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Pathologia et microbiologia最新文献

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Skeletal effects of cholesterol feeding. 摄入胆固醇对骨骼的影响。
Pathologia et microbiologia Pub Date : 1975-01-01 DOI: 10.1159/000162839
R Silberberg
{"title":"Skeletal effects of cholesterol feeding.","authors":"R Silberberg","doi":"10.1159/000162839","DOIUrl":"https://doi.org/10.1159/000162839","url":null,"abstract":"<p><p>The effect of a 4% supplement of cholesterol to a standard diet on knee joints and vertebral columns was investigated in male mice of strain C57B1. The experimental diet was fed from the time of weaning through the 18-month period of observation or from the age of 1 year to the end of the experiment at 18 months of age. The incidence of osteoarthrosis was increased in mice fed cholesterol from the age of 12 months on. The incidence of spondylosis was increased after lifelong feeding as well as after feeding of cholesterol during the second year of life. This increase involved both, spondylosis associated with or uncomplicated by prolapse of intervertebral discs. The incidence of simple disc prolapse was not affected by the experimental diet.</p>","PeriodicalId":19854,"journal":{"name":"Pathologia et microbiologia","volume":"43 4","pages":"265-75"},"PeriodicalIF":0.0,"publicationDate":"1975-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000162839","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12405467","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Endocarditis parietalis eosinophilica-are there idiopathic forms? 壁性心内膜炎嗜酸性粒细胞增多——有特发性形式吗?
Pathologia et microbiologia Pub Date : 1975-01-01 DOI: 10.1159/000162802
T Hardmeier, H P Biedermann, H L Winklehner
{"title":"Endocarditis parietalis eosinophilica-are there idiopathic forms?","authors":"T Hardmeier,&nbsp;H P Biedermann,&nbsp;H L Winklehner","doi":"10.1159/000162802","DOIUrl":"https://doi.org/10.1159/000162802","url":null,"abstract":"","PeriodicalId":19854,"journal":{"name":"Pathologia et microbiologia","volume":"43 2-O","pages":"107-13"},"PeriodicalIF":0.0,"publicationDate":"1975-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000162802","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12405582","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Medionecrosis aortae. 主动脉中微血管病。
Pathologia et microbiologia Pub Date : 1975-01-01 DOI: 10.1159/000162806
A E Becker
{"title":"Medionecrosis aortae.","authors":"A E Becker","doi":"10.1159/000162806","DOIUrl":"https://doi.org/10.1159/000162806","url":null,"abstract":"","PeriodicalId":19854,"journal":{"name":"Pathologia et microbiologia","volume":"43 2-O","pages":"124-8"},"PeriodicalIF":0.0,"publicationDate":"1975-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000162806","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12405586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Natural history of primary lymphedema of the legs. 腿部原发性淋巴水肿的自然病史。
Pathologia et microbiologia Pub Date : 1975-01-01 DOI: 10.1159/000162826
U Brunner
{"title":"Natural history of primary lymphedema of the legs.","authors":"U Brunner","doi":"10.1159/000162826","DOIUrl":"https://doi.org/10.1159/000162826","url":null,"abstract":"","PeriodicalId":19854,"journal":{"name":"Pathologia et microbiologia","volume":"43 2-O","pages":"230-234"},"PeriodicalIF":0.0,"publicationDate":"1975-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000162826","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12417468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 14
F antigen. III. Immunological and biological properties. F抗原。3免疫学和生物学特性。
Pathologia et microbiologia Pub Date : 1975-01-01 DOI: 10.1159/000162727
R. Utzinger
{"title":"F antigen. III. Immunological and biological properties.","authors":"R. Utzinger","doi":"10.1159/000162727","DOIUrl":"https://doi.org/10.1159/000162727","url":null,"abstract":"Relationship of the isoforms of F antigens from A2G and CBA inbred mouse strains have been worked out in detail in respect to their immunogenicity. Mice from several inbred strains have been shown to possess the ability of forming anti-F upon stimulation with xenogeneic F antigens from certain species. An immunoelectrophoretic method for sensitive quantitation of the antigen is described. During human ontogenesis the antigen appears very early. It could never be detected in serum except in cases of acute liver disease. A small fragment set free under denaturing conditions showed the ability of inhibiting precipitation of the complete antigen by antibody. The F protein seems to be a vehicle for this small fragment possessing haptenic properties and probably being responsible for the universal cross-reactivity.","PeriodicalId":19854,"journal":{"name":"Pathologia et microbiologia","volume":"27 1","pages":"92-102"},"PeriodicalIF":0.0,"publicationDate":"1975-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88748477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
F antigen. II. Chemical and physical properties. F抗原。2化学和物理性质。
Pathologia et microbiologia Pub Date : 1975-01-01 DOI: 10.1159/000162716
R. Utzinger
{"title":"F antigen. II. Chemical and physical properties.","authors":"R. Utzinger","doi":"10.1159/000162716","DOIUrl":"https://doi.org/10.1159/000162716","url":null,"abstract":"Physical and chemical properties of the liver-specific F antigen suggested a model for the labile quarternary structure of the protein. The native molecule showed a size slightly larger than 60,000 dalton (d), which was reduced to about 40,000 d under acidic conditions. Breaking of hydrogen bonds by chaotropic treatment resulted in the release of components of 30,000, 7,000 and 2,000 d. The smallest component was split to fragments of about 1,000 d by the reducing action of sulfhydryl compounds.","PeriodicalId":19854,"journal":{"name":"Pathologia et microbiologia","volume":"12 1","pages":"3-14"},"PeriodicalIF":0.0,"publicationDate":"1975-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90631425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Inhibition of HBsAg immunologic reactivity and intestinal aerobic flora. 抑制HBsAg免疫反应性和肠道需氧菌群。
Pathologia et microbiologia Pub Date : 1975-01-01 DOI: 10.1159/000162731
V Molinari, L Cacciatore, G Cozzolino, M Piazza
{"title":"Inhibition of HBsAg immunologic reactivity and intestinal aerobic flora.","authors":"V Molinari,&nbsp;L Cacciatore,&nbsp;G Cozzolino,&nbsp;M Piazza","doi":"10.1159/000162731","DOIUrl":"https://doi.org/10.1159/000162731","url":null,"abstract":"<p><p>Cultures of human intestinal aerobic flora did not have any inhibiting action on the immunologic reactivity of hepatitis B antigen even after disruption of bacterial cells by freezing and thawing. This suggests that the inhibitor is elaborated by the human intestinal mucosa.</p>","PeriodicalId":19854,"journal":{"name":"Pathologia et microbiologia","volume":"42 2","pages":"127-30"},"PeriodicalIF":0.0,"publicationDate":"1975-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000162731","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12280620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cells involved in the immune response. XXIX Establishment of optimal conditions for the primary and secondary immune responses by rabbit lymphoid cells in vitro. 免疫细胞参与免疫反应的细胞第二十九部分:兔淋巴样细胞体外一次免疫和二次免疫反应最佳条件的建立。
Pathologia et microbiologia Pub Date : 1975-01-01
M Richter, Y Behelak
{"title":"Cells involved in the immune response. XXIX Establishment of optimal conditions for the primary and secondary immune responses by rabbit lymphoid cells in vitro.","authors":"M Richter,&nbsp;Y Behelak","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Attempts were made to initiate the primary and secondary humoral immune responses to sheep red blood cells (SRBC) in vitro as determined by the hemolytic plaque-forming cell (PFC) response, with cell suspensions prepared from a variety of lymphoid organs of the rabbit- thymus, bone marrow, spleen, appendix, sacculus rotundus, Peyer's patches, popliteal lymph node and circulating leukocytes. A number of different media and gaseous phases were utilized in order to establish the optimal conditions for the immune response in vitro. The induction of a secondary PFC response was consistently obtained with 'memory' spleen cells obtained from rabbits 3-6 months following intravenous immunization with SRBC but not with cells of any of the other lymphoid organs, and this response probably represents the activity of memory cells which reside in the rabbit spleen. A primary response was observed only with 'normal' spleen cells, and the medium which faciliated the response was different from that which facilitated the induction of the secondary response in vitro. It was also observed, using a medium in which normal spleen cells were incapable of generating PFC', that mixed cultures of normal spleen and normal appendix or bone marrow cells could give a marked PFC reponse in vitro. Whether the PFC response to SRBCs obtained with the lymphoid cells of normal, unimmunized rabbits represent a true primary response, a secondary response, or a response of a different nature as a consequence of continuous subthreshold immunization of the rabbit with enteric microorganisms which cross-react with the antigen, remains to be determined. However, out initial successes with cultures consisting of cells of at least two distinct lymphoid organs in cases where the cells of any one of these organs could not respond, suggest that interaction of at least two functionally distinct cells is required and that the repsonse observed in vitro is probably a primary immune response.</p>","PeriodicalId":19854,"journal":{"name":"Pathologia et microbiologia","volume":"42 2","pages":"73-91"},"PeriodicalIF":0.0,"publicationDate":"1975-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12280621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[The effect of asbestos cement, UICC asbestos samples and quartz on the peritoneum of the mouse]. [石棉水泥、UICC石棉样品和石英对小鼠腹膜的影响]。
Pathologia et microbiologia Pub Date : 1975-01-01
T Wirth
{"title":"[The effect of asbestos cement, UICC asbestos samples and quartz on the peritoneum of the mouse].","authors":"T Wirth","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Aqueous suspensions of asbestos cement powder injected experimentally into the peritoneal cavity of mice act as a fibrogenic agent, as do chrysotile asbestos or chrysotile asbestos-containing soil samples. The fibrotic nodules caused by the dust resemble morphologically silicosis granulomas. In addition, asbestos cement has a characteristically strong cytotoxic effect during the first 2 weeks of the experiment. It is suggested that this is due to the chrysotile asbestos and/or the calcite component of the powder. Amosite and crocidolite, on the other hand, induce a diffuse peritoneal fibrosis with the appearance of numerous foreign body giant cells and asbestos bodies. Dust particles displaced to the regional lymph nodes are frequent in the animals treated with quartz, asbestos cement and asbestos-containing soil samples. A spindle cell type sarcoma arising from the visceral peritoneum is observed in animals injected with crocidolite or asbestos cement. In addition, dusts containing chrysotile asbestos induce considerable amyloidosis of the liver and spleen.</p>","PeriodicalId":19854,"journal":{"name":"Pathologia et microbiologia","volume":"42 1","pages":"15-28"},"PeriodicalIF":0.0,"publicationDate":"1975-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11387022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Influence of age and sex on carcinoma and cirrhosis of the liver in AXC strain rats ingesting 0.025% N-2-fluorenyldiacetamide. 年龄和性别对摄入0.025% n -2-氟酰二乙酰胺的AXC大鼠肝癌和肝硬化的影响
Pathologia et microbiologia Pub Date : 1975-01-01 DOI: 10.1159/000162792
M D Reuber
{"title":"Influence of age and sex on carcinoma and cirrhosis of the liver in AXC strain rats ingesting 0.025% N-2-fluorenyldiacetamide.","authors":"M D Reuber","doi":"10.1159/000162792","DOIUrl":"https://doi.org/10.1159/000162792","url":null,"abstract":"<p><p>Inbred A X C male and female rats, 4, 12, 24, and 52 weeks of age, ingested 0.025% N-2-fluorenyldiacetamide in a semisynthetic diet. Both age and sex were important in the development of hepatic lesions. The 4- and 12-week-old males developed a higher incidence of carcinomas and cirrhosis of the liver than did the females of the same ages or the males and females 24 and 52 weeks of age. Four-week-old male rats had more carcinomas per liver, larger carcinomas, more poorly differentiated (as compared with well differentiated), and some carcinomas were cholangiocellular as well as hepatocellular. There were a few hepatic lesions in the younger female rats; however, female rats of all ages were relatively resistant to hepatic carcinogenesis.</p>","PeriodicalId":19854,"journal":{"name":"Pathologia et microbiologia","volume":"43 1","pages":"31-7"},"PeriodicalIF":0.0,"publicationDate":"1975-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000162792","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11396250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
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