Oral health & preventive dentistry最新文献

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The Potential Allergic Role of Mast Cells to Orthodontic Appliance in Orthodontic-Induced Gingival Enlargement. 正畸诱导的牙龈增大中肥大细胞对正畸矫治器的潜在过敏作用。
IF 1.7 4区 医学
Oral health & preventive dentistry Pub Date : 2026-09-04 DOI: 10.3290/j.ohpd.c_2801
Amal Ali Ibrahim, Omneya Emam Ahmed, Gihan A Balbola, Amany M Taha, Doaa Adel Habba, Basma Badr Hasaneen, Naglaa S El-Kilani
{"title":"The Potential Allergic Role of Mast Cells to Orthodontic Appliance in Orthodontic-Induced Gingival Enlargement.","authors":"Amal Ali Ibrahim, Omneya Emam Ahmed, Gihan A Balbola, Amany M Taha, Doaa Adel Habba, Basma Badr Hasaneen, Naglaa S El-Kilani","doi":"10.3290/j.ohpd.c_2801","DOIUrl":"https://doi.org/10.3290/j.ohpd.c_2801","url":null,"abstract":"<p><strong>Background: </strong>Gingival mast cells (MCs) are strategically scattered throughout connective tissue and adhere to the endothelium to convert local impulses into systemic signals and attract additional immune effector cells. Numerous mediators, such as histamine, cytokines, and proteases, modulate these interaction pathways.</p><p><strong>Objectives: </strong>The purpose of this study was to determine and compare MC count in the gingival enlargement tissue of patients receiving orthodontic treatment versus patients having plaque-induced gingival enlargement without orthodontic treatment, utilising hematoxylin and eosin (H&E) staining, toluidine blue (TB), and CD117 (c-kit) immunohistochemistry (IHC) as a specific marker for MC identification.</p><p><strong>Methods and materials: </strong>This study involved 30 patients who were divided into three groups: Group 1 included 10 patients with clinically healthy gingival tissue that intentionally needed crown lengthening. Group 2 included 10 cases of plaque-induced gingival enlargement in individuals without orthodontic treatment. Group 3 included 10 cases of orthodontic gingival enlargement in individuals receiving orthodontic treatment. Patients received non-surgical periodontal therapy and oral hygiene instructions. After the plaque control phase, with a Gingival Index (GI) = 0 and no Bleeding on Probing (BoP), the gingiva was surgically treated. During the surgical procedure, the excised gingival margin was collected for histological examination with H&E, TB special stain, and c-kit to count the MCs.</p><p><strong>Results: </strong>The gingiva of patients in group 3 was characterised by more frequent epithelial changes (mild hyperplasia of the basal layer and spongiosis), a stronger degree of inflammation, including band-like inflammatory infiltrates and individual inflammatory cells, and a milder degree of fibrosis, compared to group 2. In addition, a significant increase in the number of MCs was observed in group 3 compared with groups 2 and 1. c-kit was a more specific marker for MCs than for TB.</p><p><strong>Conclusion: </strong>Orthodontic-induced gingival enlargement showed a significantly higher number of mast cells than plaque-induced gingival enlargement, and this involvement of MCs, particularly, may be associated with mast cell activation and degranulation. These findings may suggest an immunological role for MCs in the pathogenesis of orthodontically induced gingival enlargement.</p>","PeriodicalId":19696,"journal":{"name":"Oral health & preventive dentistry","volume":"24 ","pages":"767-773"},"PeriodicalIF":1.7,"publicationDate":"2026-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148888050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association of Subjective Oral Status and Oral Health Behaviours With a History of Systemic Disease Among Community-Dwelling Older Adults. 社区老年人主观口腔状况和口腔健康行为与全身性疾病史的关系
IF 1.7 4区 医学
Oral health & preventive dentistry Pub Date : 2026-09-04 DOI: 10.3290/j.ohpd.c_2807
Rumi Nishimura, Haruka Fukutani, Marin Ishigami, Maho Omoda, Mayuka Asaeda, Yukoh Muraki, Noriyasu Uchibori, Mariko Naito
{"title":"Association of Subjective Oral Status and Oral Health Behaviours With a History of Systemic Disease Among Community-Dwelling Older Adults.","authors":"Rumi Nishimura, Haruka Fukutani, Marin Ishigami, Maho Omoda, Mayuka Asaeda, Yukoh Muraki, Noriyasu Uchibori, Mariko Naito","doi":"10.3290/j.ohpd.c_2807","DOIUrl":"10.3290/j.ohpd.c_2807","url":null,"abstract":"<p><strong>Purpose: </strong>Inadequate oral hygiene and management affect oral health and are associated with systemic diseases. Although systemic disease history may relate to subjective oral status and oral health behaviours, these associations remain insufficiently examined. This study investigated the associations between systemic disease history, subjective oral status, and oral health behaviours among community-dwelling older adults.</p><p><strong>Methods and materials: </strong>We analysed data from 979 individuals aged 65-85 years, residing in Higashiura-cho, Aichi Prefecture, who participated in a 2018 group examination and completed a self-administered questionnaire. Multivariable logistic regression was used to evaluate associations between oral-related variables ('concerns about teeth and mouth condition', 'use of interdental brushes and dental floss', and 'experience of oral hygiene instruction') and histories of systemic diseases (cancer, myocardial infarction, stroke, hypertension, diabetes, liver disease, lung disease, mental illness, and bone disease).</p><p><strong>Results: </strong>The mean age was 73.0 ± 5.2 years, and 52.4% were female. No significant associations were observed between 'concerns about teeth and mouth condition', 'use of interdental brushes and dental floss', and systemic disease history. However, participants who had received oral hygiene instruction had higher odds of a history of hypertension (odds ratio: 1.4; 95% confidence interval: 1.0-2.0).</p><p><strong>Conclusion: </strong>Among community-dwelling older adults, receiving oral hygiene instruction was positively associated with a history of hypertension. As the data were self-reported, findings should be interpreted with caution. Dental hygienists should consider patients' systemic health status, particularly hypertension, when providing oral hygiene instruction.</p>","PeriodicalId":19696,"journal":{"name":"Oral health & preventive dentistry","volume":"24 ","pages":"775-781"},"PeriodicalIF":1.7,"publicationDate":"2026-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13543021/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148888006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Retrospective Cohort Study of Medication-Related Osteonecrosis of the Jaw (MRONJ) Prevention. 药物相关性颌骨骨坏死(MRONJ)预防的回顾性队列研究。
IF 1.7 4区 医学
Oral health & preventive dentistry Pub Date : 2026-09-04 DOI: 10.3290/j.ohpd.c_2794
Nasimeh Baghalipour, Omid Moztarzadeh, Bacem Othman, Yasmin Dehghani, Lukas Hauer
{"title":"A Retrospective Cohort Study of Medication-Related Osteonecrosis of the Jaw (MRONJ) Prevention.","authors":"Nasimeh Baghalipour, Omid Moztarzadeh, Bacem Othman, Yasmin Dehghani, Lukas Hauer","doi":"10.3290/j.ohpd.c_2794","DOIUrl":"10.3290/j.ohpd.c_2794","url":null,"abstract":"<p><strong>Purpose: </strong>Medication-related osteonecrosis of the jaw (MRONJ) is a serious complication that can arise in patients receiving antiresorptive or antiangiogenic therapy. Despite known predisposing factors, effective prophylaxis is currently little used. We therefore sought to assess the standardised prevention protocols that are used in our institution for reducing MRONJs among at-risk patients and to quantify the consistency of the effects.</p><p><strong>Methods and materials: </strong>This retrospective cohort study analysed 422 dental extraction records from 126 patients who had received antiresorptive or antiangiogenic therapy. The extractions were classified into four risk levels based on medication class, cumulative treatment duration, comorbidity burden and immunosuppression status. The effect of the prevention protocol was estimated using Mantel-Haenszel stratified analysis, with the risk level as the stratifying variable, and the homogeneity of the effect was assessed using the Breslow-Day test.</p><p><strong>Results: </strong>MRONJ developed in 94.1% of extractions performed without prevention protocols and in only 6.7% with prophylactic protocols; Mantel-Haenszel stratified analysis - adjusting for the baseline risk level - produced a common OR of 0.0044 (95% CI: 0.0010-0.0195, p 0.0001). Stratum-specific estimates were consistent across all three risk levels, and the Breslow-Day test confirmed the homogeneity of the effect.</p><p><strong>Conclusions: </strong>Mantel-Haenszel stratified analysis confirmed consistent protective effects of the applied prevention protocols, with different proportionality, across every risk level. This study proposes the first stratified quantification of prevention protocol effectiveness across a validated composite risk scoring system.</p>","PeriodicalId":19696,"journal":{"name":"Oral health & preventive dentistry","volume":"24 ","pages":"783-790"},"PeriodicalIF":1.7,"publicationDate":"2026-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13543025/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148887995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Trust in Artificial Intelligence-Generated Oral Health Information and Its Influence on Patient Decision-Making: A Cross-Sectional Study. 信任人工智能生成的口腔健康信息及其对患者决策的影响:一项横断面研究。
IF 1.7 4区 医学
Oral health & preventive dentistry Pub Date : 2026-09-02 DOI: 10.3290/j.ohpd.c_2805
Berrak Ulu Emir, Bilkan Kara, Sayna Behkar, Erkan Özcan
{"title":"Trust in Artificial Intelligence-Generated Oral Health Information and Its Influence on Patient Decision-Making: A Cross-Sectional Study.","authors":"Berrak Ulu Emir, Bilkan Kara, Sayna Behkar, Erkan Özcan","doi":"10.3290/j.ohpd.c_2805","DOIUrl":"10.3290/j.ohpd.c_2805","url":null,"abstract":"<p><strong>Purpose: </strong>Artificial intelligence (AI)-assisted applications are increasingly used to obtain health-related information; however, concerns remain regarding the reliability of AI-generated responses and their influence on patient attitudes and decision-making. This study aimed to evaluate the use of AI-assisted applications among patients, their trust in AI-generated information, and the influence of these applications on oral-health-related decision-making.</p><p><strong>Methods and materials: </strong>This cross-sectional questionnaire-based study included 430 patients attending the Department of Periodontology. Participants completed a structured questionnaire evaluating AI-assisted application use, trust in AI-generated oral health information, and the effects of AI on oral-health-related attitudes. Categorical variables were presented as frequencies (n) and percentages (%). Associations between categorical variables were analysed using the chi-square test. Effect sizes were evaluated using Cramér's V coefficient. Statistical significance was set at p 0.05.</p><p><strong>Results: </strong>A total of 430 participants completed the questionnaire, including 300 AI users. AI usage rates were generally similar across reasons for admission, although the highest usage was observed among individuals attending routine check-ups (18/19; 94.7%). In treatment-related decisions, most participants preferred dentists' opinions over AI-generated recommendations (80.8%; p 0.01). Trust was significantly associated with AI usage frequency (p 0.01), whereas education level was significantly associated with AI usage (p 0.001). Education level was also associated with willingness to consult AI-assisted programmes regarding dentist-created treatment plans (p = 0.033).</p><p><strong>Conclusion: </strong>AI-assisted applications have become an important part of health information-seeking behaviour, particularly among younger and more educated individuals. However, patients remain cautious about the reliability of AI-generated information and continue to prioritise professional dental expertise in treatment-related decisions.</p>","PeriodicalId":19696,"journal":{"name":"Oral health & preventive dentistry","volume":"24 ","pages":"759-766"},"PeriodicalIF":1.7,"publicationDate":"2026-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13536940/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148875755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Detection Efficacy of a Novel Disposable Dental Protective Device versus Medical Goggles in Reducing Splatter Exposure during Tooth Preparation: A Randomised Controlled Trial. 一种新型一次性牙齿保护装置与医用护目镜在牙齿准备过程中减少飞溅暴露的检测效果:一项随机对照试验。
IF 1.7 4区 医学
Oral health & preventive dentistry Pub Date : 2026-08-31 DOI: 10.3290/j.ohpd.c_2803
Qinying Zhu, Xiaping Wang, Yanhong Zhang, Junjie Wang, Yi Zhang, Qianju Wu
{"title":"Detection Efficacy of a Novel Disposable Dental Protective Device versus Medical Goggles in Reducing Splatter Exposure during Tooth Preparation: A Randomised Controlled Trial.","authors":"Qinying Zhu, Xiaping Wang, Yanhong Zhang, Junjie Wang, Yi Zhang, Qianju Wu","doi":"10.3290/j.ohpd.c_2803","DOIUrl":"10.3290/j.ohpd.c_2803","url":null,"abstract":"<p><strong>Objective: </strong>This randomised controlled trial compared a novel disposable dental protective device with traditional medical goggles regarding splatter interception, patient experience, and safety during tooth preparation.</p><p><strong>Methods: </strong>Seventy patients were allocated to use either the novel device (experimental group, n = 35) or medical goggles (control, n = 35) during standardised tooth preparation without suction. The primary outcome was the weight of captured splatter. Secondary outcomes included the total patient-reported outcome score derived from a seven-item, five-point Likert questionnaire and facial pressure sensation assessed using a visual analogue scale (VAS).</p><p><strong>Results: </strong>The experimental group captured significantly more splatter (1.23 ± 0.35 g) than the control group (0.76 ± 0.21 g, mean difference 0.47 g, 95% confidence interval 0.33 to 0.61, P 0.001). Patients rated the novel device significantly higher with regard to the total subjective score, material softness, hygiene, protection, comfort, and overall satisfaction (P 0.001), and reported lower facial pressure (VAS 1.80 ± 1.19 vs 4.50 ± 2.10, P 0.001). No serious adverse events occurred.</p><p><strong>Conclusion: </strong>The novel disposable device demonstrated superior splatter interception, better patient acceptance, and less facial pressure compared to medical goggles, showing promise for enhancing facial protection in dentistry.</p>","PeriodicalId":19696,"journal":{"name":"Oral health & preventive dentistry","volume":"24 ","pages":"747-757"},"PeriodicalIF":1.7,"publicationDate":"2026-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13531766/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148866309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of Hyaluronic Acid in the Surgical Treatment of Periodontitis: A Systematic Review. 透明质酸在牙周炎手术治疗中的作用:系统综述。
IF 1.7 4区 医学
Oral health & preventive dentistry Pub Date : 2026-08-26 DOI: 10.3290/j.ohpd.c_2760
Zocko Ange Désiré Pockpa, Camille Bechina, Marie Boutet, Zahi Badran, Assem Soueidan, Xavier Struillou
{"title":"Effects of Hyaluronic Acid in the Surgical Treatment of Periodontitis: A Systematic Review.","authors":"Zocko Ange Désiré Pockpa, Camille Bechina, Marie Boutet, Zahi Badran, Assem Soueidan, Xavier Struillou","doi":"10.3290/j.ohpd.c_2760","DOIUrl":"10.3290/j.ohpd.c_2760","url":null,"abstract":"<p><strong>Purpose: </strong>Hyaluronic acid (HA) is a naturally occurring polymer synthesised endogenously in the human body, with distinctive physicochemical and biological properties such as excellent biocompatibility and biodegradability. These characteristics have led to extensive research into its therapeutic potential, particularly in the management of inflammatory diseases. This systematic review aimed to evaluate the effects of HA on clinical outcomes in the surgical treatment of periodontitis.</p><p><strong>Methods and materials: </strong>This review was registered with PROSPERO (CRD42024493296) and conducted according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) 2020 guidelines. A systematic search was performed in PubMed, Cochrane, and Scopus up to September 2025. Randomised controlled trials assessing HA clinical outcomes in the surgical treatment of periodontitis were included.</p><p><strong>Results: </strong>Nine RCTs including a total of 343 patients were analysed. Sample sizes ranged from 14 to 60 participants, with follow-up periods between 3 and 24 months. The adjunctive use of HA in the surgical treatment of periodontitis led to consistent improvements, with probing depth (PD) reductions of 2.0-3.5 mm and CAL gains of 2.0-3.8 mm after 6-12 months. Radiographic evaluations also showed greater bone fill in intrabony defects.</p><p><strong>Conclusion: </strong>Within the limits of available randomised controlled trials, HA shows potential as an adjunct in the surgical management of periodontitis. Although reported improvements in clinical parameters are encouraging, evidence remains heterogeneous and requires confirmation through standardised, long-term studies.</p>","PeriodicalId":19696,"journal":{"name":"Oral health & preventive dentistry","volume":"24 ","pages":"687-693"},"PeriodicalIF":1.7,"publicationDate":"2026-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13508247/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148819138","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Causal Effects of Oral Microbiome, Circulating Metabolites, and Inflammatory Proteins on Recurrent Aphthous Stomatitis: A Two-Sample Mendelian Randomization Study. 口腔微生物组、循环代谢物和炎症蛋白对复发性口腔炎的因果影响:一项双样本孟德尔随机研究。
IF 1.7 4区 医学
Oral health & preventive dentistry Pub Date : 2026-08-26 DOI: 10.3290/j.ohpd.c_2774
Shaobin Long, Wei Zeng, Simin Huang, Lixian Yang, Rong Zhou, Keke Zhu, Xuan Zhu
{"title":"Causal Effects of Oral Microbiome, Circulating Metabolites, and Inflammatory Proteins on Recurrent Aphthous Stomatitis: A Two-Sample Mendelian Randomization Study.","authors":"Shaobin Long, Wei Zeng, Simin Huang, Lixian Yang, Rong Zhou, Keke Zhu, Xuan Zhu","doi":"10.3290/j.ohpd.c_2774","DOIUrl":"10.3290/j.ohpd.c_2774","url":null,"abstract":"<p><strong>Purpose: </strong>Recurrent aphthous stomatitis (RAS) affects 20% of the global population with unclear etiology and limited treatment options. While observational studies suggest associations with oral microbiome dysbiosis and metabolic alterations, causal relationships have not been established. Using Mendelian randomization, the aim of this study was threefold: 1. to systematically investigate the causal architecture underlying RAS; 2. to partition the total effect of identified microbial taxa into direct and mediator-adjusted components; 3. to determine whether specific circulating metabolites and circulating inflammatory proteins mediate the microbiome-RAS relationship.</p><p><strong>Materials and methods: </strong>We conducted two-sample Mendelian randomization (MR) using oral microbiome, metabolomics, inflammatory proteins, and RAS genome-wide association study summary statistics (GWAS). Univariable MR assessed direct causal effects, while multivariable MR evaluated mediation pathways. Sensitivity analyses included MR-Egger, weighted median, and MR-PRESSO.</p><p><strong>Results: </strong>The order Clostridiales demonstrated protective effects against RAS (OR=0.851, 95% CI: 0.759-0.954, p=0.006). Among 36 causally associated metabolites, myo-inositol (OR=1.619), sphingosine 1-phosphate (OR=1.672), and hexadecadienoate (OR=1.825) increased RAS risk, while 4-acetylphenol sulfate (OR=0.606) and acetylcarnitine (OR=0.604) conferred protection. No inflammatory proteins showed statistically significant associations. Two-step mediation analysis identified sphingomyelin (d18:1/22:1, d18:2/22:0, d16:1/24:1) as a metabolic intermediate in the Clostridiales-RAS pathway, with the direct protective effect of Clostridiales remaining statistically significant after adjustment for sphingomyelin levels.</p><p><strong>Conclusions: </strong>This study provides genetic evidence supporting causal relationships linking the oral microbiome and metabolites to RAS, and identified Clostridiales as protective against RAS, but found multiple lipid mediators as risk factors. The interplay between Clostridiales and sphingolipid metabolism provides candidate therapeutic targets for RAS management through microbiome modulation or metabolic intervention.</p>","PeriodicalId":19696,"journal":{"name":"Oral health & preventive dentistry","volume":"24 ","pages":"737-746"},"PeriodicalIF":1.7,"publicationDate":"2026-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13520203/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148819174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cytotoxic Effects of Flowable Composite Resins with Different Resin Matrix Compositions on L929 Fibroblasts. 不同树脂基质组成的可流动复合树脂对L929成纤维细胞的细胞毒作用。
IF 1.7 4区 医学
Oral health & preventive dentistry Pub Date : 2026-08-26 DOI: 10.3290/j.ohpd.c_2787
Sema Yazıcı Akbıyık, Cansu Yikici Col, Songul Kilic, Demet Kacaroglu
{"title":"Cytotoxic Effects of Flowable Composite Resins with Different Resin Matrix Compositions on L929 Fibroblasts.","authors":"Sema Yazıcı Akbıyık, Cansu Yikici Col, Songul Kilic, Demet Kacaroglu","doi":"10.3290/j.ohpd.c_2787","DOIUrl":"10.3290/j.ohpd.c_2787","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the cytotoxic effects of flowable composite resins with different resin matrix characteristics on L929 fibroblast cells.</p><p><strong>Materials and methods: </strong>Five flowable composite resins (GrandioSO Flow [GSF; VOCO Dental, Cuxhaven, Germany], EverX Flow [EXF; GC Europe, Leuven, Belgium], Admira Fusion Flow [AFF; VOCO Dental], Stark Bulk Fill Flow [SBFF; President Dental, Allershausen, Germany], and Estelite Bulk Fill Flow [EBFF; Tokuyama Dental, Tokyo, Japan]) were prepared as standardised discs (5 × 2 mm). Extracts obtained after 1 and 7 days of incubation were applied to L929 fibroblast cultures at different concentrations (direct, 1:2, 1:5, and 1:10 dilutions) for 24 and 48 hours. Cell viability was assessed using the 3-(4,5-dimethylthiazol-2-yl)-2,5 diphenyl tetrazolium bromide (MTT) assay. Data were analysed using a two-way analysis of variance (ANOVA) and Tukey post hoc test (α = 0.05).</p><p><strong>Results: </strong>Direct exposure to all material extracts significantly reduced cell viability compared with the control group (P 0.0001). Cell viability increased with increasing dilution for all materials. EBFF and EXF consistently demonstrated the highest viability values and the most favourable biocompatibility profiles. In contrast, GSF exhibited the lowest cell viability values and the highest cytotoxic potential, particularly under direct exposure. AFF and SBFF showed intermediate responses. Overall, cell viability values were generally higher after 48 hours of exposure than after 24 hours.</p><p><strong>Conclusion: </strong>The cytotoxic effects of the flowable composite resins were concentration- and time-dependent. Although all tested materials generally maintained satisfactory cell viability under the evaluated conditions, significant differences were observed among the investigated materials. EBFF and EXF exhibited the most favourable biocompatibility, whereas GSF showed comparatively lower cell viability. Resin matrix characteristics, together with polymerisation-related factors, may influence the biological response of flowable composite resins.</p>","PeriodicalId":19696,"journal":{"name":"Oral health & preventive dentistry","volume":"24 ","pages":"669-677"},"PeriodicalIF":1.7,"publicationDate":"2026-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13509130/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148819140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sinus-Plate Augmentation Method (SPAM) for Lateral Ridge Augmentation in the Maxillary Posterior Area: A Case Series. 窦板增强法(SPAM)用于上颌后区侧脊增强:一个病例系列。
IF 1.7 4区 医学
Oral health & preventive dentistry Pub Date : 2026-08-26 DOI: 10.3290/j.ohpd.c_2763
Cosmin Dima, Raluca Cosgarea
{"title":"Sinus-Plate Augmentation Method (SPAM) for Lateral Ridge Augmentation in the Maxillary Posterior Area: A Case Series.","authors":"Cosmin Dima, Raluca Cosgarea","doi":"10.3290/j.ohpd.c_2763","DOIUrl":"10.3290/j.ohpd.c_2763","url":null,"abstract":"<p><strong>Purpose: </strong>This paper describes a novel surgical technique (Sinus-Plate Augmentation Method [SPAM]) using autologous sinus plate bone for posterior lateral maxillary augmentation during sinus lifting and dental implant insertion.</p><p><strong>Materials and methods: </strong>Eight partially edentulous patients aged 52-71 years old (7 females, 2 smokers) with severe horizontal alveolar bone resorption in the maxillary posterior areas, were surgically treated as follows: lateral bone augmentation was performed by harvesting the vestibular bone wall of the sinus window and using a xenogeneic bone graft, followed by external sinus lifting and implant insertion. Seven patients were followed-up for 12-18 months, while one patient was followed-up for 36 months.</p><p><strong>Results: </strong>A total of 24 implants were inserted simultaneously with SPAM and sinus lifting. Post-operative healing was uneventful in all cases. Horizontal alveolar bone gain ranged between 9.28±1.2 mm post-operatively and 8.37±1.5 mm at the 19.5-month follow-up. A statistically significant gain in alveolar bone width of 2.55±1.47 mm was present at the follow-up.</p><p><strong>Conclusion: </strong>SPAM seems to be a feasible surgical technique for the horizontal reconstruction of moderate to severely resorbed posterior maxillae, concomitant to external sinus lifting and implant insertion.</p>","PeriodicalId":19696,"journal":{"name":"Oral health & preventive dentistry","volume":"24 ","pages":"703-717"},"PeriodicalIF":1.7,"publicationDate":"2026-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13509141/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148819156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Nutrition Habits and Oral Conditions Within a Representative Swiss Cohort of Adult Subjects. 营养习惯和口腔状况的代表性瑞士队列成人受试者。
IF 1.7 4区 医学
Oral health & preventive dentistry Pub Date : 2026-08-26 DOI: 10.3290/j.ohpd.c_2764
Maurus Kurt Jaeggi, Christian Tennert, Maria Prasinou, Martin Schimmel, Andrea Roccuzzo, Guglielmo Campus, Roberta Borg-Bartolo
{"title":"Nutrition Habits and Oral Conditions Within a Representative Swiss Cohort of Adult Subjects.","authors":"Maurus Kurt Jaeggi, Christian Tennert, Maria Prasinou, Martin Schimmel, Andrea Roccuzzo, Guglielmo Campus, Roberta Borg-Bartolo","doi":"10.3290/j.ohpd.c_2764","DOIUrl":"10.3290/j.ohpd.c_2764","url":null,"abstract":"<p><strong>Purpose: </strong>This observational, cross-sectional study investigated the association between nutrition and oral health status in adults aged ≥ 45 years in the Canton of Bern, Switzerland.</p><p><strong>Methods and materials: </strong>Citizens throughout the Canton of Bern, Switzerland, chosen by random sampling, were included in the study according to predefined inclusion and exclusion criteria. Participants filled out questionnaires covering their nutritional aspects and oral hygiene habits before undergoing clinical examination, including the assessment of oral hygiene, dental caries, periodontal disease, as well as prosthetic rehabilitation. Chi-square/Fisher tests, as well as binary and multinomial logistic regression, were performed to investigate potential associations.</p><p><strong>Results: </strong>275 participants (mean age 69.7 years; female 44%; male 56%) were included in the study. An association between higher age and poorer oral hygiene (RR = 1.07, 95% CI [1.024, 1.117]), higher caries experience (DMFT > 15: RR = 1.152, 95% CI [1.1, 1.207]), and higher prevalence of periodontal disease was observed (OR = 1.038, 95% CI [1.013, 1.063]). Participants who ate vegetables daily had a lower risk of having dental caries (DMFT > 15: RR = 0.437, 95% CI [0.237, 0.806]) and/or poor oral hygiene (RR = 0.309, 95% CI [0.141, 0.674]). Participants who ate nuts regularly presented with better oral hygiene than those who did not eat nuts (RR = 0.356, 95% CI [0.134-0.950]).</p><p><strong>Conclusion: </strong>Within its limitations, the present study demonstrated the importance of a healthy diet containing fibre-rich foods for the achievement and maintenance of good oral health.</p>","PeriodicalId":19696,"journal":{"name":"Oral health & preventive dentistry","volume":"24 ","pages":"679-685"},"PeriodicalIF":1.7,"publicationDate":"2026-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13508251/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148819201","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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