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[EDITOR'S NOTE]. [编者按]。
Nippon Ganka Gakkai zasshi Pub Date : 2016-06-01
Kyoko Ohno-Matsui
{"title":"[EDITOR'S NOTE].","authors":"Kyoko Ohno-Matsui","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":19670,"journal":{"name":"Nippon Ganka Gakkai zasshi","volume":"120 6","pages":"468"},"PeriodicalIF":0.0,"publicationDate":"2016-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34728986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Ocular Manifestations Induced by Diversification of Anticancer Agents--Focus on Corneal Disorders]. [多种抗癌药物诱导的眼部表现——以角膜疾病为重点]。
Nippon Ganka Gakkai zasshi Pub Date : 2016-06-01
Taiichiro Chikama
{"title":"[Ocular Manifestations Induced by Diversification of Anticancer Agents--Focus on Corneal Disorders].","authors":"Taiichiro Chikama","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":19670,"journal":{"name":"Nippon Ganka Gakkai zasshi","volume":"120 6","pages":"417-8"},"PeriodicalIF":0.0,"publicationDate":"2016-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34728159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Efficacy and Safety of A0001 (Brilliant Blue G250) for Internal Limiting Membrane Staining and Peeling: Phase III Investigator-initiated Multicenter Clinical Trial]. [A0001 (Brilliant Blue G250)用于内限制膜染色和剥离的有效性和安全性:研究者发起的III期多中心临床试验]。
Nippon Ganka Gakkai zasshi Pub Date : 2016-06-01
Hiroshi Enaida, Akito Hirakata, Masahito Ohji, Kohji Nishida, Toshiaki Kubota, Nahoko Ogata, Koh-Hei Sonoda, Makiko Uchiyama, Junji Kishimoto, Koji Todaka, Yoichi Nakanishi, Tatsuro Ishibashi
{"title":"[Efficacy and Safety of A0001 (Brilliant Blue G250) for Internal Limiting Membrane Staining and Peeling: Phase III Investigator-initiated Multicenter Clinical Trial].","authors":"Hiroshi Enaida,&nbsp;Akito Hirakata,&nbsp;Masahito Ohji,&nbsp;Kohji Nishida,&nbsp;Toshiaki Kubota,&nbsp;Nahoko Ogata,&nbsp;Koh-Hei Sonoda,&nbsp;Makiko Uchiyama,&nbsp;Junji Kishimoto,&nbsp;Koji Todaka,&nbsp;Yoichi Nakanishi,&nbsp;Tatsuro Ishibashi","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Purpose: </strong>To investigate the efficacy and safety of A0001 (brilliant blue G250) for visualization of the internal limiting membrane (ILM) during and after vitrectomy.</p><p><strong>Methods: </strong>Patients (n = 31) requiring ILM peeling during vitrectomy were enrolled in this clinical trial. After injection of A0001 (range: 0.0625 to 0. 125 mg), the staining grade and the peeling ease of the ILM were evaluated in five steps (levels 0 to 4). The safety of A0001 was investigated for 7 days after surgery.</p><p><strong>Results: </strong>From the evaluation of a primary endpoint by the Independent Data Monitoring Committee (IDMC) and a secondary endpoint by each surgeon, A0001 was effective in all cases at three or more levels ( ≥ level 2 was defined as effective) for evaluation of the grade of visualization and operating ease. Adverse events occurring in two or more cases included elevated intraocular pressure, eye pain, eye discharges, and retinal bleeding. One serious adverse event was a case of unclosed macular hole after vitrectomy, but the patient recovered after reoperation.</p><p><strong>Conclusions: </strong>A0001 was effective and safe for visualization of the ILM during vitrectomy, and there was an improvement in ease of operation.</p>","PeriodicalId":19670,"journal":{"name":"Nippon Ganka Gakkai zasshi","volume":"120 6","pages":"439-48"},"PeriodicalIF":0.0,"publicationDate":"2016-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34728982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[MESSAGE FROM THE TRUSTEES]. [来自受托人的信息]。
Nippon Ganka Gakkai zasshi Pub Date : 2016-06-01
Akira Murakami
{"title":"[MESSAGE FROM THE TRUSTEES].","authors":"Akira Murakami","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":19670,"journal":{"name":"Nippon Ganka Gakkai zasshi","volume":"120 6","pages":"415"},"PeriodicalIF":0.0,"publicationDate":"2016-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34728158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[A Case of a Corneal Disorder after Breast Cancer Treatment with Nab-paclitaxel]. [nab -紫杉醇治疗乳腺癌后角膜病变1例]。
Nippon Ganka Gakkai zasshi Pub Date : 2016-06-01
Yuka Hosotani, Takanobu Morimatsu, Masashi Takata, Osamu Mimura
{"title":"[A Case of a Corneal Disorder after Breast Cancer Treatment with Nab-paclitaxel].","authors":"Yuka Hosotani,&nbsp;Takanobu Morimatsu,&nbsp;Masashi Takata,&nbsp;Osamu Mimura","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>We report a case of a corneal disorder after breast cancer treatment with a microtubule inhibitor, nab-paclitaxel (Abraxane).</p><p><strong>Case: </strong>A 55-year-old woman, who was referred to our clinic, presented with blurred vision. 2 weeks previously, she had been undergoing treatment with nab-paclitaxel, trastuzumab and pertuzumab. Visual acuity was 20/60 in right eye and 20/40 in left eye. Slit-lamp examination showed an atypical epithelium invasion of the cornea in both eyes and small epithelial defect in left eye. After the nab-paclitaxel treatment was discontinued the corneal findings improved. 4 months later, visual acuity was 20/15 in right eye and 20/20 in left eye.</p><p><strong>Conclusions: </strong>Nab-paclitaxel can cause severe corneal disorders, but the possibility that trastuzumab and pertuzumab combination therapy is associated with these disorders cannot be denied. Clinicians should consider the possibility of the side effects caused by systemic administration in cases of corneal disorders of uncertain etiology.</p>","PeriodicalId":19670,"journal":{"name":"Nippon Ganka Gakkai zasshi","volume":"120 6","pages":"449-53"},"PeriodicalIF":0.0,"publicationDate":"2016-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34728983","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[PROGRESS REPORT FROM THE STRATEGIC PLANNING COMMITTEE]. [战略规划委员会的进度报告]。
Nippon Ganka Gakkai zasshi Pub Date : 2016-06-01
Akira Negi
{"title":"[PROGRESS REPORT FROM THE STRATEGIC PLANNING COMMITTEE].","authors":"Akira Negi","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":19670,"journal":{"name":"Nippon Ganka Gakkai zasshi","volume":"120 6","pages":"457-8"},"PeriodicalIF":0.0,"publicationDate":"2016-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34728985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Intravitreal Triamcinolone Acetonide for Persistent Diabetic Macular Edema after Vitrectomy]. [玻璃体切除术后玻璃体内注射曲安奈德治疗持续性糖尿病黄斑水肿]。
Nippon Ganka Gakkai zasshi Pub Date : 2016-06-01
Atsushi Ichio, Masahiko Sugimoto, Mineo Kondo
{"title":"[Intravitreal Triamcinolone Acetonide for Persistent Diabetic Macular Edema after Vitrectomy].","authors":"Atsushi Ichio,&nbsp;Masahiko Sugimoto,&nbsp;Mineo Kondo","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Purpose: </strong>To determine whether intravitreal triamcinolone acetonide (IVTA) is effective in resolving edema in eyes with persistent diabetic macular edema (DME) after vitrectomy.</p><p><strong>Patients and methods: </strong>Sixteen eyes of 16 patients were given 4 mg IVTA after vitrectomy for DME. The best-corrected visual acuity (BCVA), central macular thickness (CMT), and average threshold (AT) of the central retina were determined during the 24 weeks follow-up period. Patients were divided into two groups; early treatment group and late treatment group.</p><p><strong>Results: </strong>The BCVA was significantly improved at 12 weeks, the CMT was significantly improved at 24 weeks, and the AT was significantly improved at 4 weeks after IVTA (repeated ANOVA, p < 0.05). The BCVA was more significantly improved in the early treatment group than in the late treatment group at 4 and 12 weeks (unpaired t test, p < 0.05).</p><p><strong>Conclusion: </strong>Our results indicate that IVTA should be considered as treatment for patients with persistent DME after vitrectomy, especially with early treatment patients.</p>","PeriodicalId":19670,"journal":{"name":"Nippon Ganka Gakkai zasshi","volume":"120 6","pages":"429-38"},"PeriodicalIF":0.0,"publicationDate":"2016-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34728161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[The Origin of the Disorder Named "Ryoku-naisho (Glaucoma)"]. [一种名为“青光眼”的疾病的起源]。
Nippon Ganka Gakkai zasshi Pub Date : 2016-05-01
Hidenoba Tanihara, Ikuko Abe
{"title":"[The Origin of the Disorder Named \"Ryoku-naisho (Glaucoma)\"].","authors":"Hidenoba Tanihara,&nbsp;Ikuko Abe","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>It is said that the description of an ocular disorder related to the color of the sea in the Hippocratic Corpus is the oldest medical reference to glaucoma. In the early Edo period in Japan, the Books of Secrets of the Majima school, describe a disorder called aosokohi. This nomenclature is believed to be based upon the Five Elements' Theory (Wu-Xing Thought)in ancient China, which assigned five colors for intraocular disorders (\"naisho/sokohi\" in Japanese), blue (\"ao\" in Japanese), red, yellow, white and black. In Japanese literature, in late Edo period, \"ryokunaisho (glaucoma)\" appeared after the publication of Dutch-Japanese translation by Dutch scholars. The Japanese name is thought to derive trom \"Glaukos\" which means green in ancient Greek. Since the Meiji period, \"ryoku-naisho (glaucoma)\" has been used inmost textbooks including those by foreign teachers and the works of Jujiro Komoto, the first Professor at the Department of Ophthalmology of (Tokyo)Imperial University.</p>","PeriodicalId":19670,"journal":{"name":"Nippon Ganka Gakkai zasshi","volume":"120 5","pages":"369-81"},"PeriodicalIF":0.0,"publicationDate":"2016-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34585038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Problems Related to Anti-Vascular Endothelial Growth Factor Treatment for Retinal Vein Occlusion]. 【抗血管内皮生长因子治疗视网膜静脉闭塞的相关问题】。
Nippon Ganka Gakkai zasshi Pub Date : 2016-05-01
Motohiro Kamei
{"title":"[Problems Related to Anti-Vascular Endothelial Growth Factor Treatment for Retinal Vein Occlusion].","authors":"Motohiro Kamei","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":19670,"journal":{"name":"Nippon Ganka Gakkai zasshi","volume":"120 5","pages":"361-3"},"PeriodicalIF":0.0,"publicationDate":"2016-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34585036","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Clinical Characteristics of Rhegmatogenous Retinal Detachment in Highly Myopic and Phakic Eyes]. [高度近视和散光眼孔源性视网膜脱离的临床特点]。
Nippon Ganka Gakkai zasshi Pub Date : 2016-05-01
Tadashi Orihara, Kazunari Hirota, Reiji Yokota, Daisuke Kunita, Yuji Itoh, Tosho Rii, Takashi Koto, Tomoyuki Hiraoka, Makoto Inoue, Akito Hirakata
{"title":"[Clinical Characteristics of Rhegmatogenous Retinal Detachment in Highly Myopic and Phakic Eyes].","authors":"Tadashi Orihara,&nbsp;Kazunari Hirota,&nbsp;Reiji Yokota,&nbsp;Daisuke Kunita,&nbsp;Yuji Itoh,&nbsp;Tosho Rii,&nbsp;Takashi Koto,&nbsp;Tomoyuki Hiraoka,&nbsp;Makoto Inoue,&nbsp;Akito Hirakata","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate clinical characteristics of rhegmatogenous retinal detachment in high myopic and phakic eyes.</p><p><strong>Subjects and method: </strong>The subjects were 1174 eyes of phakic rhegmatogenous retinal detachment detected in 1199 eyes that underwent initial vitreoretinal surgery between April 2006 and March 2011. Eyes with macular hole retinal detachment or secondary retinal detachment were excluded. The 486 eyes with high myopia (spherical equivalent ≤ -6.0 D or axial length ≥ 26.5 mm) and the 688 eyes with non-high myopia were compared.</p><p><strong>Results: </strong>The mean age was significantly younger in the high myopia group (42.7 ± 14.2 years old, p < 0.001) with a single peak of higher incidence in 40 years old. The retinal detachment caused by retinal hole was significantly frequent in the high myopia group (p < 0.001) and that caused by retinal tear was less frequent (p = 0.021). The initial retinal attachment rate and the final attachment rate were not significant. In the fellow eye of the high myopia group, the incidence of retinal detachment and lattice degeneration were more frequent (16.7%, 20.4%, respectively).</p><p><strong>Conclusions: </strong>The incidences of the retinal detachment in younger age and those caused by retinal holes were higher in the high myopia group. Higher incidence of retinal detachment and lattice degeneration in the fellow eyes of the high myopia group indicated that careful observation also in the fellow eyes was recommended.</p>","PeriodicalId":19670,"journal":{"name":"Nippon Ganka Gakkai zasshi","volume":"120 5","pages":"382-9"},"PeriodicalIF":0.0,"publicationDate":"2016-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34585039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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