Pain MedicinePub Date : 2024-12-28DOI: 10.1093/pm/pnae132
Marcelo França Moreira, Marco Aurelio Pinho Oliveira
{"title":"Exploring the Interplay Between Catastrophizing and Endometriosis Pain Through Two-Wave and Intensive Longitudinal Data.","authors":"Marcelo França Moreira, Marco Aurelio Pinho Oliveira","doi":"10.1093/pm/pnae132","DOIUrl":"https://doi.org/10.1093/pm/pnae132","url":null,"abstract":"<p><strong>Background: </strong>Endometriosis, characterized by the presence of endometrial-like tissue outside the uterus, results in chronic pelvic pain. However, lesion characteristics alone cannot fully explain the complexity of endometriosis-related pain. Pain catastrophizing, a cognitive process that influences pain perception, has traditionally been studied through cross-sectional or two-wave designs, which struggle to capture its dynamic interplay with endometriosis pain. To address these gaps, our study explores the bidirectional relationship between pain catastrophizing and pain outcomes-including intensity, frequency, and flares-over a detailed four-week period, an aggregated 30-day timeframe, and across sensory and affective dimensions.</p><p><strong>Methods: </strong>A Latent Growth Curve Model assessed the relationship between pain catastrophizing, initial pain levels, and endometriosis pain trajectories over four weeks. Additionally, four mediator models explored how baseline pain catastrophizing affects various pain aspects, including sensory and affective dimensions, and its subsequent influence on pain catastrophizing.</p><p><strong>Results: </strong>Results indicate that high levels of pain catastrophizing significantly escalate endometriosis pain over four weeks, affecting average pain intensity, episode frequency, and flares over 30 days. Pain catastrophizing also adversely impacts sensory and affective dimensions. These elements partially mediate baseline pain catastrophizing's effect on week five levels, revealing a bidirectional relationship. Notably, while the affective dimension amplifies subsequent pain catastrophizing, the sensory dimension exerts a contrasting negative influence.</p><p><strong>Conclusion: </strong>The study highlights the bidirectional influence between pain catastrophizing and several aspects of endometriosis-related pain. Sensory and affective dimensions play distinct roles, with implications for personalized interventions. Limitations and clinical relevance are discussed.</p>","PeriodicalId":19744,"journal":{"name":"Pain Medicine","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2024-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142896496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pain MedicinePub Date : 2024-12-26DOI: 10.1093/pm/pnae131
Dakota W Cintron, Anthony D Ong, M Carrington Reid
{"title":"What Makes Life Go Well? A Network Topic Modeling Analysis of Well-Being Practices in Adults with Chronic Pain.","authors":"Dakota W Cintron, Anthony D Ong, M Carrington Reid","doi":"10.1093/pm/pnae131","DOIUrl":"https://doi.org/10.1093/pm/pnae131","url":null,"abstract":"<p><strong>Objective: </strong>This study leverages natural language processing techniques to identify specific practices older adults with chronic pain adopt to enhance well-being.</p><p><strong>Method: </strong>We applied network topic modeling to open-ended survey responses from 683 adults (57% female) who reported experiencing chronic pain in the Midlife in the United States (MIDUS) study, analyzing responses to the question \"What do you do to make your life go well?\" Structural equation modeling was used to examine the relationships between identified topics and measures of pain interference and prescription pain medication use, adjusting for sociodemographics and well-being indicators.</p><p><strong>Results: </strong>The analyses revealed twelve key topics, including avoiding stress, maintaining social connections, and practicing spirituality and faith. Notably, maintaining social connections was negatively associated with pain interference (β = -0.14, SE = 0.05, p < 0.05) and prescription pain medication use (β = -0.11, SE = 0.04, p < 0.05).</p><p><strong>Conclusion: </strong>The findings demonstrate the utility of network topic modeling in identifying complex psychosocial dimensions influencing chronic pain management, providing insights into the distinct role of well-being practices in shaping pain outcomes.</p>","PeriodicalId":19744,"journal":{"name":"Pain Medicine","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2024-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142896499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Enhancing Early Career Development in Pain Medicine: The comprehensive Role of Mentorship.","authors":"Yashar Eshraghi, Meredith Barad, Scott Pritzlaff, Trent Emerick, Sayed Wahezi, Magdalena Anitescu, Lynn Kohan","doi":"10.1093/pm/pnae128","DOIUrl":"https://doi.org/10.1093/pm/pnae128","url":null,"abstract":"","PeriodicalId":19744,"journal":{"name":"Pain Medicine","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2024-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142847293","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pain MedicinePub Date : 2024-12-14DOI: 10.1093/pm/pnae129
Abby Pei-Ting Chiu, G A Nagana Gowda, Wentao Zhu, Lars Arendt-Nielsen, Daniel Raftery, Michele Curatolo
{"title":"Cerebrospinal Fluid Metabolomics of Pain in Patients with Spinal Muscle Atrophy.","authors":"Abby Pei-Ting Chiu, G A Nagana Gowda, Wentao Zhu, Lars Arendt-Nielsen, Daniel Raftery, Michele Curatolo","doi":"10.1093/pm/pnae129","DOIUrl":"https://doi.org/10.1093/pm/pnae129","url":null,"abstract":"","PeriodicalId":19744,"journal":{"name":"Pain Medicine","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2024-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142824326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pain MedicinePub Date : 2024-12-12DOI: 10.1093/pm/pnae126
Debbie J Bean, Natalie L Tuck, Nico Magni, Tipu Aamir, Catherine Pollard MHlthPrac, Gwyn N Lewis
{"title":"The efficacy of an interdisciplinary pain management program for complex regional pain syndrome compared to low back pain and chronic widespread pain: An observational study.","authors":"Debbie J Bean, Natalie L Tuck, Nico Magni, Tipu Aamir, Catherine Pollard MHlthPrac, Gwyn N Lewis","doi":"10.1093/pm/pnae126","DOIUrl":"https://doi.org/10.1093/pm/pnae126","url":null,"abstract":"<p><strong>Background: </strong>Little research has assessed the efficacy of interdisciplinary pain management programs (IPMPs) for complex regional pain syndrome (CRPS), whereas evidence shows that IPMPs are effective for low back pain (LBP) and chronic widespread pain (CWP). This study aimed to determine whether outcomes following an IPMP differ for people with CRPS compared to LBP and CWP. In addition, we determined whether it is possible to predict IPMP outcomes using baseline characteristics.</p><p><strong>Methods: </strong>People with CRPS (N = 66) who had completed a 3-week IPMP were compared with age- and gender- matched controls with LBP (N = 66) and CWP (N = 66). Measures of pain intensity, pain interference and psychological factors were extracted for pre- and post-program, and at 1, 6 and 12 months. Latent class analysis identified recovery trajectories for pain intensity and pain interference. Chi-square analyses assessed differences between diagnostic groups in recovery trajectories. Machine learning models were implemented to predict recovery trajectories from baseline scores.</p><p><strong>Results: </strong>Two recovery trajectories for each dependent variable (pain interference and for pain intensity) were identified: good responders and poorer responders. Following IPMPs, 37% of people belonged to a good responder recovery trajectory for pain interference, and 11% belonged to a good responder recovery trajectory for pain intensity. Recovery trajectories were equal across the three diagnostic groups (CRPS, LBP, CWP) for pain interference (χ2=1.8, p=0.4) and intensity (χ = 0.2, p=0.9). Modelling to predict outcomes correctly classified 69% of cases for pain interference and 88% of cases for pain intensity recovery trajectories using baseline scores.</p><p><strong>Conclusion: </strong>People with CRPS, LBP, and CWP experience similar benefits following an IPMP. This supports the use of IPMPs for people with CRPS.</p>","PeriodicalId":19744,"journal":{"name":"Pain Medicine","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2024-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142818803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pain MedicinePub Date : 2024-12-12DOI: 10.1093/pm/pnae125
Changho Yi, Evgeny Bulat, Oranicha Jumreornvong, Sravya Madabhushi, Sudhir Diwan, Alan David Kaye, Reda Tolba, Erkan Kurt, Michael E Schatman, R Jason Yong, Christopher L Robinson, Jamal Hasoon
{"title":"Peripheral Nerve Stimulation for Post-Spinal Fusion Sacroiliac Joint Pain.","authors":"Changho Yi, Evgeny Bulat, Oranicha Jumreornvong, Sravya Madabhushi, Sudhir Diwan, Alan David Kaye, Reda Tolba, Erkan Kurt, Michael E Schatman, R Jason Yong, Christopher L Robinson, Jamal Hasoon","doi":"10.1093/pm/pnae125","DOIUrl":"https://doi.org/10.1093/pm/pnae125","url":null,"abstract":"","PeriodicalId":19744,"journal":{"name":"Pain Medicine","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2024-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142818802","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pain MedicinePub Date : 2024-12-10DOI: 10.1093/pm/pnae124
Christopher L Robinson, Pawan K Solanki, Sean Snyder, Adam Amir, Antje Barreveld, Rory Vu Mather, Ivo H Cerda, Michael Motoc, Harman Chopra, R Jason Yong, Joel Castellanos, Timothy Furnish, Alan D Kaye, Vwaire Orhurhu, Trent Emerick
{"title":"Chronic Pain Education: Past, Present, and Future of Psychedelics for the Management of Chronic Pain.","authors":"Christopher L Robinson, Pawan K Solanki, Sean Snyder, Adam Amir, Antje Barreveld, Rory Vu Mather, Ivo H Cerda, Michael Motoc, Harman Chopra, R Jason Yong, Joel Castellanos, Timothy Furnish, Alan D Kaye, Vwaire Orhurhu, Trent Emerick","doi":"10.1093/pm/pnae124","DOIUrl":"https://doi.org/10.1093/pm/pnae124","url":null,"abstract":"","PeriodicalId":19744,"journal":{"name":"Pain Medicine","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2024-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142807561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pain MedicinePub Date : 2024-11-26DOI: 10.1093/pm/pnae122
Pradeep Suri, Yakov A Tsepilov, Elizaveta E Elgaeva, Frances M K Williams, Maxim B Freidin, Ian B Stanaway
{"title":"A Mendelian randomization study finds no evidence for causal effects of C-reactive protein (CRP) on chronic pain conditions.","authors":"Pradeep Suri, Yakov A Tsepilov, Elizaveta E Elgaeva, Frances M K Williams, Maxim B Freidin, Ian B Stanaway","doi":"10.1093/pm/pnae122","DOIUrl":"10.1093/pm/pnae122","url":null,"abstract":"<p><p>This two-sample Mendelian randomization study examined causal associations of C-reactive protein (CRP) with spinal pain, the extent of multisite chronic pain, and chronic widespread musculoskeletal pain. No causal associations were found between CRP and these pain conditions.</p>","PeriodicalId":19744,"journal":{"name":"Pain Medicine","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2024-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142731396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pain MedicinePub Date : 2024-11-26DOI: 10.1093/pm/pnae123
Chris Pierson, Richard Wilson, Karen Brewer-Mixon, Yi-Ting Tzen, Jon Williamson, Kristine Hansen, Terri Hisel, Nitin Jain
{"title":"Pressure Pain Sensitivity is Independent of Structural Pathology in Patients with Subacromial Pain Syndrome: A Cross-Sectional Analysis.","authors":"Chris Pierson, Richard Wilson, Karen Brewer-Mixon, Yi-Ting Tzen, Jon Williamson, Kristine Hansen, Terri Hisel, Nitin Jain","doi":"10.1093/pm/pnae123","DOIUrl":"https://doi.org/10.1093/pm/pnae123","url":null,"abstract":"<p><strong>Objective: </strong>To compare localized (primary) and widespread (secondary) hyperalgesia using pressure pain threshold (PPT) of patients with normal imaging findings, rotator cuff tear, or other pathologies.</p><p><strong>Design: </strong>This was a cross-sectional design with data collected at a single time point.</p><p><strong>Setting: </strong>This study was performed at two large, urban, academic medical centers.</p><p><strong>Subjects: </strong>Participants included had chronic subacromial pain syndrome for three months or longer. Each participant was categorized into one of three imaging groups: normal imaging, rotator cuff tear, or other structural pathology.</p><p><strong>Methods: </strong>Primary hyperalgesia was assessed with PPT at the midsection of the painful shoulder's lateral deltoid. Secondary hyperalgesia was assessed with PPT at the contralateral tibialis anterior muscle (TA). An ANOVA and ANCOVA was performed for each objective. ANCOVA covariates included age, sex, education level, and pain duration.</p><p><strong>Results: </strong>The 103 participants included 55 males, had a median age of 55 years, median pain duration of 14.0 months, and a median composite Shoulder Pain and Disability Index (SPADI) score of 43.1%. The ANCOVA for primary hyperalgesia showed no significant difference in square-root adjusted deltoid PPT between imaging groups (F = 1.04, p = 0.3589). The ANCOVA for secondary hyperalgesia showed no significant difference in log-adjusted TA PPT between imaging groups (F = 0.24, p = 0.7900).</p><p><strong>Conclusions: </strong>No significant difference was observed in the analysis of ipsilateral deltoid or contralateral TA PPT between patients with differing structural shoulder pathologies. These findings suggest that the three types of structural shoulder abnormalities we examined are not significantly associated with differences in one measure of hyperalgesia.</p>","PeriodicalId":19744,"journal":{"name":"Pain Medicine","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2024-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142731397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}