{"title":"[Factors Affecting Outcomes of Repeated Penetrating Keratoplasty].","authors":"Shinobu Yamamoto, Machiko Shimmura-Tomita, Yoshiyuki Satake, Seika Shimazaki-Den, Shigeto Shimmura, Jun Shimazaki","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Purpose: </strong>To investigate prognosis for repeated penetrating keratoplasty (PKP) and factors that affect the outcome.</p><p><strong>Methods: </strong>We retrospectively investigated graft survival rates, 1-year postoperative best-corrected visual acuity and irreversible rejection rates in 108 eyes of 106 patients that had repeated PKP. Factors that might affect the outcome were, age, number of previous PKP, original diseases, history of glaucoma and rejection and the use of postoperative immunosuppressant were also studied.</p><p><strong>Results: </strong>Individual-factor analysis showed that history of rejection and postoperative immunosuppressant significantly increased the risk of postoperative rejection. Multi-factor analysis showed that graft survival rate was significantly lower among cases that had systemic immunosuppressants (steroids and cyclosporine). One year postoperative best-corrected visual acuity was significantly worse in cases that had history of glaucoma. In cases with history of rejection, systemic administration of postoperative immunosuppressants was significantly associated with postoperative irreversible rejection.</p><p><strong>Conclusion: </strong>History of rejection and glaucoma tend to have poor outcome, and the outcome might not improve by postoperative immunosuppressants.</p>","PeriodicalId":19670,"journal":{"name":"Nippon Ganka Gakkai zasshi","volume":"119 9","pages":"625-31"},"PeriodicalIF":0.0,"publicationDate":"2015-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34096240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[A Case of Corneal Injury due to Herbicide Containing Paraquat: Effectiveness of 2% Rebamipide Eye Drops].","authors":"Makoto Uno","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Herbicides containing paraquat are widely used and have occasionally been causing ocular damage. The initial ocular injury caused by paraquat tends to worsen within a few days to 1 week. The toxicity of paraquat is based on the oxidative stress induced by reactive oxygen species.</p><p><strong>Case: </strong>An 82-year-old woman who had been exposed to herbicide containing paraquat in her left eye presented at Koumeikan Eye Clinic 2 days after the incident. Moderate corneal erosion was diagnosed and treated with ordinary medication, but the corneal lesion worsened. After administration of topical 2% rebamipide eye drops, the corneal lesion resolved rapidly.</p><p><strong>Conclusion: </strong>Because of its role as a radical scavenger, rebamipide has great potential for treatment of corneal injuries caused by herbicides such as paraquat.</p>","PeriodicalId":19670,"journal":{"name":"Nippon Ganka Gakkai zasshi","volume":"119 8","pages":"521-6"},"PeriodicalIF":0.0,"publicationDate":"2015-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34190978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Antimicrobial Effects of Iodine-Polyvinyl Alcohol Ophthalmic and Eye Washing Solution (PA * IODO) with Special Reference to its Temperature, Concentration and Time and its Preservation Stability].","authors":"Hiroshi Hatano, Masako Sakamoto, Kazuo Hayashi, Seigo Kamiya","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Purpose: </strong>Temperature, concentration and time are the three factors that affect the inactivation capacity of iodine antiseptics. We investigated the effect of these factors on the microbe inactivation of Iodine-Polyvinyl Alcohol ophthalmic and eye washing solution (PA * IODO), and also investigated the preservation conditions on stability of the inactivation activity of the PA * IODO.</p><p><strong>Methods: </strong>Test microbes were mixed with PA * IODO, varying the three factors. The live microbes were counted after each reaction. The effects of plugging and preservation temperature were investigated to determine the preserving stability.</p><p><strong>Results: </strong>The inactivation capacity of PA * IODO tended to decrease in almost all microbes tested at 4 degrees C. Twenty times or less diluted PA * IODO killed almost all microbes completely. The time effect was more marked in viruses. Plugging and low-temperature made iodine concentration in diluted PA * IODO remain relatively high.</p><p><strong>Conclusions: </strong>The concentration of PA * IODO affected the inactivation ability more than the temperature and time, although all the three factors correlated positively to the inactivation. For preservation the diluted PA * IODO needed plugging and low temperature.</p>","PeriodicalId":19670,"journal":{"name":"Nippon Ganka Gakkai zasshi","volume":"119 8","pages":"503-10"},"PeriodicalIF":0.0,"publicationDate":"2015-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34190975","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[On: Clinical Features of 19 Cases of Fisher Syndrome].","authors":"Akihiko Oohira","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":19670,"journal":{"name":"Nippon Ganka Gakkai zasshi","volume":"119 8","pages":"527"},"PeriodicalIF":0.0,"publicationDate":"2015-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34190979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Clinical Results of Tinted Aspherical Multifocal IOL with +2.5 Diopter Near Add Power SN6AD2 (SV25T0)].","authors":"Hiroko Bissen-Miyajima, Ken Hayashi, Manabu Hirasawa, Mami Yoshino, Kunihiko Nakamura, Motoaki Yoshida, Miki Masumoto, Hiroshi Sasaki","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the efficacy and safety of a newly developed diffractive multifocal intraocular lens (IOL) with +2.5 diopter near add power (SN6AD2, Alcon), whose theoretical distance for near focus is 50 cm.</p><p><strong>Methods: </strong>This study included 128 eyes of 64 patients (23 men and 41 women, average age: 66.7 ± 7.2 years) following cataract removal at Tokyo Dental College Suidobashi Hospital and Hayashi Eye Hospital. Visual acuities (VAs) at distance, 1 m, 50 cm and 40 cm, and questionnaires were evaluated until 1 year postoperatively.</p><p><strong>Results: </strong>At 1 year postoperatively, mean bilateral logMAR VAs were uncorrected -0.09 (5 m), 0.01 (1 m), 0.07 (50 cm), 0.18 (40 cm), distance corrected 0.01 (1 m), 0.08 (50 cm), 0.19 (40 cm), best corrected -0.17 (5 m), 0.00 (50 cm). From the patient's questionnaires, light or moderate glare was noticed in 17.5%, 4.8%, light or moderate halo was notice in 19.0%, 4.8% of the total patients.</p><p><strong>Conclusion: </strong>This IOL provides good distance to intermediate VAs and better near VA compared to monofocal IOL.</p>","PeriodicalId":19670,"journal":{"name":"Nippon Ganka Gakkai zasshi","volume":"119 8","pages":"511-20"},"PeriodicalIF":0.0,"publicationDate":"2015-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34190976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Prevalence of Epiretinal Membrane Using Optical Coherence Tomography].","authors":"Yoshihiro Noda, Saori Yamazaki, Masanori Kawano, Yoshihisa Goto, Shin-ichi Otsuka, Yuichiro Ogura","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Purpose: </strong>To investigated the prevalence and risk factors of epiretinal membrane (ERM).</p><p><strong>Subjects and method: </strong>Five hundred eyes of 500 patients (202 men and 298 women, average age 74.9), who underwent cataract surgery in Otsuka Eye Clinic one or two months before the survey, were examined using spectral-domain optical coherence tomography (OCT).</p><p><strong>Results: </strong>ERMs were observed in 43 eyes (8.6%) and 31 eyes (6.2%) were diagnosed as idiopathic ERM. Idiopathic ERM was significantly associated with age, but not with gender, best-corrected visual acuity after cataract surgery or diabetes. Only 4.8 percent of idiopathic ERM patients had subjective symptoms detected by the Amsler chart.</p><p><strong>Conclusions: </strong>The prevalence of ERM was 8.6% and of idiopathic ERM 6.2%. The most prevalent risk factor of idiopathic ERM was aging.</p>","PeriodicalId":19670,"journal":{"name":"Nippon Ganka Gakkai zasshi","volume":"119 7","pages":"445-50"},"PeriodicalIF":0.0,"publicationDate":"2015-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33935104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Variations of Intraocular Pressure with the Variations of Measurement Environment in Patients with Primary Open Angle Glaucoma].","authors":"Kiyoshi Yaoeda, Atsushi Fukushima, Motohiro Shirakashi, Tetsuya Togano, Takeo Fukuchi","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objectives: </strong>To examine the variations in intraocular pressure (IOP) occuring upon changes in clinical premises' relocation in patients with primary open angle glaucoma (POAG).</p><p><strong>Subjects and methods: </strong>Two hundred and twenty-four eyes of 224 patients with POAG were examined. We compared the IOP values measured with an identical noncontact tonometer (NCT) (CT-90A) obtained on May 2014 (IOP514) before the clinical premises' relocation, and those obtained on June (IOP614), July or August (IOP7814) 2014 after relocation. To examine the systematic errors of the NCT, Bland-Altman plot analysis was applied.</p><p><strong>Results: </strong>IOP614 (12.2 ± 2.7 mmHg) and IOP7814 (12.1 ± 2.7mmHg) were significantly lower than IOP514 (13.1 ± 2.9 mmHg) (p < 0.001). IOP614 was also lower than IOP514, both in the β-blocker and prostaglandin analogue groups. When these values were adjusted using those obtained one year before the clinical relocation to take seasonal variations into consideration, IOP after relocation was lower than IOP before relocation (p < 0.001). Proportional bias was not detected (r = 0.082; p = 0.999).</p><p><strong>Conclusion: </strong>There was a variation in IOP determined by the identical noncontact tonometer between before and after the clinical premises' relocation in patients with POAG.</p>","PeriodicalId":19670,"journal":{"name":"Nippon Ganka Gakkai zasshi","volume":"119 7","pages":"451-6"},"PeriodicalIF":0.0,"publicationDate":"2015-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33935105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}