A. Olowo-Okere, Y. Ibrahim, B. Olayinka, J. Ehinmidu
{"title":"Epidemiology of surgical site infections in Nigeria: A systematic review and meta-analysis","authors":"A. Olowo-Okere, Y. Ibrahim, B. Olayinka, J. Ehinmidu","doi":"10.4103/npmj.npmj_72_19","DOIUrl":"https://doi.org/10.4103/npmj.npmj_72_19","url":null,"abstract":"Introduction: Surgical site infection (SSI) is a major patient safety concern in hospitals. Unlike most developed countries, Nigeria does not yet have an established national system to monitor the occurrence of this infection. This meta-analysis was thus designed to determine the pooled cumulative incidence of SSIs and various determinants of its occurrence in Nigeria. Methods: The electronic databases were systematically searched for articles reporting the occurrence and risk factors associated with SSIs in Nigeria from January 2000 to December 2018. The eligible articles were evaluated using a set of pre-defined criteria. The extracted data were analysed using the comprehensive meta-analysis software. The Begg and Egger's regression tests were used to assess the risk of bias of the included publications. Results: Thirty-two articles emanating from the six geopolitical regions of Nigeria were included in this meta-analysis. The pooled cumulative incidence of SSIs was 14.5% (95% confidence interval [CI]: 0.113–0.184) with the highest incidence reported in the north-eastern region (27.3%, 95% CI: 0.132–0.481) of the country. It was also found to occur more predominantly following colorectal and abdominal surgeries, among elderly patients and in patients with co-morbid conditions. The most frequently reported was the superficial incisional SSIs occurring in 62.5% (95% CI: 0.333–0.848). Higher preponderance was also observed among patients with dirty wounds (52.7%, 95% CI: 0.367–0.682). Conclusion: This meta-analysis documents for the first time the national burden of SSIs in Nigeria. Control measures geared towards its reduction should be strengthened and a national policy on SSI surveillance, prevention and control developed.","PeriodicalId":19720,"journal":{"name":"Nigerian Postgraduate Medical Journal","volume":"26 1","pages":"143 - 151"},"PeriodicalIF":1.1,"publicationDate":"2019-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43669702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Abstracts of papers presented at the 12th annual scientific conference of the national postgraduate medical college of Nigeria, Kano 2017","authors":"","doi":"10.4103/npmj.npmj_194_17","DOIUrl":"https://doi.org/10.4103/npmj.npmj_194_17","url":null,"abstract":"","PeriodicalId":19720,"journal":{"name":"Nigerian Postgraduate Medical Journal","volume":"24 1","pages":"257 - 275"},"PeriodicalIF":1.1,"publicationDate":"2017-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48868552","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Chizara C Okeke, K. Ailoje-Ibru, K. Olukoya, Rose O Ogbeche, Abiola J Adewusi, Ebele C. Iloabachie, O. Ashiru
{"title":"Successful pregnancy outcome after in vitro fertilisation following Pre-implantation Genetic Diagnosis/Polymerase Chain Reaction screening for single gene disorder (sickle cell anaemia) before embryo transfer: ...","authors":"Chizara C Okeke, K. Ailoje-Ibru, K. Olukoya, Rose O Ogbeche, Abiola J Adewusi, Ebele C. Iloabachie, O. Ashiru","doi":"10.4314/NMJ.V55I1","DOIUrl":"https://doi.org/10.4314/NMJ.V55I1","url":null,"abstract":"A couple, both carriers of the sickle cell anaemia trait (Genotype HbAS) with an offspring already affected with the genetic disease underwent a Pre-implantation Genetic Diagnosis/ Polymerase Chain Reaction screening of biopsied blastomeres. DNA analysis of single blastomeres was carried out to find out indicated a viable intra-uterine pregnancy with embryos which carried the sickle cell mutation, which resulted in a livebirth (HbAS). PGD/PCR in combination with IVF appears to be the most suitable treatment plan for patients who are at a higher risk of reproducing offspring affected with inheritable genetic diseases. Keywords : PGD/PCR, Sickle cell anaemia, IVF, Biopsy, FET","PeriodicalId":19720,"journal":{"name":"Nigerian Postgraduate Medical Journal","volume":"30 1","pages":"87-90"},"PeriodicalIF":1.1,"publicationDate":"2014-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78750366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ig Achinge, A. Malu, E. Okeke, E. Agaba, M. Misauno
{"title":"Prevalence of Oesophageal Varices in Newly Diagnosed Chronic Liver Disease Patients at The Jos University Teaching Hospital, Jos","authors":"Ig Achinge, A. Malu, E. Okeke, E. Agaba, M. Misauno","doi":"10.4314/nmj.v52i2","DOIUrl":"https://doi.org/10.4314/nmj.v52i2","url":null,"abstract":"Background : Variceal bleeding is an important complication of portal hypertension and a major cause of death in patients with chronic liver disease (CLD) world wide. This study was carried out to document the occurrence of oesophageal varices and its clinical correlates among 80 Nigerian patients with CLD. Patients and Methods: Eighty patients with CLD were stratified into three groups based on Child- Turcotte- pugh's classification for severity of CLD in a one year study. They had upper gastrointestinal endoscopy to detect and characterize varices. Results : Sixty (75%) of the patients had oesophageal varices at endoscopy with 88.3% having grade 2 or 3 varices while 73.3% had moderate/large varices. Thirty five percent of the varices had “red signs” with “red whale” markings as the predominant red sign. Gastric varices were seen in 12.5%. Variceal size was significantly associated with severity of liver disease (P<0.05) as 90% of the patients with varices presented with Child's class B or C. A multiple logistic regression analysis identified advancing age, ascites, shrunken liver span and low platelet count as independent predictors of oesophageal varices. Conclusion : A large proportion of Nigerian CLD patients have advanced at-risk-for-bleeding oesophageal varices at diagnosis. Early diagnosis of CLD in Nigerians is warranted. Key words : Prevalence, Oesophageal varices, Chronic liver disease, Cirrhosis","PeriodicalId":19720,"journal":{"name":"Nigerian Postgraduate Medical Journal","volume":"11 1","pages":"128-132"},"PeriodicalIF":1.1,"publicationDate":"2011-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73129499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
O. Ejiofor, G. Emechebe, W. Igwe, C. Ifeadike, Chika F. Ubajaka
{"title":"Hepatitis C virus infection in Nigerians","authors":"O. Ejiofor, G. Emechebe, W. Igwe, C. Ifeadike, Chika F. Ubajaka","doi":"10.4314/NMJ.V51I4.62482","DOIUrl":"https://doi.org/10.4314/NMJ.V51I4.62482","url":null,"abstract":"Background:Hepatitis C virus is a chronic lifelong infection in the majority of patients who are infected with the virus. Not much is known and written/published about this virus in Nigeria. Objective: To assess the status of hepatitis C virus infection in Nigeria. Materials and method:Sources of information were mainly from published works in and outside Nigeria. The information was extracted over a period of 12 months from January to December 2009. Results:So far the prevalence of hepatitis C. virus infection is increasing in Nigeria, ranging from 4.7-5% in Ilorin, to 5.3-6.6% in Enugu, to 11% in Ibadan and 20% in Benin. Children and adults are all at risk of being infected especially sickle cell disease patients. Others include those who are exposed to the common risk factors like Blood transfusion, haemodialyisis, recycling of syringes and needles, sexual promiscuity. Conclusion:Reduction in the Hepatitis C virus infection could be achieved by Health education campaign of the general public and by support from government and non-governmental organizations for the to provision of antiviral and immunostimulatory drugs free of charge for those already infected.","PeriodicalId":19720,"journal":{"name":"Nigerian Postgraduate Medical Journal","volume":"18 1","pages":"173-176"},"PeriodicalIF":1.1,"publicationDate":"2010-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87786851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Spontaneous rupture of gravid horn of bicornuate uterus at term - A case report","authors":"B. Nwosu, J. Ugboaja, A. Obi-Nwosu","doi":"10.4314/NMJ.V51I4.62494","DOIUrl":"https://doi.org/10.4314/NMJ.V51I4.62494","url":null,"abstract":"Uterine structural abnormalities are known causes of recurrent pregnancy losses occurring especially within the second trimester. However, recent reports show that the rate of pregnancy losses caused by uterine anomalies may not be as high as previously feared. We report a case of a 28 year old secondigravida with uterus bicornis unicollis who had spontaneous rupture of one of the uteri in pregnancy, had excision of one horn of the double uterus and was able to carry a subsequent pregnancy to term and achieve a live birth. The literature on double uterus was also reviewed.","PeriodicalId":19720,"journal":{"name":"Nigerian Postgraduate Medical Journal","volume":"171 1","pages":"184-185"},"PeriodicalIF":1.1,"publicationDate":"2010-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77822747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The role of general dental practitioner in oral health","authors":"A. L. Nwoku","doi":"10.4314/NMJ.V51I3.59900","DOIUrl":"https://doi.org/10.4314/NMJ.V51I3.59900","url":null,"abstract":"Although it is widely acclaimed in the recent past that the Nigerian has healthy set of teeth and no oral health problems. Our findings show that over 2.3 million Nigerians between the ages of 3 and 70 years attend dental clinics yearly for treatment. In spite of this, provision of oral health care and services at the local outage is highly deficient. Just as the eyes may be the window to the soul, the mouth is a window to the body's health. The state of oral health can offer lots of clues about the overall health as these are more closely connected than one might realize. Oral Health is connected to many health conditions beyond the mouth, and indeed, sometimes the first sign of a disease may show up in the mouth. The mouth is normally teeming with bacteria, and some researchers believe that these bacteria and inflammation from the mouth are linked to other health problems including heart disease. Other diseases that affect the oral cavity include, but not limited to caries, infections of the gum and jaws, malformations, benign and malignant tumours, as well as diabetes. The general dental practitioner therefore has very important duties. These include early recognition and diagnosis of oral health problems, oral health promotion, education and provision of care and services. Dental professionals should make dental patients aware that oral health care can't wait. They should market their practice to increase business and oral health care awareness.","PeriodicalId":19720,"journal":{"name":"Nigerian Postgraduate Medical Journal","volume":"11 1","pages":"125"},"PeriodicalIF":1.1,"publicationDate":"2010-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74610880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
B. Uzochukwu, Ogochukwu P Ezeoke, U. Emma-Ukaegbu, O. Onwujekwe, F. T. Sibeudu
{"title":"Malaria Treatment Services in Nigeria: A Review","authors":"B. Uzochukwu, Ogochukwu P Ezeoke, U. Emma-Ukaegbu, O. Onwujekwe, F. T. Sibeudu","doi":"10.4314/NMJ.V51I3.59898","DOIUrl":"https://doi.org/10.4314/NMJ.V51I3.59898","url":null,"abstract":"Malaria remains a major Public Health problem in Nigeria and causes death and illness in children and adults, especially pregnant women. Malaria case management remains a vital component of the malaria control strategies. This entails early diagnosis and prompt treatment with effective antimalarial medicines. The objectives of this review is to enable health professionals to understand the magnitude of malaria treatment services in Nigeria, to improve knowledge for rational malaria management within different health system contexts with a view to improving access to malaria treatment. The review therefore looks at the following areas: clinical disease and epidemiology; the burden of malaria in Nigeria; objectives of treatment; antimalarial treatment policy; malaria diagnosis, treatment strategies/ National responses; treatment sources. The review concludes that for improved malaria treatment services in Nigeria, there is an urgent need to develop adequate strategies that will ensure better access to medicines by getting evidence-based and effective medicines to the people who need them, whether by reducing their costs, promoting equity in access, improving their distribution, increasing their efficacy and acceptability, or slowing down the development of antimicrobial resistance.","PeriodicalId":19720,"journal":{"name":"Nigerian Postgraduate Medical Journal","volume":"37 1","pages":"114"},"PeriodicalIF":1.1,"publicationDate":"2010-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73246651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Improving Low Awareness and Inadequate Access to Oral Health Care in Nigeria: The Role of Dentists, the Government & Non- Governmental Agencies.","authors":"A. Olusile","doi":"10.4314/NMJ.V51I3.59905","DOIUrl":"https://doi.org/10.4314/NMJ.V51I3.59905","url":null,"abstract":"In Nigeria presently, dentistry and oral health issues are not receiving priority attention. There is a general low awareness and inadequate access to oral health care in Nigeria, consequently, the oral health of the populace is getting worse and the morbidity is high. For a broad-based approach to the problems of oral health care in Nigeria there is the need for concerted efforts among the Dentists, the Government and Non-Governmental Organizations.","PeriodicalId":19720,"journal":{"name":"Nigerian Postgraduate Medical Journal","volume":"7 1","pages":"134-136"},"PeriodicalIF":1.1,"publicationDate":"2010-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78622620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Implications of low oral health awareness in Nigeria","authors":"O. Sofola","doi":"10.4314/NMJ.V51I3.59903","DOIUrl":"https://doi.org/10.4314/NMJ.V51I3.59903","url":null,"abstract":"I congratulate the Nigerian Medical Association on this Golden Jubilee celebration. It is my opinion that time is apt for us all to have to reappraisal of health care delivery in Nigeria and fashion a practical and achievable way forward for the betterment of the health of the poor Nigerian. I thank the association for inviting me to participate in this symposium on 50 years of oral health in Nigeria. It is my hope and prayer that deliberations at this meeting would signal the beginning of a well planned and structured oral health care delivery system for Nigeria. My brief is to discuss the implication of low oral health awareness in Nigeria.","PeriodicalId":19720,"journal":{"name":"Nigerian Postgraduate Medical Journal","volume":"173 1","pages":"131"},"PeriodicalIF":1.1,"publicationDate":"2010-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88380770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}