Pediatric Surgery International最新文献_第2页

Neurodevelopmental disorders in children with congenital abdominal wall defects: a national population-based study. 先天性腹壁缺损儿童的神经发育障碍：一项基于全国人群的研究。

IF 1.6 3区医学

Pediatric Surgery International Pub Date : 2025-09-22 DOI: 10.1007/s00383-025-06201-9

Anna Fogelström, Charlotte Skoglund, Eva Hagel, Tomas Wester, Anna Löf Granström, Carmen Mesas-Burgos

{"title":"Neurodevelopmental disorders in children with congenital abdominal wall defects: a national population-based study.","authors":"Anna Fogelström, Charlotte Skoglund, Eva Hagel, Tomas Wester, Anna Löf Granström, Carmen Mesas-Burgos","doi":"10.1007/s00383-025-06201-9","DOIUrl":"10.1007/s00383-025-06201-9","url":null,"abstract":"Purpose: One in 4000 Swedish children is born with abdominal wall defect (AWD). Little is known about their neurodevelopmental trajectory and long-term morbidity. The aim was to determine the risk of neurodevelopmental disorders in children born with omphalocele or gastroschisis.Methods: This was a population-based national cohort study including children born with omphalocele or gastroschisis in Sweden 1997-2016. Individuals with chromosomal abnormality were excluded. Ten age and sex-matched unexposed individuals were randomly selected for every AWD case. Main outcomes were autism spectrum disorder (ASD) and attention-deficit/hyperactivity disorder (ADHD). Data were collected from the national health registers.Results: During the study period, 496 children were born with AWD and included in the exposed cohorts. The unexposed cohorts consisted of 4943 children. Neurodevelopmental diagnoses were found in 11 (6.1%) children with omphalocele and 15 (4.8%) children with gastroschisis compared to 63 (3.5%) and 113 (3.6%) in the unexposed cohorts (p = 0.096 and p = 0.275). Children with omphalocele had higher risk of ASD (HR = 3.51, 95% CI 1.59-7.78) than unexposed peers (p = 0.02). There was no significant difference in ADHD incidence.Conclusions: Children with AWD may have similar risk of ADHD as age- and sex-matched peers. While the omphalocele cohort had a higher incidence of ASD, the overall incidence remained relatively low.Level of evidence: II.","PeriodicalId":19832,"journal":{"name":"Pediatric Surgery International","volume":"41 1","pages":"303"},"PeriodicalIF":1.6,"publicationDate":"2025-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12454545/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145125634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Androgen receptor expression in the foreskin of children born with hypospadias: a systematic review. 尿道下裂患儿包皮中雄激素受体的表达：一项系统综述。

IF 1.6 3区医学

Pediatric Surgery International Pub Date : 2025-09-21 DOI: 10.1007/s00383-025-06205-5

Fiyinfoluwa Timothy Oladipo, Ilhama Jafarli, İrada Huseynova, Heidi E Reynolds

{"title":"Androgen receptor expression in the foreskin of children born with hypospadias: a systematic review.","authors":"Fiyinfoluwa Timothy Oladipo, Ilhama Jafarli, İrada Huseynova, Heidi E Reynolds","doi":"10.1007/s00383-025-06205-5","DOIUrl":"10.1007/s00383-025-06205-5","url":null,"abstract":"Hypospadias is a congenital malformation of the penis affecting 1 in every 250 male births. Measurement of androgen receptor (AR) levels in the foreskin has been used to elucidate the role of this receptor in the hypospadias aetiology. This review evaluates the extent of immunohistochemical AR expression in the foreskin of boys with hypospadias, compared to their unaffected counterparts. Several databases (MEDLINE, Embase, and The Cochrane library) were searched to find studies relevant to our research question. From 657 studies, 24 underwent full-text review, and 8 were included in a narrative synthesis analysis of the findings reported by the literature. Four studies reported significantly increased quantified AR expression in hypospadias (p < 0.05), while three described significantly decreased expression (p < 0.013), and one reported no significant difference between groups. Furthermore, AR expression was found to be higher in the stroma of the foreskin than the epithelium. No clear consensus has been established regarding the relationship between AR expression and hypospadias in the literature. This may be due to variability in the age of participants included in the study, or additional factors such as genetic conditions, highlighting the need for a standard approach to investigation. Registration: This systematic review was registered under PROSPERO identification number CRD420251000803.","PeriodicalId":19832,"journal":{"name":"Pediatric Surgery International","volume":"41 1","pages":"301"},"PeriodicalIF":1.6,"publicationDate":"2025-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145113998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Correction: Reoperation related to Roux-en-Y jejunal limb after hepaticojejunostomy of choledochal cyst. 纠正：胆总管囊肿肝空肠吻合术后Roux-en-Y空肠肢体再手术。

IF 1.6 3区医学

Pediatric Surgery International Pub Date : 2025-09-20 DOI: 10.1007/s00383-025-06203-7

Anxiao Ming, Yifeng Shao, Mei Diao, Qi Li, Xu Li, Long Li

引用次数: 0

Assesment of factors affecting outcome of Mini-PCNL by single-shot dilatation in Pediatric Patients. 儿科患者单次扩张Mini-PCNL疗效的影响因素评估。

IF 1.6 3区医学

Pediatric Surgery International Pub Date : 2025-09-18 DOI: 10.1007/s00383-025-06198-1

Kadir Emre Baltaci, Berk Hazir, Mesut Altan, Ali Cansu Bozaci, Kamranbay Gasimov, Serdar Tekgul, Hasan Serkan Doğan

{"title":"Assesment of factors affecting outcome of Mini-PCNL by single-shot dilatation in Pediatric Patients.","authors":"Kadir Emre Baltaci, Berk Hazir, Mesut Altan, Ali Cansu Bozaci, Kamranbay Gasimov, Serdar Tekgul, Hasan Serkan Doğan","doi":"10.1007/s00383-025-06198-1","DOIUrl":"https://doi.org/10.1007/s00383-025-06198-1","url":null,"abstract":"Objectives: The prevalence of stone disease in children is increasing, necessitating approaches using instruments of more suitable sizes for surgical treatment. We aim to convey our experience with Mini-PCNL.Materials and methods: We retrospectively analyzed a total of 72 renal units that underwent single-shot dilatation Mini-PCNL(≤ 17.5F) between August 2017 and November 2024. Univariate and multivariate analyses were used to assess the factors for surgical success (no postoperative residual) and complications.Results: Medians for our cohort were age at surgery was 5.5 years, operation time was 120 min, hospitalization time was 5 days, stone size was 2.04 cm2. Overall SFR was 80.6%. We observed complications in 16 patients(%22.2). In univariate analysis; HU < 820, PCNL history, cystine stone, stone burden > 2 cm2 and stone length > 29 mm were found to be associated with lower success. In the multivariate analysis results, patients with a previous history of PCNL (56% vs 93.6%) (p = 0.005) and patients with a stone burden ≥ 2 cm2 (68.4% vs 94.1%) (p = 0.021) were found to be associated with less successful results. Univariate analysis revealed no single predictive factor for complication development.Conclusion: Mini-PCNL is a surgical method that can be performed safely in the pediatric age group due to its high stone-free rate. However, it should be kept in mind that the success rates are lower in those with a history of PCNL due to anatomical challenges secondary to previous surgeries and with high stone burden. Patients with cystine stones deserve more effort to make them free of fragments.","PeriodicalId":19832,"journal":{"name":"Pediatric Surgery International","volume":"41 1","pages":"299"},"PeriodicalIF":1.6,"publicationDate":"2025-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145081358","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Parental attitudes to neoanus dilatations post-reconstruction in anorectal malformations (PANDA) study. 父母对肛肠畸形重建后新肛门扩张的态度（PANDA）研究。

IF 1.6 3区医学

Pediatric Surgery International Pub Date : 2025-09-17 DOI: 10.1007/s00383-025-06190-9

H Thakkar, V Haffenden, S Yardley

{"title":"Parental attitudes to neoanus dilatations post-reconstruction in anorectal malformations (PANDA) study.","authors":"H Thakkar, V Haffenden, S Yardley","doi":"10.1007/s00383-025-06190-9","DOIUrl":"10.1007/s00383-025-06190-9","url":null,"abstract":"Purpose: Some surgeons train parents to undertake routine neoanus dilatations following anorectal malformation surgery. Recent studies suggest this may not significantly reduce the incidence of strictures. This study sought to understand parental experiences of and perceptions about this intervention to guide best practise and inform further studies of clinical impact.Methods: This qualitative study, using reflexive thematic analysis was carried out in a single institution. Five parents took part in an audio-recorded focus group with 13 families subsequently taking part in audio-recorded semi-structured interviews. Concurrent analysis of verbatim transcripts guided iterations in data generation.Results: Four major themes were identified; (1) parents understood the importance of dilatations; (2) parents experienced distress with anxiety, fear of causing harm and guilt; (3) parents perceived a traumatic reaction from infants including anticipatory stress; and (4) some parents perceived detrimental impact on inter-parental relationships with an imbalance in responsibilities for dilatations.Conclusions: Parents who accept the importance of dilatations, are placing trust in their clinicians' guidance despite their negative experiences of the intervention and perceived relational costs between themselves and their child. As the quantitative clinical evidence for neoanus dilatation remains, at best, equivocal, we do not recommend routine dilatations post-reconstructive surgery for anorectal malformations.","PeriodicalId":19832,"journal":{"name":"Pediatric Surgery International","volume":"41 1","pages":"296"},"PeriodicalIF":1.6,"publicationDate":"2025-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12443886/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145075770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Postoperative complications following surgery for congenital hyperinsulinism and insulinomas in pediatric patients. 小儿先天性高胰岛素血症和胰岛素瘤手术后并发症。

IF 1.6 3区医学

Pediatric Surgery International Pub Date : 2025-09-17 DOI: 10.1007/s00383-025-06191-8

Gregers Gaardskær Boel, Henrik Thybo Christesen, Mark Bremholm Ellebæk, Michael Bau Mortensen

{"title":"Postoperative complications following surgery for congenital hyperinsulinism and insulinomas in pediatric patients.","authors":"Gregers Gaardskær Boel, Henrik Thybo Christesen, Mark Bremholm Ellebæk, Michael Bau Mortensen","doi":"10.1007/s00383-025-06191-8","DOIUrl":"10.1007/s00383-025-06191-8","url":null,"abstract":"Purpose: To systematically describe postoperative complications in surgery for HI in pediatric patients.Methods: In this retrospective single-center study, we systematically analyzed the rate and grade of complications according to the Comprehensive Complication Index (CCI), Clavien-Dindo Classification (CDC), and the Clavien-Madadi Classification (CMC) in 74 patients undergoing a total of 89 surgeries for CHI (N = 68) or pediatric insulinomas (N = 6) at Odense University Hospital, Denmark, from 01.01.2010 until 01.10.2024.Results: Patients surgically treated for focal CHI had more favorable surgical outcomes with a mean CCI score of 10.8 vs. the diffuse CHI mean CCI of 26.3 (p = 0.0018). Surgical treatment for pediatric insulinomas resulted in a mean CCI of 28.9. In the total group, the most common complication was postoperative infection (29%), followed by delayed gastric emptying (20%). The rate of postoperative pancreatic fistula was 11%, but only 3.4% were clinically relevant. Eight percent of the surgical procedures resulted in complications classified as CMD grade IIIb or higher.Conclusion: Despite the complex nature of surgery in pediatric patients with CHI or insulinomas, the majority had an uneventful recovery. Severe complications (CMC grade IIIb +) were, however, seen in 8%. Prospective, systematic postoperative complication score evaluation is encouraged in surgery for pediatric HI.","PeriodicalId":19832,"journal":{"name":"Pediatric Surgery International","volume":"41 1","pages":"298"},"PeriodicalIF":1.6,"publicationDate":"2025-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12443887/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145075849","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Is obesity a protective factor in pediatric trauma? A retrospective review in a tertiary trauma centre over the decade. 肥胖是儿童创伤的保护因素吗？在一个三级创伤中心回顾过去的十年。

IF 1.6 3区医学

Pediatric Surgery International Pub Date : 2025-09-17 DOI: 10.1007/s00383-025-06193-6

Phoenix W Y Wong, Kenneth K Y Wong

{"title":"Is obesity a protective factor in pediatric trauma? A retrospective review in a tertiary trauma centre over the decade.","authors":"Phoenix W Y Wong, Kenneth K Y Wong","doi":"10.1007/s00383-025-06193-6","DOIUrl":"10.1007/s00383-025-06193-6","url":null,"abstract":"Purpose: The obesity paradox has been demonstrated in the adult trauma population. Yet there are conflicting results in children. The study aims to investigate the effect of childhood obesity on the outcomes after sustaining trauma.Method: All children (< 18-year-old) who attended a tertiary trauma centre from January 2010 to March 2022 due to impact trauma were included. The obese group was defined by a body weight > 95th percentile for age, and others were in the non-obese group. Outcomes, including injury-severity-scores (ISS), morbidity/mortality and length-of-stay (LOS), were compared between the groups. Subgroup analyses were performed on causes of injury and age groups. Severe injury was defined by ISS > 15.Results: 148 subjects were included in the analysis (23 in the obese group; 123 in the non-obese group). They were similar in terms of injury causes and outcomes. The obese group had longer LOS (4 days vs 2 days, p = 0.022), and a higher proportion of them had severe injuries when < 11-year-old (28.6% vs 9%, p = 0.034).Conclusion: In contrast to adults, childhood obesity appears not to be a protective factor in trauma, and may be a risk factor, especially in younger children, for more severe injuries. Careful evaluation of obese children sustaining trauma is warranted to prevent injuries from being overlooked.","PeriodicalId":19832,"journal":{"name":"Pediatric Surgery International","volume":"41 1","pages":"297"},"PeriodicalIF":1.6,"publicationDate":"2025-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12443894/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145075739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical characteristics and outcomes of anterior anus in female infants: a multicenter retrospective cohort study. 女婴前肛门的临床特征和预后：一项多中心回顾性队列研究。

IF 1.6 3区医学

Pediatric Surgery International Pub Date : 2025-09-16 DOI: 10.1007/s00383-025-06196-3

Yong Jae Kwon, Hyunhee Kwon, Suhyeon Ha, Dae Yeon Kim, Yu Jeong Cho, Ju Yeon Lee, So Hyun Nam, Eunyoung Jung

{"title":"Clinical characteristics and outcomes of anterior anus in female infants: a multicenter retrospective cohort study.","authors":"Yong Jae Kwon, Hyunhee Kwon, Suhyeon Ha, Dae Yeon Kim, Yu Jeong Cho, Ju Yeon Lee, So Hyun Nam, Eunyoung Jung","doi":"10.1007/s00383-025-06196-3","DOIUrl":"10.1007/s00383-025-06196-3","url":null,"abstract":"Background: Anterior anus (AA) is a congenital anatomical variant with unclear clinical implications and management strategies. This study evaluated the clinical features, associated anomalies, and outcomes of AA in female infants.Methods: This multicenter retrospective cohort study included infants diagnosed with AA between 2020 and 2024 at six tertiary referral centers in South Korea. The clinical characteristics, coexisting anomalies, and outcomes including constipation and urinary tract infections were analyzed.Results: Among the 64 patients included in this study, 51.6% had a concomitant perineal groove. Congenital heart diseases were the most common coexisting anomaly, occurring in 32 patients. During a mean follow-up of 22.9 months, constipation was observed in 23% of the patients. Urinary tract infections were not observed. The perineal groove resolved spontaneously in 87.9% of cases.Conclusion: AA is a benign anatomical variant that does not increase the risk of constipation or urinary tract infections. Given the observed association with congenital heart disease, cardiac evaluation should be considered when clinically indicated.","PeriodicalId":19832,"journal":{"name":"Pediatric Surgery International","volume":"41 1","pages":"295"},"PeriodicalIF":1.6,"publicationDate":"2025-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145075724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Thoracoscopic internal traction for long-gap esophageal atresia: outcomes, challenges, and complications. 胸腔镜内牵引治疗长间隙食管闭锁：结果、挑战和并发症。

IF 1.6 3区医学

Pediatric Surgery International Pub Date : 2025-09-15 DOI: 10.1007/s00383-025-06186-5

Ulgen Celtik, Cengiz Sahutoglu, Coskun Ozcan, Zafer Dokumcu

{"title":"Thoracoscopic internal traction for long-gap esophageal atresia: outcomes, challenges, and complications.","authors":"Ulgen Celtik, Cengiz Sahutoglu, Coskun Ozcan, Zafer Dokumcu","doi":"10.1007/s00383-025-06186-5","DOIUrl":"10.1007/s00383-025-06186-5","url":null,"abstract":"Aim: To evaluate our institutional experience with thoracoscopic staged repair with internal traction (TSRIT) in the management of long-gap esophageal atresia (LGEA), focusing on surgical techniques, early and late outcomes, and functional results.Method: Between 2019 and 2024, EA patients who underwent TSIRT in LGEA were retrospectively reviewed. Demographics, surgical details, and early and late complications were collected. Early-late complications were compared between groups. Causes of traction failure and complications were examined. Swallowing function was assessed using the Pediatric EAT-10 score.Results: Thirteen patients (Type A/B:5/8) underwent TSIRT. Traction failed in three cases (Type A/B:1/2), and these patients were referred to replacement surgery. Definitive anastomosis was successfully achieved in 10 of 13 patients. In 3 cases, traction failed due to technical or anatomical factors. Early complications included 4 anastomotic leaks (A/B:3/1) and 2 strictures(A/B:0/2); all were managed conservatively. Late complications included mild anastomotic strictures in 5 patients(A/B:1/4) and gastroesophageal reflux in 3(A/B:0/3), none of whom required fundoplication. All patients demonstrated adequate growth during follow-up, and most achieved satisfactory oral intake. The medium follow-up time was similar between the groups, with a mean follow-up duration of 30 months.Conclusion: In the long-term follow-up, the majority of patients demonstrated good oral intake. The failure rate was 23%. While no statistically significant difference was observed between the groups regarding early and late complications, the higher incidence of complications in the Type B group suggests that these patients require closer monitoring and more meticulous management.","PeriodicalId":19832,"journal":{"name":"Pediatric Surgery International","volume":"41 1","pages":"294"},"PeriodicalIF":1.6,"publicationDate":"2025-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145065127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pooling one study is not a meta-analysis. 汇集一项研究并不是荟萃分析。

IF 1.6 3区医学

Pediatric Surgery International Pub Date : 2025-09-14 DOI: 10.1007/s00383-025-06192-7

Javier Arredondo Montero

引用次数: 0