Pain Clinic最新文献

{"title":"Reliability and validity of the pain threshold measurement with the Dolorímetro Electrónico Portátil ® (Portable Electronic Dolorimeter) in healthy individuals and patients with musculoskeletal pain","authors":"Esmeralda García-Fernández, Juan F. Godoy-Garcia, J. Jiménez-Alonso, D. Godoy-Izquierdo, M. Pérez-García, I. López-Chicheri","doi":"10.1179/016911106779498984","DOIUrl":"https://doi.org/10.1179/016911106779498984","url":null,"abstract":"Abstract Aims: The objective of this study was to establish the reliability and validity of the measurement of the pressure pain threshold using the Dolorimetro Electronico Portatil (Portable Electronic Dolorimeter) (DEP®) in persons without pain (12 men and 18 women) and in patients with chronic pain (16 women with systemic lupus erythematosus, 16 women with fibromyalgia and 15 women with rheumatoid arthritis). Methods: The assessment of the pressure pain threshold using the DEP® was done over three sessions with a 15 minute interval between the first and second session, and a 7 day interval between the second and third session. Each session comprised two trials in which 24 pressure points were evaluated. Results: Regarding reliability, high correlation coefficients were obtained in the three temporal conditions (within sessions without interval: ρ = 0.922, p < 0.001; inmediate, or brief interval between sessions (15 min): ρ = 0.932, p < 0.001; demorated, or long interval between sessions (7 days): ρ = 0...","PeriodicalId":19808,"journal":{"name":"Pain Clinic","volume":"14 1","pages":"377-386"},"PeriodicalIF":0.0,"publicationDate":"2006-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89503785","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A dose–response study of prostaglandin E1 on nerve root blood flow velocity and neurologic symptoms after lumbar spinal decompression in surgical patients","authors":"M. Fukusaki, M. Miyako, C. Inadomi, K. Yamashita, Y. Terao, K. Sumikawa","doi":"10.1163/156856906778704641","DOIUrl":"https://doi.org/10.1163/156856906778704641","url":null,"abstract":"Abstract Aim: This study was carried out to determine the dose–response relationship of the effects of prostaglandin E1 (PGE1) on the nerve root blood flow and the neurologic symptoms after lumbar decompressive surgery using laser Doppler flowmetry. Methods: Fifty-four patients undergoing lumbar laminectomy were randomly assigned to one of three groups. Each group received intravenously one of three test solutions; 10 ml of saline in group A (N = 18), 10 ml of saline containing PGE1, 20 μg, in group B (N = 18), and 10 ml of saline containing PGE1, 50 μg, in group C (N = 18). After lumbar laminectomy, a probe of laser Doppler flowmetry was placed directly on the lumbar nerve root. Nerve root blood flow (RBF) velocity was measured before the injection of test solution (T1), at 5 min (T2) and 10 min (T3) after starting injection, and 10 min after the end of injection (T4). A visual analogue scale (VAS) and the walking distance were measured for assessment of neurologic symptoms before and after surgery. Resu...","PeriodicalId":19808,"journal":{"name":"Pain Clinic","volume":"17 1","pages":"287-295"},"PeriodicalIF":0.0,"publicationDate":"2006-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74844309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Microbiological analysis of root canals associated with periapical abscesses (with pain and swelling) and the antimicrobial susceptibility of isolated bacteria","authors":"S. M. Ozbek, M. S. Evcil, A. Ozbek, A. Erdoğan, M. Köseoğlu","doi":"10.1163/156856906778704632","DOIUrl":"https://doi.org/10.1163/156856906778704632","url":null,"abstract":"Abstract Objective: The periapical abscess is a collection of pus in the pulp or around the root of teeth. Many odontogenic infections can be managed without antimicrobial therapy or bacteriologic investigation. However, when an acute bacterial infection has progressed or antimicrobial therapy might be of benefit to patients, antibiotics are prescribed. We aimed to identify microorganisms in root canals with periapical abscess and their antimicrobial susceptibility profile in order to revise antimicrobial treatment protocols when antimicrobials are used empirically. Methods: 30 patients (all of whom had pain and swelling) with odontogenic infections were included in this study. The microbiologic investigation was performed under strict aseptic conditions. A standard routine root canal therapy was instituted, and in each case a single root canal was sampled. In multirooted teeth only the largest canal was sampled to preserve the identity of a single endodontic/microbiologic ecosystem. For microbial samplin...","PeriodicalId":19808,"journal":{"name":"Pain Clinic","volume":"70 1","pages":"327-337"},"PeriodicalIF":0.0,"publicationDate":"2006-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86388615","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ultrastructural findings of idiopathic trigeminal neuralgia","authors":"Zhaoxin Ma, Ming Li, Ling Qi","doi":"10.1163/156856906778704650","DOIUrl":"https://doi.org/10.1163/156856906778704650","url":null,"abstract":"Abstract Objective: To further investigate the ultrastructural features of trigeminal nerve root in patients with trigeminal neuralgia without vascular compression. Methods: Trigeminal nerve root biopsy specimens were excised from 12 patients scheduled to undergo posterior fossa craniotomy and root exploration. In 12 of 106 patients no vascular compression was detected. Partial trigeminal posterior rhizotomy was performed. A biopsy sample was taken from the cut portion of the root, followed by electron microscopic examination. Results: The primary finding was the pronounced involvement of the myelin sheath and Schwann cells. In 10 out of 12 specimens, there were some claviform steroid crystals in the Schwann cell cytoplasm. Myelin filled came to fill the liposomes. In all specimens, dysmyelination and demyelination were the main changes of the myelin sheath. Conclusion: Claviform steroid crystals in Schwann cell cytoplasm and lipid deposition in the inner myelin sheath of trigeminal root were found.","PeriodicalId":19808,"journal":{"name":"Pain Clinic","volume":"7 1","pages":"339-344"},"PeriodicalIF":0.0,"publicationDate":"2006-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76723313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Neuropathic pain with case examples and current therapeutic approaches","authors":"A. O. Bayrak, H. Türker, M. Onar","doi":"10.1179/016911106779499055","DOIUrl":"https://doi.org/10.1179/016911106779499055","url":null,"abstract":"AbstractNeuropathic pain is by definition a chronic pain initiated or caused by a primary lesion or dysfunction of the peripheral or central nervous system. Since multiple complex pathophysiological mechanisms are supposed to be the cause for neuropathic pain, therapeutic approaches vary among physicians. In this article we report three cases with neuropathic pain and discuss therapeutic approaches with current trends while pointing out some important problems arising in everyday practice.","PeriodicalId":19808,"journal":{"name":"Pain Clinic","volume":"41 1","pages":"387-393"},"PeriodicalIF":0.0,"publicationDate":"2006-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85752723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Milnacipran hydrochloride for the treatment of postherpetic neuralgia","authors":"M. Komori, A. Fukuuchi, Tomoko Mae, K. Nishiyama, M. Kawamata, M. Ozaki","doi":"10.1179/016911106779498966","DOIUrl":"https://doi.org/10.1179/016911106779498966","url":null,"abstract":"AbstractWe studied the effect of milnacipran hydrochloride, a newly developed serotonin-noradrenaline-reuptake-inhibitor antidepressant with minimal side effects, in 12 patients with postherpetic neuralgia. All patients had a pain score of at least 40 on a visual-analogue scale (VAS) ranging from 0 (no pain) to 100 (worst pain possible), 3 months after the resolution of herpes zoster. Their pain did not respond to nerve blocks and could not be adequately controlled by currently used drugs. Milnacipran was given at an initial dose of 15 mg/day. The dose was then adjusted according to symptoms. The mean VAS score after 8 weeks of treatment with milnacipran (28.0 ± 17.5) significantly decreased, as compared with the baseline value (68.0 ± 16.9, p < 0.05). The mean daily dose of milnacipran was 52.0 ± 35.1 mg. No relevant side effects were observed. We conclude that milnacipran is useful in patients with postherpetic neuralgia refractory to conventional treatment.","PeriodicalId":19808,"journal":{"name":"Pain Clinic","volume":"19 1","pages":"421-423"},"PeriodicalIF":0.0,"publicationDate":"2006-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85956242","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ewing's sarcoma of the pelvic girdle mimicking the unilateral sacroiliitis and lumbar disc syndrome: Case report","authors":"B. Balaban, M. Taşkaynatan, Serhat Gencdogan, A. Özgül, A. Tan, T. Kalyon","doi":"10.1163/156856906778026220","DOIUrl":"https://doi.org/10.1163/156856906778026220","url":null,"abstract":"AbstractEwing's sarcoma is one of the most common malignant tumors of the musculoskeletal system in children, adolescents and young adults. Early recognition of this sarcoma and early treatment improves outcome. In the event of pelvic involvement, patients may have spinal symptoms and radiographic findings similar to discogenic pain or sacroiliitis. In this report. a 21-year-old male, who had clinical features mimicking unilateral sacroiliitis and lumbar disc syndrome, is described. His advanced radiographic evaluation and biopsy demonstrated Ewing's sarcoma of the pelvic girdle. Pelvic tumors in the differential diagnosis of low back pain are discussed.","PeriodicalId":19808,"journal":{"name":"Pain Clinic","volume":"92 1","pages":"259-262"},"PeriodicalIF":0.0,"publicationDate":"2006-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80421155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparing analgesic effect of intra-articular neostigmine, tramadol and tenoxicam with placebo","authors":"P. Kirdemi̇r, A. Marsan, V. Kırdemir","doi":"10.1163/156856906778026176","DOIUrl":"https://doi.org/10.1163/156856906778026176","url":null,"abstract":"Abstract Purpose: To compare post-operative analgesic effects of intra-articular (i.a.) drugs. Methods: After the approval of ethic committee, a randomized study on 68 patients undergoing knee arthroscopy was performed. In Group I (n = 16) 0.5 mg of neostigmine, in Group II (n = 14) 100 mg of tradamol, in Group III (n = 20) 20 mg of tenoxicam in 20 ml 0.9% NaCl solution and Group P (n = 18) 20 ml of 0.9% NaCl were injected i.a. at the end of the arthroscopy. The visual analogue scale, heart rate (HR), mean arterial pressure (MAP) values and side effects were recorded at intervals of 1, 2, 6 and 24 hours after the operation. Patient's satisfaction was also recorded. Results: The duration of analgesia in Group I was significantly longer than in the other groups. In Group III patients' satisfaction was excellent. One patient in Group I and Group II had nausea, one patient in Group II had somnolence. Conclusion: All drugs provided acceptable post-operative analgesia with excellent satisfaction in Group III. A...","PeriodicalId":19808,"journal":{"name":"Pain Clinic","volume":"44 1","pages":"231-236"},"PeriodicalIF":0.0,"publicationDate":"2006-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83039233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A new definition of 'pain': an imperative of our times","authors":"E. Ibarra","doi":"10.1163/156856906778026185","DOIUrl":"https://doi.org/10.1163/156856906778026185","url":null,"abstract":"Over the past fifty years, the subject of pain and its management has gained worldwide recognition, not only as a medical specialty, but also as a subject for both scientific research and philosophical analysis. In keeping with this interest, a number of approaches from a variety of disciplines have been considered, studied and/or developed, in an attempt to further a scientific and humanitarian understanding of the condition and optimize the treatment thereof. These approaches include the bio-psychological approach, multidisciplinary treatment, theories on modulation, the palliative approach, pain behavior methodology, and the use of psychological strategies. In addition, studies on membrane channels and receptors, neuropathic pain states and their changes within the nervous system, disruption using chemical agents on the channels involved in pain transmission, disruption of RNA transcription, the chemical alteration of central processes, the use of implantable neuromodulators, infusion devices, intradiscal interventions, radiofrequency related technologies and many more, bring us closer to understanding the phenomenon of pain and how it can be more effectively prevented, managed or eliminated. Many of the advances made in the area of pain understanding and treatment are due to the invaluable contributions and dedication of such great people as John Bonica,1 Romald Melzack,2 Patrick Wall,2 Prithvi Raj,3 Menno E. Sluijter,4 Gabor Racz5 and Ricardo Plancarte,6 to name just a few. However, let us not forget the humble professional who treats pain with the means available to him or her, and does so without appearing in the forum of the world-renowned. The work of these individuals undoubtedly deserves much admiration, respect and recognition. In addition, many other disciplines have contributed with valuable studies on the subject of pain, which offer the perspective of its broad implications in all aspects of society and on the general quality of human life. Most recently, a humanistic and legal analysis, recognizing pain as the most terrible flagellation of mankind since its origins7 and as a disease in its own right8 brought about worldwide recognition of the related proposition for the recognition of the Treatment of Pain as a Fundamental Human Right. The above brings deserved justice to fathers of the Universal Declaration of Human Rights9 on their awareness and recognition of human suffering due to pain, and the implicit inclusion of the right to its treatment within the right","PeriodicalId":19808,"journal":{"name":"Pain Clinic","volume":"19 7 1","pages":"277-282"},"PeriodicalIF":0.0,"publicationDate":"2006-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86563281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Botulinum toxin in management of neuroma pain: case report","authors":"A. Tiwari, A. Singh, R. Verma, V. Rastogi, R. Agrawal","doi":"10.1163/156856906778026112","DOIUrl":"https://doi.org/10.1163/156856906778026112","url":null,"abstract":"AbstractNeuroma is a painful condition and always a challenging situation for pain clinicians. Botulinum toxin (BoNT) is a neurotoxin and it provides analgesia, possibly by inhibiting acetylcholine release or blocking autonomic pathways. We report two interesting cases of neuroma in which botulinum toxin (BoNT) serotype-A was locally infiltrated (10 units into the trigger point), three times after an interval of one month each. We observed relief of pain after 10 days and a complete remission after 4 months.","PeriodicalId":19808,"journal":{"name":"Pain Clinic","volume":"68 1","pages":"263-265"},"PeriodicalIF":0.0,"publicationDate":"2006-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81677267","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}