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Pain therapy in multiple myeloma — clinical experience from an observational study 多发性骨髓瘤的疼痛治疗——一项观察性研究的临床经验
Pain Clinic Pub Date : 2006-04-01 DOI: 10.1163/156856906776760380
H. Lannert
{"title":"Pain therapy in multiple myeloma — clinical experience from an observational study","authors":"H. Lannert","doi":"10.1163/156856906776760380","DOIUrl":"https://doi.org/10.1163/156856906776760380","url":null,"abstract":"Abstract Aim: The aim of the present study was the documentation and evaluation of analgesic therapy in patients with multiple myeloma. Method: As part of a chemotherapy optimisation study, the patients' pain therapy was documented. The severity of pain was recorded using a visual analogue scale (VAS) from 0 (neither pain nor impairment) to 10 (greatest imaginable pain, and very severe impairment). Follow-up examinations took place after 3 days, 1 month and 3 months. Results: 123 patients (60.9%) of 202 patients with multiple myeloma stage III, were treated with analgesics because of severe pain. The average duration of documentation was 11.6 months. One hundred patients received analgesics orally or transdermally, and 32 of these patients received oral controlled-release hydromorphone (Palladon® retard). The remaining patients received analgesic treatment with bisphosponates i.v. and non-medication measures. Four patients (n = 19) were treated with a transdermal system and 8 patients who received a diffe...","PeriodicalId":19808,"journal":{"name":"Pain Clinic","volume":"19 1","pages":"131-136"},"PeriodicalIF":0.0,"publicationDate":"2006-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75265320","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Clinical Evaluation of Pain 疼痛的临床评价
Pain Clinic Pub Date : 2006-04-01 DOI: 10.1163/156856906776760461
M. Zoppi, M. Maresca
{"title":"Clinical Evaluation of Pain","authors":"M. Zoppi, M. Maresca","doi":"10.1163/156856906776760461","DOIUrl":"https://doi.org/10.1163/156856906776760461","url":null,"abstract":"","PeriodicalId":19808,"journal":{"name":"Pain Clinic","volume":"319 1","pages":"105-107"},"PeriodicalIF":0.0,"publicationDate":"2006-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73561229","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Prevalence of pain among adults in Turkey 土耳其成年人疼痛的患病率
Pain Clinic Pub Date : 2006-04-01 DOI: 10.1163/156856906776760489
O. Hamzaoglu, Ozlem Ozkan, S. Erdine, Ecehan Balta, Mehmet Domac
{"title":"Prevalence of pain among adults in Turkey","authors":"O. Hamzaoglu, Ozlem Ozkan, S. Erdine, Ecehan Balta, Mehmet Domac","doi":"10.1163/156856906776760489","DOIUrl":"https://doi.org/10.1163/156856906776760489","url":null,"abstract":"Abstract Background: Epidemiological studies suggest that pain is an important public health problem. Aim: To determine prevalence of pain and the characteristics of pain symptoms. Method: A cross-sectional study was performed on the adult population in Turkey. This study was carried out in 15 cities selected from five demographic regions with a questionnaire consisting of 28 questions, and 2994 participants were interviewed with face-to-face interviews. Data were analyzed with chi-squared and Fisher exact tests. Results: The prevalence of pain among adults in Turkey was 63.7%. The prevalence increased with age and was higher in females, urban residents, in western and central regions than in males, rural residents and other demographic regions (p < 0.001). The most involved age was 55–65 years. The prevalence of pain in head, lower back, lower extremities and abdomen was 34.4%, 14.1%, 12.0% and 10.9%, respectively.","PeriodicalId":19808,"journal":{"name":"Pain Clinic","volume":"68 1","pages":"147-154"},"PeriodicalIF":0.0,"publicationDate":"2006-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89569354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 7
The role of nitric oxide on the analgesic effect of tramadol 一氧化氮对曲马多镇痛作用的影响
Pain Clinic Pub Date : 2006-04-01 DOI: 10.1163/156856906776760498
D. Karaaslan, T. Peker, T. Karaaslan, S. Özmen, F. Gultekin, Emin Şavik
{"title":"The role of nitric oxide on the analgesic effect of tramadol","authors":"D. Karaaslan, T. Peker, T. Karaaslan, S. Özmen, F. Gultekin, Emin Şavik","doi":"10.1163/156856906776760498","DOIUrl":"https://doi.org/10.1163/156856906776760498","url":null,"abstract":"Abstract Aims: The involvement of NO modulation in tramadol's mechanism of action is demonstrated indirectly by the alteration of the effect with the use of nitric oxide synthase inhibitor nitroG-L-arginine methyl ester (L-NAME). We aimed to investigate the alterations in serum and spinal cord NO levels following tramadol used alone or in combination with L-NAME or specific neuronal nitric oxide synthase (NOS) inhibitor 7-nitroindazole (7-NI), beside the changes in tail immersion reponses. Methods: Seventy-seven rats were randomly allocated into 7 groups. Group 1: sham group; Group 2: no drug; Group 3: tramadol 10 mg kg−1; Group 4: L-NAME 5 mg kg−1 + tramadol 10 mg kg−1; Group 5: L-NAME 10 mg kg−1 + tramadol 10 mg kg−1; Group 6: 7-NI 50 mg kg−1 + tramadol 10 mg kg−1; Group 7: 7-NI 100 mg kg−1 + tramadol 10 mg kg−1. Apart from Group 1, all the animals were exposed to a tail immersion test before medications (baseline) and 15 min after the tramadol injection. Following the tail-immersion test, a blood sampl...","PeriodicalId":19808,"journal":{"name":"Pain Clinic","volume":"6 1","pages":"123-130"},"PeriodicalIF":0.0,"publicationDate":"2006-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91331673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Does spinal anesthesia decrease the incidence of phantom pain 脊髓麻醉能降低幻肢痛的发生率吗
Pain Clinic Pub Date : 2006-04-01 DOI: 10.1163/156856906776760353
F. Uğur, Alive Esmaoglu, A. Akin, S. Ors, H. Aydoğan, N. Gulcu, A. Boyaci
{"title":"Does spinal anesthesia decrease the incidence of phantom pain","authors":"F. Uğur, Alive Esmaoglu, A. Akin, S. Ors, H. Aydoğan, N. Gulcu, A. Boyaci","doi":"10.1163/156856906776760353","DOIUrl":"https://doi.org/10.1163/156856906776760353","url":null,"abstract":"Abstract The objective of this retrospective study is to evaluate the effects of anesthesia type on phantom pain or sensation. A questionnaire of ten questions on phantom pain and sensation was sent by mail to patients who underwent lower extremity amputation surgery between 1996 and 2003 at Erciyes University Hospital. A total of 40 patients (age 51.0 ± 10.7 years, 80% male) who had general anesthesia and 27 patients (age 56.3 ± 14.0 years, 78% male) who had spinal anesthesia returned the questionnaire.Phantom pain incidences were defined as 33% in the spinal anesthesia group and 65% in the general anesthesia group and the difference was statistically significant. Phantom sensation incidences were 74% in the spinal anesthesia group and 77% in the general anesthesia group and the difference was not statistically significant. In conclusion, phantom pain incidence was lower in amputees treated with spinal anesthesia.","PeriodicalId":19808,"journal":{"name":"Pain Clinic","volume":"97 1","pages":"187-193"},"PeriodicalIF":0.0,"publicationDate":"2006-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85750835","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Comparison between effectiveness of intravenous patient-controlled analgesia and epidural analgesia in patients undergoing Cesarean section 剖宫产术患者静脉自控镇痛与硬膜外镇痛效果比较
Pain Clinic Pub Date : 2006-03-03 DOI: 10.1163/156856906775249758
Y. Chen, Kuan-Hung Chen, Chien-Hui Yang, A. Concejero, C.-H. Wang, Tsung Shing Lee, K. W. Cheng, C. Tseng, B. Jawan
{"title":"Comparison between effectiveness of intravenous patient-controlled analgesia and epidural analgesia in patients undergoing Cesarean section","authors":"Y. Chen, Kuan-Hung Chen, Chien-Hui Yang, A. Concejero, C.-H. Wang, Tsung Shing Lee, K. W. Cheng, C. Tseng, B. Jawan","doi":"10.1163/156856906775249758","DOIUrl":"https://doi.org/10.1163/156856906775249758","url":null,"abstract":"Abstract The aim of this study is to compare the effectiveness of epidural versus intravenous patient-controlled analgesia (PCA) during the post-cesarean section (CS) period. The anesthesia records and pain control charts of 90 patients undergoing CS from July 2003 to April 2004 were retrospectively analyzed. Twelve patients for emergency delivery and patients who refused to undergo regional anesthesia were grouped in Group I (GI); 78 patients received epidural anesthesia and were put in Group II (GII). Fourteen per cent of our patients received intravenous PCA following general anesthesia for CS. No differences in age, weight and Visual Analogue Scale (VAS) values on days 1–3 after intervention were observed between groups, but the total dose of morphine requirement to achieve adequate post-CS pain relief was significantly higher in GI than in GII.","PeriodicalId":19808,"journal":{"name":"Pain Clinic","volume":"39 1","pages":"31-35"},"PeriodicalIF":0.0,"publicationDate":"2006-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87828755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The effects of heat on osteoarthritis of the knee 热对膝关节骨关节炎的影响
Pain Clinic Pub Date : 2006-01-01 DOI: 10.1163/156856906775249802
K. Öneş, S. Tetik, C. Tetik, Nadir Öneş
{"title":"The effects of heat on osteoarthritis of the knee","authors":"K. Öneş, S. Tetik, C. Tetik, Nadir Öneş","doi":"10.1163/156856906775249802","DOIUrl":"https://doi.org/10.1163/156856906775249802","url":null,"abstract":"AbstractThe aim of our study was to evaluate the effects of the manual physical therapy methods conducted by superficial and deep heat treatments of primary bilateral knee osteoarthritis. A randomized, controlled trial was carried out. Eighty patients (160 knees) were included in the analysis. The patients were separated into two groups. Group I (n: 80 knees) performed daily physical therapy programs (ultrasounds, hot packs and exercises) in a period of fifteen days. Group II (n: 80 knees) performed only daily exercise programs in this period.Pain was evaluated by visual analogue scale (VAS) and WOMAC pain scale. Stiffness and functional capacity were measured by WOMAC osteoarthritis index at baseline, at the third and sixteenth weeks. At the third and sixteenth weeks, significant improvement in VAS, WOMAC were observed in both groups, when compared to baseline measures (Group I: p < 0.01, Group II: p < 0.05). At the sixteenth week, more significant improvement was observed in Group 1 than in Group II (p ...","PeriodicalId":19808,"journal":{"name":"Pain Clinic","volume":"20 1","pages":"67-75"},"PeriodicalIF":0.0,"publicationDate":"2006-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73736899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 10
Reliability and validity of a pain matching method of a pain induction apparatus 疼痛感应装置疼痛匹配方法的信度和效度
Pain Clinic Pub Date : 2006-01-01 DOI: 10.1163/156856906775249785
J. Lewis, D. Fishbain, Alesia Jones Parra Sipes, S. Asfour, B. Cole, R. Cutler, R. S. Rosomoff, H. Rosomoff
{"title":"Reliability and validity of a pain matching method of a pain induction apparatus","authors":"J. Lewis, D. Fishbain, Alesia Jones Parra Sipes, S. Asfour, B. Cole, R. Cutler, R. S. Rosomoff, H. Rosomoff","doi":"10.1163/156856906775249785","DOIUrl":"https://doi.org/10.1163/156856906775249785","url":null,"abstract":"Abstract Aims: Measuring clinical pain is hampered by few methods which properly compare values across patients. The purpose of this study is to describe a method to induce pain, assess pain threshold and tolerance, and determine a matching score for the visual analog scale. Method: An experimental apparatus was used to induce pain. Thirty-six healthy subjects and 10 patients participated. Healthy subjects and pain patients were assessed for strength, pain threshold, and pain tolerance on both hands, and the patients were measured on the matching score and the visual analog scale. Data were evaluated for internal consistency, test–retest reliability, and convergent validity. Results: The apparatus was internally consistent and reliable in provoking experimental pain. Validity was found between the visual analog scale and the matching pain score. Strength correlated with pain for healthy subjects, but not among patients. Conclusions: The apparatus was useful for inducing and studying experimental pain and ...","PeriodicalId":19808,"journal":{"name":"Pain Clinic","volume":"13 1","pages":"11-17"},"PeriodicalIF":0.0,"publicationDate":"2006-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90671366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Management of CRPS type II unresponsive to sympathetic nerve block with trigger points injection 触发点注射治疗交感神经阻滞无反应的CRPS II型
Pain Clinic Pub Date : 2006-01-01 DOI: 10.1163/156856906775249866
S. Yoon, H. Lee, H. Lim, S. Yoon, S. Chang
{"title":"Management of CRPS type II unresponsive to sympathetic nerve block with trigger points injection","authors":"S. Yoon, H. Lee, H. Lim, S. Yoon, S. Chang","doi":"10.1163/156856906775249866","DOIUrl":"https://doi.org/10.1163/156856906775249866","url":null,"abstract":"Abstract Objective: Complex regional pain syndromes (CRPS) type II (causalgia) is one of the causes of neuropathic pain. For the management of CRPS type II, various kinds of medications, nerve block, intravenous lidocaine and neurostimulation are used. We report good results by injection of trigger points around the left calf and lateral dorsum of the foot after unsuccessful different treatments in a patient with CRPS type II. Case Report: The authors describe a twenty-three year old female patient with CRPS type II after damage to the left sciatic and tibial nerves. The continuous epidural administration of opioids and local anesthetics, and oral medication with phenoxybenzamine did not sufficiently control the pain. Pain control was satisfactory with injections into the trigger points in the involved limb muscles. After six years, the patient complains of only slight tingling sensations around the left little toe.","PeriodicalId":19808,"journal":{"name":"Pain Clinic","volume":"17 1","pages":"99-102"},"PeriodicalIF":0.0,"publicationDate":"2006-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75446268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Fibromyalgia, obesity and obesity related measurements 纤维肌痛，肥胖和肥胖相关的测量
Pain Clinic Pub Date : 2006-01-01 DOI: 10.1163/156856906775249884
Hayal Güler, G. Sahin, Ismet As
{"title":"Fibromyalgia, obesity and obesity related measurements","authors":"Hayal Güler, G. Sahin, Ismet As","doi":"10.1163/156856906775249884","DOIUrl":"https://doi.org/10.1163/156856906775249884","url":null,"abstract":"Abstract Objective: To evaluate the relationship between obesity and fibromyalgia (FM). Methods: 241 female patients with FM were seen consecutively in outpatient clinic and they were analyzed. Spearman correlation was used. The relationship between FM and obesity was compared with respect to the BMI (body mass index) value. A p value of 0.05 was accepted as significant. Results: Body mass index was significantly correlated with age in FM patients. BMI was also correlated with waist/hip ratio. A significant positive correlation was found between health assessment questionnaire (HAQ) and VAS score in all patients. HAQ was also correlated positively with tender points (P 25 were considered as obese. Obese patients were older than non-obese patients. The values of waist/hip ratio and skin fold thickness and number of tender points were higher in obese patients. Also, the mean duration of disea...","PeriodicalId":19808,"journal":{"name":"Pain Clinic","volume":"44 1","pages":"25-29"},"PeriodicalIF":0.0,"publicationDate":"2006-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78663253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
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