Effect of Using Mouthwash Containing Cibotium barometz J. Smith on Cariogenic Bacteria and Acid-producing Ability of Saliva: A Randomised Blinded Clinical Trial.

IF 1.4 4区医学 Q3 DENTISTRY, ORAL SURGERY & MEDICINE

Oral health & preventive dentistry Pub Date : 2024-07-23 DOI:10.3290/j.ohpd.b5574011

Yu-Rin Kim, Seoul-Hee Nam

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引用次数: 0

Abstract

Purpose: To examine the anti-caries effect of mouthwashes containing Cibotium barometz J. Smith (CB), a natural substance, and compare it with chlorhexidine and saline solution.

Materials and methods: A randomised, blinded clinical trial was conducted on 76 study participants. The differences between the 3 gargle groups (saline gargle: SAL; chlorhexidine gargle: CHX; CB gargle group: CB) and the differences over time (baseline, after 1 week, after 2 weeks) were compared. To this end, ANOVA was performed on caries-related clinical indicators (e.g. O'Leary plaque index, caries activity, and satisfaction).

Results: The O'Leary index, caries activity, and saliva tests, gradually improved in group CB at one and two weeks. In the case of bacterial tests, unlike SAL and CHX, only in group CB did the decrease occur one and two weeks later. The caries-related indicators decreased significantly over time in group CB compared to SAL and CHX groups, and there was also a statistically significant difference in interaction between groups and time (p<0.05).

Conclusions: The mouthwash containing CB extract showed statistically significant improvement in biofilm adhesion as well as the saliva and bacterial tests compared to SAL and CHX. However, since there were differences in the initial oral conditions of the three groups, additional long-term research is needed through crossover clinical trials to supplement these.

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使用含 Cibotium barometz J. Smith 的漱口水对致癌细菌和唾液产酸能力的影响：随机盲法临床试验。

目的：研究含有天然物质 Cibotium barometz J. Smith（CB）的漱口水的抗龋齿效果，并将其与洗必泰和生理盐水进行比较：对 76 名参与者进行了随机、盲法临床试验。比较了 3 个漱口组（生理盐水漱口组：SAL；洗必泰漱口组：CHX；CB 漱口组：CB）之间的差异以及不同时间段（基线、1 周后、2 周后）的差异。为此，对龋病相关临床指标（如 O'Leary 牙菌斑指数、龋病活动度和满意度）进行了方差分析：结果：CB 组的 O'Leary 指数、龋齿活动度和唾液测试在一周和两周后逐渐改善。在细菌检测方面，与 SAL 和 CHX 不同，只有 CB 组在一周和两周后才出现下降。与 SAL 组和 CHX 组相比，CB 组的龋齿相关指标随着时间的推移明显下降，而且各组与时间之间的交互作用差异也有统计学意义（p 结论：CB 组的龋齿相关指标随着时间的推移明显下降，而且各组与时间之间的交互作用差异也有统计学意义：与 SAL 和 CHX 相比，含有 CB 提取物的漱口水在生物膜粘附性以及唾液和细菌测试方面都有显著的统计学改善。不过，由于三组的初始口腔状况存在差异，因此还需要通过交叉临床试验进行更多的长期研究来补充。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Oral health & preventive dentistry DENTISTRY, ORAL SURGERY & MEDICINE-

CiteScore

3.00

自引率

0.00%

发文量

审稿时长

>12 weeks

期刊介绍： Clinicians, general practitioners, teachers, researchers, and public health administrators will find this journal an indispensable source of essential, timely information about scientific progress in the fields of oral health and the prevention of caries, periodontal diseases, oral mucosal diseases, and dental trauma. Central topics, including oral hygiene, oral epidemiology, oral health promotion, and public health issues, are covered in peer-reviewed articles such as clinical and basic science research reports; reviews; invited focus articles, commentaries, and guest editorials; and symposium, workshop, and conference proceedings.