overlap in Figures 1, 4, and 5. The authors were informed of this Expression of Concern.</p>","PeriodicalId":198,"journal":{"name":"Journal of Pineal Research","volume":"78 4","pages":""},"PeriodicalIF":7.5,"publicationDate":"2026-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jpi.70173","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148467174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Correction to “HsfA1a Upregulates Melatonin Biosynthesis to Confer Cadmium Tolerance in Tomato Plants”","authors":"","doi":"10.1111/jpi.70166","DOIUrl":"10.1111/jpi.70166","url":null,"abstract":"<p>Cai S, Zhang Y, Xu Y, et al. HsfA1a upregulates melatonin biosynthesis to confer cadmium tolerance in tomato plants. <i>J Pineal Res</i>, 2017, 62, e12387. DOI: 10.1111/jpi.12387.</p><p>After publication of the article, the authors identified an inaccuracy in a leaf phenotype image in Figure 1A: the leaf of <i>TRV-HsfA1a</i> under cadmium (Cd) stress (second row, second panel from the left). The authors sincerely apologize for any inconvenience caused by this oversight. The accurate image, obtained during the original experimental procedures, is provided below.</p><p>This correction does not alter the scientific integrity or conclusions of the study.</p><p>We apologize for this error.</p>","PeriodicalId":198,"journal":{"name":"Journal of Pineal Research","volume":"78 4","pages":""},"PeriodicalIF":7.5,"publicationDate":"2026-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13352095/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148417116","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Correction to “Melatonin Mediates Elevated Carbon Dioxide-Induced Photosynthesis and Thermotolerance in Tomato”","authors":"","doi":"10.1111/jpi.70165","DOIUrl":"10.1111/jpi.70165","url":null,"abstract":"<p>Hasan MK, Xing Q, Zhou C, et al. Melatonin mediates elevated carbon dioxide-induced photosynthesis and thermotolerance in tomato. <i>J Pineal Res</i>, 2023, e12858. DOI: 10.1111/jpi.12858.</p><p>After publication of the article, the authors identified an inconsistency in the background color of the pseudocolor Fv/Fm images in Figure 4A, as well as an inaccuracy in the NBT-staining image in Figure 4E, specifically, the comt1 mutant under ambient CO<sub>2</sub> (aCO<sub>2</sub>) and room temperature (Control) conditions (third row, third panel from the left). These errors have now been corrected.</p><p>This correction does not affect the scientific integrity or conclusions of the study. The accurate images, obtained during the original experimental procedures, are provided below.</p><p>We apologize for this error.</p>","PeriodicalId":198,"journal":{"name":"Journal of Pineal Research","volume":"78 4","pages":""},"PeriodicalIF":7.5,"publicationDate":"2026-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jpi.70165","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148417163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Correction to “Melatonin Attenuated Early Brain Injury Induced by Subarachnoid Hemorrhage via Regulating NLRP3 Inflammasome and Apoptosis Signaling”","authors":"","doi":"10.1111/jpi.70169","DOIUrl":"10.1111/jpi.70169","url":null,"abstract":"<p>Yushu Dong, Chongxi Fan, Wei Hu, Shuai Jiang, Zhiqiang Ma, Xiaolong Yan, Chao Deng, Shouyin Di, Zhenlong Xin, Guiling Wu, Yang Yang, Russel J Reiter, Guobiao Liang. Melatonin attenuated early brain injury induced by subarachnoid hemorrhage via regulating NLRP3 inflammasome and apoptosis signaling. J Pineal Res. 2016 Apr;60(3):253-62. doi:10.1111/jpi.12300. Epub 2016 Feb 15.</p><p>Readers found that the images of the Sham + vehicle group and Sham group in Figure 4B are duplicated. We have submitted all original data to the editorial office. Upon review and approval, Figure 4B is revised as shown below.</p><p>We apologize for this error.</p>","PeriodicalId":198,"journal":{"name":"Journal of Pineal Research","volume":"78 4","pages":""},"PeriodicalIF":7.5,"publicationDate":"2026-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jpi.70169","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148409745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Correction to “Melatonin Delays Leaf Senescence of Chinese Flowering Cabbage by Suppressing ABFs-Mediated Abscisic Acid Biosynthesis and Chlorophyll Degradation”","authors":"","doi":"10.1111/jpi.70167","DOIUrl":"10.1111/jpi.70167","url":null,"abstract":"<p>X. L. Tan, Z. Q. Fan, J. F. Kuang, et al., “Melatonin Delays Leaf Senescence of Chinese Flowering Cabbage by Suppressing ABFs-Mediated Abscisic Acid Biosynthesis and Chlorophyll Degradation,” <i>Journal of Pineal Research</i> 67, no. 1 (2019): e12570, https://doi.org/10.1111/jpi.12570.</p><p>Following publication, a concerned reader brought to our attention on an image duplication issue in Figure 1B. Specifically, the image for the Melatonin-0d sample was inadvertently taken from the Control-0d sample instead of the correct Melatonin-0d image. This error occurred during the image composite process due to our oversight.</p><p>The incorrect Melatonin-0d image has been replaced with the correct original machine-saved image from the Melatonin-0d time point. The corrected Figure 1B now accurately represents the Melatonin-0d sample. All other data and conclusions remain unchanged.</p><p>We apologize for this error.</p>","PeriodicalId":198,"journal":{"name":"Journal of Pineal Research","volume":"78 4","pages":""},"PeriodicalIF":7.5,"publicationDate":"2026-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jpi.70167","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148395326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Correction to “Melatonin Prevents Cell Death and Mitochondrial Dysfunction via a SIRT1-Dependent Mechanism During Ischemic-Stroke in Mice”","authors":"","doi":"10.1111/jpi.70168","DOIUrl":"10.1111/jpi.70168","url":null,"abstract":"<p>Yang Yang, Shuai Jiang, Yushu Dong, Chongxi Fan, Lei Zhao, Xiangmin Yang, Juan Li, Shouyin Di, Liang Yue, Guobiao Liang, Russel J Reiter, Yan Qu. Melatonin Prevents Cell Death and Mitochondrial Dysfunction via a SIRT1-Dependent Mechanism During Ischemic-Stroke in Mice. J Pineal Res. 2015 Jan;58(1):61–70. doi: 10.1111/jpi.12193. Epub 2014 Dec 9.</p><p>Some readers noticed duplicated images between the Melatonin + EX527 + IR group in Figure 3A and the Melatonin+IR group in Figure 1A. We have submitted all original data to the editorial office. With their review and approval, Figure 3A is revised. The correct Figure 3 is provided below.</p><p>We apologize for this error.</p>","PeriodicalId":198,"journal":{"name":"Journal of Pineal Research","volume":"78 4","pages":""},"PeriodicalIF":7.5,"publicationDate":"2026-07-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jpi.70168","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148389543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Correction to “Melatonin Antagonizes Cadmium-Induced Neurotoxicity By Activating the Transcription Factor Eb-Dependent Autophagy–Lysosome Machinery in Mouse Neuroblastoma Cells”","authors":"","doi":"10.1111/jpi.70163","DOIUrl":"https://doi.org/10.1111/jpi.70163","url":null,"abstract":"<p>Li M, Pi H, Yang Z, et al. Melatonin antagonizes cadmium-induced neurotoxicity by activating the transcription factor EB-dependent autophagy-lysosome machinery in mouse neuroblastoma cells. <i>J Pineal Res</i>. 2016;61(3):353–369.</p><p>After publication, concerns regarding image duplication in Figure 8B were brought to the authors' attention by a concerned reader. Specifically, in the originally published article, the LAMP1 immunoblot panel in Figure 8B was presented incorrectly due to an unintended duplication mistake with the PPARGC1A panel in Figure 10 A. Using the original source data, the rectified version of the incorrectly presented panel of Figure 8B has been generated and is shown below. This correction does not affect the description, interpretation, or conclusions of the original article.</p><p>We apologize for this error.</p>","PeriodicalId":198,"journal":{"name":"Journal of Pineal Research","volume":"78 4","pages":""},"PeriodicalIF":7.5,"publicationDate":"2026-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jpi.70163","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148386410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}