Oral health & preventive dentistry最新文献

{"title":"Suppression of Streptococcus mutans Biofilm Formation and Gene Expression by PRG Barrier Coat: A Molecular and Microscopic Study for Preventing Dental Caries.","authors":"Haruka Nishimata, Yoko Kamasaki, Kyoko Satoh, Risako Kinoshita, Keisuke Omori, Tomonori Hoshino","doi":"10.3290/j.ohpd.b4928623","DOIUrl":"10.3290/j.ohpd.b4928623","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to investigate the inhibitory effect of a PRG Barrier Coat on biofilm formation and structure by Streptococcus mutans and propose an effective method for preventing dental caries.</p><p><strong>Materials and methods: </strong>Streptococcus mutans MT8148 biofilms were obtained from hydroxyapatite disks with and with- out a PRG Barrier Coat. Scanning electron microscopy (SEM) was used to observe the 12- and 24-h-cultured biofilms, while reverse-transcription polymerase chain reaction (qRT-PCR) was used to quantify caries-related genes. Biofilm adhe- sion assessments were performed on glass. Statistical analysis was performed using a two-sample t-test.</p><p><strong>Results: </strong>A statistically significant difference in Streptococcus mutans biofilm adhesion rate was observed between the con- trol and PRG Barrier Coat-coated samples (p < 0.01). However, there was no statistically significant difference in total bacter- ial count or biofilm volume (p > 0.05). SEM revealed that the PRG Barrier Coat inhibited biofilm formation by Streptococcus mutans. Real-time RT-PCR revealed that the material restricted the expression of genes associated with caries-related bio- film formation. However, the suppression of gtfD and dexB differed from that of other genes.</p><p><strong>Conclusion: </strong>PRG Barrier Coat suppressed biofilm formation by Streptococcus mutans by inhibiting the expression of in- soluble glucan synthase, which is associated with primary biofilm formation. The material also affected gene expression and altered the biofilm structure. Tooth surface-coating materials, such as PRG Barrier Coat, may improve caries preven- tion in dental practice.</p>","PeriodicalId":19696,"journal":{"name":"Oral health & preventive dentistry","volume":"22 1","pages":"73-79"},"PeriodicalIF":1.4,"publicationDate":"2024-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11619889/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139672335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Association Between Vitamin D and Early Childhood Caries: A Systematic Review and Meta-Analysis.","authors":"Shuaiqi Ji, Kai Zhao, Lei Ma, Xiaohang Chen, Dali Zheng, Youguang Lu","doi":"10.3290/j.ohpd.b4928565","DOIUrl":"10.3290/j.ohpd.b4928565","url":null,"abstract":"<p><strong>Purpose: </strong>Previous surveys have reported that children with vitamin D deficiency were likely to suffer from early childhood caries (ECC). The aim of this systematic review and meta-analysis was to determine 1. whether the status of vitamin D is intrinsically related to the occurrence of ECC and 2. the optimal level of vitamin D for the prevention of ECC.</p><p><strong>Materials and methods: </strong>The database of PubMed, Web of Science, Cochrane, Embase and Google scholar were searched for targeted literature. The eligibility criteria were observational studies in which children with ECC were compared to children without ECC in terms of their vitamin D status. Applying the Newcastle-Ottawa tool, study selection, data extraction, and risk of bias assessment were performed by 2 reviewers independently. Meta-analysis was performed using the Cochrane Collaboration's Review Manager 5.4 software.</p><p><strong>Results: </strong>501 articles were retrieved from the electronic databases; 11 studies were finally included in systematic review, 10 studies of which were submitted to meta-analysis. The 25(OH)D levels in the ECC group were statistically significantly lower compared with that in the caries-free group (WMD = -13.96, 95% CI: [-19.88,-8.03], p < 0.001), especially in regard to the association between S-ECC and vitamin D (WMD = -18.64, 95% CI: [-20.06,-17.22], p < 0.001). The subgroup analyses in terms of geographical region demonstrated that children with a level of 25(OH)D of 50-75 nmol/l were more likely to have ECC than those with over 75 nmol/l (OR = 1.42, 95% CI: [1.26,1.60], p < 0.001), with data from Asia and Europe combined for analysis Conclusions: The level of vitamin D was lower in children with ECC than in caries-free children, and the correlation between S-ECC and vitamin D was even stronger. The optimal 25(OH)D level for preventing occurrence and development of ECC was ≥ 75 nmol/l. Thus, clinicians should view the development of early caries also from a systemic perspective.</p>","PeriodicalId":19696,"journal":{"name":"Oral health & preventive dentistry","volume":"22 1","pages":"63-72"},"PeriodicalIF":1.4,"publicationDate":"2024-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11619906/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139672336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association Between the Number of Chronic Diseases and Oral Health Problems in Korean Adults.","authors":"Hee Jin Lee, Youn Huh, Sung Sunwoo","doi":"10.3290/j.ohpd.b4925339","DOIUrl":"10.3290/j.ohpd.b4925339","url":null,"abstract":"<p><strong>Purpose: </strong>The relationship between the number of chronic diseases and oral health problems is unclear. We sought to determine whether the number of chronic diseases and multimorbidity have an association with oral health problems in Korean adults.</p><p><strong>Materials and methods: </strong>Data from 23,246 adults aged ≥ 19 years, who participated in the Korea National Health and Nutrition Examination Survey from 2016 to 2019, were considered for our analyses. Participants with either masticatory or speech problems were defined as the oral health problems group. Individuals who reported having had dental treatment in the last year were defined as the dental treatment group. We used multivariable logistic regression analyses to calculate odds ratios (ORs) and 95% confidence intervals (CIs).</p><p><strong>Results: </strong>The proportions of oral health problems and dental treatment were higher in participants with multimorbidity than in those without multimorbidity (all p < 0.001). Moreover, ORs of oral health problems demonstrated a tendency to increase with the number of chronic diseases, even after adjustment (p for trend < 0.001). Compared to the participants without multimorbidity, the risk of having oral health problems increased by 25% (OR: 1.25, 95% CI: 1.12-1.39), and that of receiving dental treatment increased by 23% (OR: 1.23, 95% CI: 1.13-1.34) in patients with multimorbidity.</p><p><strong>Conclusion: </strong>The risk of oral health problems and dental treatment increased in association with the number of chronic diseases in Korean adults. The authors emphasise the risks and importance of oral health in a large population affected by multiple chronic diseases.</p>","PeriodicalId":19696,"journal":{"name":"Oral health & preventive dentistry","volume":"22 1","pages":"57-62"},"PeriodicalIF":1.4,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11619919/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139651357","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Socioeconomic Inequalities in Oral Health among Adults in Guangxi, China.","authors":"Andi Li, Tingting Zhang, Qiulin Liu, Xueting Yu, Xiaojuan Zeng","doi":"10.3290/j.ohpd.b4836051","DOIUrl":"10.3290/j.ohpd.b4836051","url":null,"abstract":"<p><strong>Purpose: </strong>To examine the relationship between socioeconomic inequalities and oral health among adults in the Guangxi province of China.</p><p><strong>Materials and methods: </strong>The present work was designed as a cross-sectional study, and comprises a secondary analysis of the Fourth National Oral Health Survey from 2015-2016. A multistage cluster sampling method was adopted for this survey, conducted in three urban and three rural districts Guangxi province. Dental examinations were conducted to determine oral health indicators: decayed teeth (DT), clinical attachment loss (CAL) and missing teeth (MT). The outcome measures were DT, CAL and MT. A structured questionnaire was used to collect data on demographic characteristics and socioeconomic status (SES). Multiple logistic regression models were used to analyse the relationship between SES and oral health by adjusting covariates.</p><p><strong>Results: </strong>The sample consisted of 651 participants aged 35-74 years. Logisitic analysis showed a statistically significant association between SES and oral health indicators. In the fully adjusted model, participants with primary education were more likely to suffer more DT (OR = 2.67, 95% CI: 1.17-6.10), teeth with CAL ≥ 4 mm (OR = 2.15, 95% CI: 1.25-3.67) and MT (OR = 3.04, 95% CI: 1.65-5.60) compared to the higher education group. Participants with secondary education exhibited a higher likelihood of experiencing increased MT compared to those in the higher education group in the fully adjusted model (OR = 3.21, 95% CI: 1.78-5.76). Household income was associated with DT and MT in the unadjusted model only.</p><p><strong>Conclusions: </strong>There was strong relationship between SES and oral health of adults. The survey suggested a relationship between low educational attainment and oral health.</p>","PeriodicalId":19696,"journal":{"name":"Oral health & preventive dentistry","volume":"22 1","pages":"31-38"},"PeriodicalIF":1.4,"publicationDate":"2024-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11619902/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139466731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Periodontal Health Knowledge and Oral Health-Related Quality of Life in Caribbean Adults.","authors":"James R Collins, Sona Rivas-Tumanyan, Arvind Babu Rajendra Santosh, Augusto Elias Boneta","doi":"10.3290/j.ohpd.b4836035","DOIUrl":"10.3290/j.ohpd.b4836035","url":null,"abstract":"<p><strong>Purpose: </strong>To identify the relationship between periodontal health knowledge and oral health-related quality of life among Caribbean adults.</p><p><strong>Materials and methods: </strong>A cross-sectional study was conducted in a representative sample from 3 Caribbean cities (weighted N = 1805). Participants completed a questionnaire on oral health knowledge, hygiene habits, and other practices, as well as the Oral Health Impact Profile-14 (OHIP-14) questionnaire. The associations between knowledge and habits and OHIP-14 score and its tertiles were evaluated using negative binomial and multinomial logistic regression models, respectively, adjusting for confounders. Odds ratios and regression coefficients were reported.</p><p><strong>Results: </strong>Participants reporting none, little, and adequate knowledge about gum health had higher odds of being in the worst tertile for OHRQoL, compared to those reporting \"good knowledge\" (ORnone vs good = 2.38, 95% CI: 1.59-3.54; ORlittle vs good = 1.82, 95% CI: 1.19-2.78; ORadequate vs good = 1.68, 95% CI: 1.11-2.57). Participants reporting toothbrushing ≥ twice/day were less likely to be in the worst tertile for OHRQoL, compared to those brushing less often (OR = 0.67, 95% CI: 0.48-0.92). Self-reported gum bleeding was associated with double the odds of being in the worse tertile (OR = 2.03, 95% CI: 1.60-2.58).</p><p><strong>Conclusion: </strong>According to the findings of this study, periodontal health knowledge is associated with reduced OHRQoL in Caribbean Adults. In addition, the frequency of brushing and the self-reported gum bleeding was related to a worse quality of life (QoL) level.</p>","PeriodicalId":19696,"journal":{"name":"Oral health & preventive dentistry","volume":"22 1","pages":"9-22"},"PeriodicalIF":1.4,"publicationDate":"2024-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11619865/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139466727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of Three Interdental Cleaning Methods for Peri-Implant Health Maintenance of Single Implant-Supported Crowns: A Randomised Clinical Trial.","authors":"Hani S AlMoharib, Mansour H AlAskar, Essam A Abuthera, Khalid A Alshalhoub, Faisal K BinRokan, Nawaf S AlQahtani, Hossam W Almadhoon","doi":"10.3290/j.ohpd.b4854607","DOIUrl":"10.3290/j.ohpd.b4854607","url":null,"abstract":"<p><strong>Purpose: </strong>To compare the effectiveness of an interproximal brush, a water flosser, and dental floss in removing plaque and reducing inflammation around implant-supported crowns.</p><p><strong>Materials and methods: </strong>A randomised controlled trial was conducted involving 45 participants with implant-supported single crowns. The participants were randomly assigned to three groups: interproximal brush, water flosser, and dental floss. Plaque index scores, gingival index scores, and interleukin-6 (IL-6) levels were assessed at baseline and after a two-week period. Statistical analysis was performed to compare the outcomes among the groups.</p><p><strong>Results: </strong>Following the second visit, improvements in plaque control were observed across all three interdental cleaning methods. The water flosser demonstrated a slight reduction in IL-6 levels (60.17 ± 3.07 vs 58.79 ± 4.04) compared to the initial visit, although this decrease was not statistically significant. Conversely, both the interdental brush and dental floss exhibited a slight increase in IL-6 levels at the second visit (60.73 ± 2.93 and 55.7 ± 10.64, respectively) compared to the mean at the first visit (58.38 ± 3.24 and 54.6 ± 2.22, respectively). Among the groups, only the interproximal brush demonstrated a statistically significant difference in IL-6 levels (p=0.008), while no statistically significant differences were observed in the dental floss and water flosser groups.</p><p><strong>Conclusion: </strong>Within the study's limitations, our findings suggest that all three methods of interdental cleaning effectively improve plaque control and reduce gingival inflammation. However, using a water flosser appears to reduce inflammation more effectively, highlighting its potential advantage over the other two methods. Further research is needed to evaluate the long-term efficacy and impact of these methods on implant survival.</p>","PeriodicalId":19696,"journal":{"name":"Oral health & preventive dentistry","volume":"22 1","pages":"51-56"},"PeriodicalIF":1.4,"publicationDate":"2024-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11619878/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139466719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Use of a Modelling Tool to Optimise the Organisation of the Demand for Primary Oral Health Care in the Brazilian Unified Health System.","authors":"Katia Miyuki Sasaki, Talitha Giovanna da Silva Neres, Erica Tatiane da Silva, Jorge Luis Lopes Zeredo","doi":"10.3290/j.ohpd.b4836027","DOIUrl":"10.3290/j.ohpd.b4836027","url":null,"abstract":"<p><strong>Purpose: </strong>To describe the use of work process modelling to optimise the organisation of the demand for oral health treatment in primary care units in Brazil.</p><p><strong>Materials and methods: </strong>The oral health care routine was at first described as the \"AS IS\" model, which was evaluated by the oral team professionals, rearranged, and further described as the \"TO BE\" model described using a business process management modelling tool. The significant increase in the demand of patients due to restrictions offered by the dental service in addition to non-urgent treatments being avoided by patients during COVID-19 pandemic was also considered.</p><p><strong>Results: </strong>Structuring the work processes in a visual way using modelling tools was useful to picture the entire treatment process and adjust when needed. The use of the managerial tool was useful to understand and reorganise the workflow of organising the demand and ultimately improve the efficiency of the resources. The use of such managerial tools helped oral health professionals to efficiently rearrange their tasks and set priorities to meet their needs.</p><p><strong>Conclusions: </strong>With the use of management tools, each unit can readjust its structures and ways of working, aiming to improve the quality of public health care services provided to patients.</p>","PeriodicalId":19696,"journal":{"name":"Oral health & preventive dentistry","volume":"22 1","pages":"1-8"},"PeriodicalIF":1.4,"publicationDate":"2024-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11619851/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139466735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Prognostic Model Based on Cisplatin-Resistance Related Genes in Oral Squamous Cell Carcinoma.","authors":"Rong Lu, Qian Yang, Siyu Liu, Lu Sun","doi":"10.3290/j.ohpd.b4836127","DOIUrl":"10.3290/j.ohpd.b4836127","url":null,"abstract":"<p><strong>Purpose: </strong>To screen for the cisplatin resistance-related prognostic signature in oral squamous cell carcinoma (OSCC) and assess its correlation with the immune microenvironment.</p><p><strong>Materials and methods: </strong>The gene expression data associated with OSCC and cisplatin-resistance were downloaded from TCGA and GEO databases. Cisplatin-resistant genes were selected through taking the intersection of differentially expressed genes (DEGs) between tumor and control groups as well as between cisplatin-resistant samples and parental samples. Then, prognosis-related cisplatin-resistant genes were further selected by univariate Cox regression and LASSO regression analyses to construct a survival prognosis model. A GSEA (gene set enrichment analysis) between two risk groups was conducted with the MSigDB v7.1 database. Finally, the immune landscape of the sample was studied using CIBERSORT. The IC50 values of 57 drugs were predicted using pRRophetic 0.5.</p><p><strong>Results: </strong>A total 230 candidate genes were obtained. Then 7 drug-resistant genes were selected for prognostic risk-score (RS) signature construction using LASSO regression analysis, including STC2, TBC1D2, ADM, NDRG1, OLR1, PDGFA and ANO1. RS was an independent prognostic factor. Additionally, a nomogram model was established to predict the 1-, 2-, and 3-year survival rates of samples. The GSEA identified several differential pathways between two risk groups, such as EMT, hypoxia, and oxidative phosphorylation. Fifteen immune cells were statistically significantly different in infiltration level between the two groups, such as macrophages M2, and resting NK cells. A total of 57 drugs had statistically significantly different IC50 values between two risk groups.</p><p><strong>Conclusion: </strong>These model genes and immune cells may play a role in predicting the prognosis and chemoresistance in OSCC.</p>","PeriodicalId":19696,"journal":{"name":"Oral health & preventive dentistry","volume":"22 1","pages":"39-50"},"PeriodicalIF":1.4,"publicationDate":"2024-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11619847/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139466714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Peri-Implant Parameters and Functional Outcome of Immediately Placed and Loaded Mandibular Overdentures: A 5-year Follow-up Study.","authors":"Abdulaziz A AlHelal, Abdulaziz A Alzaid, Saad H Almujel, Mohammed Alsaloum, Khalid K Alanazi, Ramzi O Althubaitiy, Khulud A Al-Aali","doi":"10.3290/j.ohpd.b4836045","DOIUrl":"10.3290/j.ohpd.b4836045","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the peri-implant parameters of immediately placed and loaded mandibular overdentures over a 5-year follow-up period.</p><p><strong>Materials and methods: </strong>All subjects who had been advised and planned for two-implant mandibular overdenture treatment were included in this study. The peri-implant parameters -including plaque index (PI), bleeding index (BI) and peri-implant pocket depth (PIPD) as well as marginal bone loss (MBL) - were assessed. In addition, prosthodontic parameters including abutment-, implant- and denture-related complications were assessed. Patients were evaluated at follow-up visits, scheduled at 1, 12, 24, 36, 48, and 60 months. The data distribution was analysed with the Shapiro-Wilk test. Data within follow-up categories were compared using ANOVA and the Tukey-Kramer test. A p-value < 0.05 was considered statistically significant.</p><p><strong>Results: </strong>Among the 32 participants, 19 were males and 13 were females, with a mean age of 60.5 ± 7.33. The mean plaque index (PI), bleeding index (BI) and peri-implant pocket depth (PIPD) varied over time. However, no statistically significant difference was observed in the plaque index, bleeding index and peri-implant pocket depth over time (p > 0.05). The mean value at baseline was found to be -0.9 ± 0.3. The values increased over time, with the highest value observed at 60 months 2.6 ± 0.7, which was statistically significant (p < 0.001).</p><p><strong>Conclusion: </strong>Immediately placed and loaded mandibular implant overdentures using two un-splinted implants with locator attachments showed acceptable PI, BI and PIPD at the 5-year follow-up. Statistically significantly greater marginal bone loss was observed from baseline to follow-up, but it was within acceptable limits. A moderate number of restorative and abutment complications were observed during the follow-up of IODs.</p>","PeriodicalId":19696,"journal":{"name":"Oral health & preventive dentistry","volume":"22 1","pages":"23-30"},"PeriodicalIF":1.4,"publicationDate":"2024-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11619890/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139466724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A System Dynamics Model of Caries Preventive Interventions in Thailand's School-Aged Population.","authors":"Tin Htet Oo, Sukanya Tianviwat, Songchai Thitasomakul, Phongpat Sontamino","doi":"10.3290/j.ohpd.b4721201","DOIUrl":"10.3290/j.ohpd.b4721201","url":null,"abstract":"<p><strong>Purpose: </strong>To compare the long-term effects of the Ministry of Public Health's (MOPH) caries preventive interventions for 6- to 12-year-olds (supervised toothbrushing [STB], dental sealant, and combined STB+sealant) to the base case (no intervention) using the System Dynamics Model.</p><p><strong>Materials and methods: </strong>The System Dynamics Model was used to evaluate the intervention scenarios of supervised toothbrushing (STB), sealant, and combined STB+sealant with the base-case scenario. The effectiveness data for the model's interventions were obtained from systematic reviews and meta-analyses.</p><p><strong>Results: </strong>The model determined that the caries-free population increased by 36.2%, 25.5%, and 14.5%, while the caries-affected population decreased by 8.1%, 5.5%, and 3.1% in the combined STB+sealant, sealant, and supervised toothbrushing scenarios compared to the base case at 15 years of age.</p><p><strong>Conclusion: </strong>Combined STB+sealant is the most efficacious intervention among those administered to children between the ages of 6 and 12 with permanent teeth. In addition, the System Dynamics Model could be helpful in comparing interventions or policies to determine the optimal intervention for a given population.</p>","PeriodicalId":19696,"journal":{"name":"Oral health & preventive dentistry","volume":"21 1","pages":"397-406"},"PeriodicalIF":1.4,"publicationDate":"2023-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11653775/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138478249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}