Pamukkale Medical Journal最新文献

{"title":"Sağlık personellerinin kimyasal, biyolojik, radyasyon ve nükleer tehlikelerden korunma ve acil yardım uygulamaları ile ilgili bilgi düzeyleri ve farkındalıkları","authors":"Arzu Babacan","doi":"10.31362/patd.1315923","DOIUrl":"https://doi.org/10.31362/patd.1315923","url":null,"abstract":"Purpose: The accidental or intentional release of CBRN (Chemical, Biological, Radiological, Nuclear) substances into the environment causes significant loss of life and property and has adverse effects over a long time. This study was planned to raise awareness about protection from CBRN hazards and emergency aid practices, create CBRN awareness, and determine the knowledge level of healthcare professionals.\u0000Materials and methods: After reviewing the literature and regulations, the questionnaire was prepared based on the training module on \"Emergency Assistance in Chemical, Biological, Radiation and Nuclear Hazards\" for Emergency Health Services published by the Ministry of National Education; of the Republic of Turkey. The questionnaire was asked to participants before and after 10 hours of theoretical CBRN training, and the results were compared. \u0000Results: The participants were 58.4% female, 41.6% male, and the average age was 38. Most participants were doctors or nurses, and approximately three-quarters of the participants were emergency service staff. 35.6% of them had been working in the emergency department for 1-5 years. 61.4% had not received CBRN training, and 84.2% thought they needed sufficient knowledge and experience. 77.2% had not experienced any CBRN incident nor performed any intervention for CBRN. When the 22 questions asked about the level of CBRN knowledge were evaluated, it was seen that the correct answer rate was above 50% in seven questions of 22 and was above 50% in all questions in the post-test applied after the training. Their level of knowledge was found to be low before CBRN training and good after training.\u0000Conclusion: Theoretical training has a significant positive impact on creating CBRN awareness.","PeriodicalId":19789,"journal":{"name":"Pamukkale Medical Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87313456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Çocuklarda Akut Apandisitin Ameliyatsız Tedavisi","authors":"Osman Uzunlu, İncinur GENİŞOL ATAMAN","doi":"10.31362/patd.1334830","DOIUrl":"https://doi.org/10.31362/patd.1334830","url":null,"abstract":"Abstract \u0000Background: Most studies addressing non-operative management for acute appendicitis have focused on adults, and there are limited data available for children. We aimed to evaluate the results of successful non-operative management in children with acute uncomplicated appendicitis with our “additional criteria” and find which factors could be affecting the success rate and which cases could be candidates for non-operative management. \u0000Materials and methods: A total of 26 patients who were diagnosed with acute uncomplicated appendicitis and received non-operative management were re-evaluated retrospectively. Defining uncomplicated appendicitis was based on the duration of symptoms (","PeriodicalId":19789,"journal":{"name":"Pamukkale Medical Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73810476","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mikrobiyal keratitli hastaların demografik, laboratuvar ve klinik özelliklerinin analitik olarak incelenmesi","authors":"Fatma Sümer, İlkay Bahçeci̇, Süleyman Karaman, Feyza Uzun","doi":"10.31362/patd.1311349","DOIUrl":"https://doi.org/10.31362/patd.1311349","url":null,"abstract":"Purpose: In this study, we investigated epidemiological properties, clinical findings, risk factors, direct microscopy and culture results in the patients diagnosed with microbial keratitis. \u0000 \u0000Materials and Methods: We examined the hospital records of patients with microbial keratitis between March 2016 and March 2021, retrospectively. Also, clinical findings, risk factors, microbiological results, empirical treatment and treatment responses were evaluated. \u0000 \u0000Results:42 eyes of 42 patients whose mean age was 57.8 (range 18-70 years) included in the study. In 12 (28.5%) patients, a gram positive and gram negative bacterial finding was found in the stained microscopic examination. In total, microbial growth was detected in culture of 7 patients (16.6%), while growth was not detected in 35 patients (83.4%). No etiological factor was detected in 27 patients (64.4%). The complaints at admission were pain in 24 patients (57.6%), redness in 12 patients (28.8%), and both redness and pain in 6 patients (14.1%).While the visual acuity of 18 cases were preserved after the treatment, 24 cases (88.8%) achieved 1 or more line with the treatment. While the mean visual acuity was 0.69 ± 1.1 (0-3.1) logMAR before treatment, it increased to 0.79 ± 1.1 (0-3.1) logMAR after treatment (p=0.006). \u0000 \u0000Conclusion: The keratitis is a common cause of unilateral blindness. Early diagnosis and treatment of the keratitis is a significant role on the prognosis. The success of the therapy can be provided starting empirical antimicrobial therapy by taking into consideration of the regional risk factors and common pathogens.","PeriodicalId":19789,"journal":{"name":"Pamukkale Medical Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85350334","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Çocuk diş hekimliği kliniğine travmatik diş yaralanmaları nedeniyle başvuran hastaların değerlendirilmesi: retrospektif bir çalışma","authors":"Yıldırım Erdoğan, Arif Bolaca","doi":"10.31362/patd.1335765","DOIUrl":"https://doi.org/10.31362/patd.1335765","url":null,"abstract":"Purpose: The purpose of this study was to evaluate the prevalence of traumatic dental injuries (TDIs), as well as to evaluate different factors associated with TDIs among children and adolescents referred over three-year period to the Pamukkale University, Faculty of Dentistry, Department of Pediatric Dentistry, Denizli. \u0000Materials and methods: Dental trauma records of patients were reviewed regarding demographic data, affected teeth, type and etiology of TDIs, location and season of TDIs, time elapsed following TDIs and initial treatment, and treatment of TDIs. \u0000Results: Data associated with 258 patients, 471 traumatized teeth (primary teeth:152, permanent teeth:319) were analyzed. Both the primary and permanent maxillary central incisors were the most common affected teeth by TDIs. Primary teeth showed a higher frequency of periodontal tissue injuries (75.00%) and lower frequency of dental hard tissue injuries (21.05%) compared with permanent teeth (49.84% and 58.62%, respectively). Falls were the main etiological factor of TDIs both in the primary (73.68%) and permanent (58.31%) teeth. Only 27 patients (5.49%) were referred to the clinic within one hour following TDIs. \u0000Conclusion: Early management of TDIs is important to improve the prognosis of traumatized teeth and prevent post-traumatic complications. The low rate of early referral indicates the need for educational and preventive programs regarding TDIs among the patients, parents/legal guardians, and teachers.","PeriodicalId":19789,"journal":{"name":"Pamukkale Medical Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78213697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"HORMON RESEPTÖR POZİTİF, HER-2 NEGATİF METASTATİK MEME KANSERLİ HASTALARDA CDK4/6 İNHİBİTÖRÜ TEDAVİSİ ÖNCESİ SİSTEMİK İMMÜN İNFLAMASYON İNDEKSLERİNİN VE PROGNOSTİK NUTRİSYONEL İNDEKSİN PROGNOSTİK ÖNEMİ","authors":"Burçin ÇAKAN DEMİREL, Arzu Yaren, A. G. Demi̇ray, Burcu YAPAR TAŞKÖYLÜ, Tolga Doğan, Melek Özdemi̇r, Taliha GÜÇLÜ KANTAR, Canan Karan, Serkan Deği̇rmenci̇oğlu, Gamze GOKOZ DOGU","doi":"10.31362/patd.1268419","DOIUrl":"https://doi.org/10.31362/patd.1268419","url":null,"abstract":"Abstract \u0000Purpose: As systemic inflammatory indices and prognostic nutritional index are associated with poor prognosis in many tumor types, the goal of the present study was to ascertain their effect along with the neutrophil/lymphocyte ratio, platelet/lymphocyte ratio, lymphocyte/monocyte ratio, C-reactive protein/albumin ratio, and systemic inflammatory response index on the progression-free survival (PFS) and overall survival (OS) of hormone receptor-positive HER2-negative (HR+/HER2−) metastatic breast cancer patients before CDK4/6 inhibitor treatment. \u0000Materials and Method: The medical records of 79 patients with HR+/HER2− metastatic breast cancer who presented at the Medical Oncology Outpatient Clinic between January 2018 and May 2022 were retrospectively analyzed to gather relevant data measured before CDK4/6 inhibitor treatment in order to establish the effect of key markers on their PFS and OS. \u0000Results: The median age of the participating patients, 70 (88.6%) of whom were postmenopausal, was 53 years (range 26−80 years). While 68 patients (86.1%) had a 0 performance score, 10 (12.7%) developed metastases during adjuvant endocrine therapy. Factors affecting PFS were age","PeriodicalId":19789,"journal":{"name":"Pamukkale Medical Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91275936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acil serviste KOAH atağı başvuruları ile hava kirliliği ve sıcaklık arasındaki ilişki","authors":"Hülya YILMAZ BAŞER, Hale Nur Can","doi":"10.31362/patd.1320033","DOIUrl":"https://doi.org/10.31362/patd.1320033","url":null,"abstract":"Purpose: We aimed to investigate the relationship between air pollution, temperature and COPD attacks in two different centers. \u0000Materials and methods: Two centers, Bandırma and Van, were included in the study. In addition, temperature grouping was also done. Air pollution and temperature values were obtained from official sites. COPD data were scanned retrospectively from hospital information management systems. \u0000Results: In the first 3 months (Group 1) included in the study, the PM10 value, the number of COPD treatment in the emergency department (ED) and the number of COPD hospitalizations in the ED were also found to be high in Van (p=0.05, p=0.05 and p=0.034, respectively). In the last 3 months (Group 2) period included in the study, it was observed that the mean temperature was lower in Van, and the rate of hospitalizations and hospitalizations due to COPD were higher in Van (p=0.05, p=0.05, and p=0.05, respectively). In the correlation analysis, a strong positive correlation was found between PM10 value and COPD treatment and hospitalization for COPD in Group 1 (r;0.986, p","PeriodicalId":19789,"journal":{"name":"Pamukkale Medical Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82675269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"MGUS'ta azalmış GADD45A gen ifadesi seviyesi","authors":"Ilknur Suer, Aynur DAĞLAR ADAY, Gözde Öztan","doi":"10.31362/patd.1291199","DOIUrl":"https://doi.org/10.31362/patd.1291199","url":null,"abstract":"Purpose: Monoclonal gammopathy of undetermined significance (MGUS) is a plasma cell dyscrasia. It is known that MGUS has an increased risk of progression to multiple myeloma (MM), and also prepares the ground for diseases such as Waldenstrom macroglobulinemia (WM), non-Hodgkin lymphoma, and chronic lymphocytic leukemia (CLL). Our study aimed to evaluate whether some important p53 pathway genes differ in terms of expression in MGUS and healthy individuals. Materials and methods: For the study, bone marrow was collected from 8 healthy individuals and 8 individuals diagnosed with MGUS, and RNA samples were isolated. Expression levels of various genes involved in the p53 pathway were compared using the RT2-profiler PCR array. β-actin housekeeping gene expression level was used for normalization. The Pearson Correlation analysis and Receiver Operating Characteristic (ROC) analysis were conducted. Results: Among the genes whose expression levels were examined in this study, it was determined that the expression level of only the GADD45A gene decreased significantly in MGUS compared to the control group (p=0.027). Pearson correlation data showed that GADD45A gene expression was highly correlated with 12 of the other genes (APAF1, CDK4, PCNA, BAX, CDKN2A, CASP9, CHECK2, MDM2, RB1, P53, BCL2, CHEK1) examined in the p53 pathway (r>0.7). In addition, according to the ROC analysis, GADD45A is detected to have a strong discrimination power between MGUS and healthy individuals (AUC=0.797 and p=0.015). Conclusion: The decreased expression of the GADD45A gene in the MGUS group compared to the control group may be useful as a new biomarker to detect the risk of progression from MGUS to MM.","PeriodicalId":19789,"journal":{"name":"Pamukkale Medical Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81281082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"COVID-19 pandemisinin ulusal göz hastalıkları toplantılarındaki bildiri katılımı üzerine etkileri","authors":"İ. Toprak, D. Kilic","doi":"10.31362/patd.1332438","DOIUrl":"https://doi.org/10.31362/patd.1332438","url":null,"abstract":"Purpose: The aim of the current study is to evaluate the effect of COVID-19 pandemic on paper participation in national ophthalmology meetings held by the Turkish Ophthalmology Association (TOA). \u0000Materials and methods: The data for the previous national ophthalmology meetings held by the TOA were gathered retrospectively from the TOA website. The COVID-19 pandemic-related online sessions and meetings with a scheduled in-person follow-up were taken into consideration. The number of poster and oral presentations and subject areas of the papers were recorded. \u0000Results: The total number of poster and oral presentations in online meetings was 1505, while it was 1294 in face-to-face meetings (a 14.0% difference). Regarding poster presentations, a total of 1001 posters were presented in online meetings, whereas number of poster presentations was 865 in face-to-face meetings. Similarly, in online meetings, the number of oral presentations was 504, while it was 429 in face-to-face meetings. This finding demonstrated both poster and oral presentation participation was higher by 13.5% and 14.8% (respectively) in online meetings than in the face-to-face meetings. \u0000Conclusion: It appears that national ophthalmology meetings held online during the COVID-19 pandemic had a favorable impact on the paper submission rate, and online meetings made sure that scientific sharing and collaboration continued and made it accessible to wider populations.","PeriodicalId":19789,"journal":{"name":"Pamukkale Medical Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82796471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tıp Fakültesi Öğrencilerinde Sosyal Medya Bağımlılığının; Dissosiyasyon, Sosyal Anksiyete ve Aleksitimi ile İlişkisi","authors":"Merve AKTAŞ TERZİOĞLU, Tuğçe TOKER UĞURLU","doi":"10.31362/patd.1321281","DOIUrl":"https://doi.org/10.31362/patd.1321281","url":null,"abstract":"Objective: The aim of this study was to evaluate social media addiction in medical faculty students and the relationships with dissociation and social anxiety experienced in social media use and the level of alexithymia. \u0000Methods: 329 students who agreed to participate in the research completed the following scales; Bergen Social Media Addiction Scale (BSMAS), Toronto Alexithymia Scale (TAS-20), Van Online Dissociative Experiences Scale (VODES), Social Anxiety Scale for Social Media Users (SAS-SMU). \u0000Results: The 4 sub-scales of the SAS-SMU, the 3 sub-scales of the TAS, and the VODES were analyzed as independent variables and the BSMAS was evaluated as a dependent variable. According to this, social media addiction was affected by the shared content anxiety and self-assessment anxiety sub-scale points of the SAS-SMU, and by the VODES points. Shared content anxiety was determined to predict social media addiction positively and significantly (β=0.264, t (320) = 3.16, p=0.002). Self-assessment anxiety was determined to predict social media addiction positively and significantly (β=0.169, t (320) = 2.23, p=0.026). Online dissociative experiences was determined to predict social media addiction positively and significantly (β=0.217, t (320) = 4.15, p","PeriodicalId":19789,"journal":{"name":"Pamukkale Medical Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79089969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of the effectiveness of various valsalva maneuvers in the management of stable narrow and wide QRS complex tachycardia in the emergency department","authors":"Reşad Beyoğlu, Mert Özen","doi":"10.31362/patd.1312891","DOIUrl":"https://doi.org/10.31362/patd.1312891","url":null,"abstract":"Purpose: Narrow and wide QRS complex tachycardias are among the causes of arrhythmia in patients frequently admitted to the emergency department (ED). The first recommended step in the management of patients with a stable narrow and wide QRS tachycardia is a vagal maneuver. Althougah there are many maneuvers that can provide vagal stimulation, the most effective vagal maneuver is still unknown. This study aims at determining the most effective vagal maneuver by comparing the four most commonly used maneuvers. \u0000Materials and methods: One hundred and thirty-two patients were included in this study; they were randomly and equally distributed into four groups. Carotid sinus massage (CSM) was applied to the first group, the REVERT method was applied to the second group (a 10-cc injector was used), a modified REVERT method was applied to the third group (a 60-cc injector was used), and the abeslang (wooden tongue depressor) method was applied to the fourth group. During these four applications, the patients’ vital signs were monitored, and preparations were made for any emergency. \u0000Results: Of the 132 patients included in the study, 61 (46.2%) were males, and 71 (53.8%) were females. The average age of the patients was 56.3 years. One hundred and twenty-six had narrow QRS tachycardias, and 6 had stable wide QRS tachycardias. The patients were randomly distributed into 4 groups. In the 1st group, 1 patient (3%) returned to a normal rhythm with the CSM method. In the 2nd group, 3 patients (9.1%) returned to a normal rhythm with the REVERT method. Nine patients (27.3%) in the 3rd group returned to a normal rhythm with the modified REVERT method. 6 patients (18.2%) in the 4th group returned to normal rhythm with the abeslang method. None of the stable wide QRS tachycardias responded to vagal stimulation methods. \u0000Conclusion: The modified REVERT and abeslang methods are preferred primarily in patients entering the ED with the complaint of a stable narrow or wide QRS tachycardia in the case that a vagal maneuver is to be applied. On the other hand, a vagal maneuver is not effective in the management of a stable wide QRS tachycardia.","PeriodicalId":19789,"journal":{"name":"Pamukkale Medical Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74659901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}