{"title":"Barriers to Oral Hygiene Self-Management Among Patients with Oral Cancer Treated with Radiotherapy: A Qualitative Study Using the COM-B Model.","authors":"Xing Gan, Lili Hou, Yuyang Li, Ying Yang, Xiaomei Zhao","doi":"10.3290/j.ohpd.c_1993","DOIUrl":"10.3290/j.ohpd.c_1993","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to assess the factors that hinder self-oral hygiene management behaviour in patients with oral cancer undergoing radiotherapy to inform intervention programme development.</p><p><strong>Materials and methods: </strong>Based on the capability, motivation, and opportunity-behaviour (COM-B) model, a qualitative study was conducted involving 18 patients with oral cancer receiving radiotherapy at a tertiary hospital from March to June 2024. Semi-structured face-to-face interviews were performed to investigate the oral hygiene self-management experience of patients. The results of the interviews were assessed by visual thematic analysis using NVivo 12 software. This article complied with the consolidated criteria for reporting qualitative research (COREQ).</p><p><strong>Results: </strong>Barriers to self-oral hygiene management in patients with oral cancer undergoing radiotherapy were grouped into three themes: (1) lack of capability (poor oral hygiene awareness, limited oral care knowledge, symptomatic distress), (2) lack of opportunity (financial burden, oral care product accessibility limitations, lack of specialised medical resources, inadequate family functioning), and (3) lack of motivation (low intrinsic motivation, heavy psychological pressure, lifestyle entrenchment).</p><p><strong>Conclusion: </strong>The capability and motivation of patients undergoing radiotherapy for oral cancer to manage their oral hygiene must be improved, along with external resources for oral hygiene management. The medical team needs to continuously improve guidance on self-oral hygiene management to meet individual needs.</p>","PeriodicalId":19696,"journal":{"name":"Oral health & preventive dentistry","volume":"23 ","pages":"329-337"},"PeriodicalIF":1.4,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12138383/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144258665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Association between Dietary Live Microbe Intake and Periodontitis in Adults: Evidence from NHANES.","authors":"Shanshan Gong, Bin Lv, Yihong Fan, Yuchang Fei","doi":"10.3290/j.ohpd.c_2026","DOIUrl":"10.3290/j.ohpd.c_2026","url":null,"abstract":"<p><strong>Purpose: </strong>To investigate the relationship between the consumption of live microbes in the diet and adult periodontitis.</p><p><strong>Materials and methods: </strong>Utilising data from the National Health and Nutrition Examination Survey (NHANES) spanning 1999-2004 and 2009-2014, 16,600 adults who underwent 24-h face-to-face dietary recall and oral health examinations were identified. Dietary live microbe intake was categorised into low, medium, and high levels. To examine the relationship between different levels of dietary live microbe intake and periodontitis, we employed logistic regression, subgroup and restricted cubic spline models.</p><p><strong>Results: </strong>Upon comprehensive covariate adjustment, low dietary live microbe intake (104 CFU/g) demonstrated a positive association with periodontitis prevalence, while medium intake (104 to 107 CFU/g) showed a negative association. Conversely, no significant associations were observed between high dietary live microbe intake (>107 CFU/g) and periodontitis. Restricted cubic spline analysis confirmed a linear association between low dietary live microbe intake. Moreover, a U-shaped dose-response relationship was identified between medium dietary live microbe intake and periodontitis prevalence.</p><p><strong>Conclusions: </strong>Moderate intake of medium live microbe food may be more conducive to avoiding the occurrence of periodontitis.</p>","PeriodicalId":19696,"journal":{"name":"Oral health & preventive dentistry","volume":"23 ","pages":"253-264"},"PeriodicalIF":1.4,"publicationDate":"2025-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12131903/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144209092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Association of Body Mass Index and Waist Circumference with Periodontal Disease.","authors":"Bogeun Lee, Sojung Mun","doi":"10.3290/j.ohpd.c_2017","DOIUrl":"10.3290/j.ohpd.c_2017","url":null,"abstract":"<p><strong>Purpose: </strong>Obesity results in many chronic diseases, and appropriate measurement of obesity will accurately evaluate the risks of other diseases. Studies have primarily focused on the correlation between a single obesity index and periodontal diseases, and studies analysing the correlation between obesity and periodontal diseases using two or more obesity indices are scarce. This study was designed to evaluate the risk of periodontal disease by combining body mass index (BMI) and waist circumference (WC).</p><p><strong>Materials and methods: </strong>We analysed BMI and WC of 12,689 adults who participated in the Korea National Health and Nutrition Survey from 2016 to 2018. Participants' general characteristics included gender, age, marital status, education, income level, smoking, alcohol use, physical activity, oral health examination, tooth brushing, diabetes, hypertension, and dyslipidemia. periodontal diseases were determined using the Community Periodontal Index (CPI). BMI and WC were used as obesity indices. BMI was classified into underweight, normal, and high; WC was classified into normal and high. Based on the classifications, participants were categorised into six levels of obesity.</p><p><strong>Results: </strong>The risk of periodontal disease was higher in groups 4 (odds ratio [OR]: 2.88; [95% confidence interval [95% CI]: 2.16-4.04]) and Group 6 (OR: 2.91; 95% CI: 2.22-3.83) where WC was high than in Group 5 (OR: 1.79; 95% CI: 1.34-2.40), where BMI was high.</p><p><strong>Conclusion: </strong>The prevalence of periodontal disease is higher among obese WC subjects. High WC could be a potential risk factor for periodontal disease in adults.</p>","PeriodicalId":19696,"journal":{"name":"Oral health & preventive dentistry","volume":"23 ","pages":"271-277"},"PeriodicalIF":1.4,"publicationDate":"2025-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12131901/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144209102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effectiveness of Hyaluronic Acid Injection in the Reconstruction of Interdental Papilla: A Systematic Review.","authors":"Alexia Larderet, Catherine Petit, Olivier Huck, Pierre-Yves Gegout","doi":"10.3290/j.ohpd.c_2057","DOIUrl":"10.3290/j.ohpd.c_2057","url":null,"abstract":"<p><strong>Purpose: </strong>The loss of interdental papilla (IDP) is a significant esthetic concern often associated with black triangles (BT). BT are potential consequences of periodontitis, orthodontic treatment, and anatomical variations due to their influence on the critical distance from the contact point to the bone crest. Various treatment options, both invasive and non-invasive, have been proposed to address this issue. Recently, the injection of hyaluronic acid (HA) has emerged as a promising minimally invasive alternative. This systematic review aims to evaluate the effectiveness of HA injections for IDP reconstruction in esthetic zones in humans.</p><p><strong>Materials and methods: </strong>A comprehensive literature search was conducted using Cochrane library, PubMed/MEDLINE, and Embase databases with keywords like 'interdental papilla,' 'hyaluronic acid,' and 'human'. Change in BT mean height (mm) was considered as the primary outcome while percentage of change in BT area was considered as the secondary outcome.</p><p><strong>Results: </strong>177 articles were screened, and 15 eligible studies were included, focusing on the therapeutic effects of HA injections on interdental papilla dimensions in humans. Clinical trials have demonstrated varying degrees of success and patient satisfaction with HA injections for IDP reconstruction over a period of 4 weeks to 25 months. Several studies showed significant improvements related to BT height and width, although complete papilla fill remains unpredictable. Higher success rates were observed in the maxilla compared to the mandible, and patients with thicker gingival phenotype showed better outcomes. The initial size of the defect, the number of HA applications and the analysis method significantly influenced the results.</p><p><strong>Conclusion: </strong>HA injections look promising for IDP reconstruction. However, the need for multiple injections and long-term efficacy remains to be fully understood. Further research is necessary to standardise treatment protocols and evaluate long-term outcomes and patient satisfaction comprehensively.</p>","PeriodicalId":19696,"journal":{"name":"Oral health & preventive dentistry","volume":"23 ","pages":"279-290"},"PeriodicalIF":1.4,"publicationDate":"2025-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12138381/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144216428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rachel Swed, Elina Nourmand, Nina K Anderson, Rafael Delgado-Ruiz, Georgios Romanos
{"title":"The Effect of Antimicrobial Agents on Implant Surface Wettability Changes: An In-Vitro Study.","authors":"Rachel Swed, Elina Nourmand, Nina K Anderson, Rafael Delgado-Ruiz, Georgios Romanos","doi":"10.3290/j.ohpd.c_2039","DOIUrl":"10.3290/j.ohpd.c_2039","url":null,"abstract":"<p><strong>Purpose: </strong>The goal of this in-vitro study was to determine the impact of the antimicrobial disinfecting agents chlorhexidine (Peridex) and an herbal extract (StellaLife) on the wettability of four implant surfaces: titanium machined (TM), titanium-SLA (SLA), titanium alloy (TA), and zirconia.</p><p><strong>Materials and methods: </strong>Each implant surface in the form of a disk was disinfected with 0.12% chlorhexidine (Peridex, group 1), peppermint-flavoured herbal extract (StellaLife, group 2), and saline solution as the control liquid (group 3). Using a calibrated micro-syringe, 7.5 µl of each liquid were dispensed on the center of each disk (n = 180). Then, a goniometer was used to measure contact angles between the droplet and the disk surface to evaluate the wettability (hydrophilicity) of each implant surface. The mean from 20 contact angle measurements per liquid and implant surface was calculated. Comparative statistical analysis was performed with ANOVA and Bonferroni correction at the p 0.05 level of significance.</p><p><strong>Results: </strong>The Bonferroni post-hoc comparison revealed a statistically significant difference with improved wettability for group 2 compared to groups 1 and 3 for rough-surfaced titanium-SLA implant surfaces.</p><p><strong>Conclusion: </strong>Overall, titanium implants may have improved hydrophilicity when rinsed with herbal extract antimicrobial agents compared to chlorhexidine.</p>","PeriodicalId":19696,"journal":{"name":"Oral health & preventive dentistry","volume":"23 ","pages":"299-303"},"PeriodicalIF":1.4,"publicationDate":"2025-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12138382/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144216443","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Does the Use of Different Remineralisation Agents in a 14-day Demineralisation/Remineralisation Cycle Affect the Bond Strength to Artificial Carious Enamel Surfaces?","authors":"Özgül Carti Dörterler, Fatma Yilmaz, Saniye Eren Halici, Aysegul Demirbas, Elif Yigit","doi":"10.3290/j.ohpd.c_1977","DOIUrl":"10.3290/j.ohpd.c_1977","url":null,"abstract":"<p><strong>Purpose: </strong>To examine the effect of applying different forms of remineralising agents during a pH-cyclinge on the bond strength of a universal adhesive applied in the etch-and-rinse mode and the types of fractures that occur after shear bond-strength testing.</p><p><strong>Materials and methods: </strong>84 human molars were divided into seven equal groups. Groups 1 (intact enamel) and 2 (artificially demineralised enamel) served as the positive and negative controls, respectively. In the experimental groups (3-7), the enamel was treated using remineralising agents during a 14-day pH-cycling protocol. Group 3: fluoride gel; group 4: fluoride varnish; group 5: Tooth Mousse; group 6: MI Paste Plus; group 7: MI Varnish. Afterwards, the molars' crowns were sectioned off, and a universal adhesive (G2-Bond Universal) was applied to the buccal surfaces of these samples using etch-and-rinse mode. Nanohybrid resin composite restorations (G-aenial Posterior) were then placed, and shear bond-strength testing was performed. The effects of remineralisation agents on artificial carious lesions were evaluated using scanning electron microscopy/energy-dispersive analysis.</p><p><strong>Results: </strong>The fluoride varnish and MI varnish groups show statistically significantly lower shear bond strengths compared to the positive control group (p0.001). The bond strength to all remineralising agents was higher than that of the negative control group. All tested agents promoted remineralisation in demineralised areas of the enamel surface.</p><p><strong>Conclusions: </strong>Remineralisation agents in forms other than varnish do not negatively affect the shear-bond strength to enamel surfaces.</p>","PeriodicalId":19696,"journal":{"name":"Oral health & preventive dentistry","volume":"23 ","pages":"241-251"},"PeriodicalIF":1.4,"publicationDate":"2025-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12131905/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144209103","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Volkan Arısan, Alper Sağlanmak, Ata Anıl, S Volkan Arıcı, Anton Sculean
{"title":"Photodynamic Therapy as an Adjunct to Resective and Regenerative Surgical Treatment of Peri-Implantitis: A Prospective Cohort of 72 Patients Followed for 18 Months.","authors":"Volkan Arısan, Alper Sağlanmak, Ata Anıl, S Volkan Arıcı, Anton Sculean","doi":"10.3290/j.ohpd.c_2078","DOIUrl":"10.3290/j.ohpd.c_2078","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the efficacy of photodynamic therapy (PDT) as an adjunct to resective and regenerative surgical peri-implantitis treatment (open flap debridement via scaling and smoothening of the implant surface [implantoplasty]) combined with guided bone regeneration (GBR) in a patient cohort of a university clinic.</p><p><strong>Materials and methods: </strong>Seventy-two patients were treated with either conventional therapy (CON) or conventional therapy plus PDT. CON included mechanical debridement, implantoplasty, and GBR. Clinical parameters, including marginal bone level (MBL), probing pocket depth (PPD) and bleeding on probing (BOP) were assessed at baseline, 6, 12, and 18 months. The primary outcome was the resolution of the infection using a composite success criterion.</p><p><strong>Results: </strong>After 18 months, infection resolution rates were 75% for CON and 80% for PDT groups (p = 0.75). Kaplan-Meier survival analysis showed no statistically significant difference for the infection resolution between groups (log-rank test, p = 0.6221). Both groups demonstrated statistically significant MBL gain after 6 months (mean 2.59 mm ± 1.25), with no statistically significant differences between groups throughout the follow-up. PPD was statistically significantly lower in the PDT group (two-way ANOVA, p = 0.018). BOP scores decreased initially but showed an increasing trend in both groups over time (chi-squared test, p = 0.045), with no statistically significant differences between groups.</p><p><strong>Conclusion: </strong>PDT as an adjunct to conventional peri-implantitis treatment with GBR resulted in statistically significantly lower PPD values. However, no additional benefits were observed for infection resolution, maintenance of infection-free status, MBL or BOP. Initial improvements in both groups followed by gradual recurrences in clinical parameters over 18 months.</p>","PeriodicalId":19696,"journal":{"name":"Oral health & preventive dentistry","volume":"23 ","pages":"305-314"},"PeriodicalIF":1.4,"publicationDate":"2025-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12135869/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144216442","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Analysis of Oral Health Status and Dental Caries-Related Factors in Children of Zhoushan.","authors":"Songtao Pan, Di Miao, Yingna Xu, Chenting Xin","doi":"10.3290/j.ohpd.c_2029","DOIUrl":"10.3290/j.ohpd.c_2029","url":null,"abstract":"<p><strong>Purpose: </strong>This study was initiated to assess the oral health status and identify factors associated with dental caries in children from Zhoushan.</p><p><strong>Methods and materials: </strong>A total of 125 children aged 5-12 years old were selected for oral examinations at the paediatric dentistry department of our hospital. The dental caries status of the children was examined and recorded, and a questionnaire was administered to their caregivers. The questionnaire collected data on patients' awareness of oral health, supervision of children's toothbrushing, assessment of brushing effectiveness, as well as dietary habits, oral behaviours, and oral healthcare practices. Univariate and multivariate logistic regression analyses were employed to analyse the relationships between the prevalence of dental caries and the selected variables.</p><p><strong>Results: </strong>The caries rate among the 125 children was 62.40%. Logistic regression analysis showed that the use of fluoride toothpaste, brushing ≥ 2 times per day, and brushing after eating were protective factors against dental caries in children (OR < 1, P < 0.05). In contrast, age at initiation of brushing > 3 years, consumption of sweets and beverages ≥ 2 times per week, and frequent bedtime eating were likely to increase dental caries risk in children (OR > 1, P < 0.05).</p><p><strong>Conclusion: </strong>In view of the identified factors contributing to dental caries in children, it is important to strengthen oral hygiene education for both parents and children. Promoting standardised dental caries prevention and treatment practices and cultivating good oral hygiene habits among children are essential for improving their oral health.</p>","PeriodicalId":19696,"journal":{"name":"Oral health & preventive dentistry","volume":"23 ","pages":"265-269"},"PeriodicalIF":1.4,"publicationDate":"2025-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12131902/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144209091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pierre-Jean Berat, Vincent de Andrade, Nolwenn Regnault, Annabelle Tenenbaum, Sylvie Azogui-Levy
{"title":"Oral Health Conditions of Preschool Children Among Birth Cohort Studies: A Scoping Review.","authors":"Pierre-Jean Berat, Vincent de Andrade, Nolwenn Regnault, Annabelle Tenenbaum, Sylvie Azogui-Levy","doi":"10.3290/j.ohpd.c_1990","DOIUrl":"10.3290/j.ohpd.c_1990","url":null,"abstract":"<p><strong>Purpose: </strong>Oral health is an integral part of health and well-being. Through birth cohorts, it is possible to identify health conditions and pathways of exposure that occur earlier in life. The objective of this study was to identify the data collected by birth cohorts regarding the oral health of children aged 0 to 5 years and to determine the relationship between their dental health status and their environment.</p><p><strong>Materials and methods: </strong>Five databases were queried: PubMed, Web of Science, Scopus, Embase, and Dentistry & Oral Sciences Source. Eligible articles presented data on children's oral health before their 6th birthday, based on birth cohorts. They could be based on clinical, epidemiological, or self-reported oral health data obtained during at least one follow-up between birth and the age of 6 years.</p><p><strong>Results: </strong>3083 articles were identified in biomedical literature databases. After exclusions for various reasons, 359 abstracts and finally 145 full-length articles were read. A total of 101 articles were included in the analysis. These 101 articles came from 43 cohorts on 5 continents. They were published between October 1980 and January 2022. The most frequently identified theme was early childhood caries and its associated factors. Other themes were also studied: quality of life in relation to oral health, children's use of dental care, eruption of primary teeth, enamel anomalies, dental trauma, occlusion, and parafunctions in childhood.</p><p><strong>Conclusion: </strong>Preschool children's oral health has been widely studied in terms of caries and its risk factors. However, biopsychosocial determinants have to date been insufficiently studied in these birth cohorts.</p>","PeriodicalId":19696,"journal":{"name":"Oral health & preventive dentistry","volume":"23 ","pages":"315-328"},"PeriodicalIF":1.4,"publicationDate":"2025-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12135870/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144216430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Arvi Keinänen, Johanna Snäll, Jaana Hagström, Johanna Uittamo
{"title":"History of Oral Mucosal Lesions in Oral Squamous Cell Carcinoma Patients.","authors":"Arvi Keinänen, Johanna Snäll, Jaana Hagström, Johanna Uittamo","doi":"10.3290/j.ohpd.c_2028","DOIUrl":"10.3290/j.ohpd.c_2028","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the occurrence of previous mucosal dysplasia in patients with oral squamous cell carcinoma (OSCC) and to charaterise patient profile, types of previous oral mucosal lesions, and care-seeking in relation to earlier mucosal findings.</p><p><strong>Materials and methods: </strong>Retrospective data of OSCC patients with a primary tumour were collected. The primary outcome variable was any history of oral mucosal findings; the secondary outcome variable was a history of previous oral mucosal dysplasia. The primary predictor variable was the mode of seeking treatment. Patient and tumour-related variables were compared between patients with and without anamnestic mucosal changes or findings.</p><p><strong>Results: </strong>A total of 528 patients were included in the study. Of these patients, 169 (32.0%) had a history of an oral mucosal lesion. Oral mucosal dysplasia was detected in 34 patients (6.4%) before the OSCC diagnosis. Patients who had a history of heavy alcohol use were less likely to have a history of any mucosal lesions or dysplasia (adjusted odds ratio [aOR] 0.350, 95% confidence interval [CI] 0.215-0.571, p 0.001 and aOR 0.235, 95% CI 0.070-0.795, p = 0.020). Tumours were detected more often in conjunction with routine appointments in patients with a history of any mucosal lesions (aOR 2.671, 95% CI 1.704-4.187, p 0.001) and in those with previously detected dysplasia (aOR 6.195, 95% CI 3.004-12.774, p 0.001).</p><p><strong>Conclusions: </strong>The results emphasise the importance of careful examination and close follow-up of findings in the oral mucosa.</p>","PeriodicalId":19696,"journal":{"name":"Oral health & preventive dentistry","volume":"23 ","pages":"291-297"},"PeriodicalIF":1.4,"publicationDate":"2025-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12135868/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144216429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}