Pathophysiology of Haemostasis and Thrombosis最新文献_第4页

An experience of oseltamivir phosphate (tamiflu™) in a pediatric patient with chronic idiopathic thrombocytopenic purpura: a case report. 磷酸奥司他韦(达菲™)治疗儿童慢性特发性血小板减少性紫癜的经验:1例报告。

Pathophysiology of Haemostasis and Thrombosis Pub Date : 2010-01-01 Epub Date: 2010-11-09 DOI: 10.1159/000321379

Bulent Alioglu, Aysin Tasar, Cinar Ozen, Beray Selver, Yildiz Dallar

引用次数: 34

Title Page / Table of Contents 标题页/目录

Pathophysiology of Haemostasis and Thrombosis Pub Date : 2009-01-01 DOI: 10.1159/000198248

引用次数: 0

Author Index Vol. 36, No. 3–4, 2007–08 作者索引第36卷第3-4期，2007-08

Pathophysiology of Haemostasis and Thrombosis Pub Date : 2009-01-01 DOI: 10.1159/000198177

引用次数: 0

Subject Index Vol. 36, No. 3–4, 2007–08 主题索引第36卷，第3-4期，2007-08

Pathophysiology of Haemostasis and Thrombosis Pub Date : 2009-01-01 DOI: 10.1159/000198240

引用次数: 0

Plenary Lectures 大型讲座

Pathophysiology of Haemostasis and Thrombosis Pub Date : 2008-06-01 DOI: 10.1159/000142053

R. Dijkgraaf, H. Föllmer, H. Lenstra, Manin, Y. Meyer, C. Simó, M. Vigneras, O. Viro, A. Wiles

引用次数: 0

Oral Presentations 口头报告

Pathophysiology of Haemostasis and Thrombosis Pub Date : 2008-06-01 DOI: 10.1159/000142056

J. Bellos, M. Moschou, E. Avgerinos, A. Kostakis, K. Mahmoodi, Joost Brouwer, N. Veeger, J. Meer, T. Severinsen, S. Kristensen, S. Johnsen, C. Dethlefsen, A. Tjønneland, K. Overvad, J. Saour, A. Sheereen, M. Shoukri, T. Saou’r, L. Mammo

引用次数: 0

Effects of alteplase, a thrombolytic agent, in a rat photothrombotic middle cerebral artery occlusion model. 溶栓剂阿替普酶在大鼠光血栓性大脑中动脉闭塞模型中的作用。

Pathophysiology of Haemostasis and Thrombosis Pub Date : 2008-01-01 Epub Date: 2009-12-09 DOI: 10.1159/000252820

Kazuo Umemura, Katsuya Higo, Takeshi Sakata, Satoshi Yuki, Koji Iwata, Kazumasa Yamaguchi

引用次数: 6

Granulocyte colony-stimulating factor increases the platelet volume in peripheral stem cell apheresis donors. 粒细胞集落刺激因子增加外周血干细胞分离供者血小板体积。

Pathophysiology of Haemostasis and Thrombosis Pub Date : 2008-01-01 Epub Date: 2009-12-09 DOI: 10.1159/000252823

Akihiro Ihara, Keiko Matsui, Ryouta Minami, Shuzou Uchida, Shuji Ueda, Tetsuo Nishiura

{"title":"Granulocyte colony-stimulating factor increases the platelet volume in peripheral stem cell apheresis donors.","authors":"Akihiro Ihara, Keiko Matsui, Ryouta Minami, Shuzou Uchida, Shuji Ueda, Tetsuo Nishiura","doi":"10.1159/000252823","DOIUrl":"https://doi.org/10.1159/000252823","url":null,"abstract":"We investigated the short-term influence of granulocyte colony-stimulating factor (G-CSF) administration on platelet counts and platelet indices in 12 donors (8 males and 4 females; median age 34 years, range 16-49) for peripheral stem cell transplantation using an automated blood cell analyzer. On day 3 (D3) compared with D0, 11 donors with normal laboratory and physical findings showed increases in platelet indices (chi(2) = 12.0, p = 0.0025). Furthermore, mean platelet volume (MPV) was significantly increased (p = 0.04). Also, platelet count decreased, and platelet distribution width and platelet-large cell ratio were increased, but these were not significant. On the contrary, 1 donor with abnormal laboratory findings who had large platelets (MPV 11.4 fl) before G-CSF administration showed decreases in platelet indices (MPV 10.3 fl) on D3, although platelet count (18.2 x 10(4)/microl) decreased after G-CSF administration. G-CSF administration induces an inflammatory process with endothelial cell activation. This is probably the reason why platelet volume increases after G-CSF use. This is the first report showing that G-CSF administration immediately induces increases in large platelets in peripheral stem cell transplant donors before harvest.","PeriodicalId":19817,"journal":{"name":"Pathophysiology of Haemostasis and Thrombosis","volume":"36 5","pages":"266-70"},"PeriodicalIF":0.0,"publicationDate":"2008-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000252823","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"28582579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Leukocytosis, JAK2V617F mutation, and hemostasis in myeloproliferative disorders. 骨髓增生性疾病中的白细胞增多、JAK2V617F突变和止血。

Pathophysiology of Haemostasis and Thrombosis Pub Date : 2008-01-01 Epub Date: 2009-01-27 DOI: 10.1159/000175153

Marina Marchetti, Anna Falanga

{"title":"Leukocytosis, JAK2V617F mutation, and hemostasis in myeloproliferative disorders.","authors":"Marina Marchetti, Anna Falanga","doi":"10.1159/000175153","DOIUrl":"https://doi.org/10.1159/000175153","url":null,"abstract":"Thrombosis is a leading cause of morbidity and mortality in patients with essential thrombocythemia (ET) and polycythemia vera (PV). Several mechanisms have been proposed to cause or to contribute to the acquired thrombophilic state of these patients, including platelet and red blood cell abnormalities. The increase in white blood cell count, found in most subjects with these disorders, raises the possibility that circulating leukocytes may represent another prothrombotic factor, as demonstrated for other conditions, including sickle cell, coronary heart, and peripheral arterial diseases. Published data demonstrate that neutrophil activation occurs in ET and PV patients in parallel with the appearance of laboratory signs of hemostatic system activation, suggesting an involvement of these cells in the pathogenesis of the thrombotic predisposition of these subjects. In 2005, an acquired point mutation in the pseudokinase domain of Janus kinase 2 (JAK2(V617F)) has been described in these disorders, and has attracted an enormous interest both as a diagnostic and prognostic tool, and as a potential therapeutic target. Retrospective data have identified JAK2(V617F) as a risk factor for thrombosis in ET, and have also shown a close association with abdominal vein thrombosis. JAK2(V617F) is variably associated with thrombosis and, more consistently, with elevations in blood cell counts. A clear link appears to exist between leukocytosis, JAK2(V617F), and the hemostatic system activation in patients with Bcl-negative myeloproliferative disorders.","PeriodicalId":19817,"journal":{"name":"Pathophysiology of Haemostasis and Thrombosis","volume":"36 3-4","pages":"148-59"},"PeriodicalIF":0.0,"publicationDate":"2008-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000175153","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"27952324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 47

Regulation of ADAMTS13 expression in proliferating human umbilical vein endothelial cells. 增殖的人脐静脉内皮细胞ADAMTS13表达的调控。

Pathophysiology of Haemostasis and Thrombosis Pub Date : 2008-01-01 Epub Date: 2009-12-09 DOI: 10.1159/000252818

Stephen J Kling, Cambria A Judd, Keith B Warner, George M Rodgers

引用次数: 10