Ophthalmic Plastic and Reconstructive Surgery最新文献

筛选
英文 中文
Photochemical Crosslinking of Tarsal Collagen as a Treatment for Eyelid Laxity: Evaluation in Ex Vivo Human Tissue. 光化学交联跗骨胶原蛋白治疗眼睑松弛:活体人体组织评估。
IF 1.2 4区 医学
Ophthalmic Plastic and Reconstructive Surgery Pub Date : 2025-01-01 Epub Date: 2024-05-09 DOI: 10.1097/IOP.0000000000002709
Alexandra I Manta, Nadja E Pop, Robert G Tripon, Florina Vultur, Shuko Suzuki, Bogdan A Cordos, Carmen C Radu, Timur Hogea, Cosmin Carasca, Karin U Horvath, George A Muntean, Vasile C Siserman, Ovidiu S Cotoi, Mark H B Radford, Traian V Chirila
{"title":"Photochemical Crosslinking of Tarsal Collagen as a Treatment for Eyelid Laxity: Evaluation in Ex Vivo Human Tissue.","authors":"Alexandra I Manta, Nadja E Pop, Robert G Tripon, Florina Vultur, Shuko Suzuki, Bogdan A Cordos, Carmen C Radu, Timur Hogea, Cosmin Carasca, Karin U Horvath, George A Muntean, Vasile C Siserman, Ovidiu S Cotoi, Mark H B Radford, Traian V Chirila","doi":"10.1097/IOP.0000000000002709","DOIUrl":"10.1097/IOP.0000000000002709","url":null,"abstract":"<p><strong>Purpose: </strong>Experimental investigation in human eyelids to confirm that exposing excised tarsal plates to ultraviolet-A radiation can induce a stiffening effect through the riboflavin-photosensitized crosslinking of tarsal collagen.</p><p><strong>Methods: </strong>Thirteen tarsal plates excised from nonfrozen human cadavers were irradiated with ultraviolet-A rays (365 nm wavelength) at an irradiance of 75 mW/cm 2 for 3 minutes, equivalent to a radiation fluence of 13.5 J/cm 2 , in the presence of a riboflavin derivative as a photosensitizer. The tensile stress (strength) and Young's modulus (stiffness) of both nonirradiated and irradiated specimens were measured with the BioTester 5000 in the uniaxial mode at a strain of 10% and analyzed statistically. Individual specimens excised from 2 cadavers were also examined by routine histopathologic protocols to assess the effect of radiation on the Meibomian glands and collagen organization.</p><p><strong>Results: </strong>The irradiation enhanced both stiffness and strength of the human tarsal specimens, the difference between the test samples and controls being statistically significant ( p < 0.0002 for n = 13). Histology indicated no damage to tarsal connective tissue or to Meibomian glands, and revealed a more compact packing of the collagen network located around the glands, which may be beneficial. The existence of collagen compaction was also supported by the reduction of samples' thickness after irradiation ( p = 0.0645).</p><p><strong>Conclusions: </strong>The irradiation of tarsal tissue with ultraviolet-A light of tarsus appears to be a safe and effective method for reducing eyelid laxity in human patients.</p>","PeriodicalId":19588,"journal":{"name":"Ophthalmic Plastic and Reconstructive Surgery","volume":" ","pages":"28-35"},"PeriodicalIF":1.2,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140899322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Two-year Outcomes of Ultra-low-dose Radiotherapy in the Treatment of Ocular Adnexal B-cell Lymphomas. 超低剂量放疗治疗眼部附件B细胞淋巴瘤的两年疗效。
IF 1.2 4区 医学
Ophthalmic Plastic and Reconstructive Surgery Pub Date : 2025-01-01 Epub Date: 2024-08-19 DOI: 10.1097/IOP.0000000000002747
Alexandra I Manta, David J Schlect, Delia D Wang, Timothy J Sullivan
{"title":"Two-year Outcomes of Ultra-low-dose Radiotherapy in the Treatment of Ocular Adnexal B-cell Lymphomas.","authors":"Alexandra I Manta, David J Schlect, Delia D Wang, Timothy J Sullivan","doi":"10.1097/IOP.0000000000002747","DOIUrl":"10.1097/IOP.0000000000002747","url":null,"abstract":"<p><strong>Background: </strong>This study focuses on the efficacy and 2-year outcomes of ultra-low-dose radiotherapy (RT) in treating primary and secondary ocular adnexal lymphoma (OAL).</p><p><strong>Methods: </strong>A retrospective analysis was conducted on patients with OAL between 2017 and 2022, treated with 4 Gy of RT. The primary and secondary outcomes assessed were response rate, progression-free survival, and lymphoma-related death.</p><p><strong>Results: </strong>Twenty-one patients with primary and secondary OAL of diverse, presentations, subtypes, and stages were included. The orbital tumors had an average size of 17 × 16 × 16 mm. Of the 14 primary OAL cases, 3 (14%) had T1N0M0 disease, 8 (38%) T2N0M0, and 3 (14%) T3N0M0 (AJCC 8th edition staging); of the 7 secondary OALs, 4 (19%) were stage IE, 2 (10%) stage IIE, and 1 (5%) stage IIIE (Ann Arbor staging). Ultra-low-dose RT yielded a 95% complete response rate and 100% progression-free survival rates, both locally and systemically at 2 years. Mild dry eyes were reported in 14% of patients as a late treatment toxicity.</p><p><strong>Conclusions: </strong>Ultra-low-dose RT emerges as an effective and well-tolerated treatment approach for OAL. Our findings support the use of 4 Gy, showcasing high complete response rates (95%) and durable disease control without significant local relapses over an average follow up of 27 months. Our results align with earlier investigations, validating the curative potential of ultra-low-dose RT and reinforcing the concept of achieving favorable outcomes with minimal intervention. This approach may potentially alleviate the burden of long-term ocular side effects associated with higher radiation doses, enhancing the overall quality of life for OAL patients.</p>","PeriodicalId":19588,"journal":{"name":"Ophthalmic Plastic and Reconstructive Surgery","volume":" ","pages":"94-100"},"PeriodicalIF":1.2,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142000484","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Numerical Aberrations of the Extraocular Muscles and the Levator Palpebrae Superioris: An Anatomical and Clinical Insight. 眼外肌和上睑提肌的数字畸变:解剖学和临床启示。
IF 1.2 4区 医学
Ophthalmic Plastic and Reconstructive Surgery Pub Date : 2025-01-01 Epub Date: 2024-10-10 DOI: 10.1097/IOP.0000000000002807
Hatem A Tawfik, Omar Amro El Houssieny, Jonathan J Dutton
{"title":"Numerical Aberrations of the Extraocular Muscles and the Levator Palpebrae Superioris: An Anatomical and Clinical Insight.","authors":"Hatem A Tawfik, Omar Amro El Houssieny, Jonathan J Dutton","doi":"10.1097/IOP.0000000000002807","DOIUrl":"10.1097/IOP.0000000000002807","url":null,"abstract":"<p><strong>Purpose: </strong>To comprehensively review the literature about numerical aberrations of the orbital muscles of ocular motility (here referred to as extraocular muscles [EOMs]) and the levator palpebrae superioris (LPS).</p><p><strong>Methods: </strong>The authors summarize the embryologic bases and the possible etiopathogenetic causes of numerical aberrations of the EOMs and the LPS and organize these lesions into several broad categories. The clinical and radiologic diagnostic challenges are discussed.</p><p><strong>Results: </strong>Numerical aberrations of the EOMs include: 1) the complete absence of EOMs, 2) duplication of an entire EOM, 3) the presence of muscle bands that connect 2 EOMs, and 4) minor morphological variations such as bifid muscles (partial splitting of the muscle). Some cases may defy categorization into any of the above or may resemble atavistic remnants of the retractor bulbi muscle. Broadly speaking, numerical aberrations of the LPS generally fall into the same categories although the LPS has several peculiar numerical anomalies of its own.</p><p><strong>Conclusions: </strong>Although numerical EOM and LPS variations are relatively rare and of little clinical significance, raising awareness about their presence is a fundamental clinical keystone not just for the strabismus surgeon but for the orbital surgeon as well. During orbital surgery, this may spare the surgeon from pursuing an orbital witch hunt for these benign innocuous accessory orbital structures that were accidentally discovered by the radiologist and misinterpreted as sinister etiologies. For the strabismus surgeon, the failure to identify them may result in an unfavorable surgical outcome if these structures are missed because of a lack of awareness despite being responsible for generating complex strabismus patterns or having a restrictive potential of their own.</p>","PeriodicalId":19588,"journal":{"name":"Ophthalmic Plastic and Reconstructive Surgery","volume":" ","pages":"8-21"},"PeriodicalIF":1.2,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142471636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of Teprotumumab on Eyelid Retraction in Thyroid Eye Disease. 泰普单抗对甲状腺眼病患者眼睑后缩的影响
IF 1.2 4区 医学
Ophthalmic Plastic and Reconstructive Surgery Pub Date : 2025-01-01 Epub Date: 2024-05-09 DOI: 10.1097/IOP.0000000000002707
Eman M Al-Sharif, Jason Zhou, Marissa K Shoji, Kaela Acuff, Catherine Y Liu, Bobby S Korn, Don O Kikkawa
{"title":"Effects of Teprotumumab on Eyelid Retraction in Thyroid Eye Disease.","authors":"Eman M Al-Sharif, Jason Zhou, Marissa K Shoji, Kaela Acuff, Catherine Y Liu, Bobby S Korn, Don O Kikkawa","doi":"10.1097/IOP.0000000000002707","DOIUrl":"10.1097/IOP.0000000000002707","url":null,"abstract":"<p><strong>Purpose: </strong>This study evaluates the efficacy of teprotumumab in reducing eyelid retraction in thyroid eye disease (TED) patients.</p><p><strong>Methods: </strong>This retrospective study included patients with active or chronic moderate-to-severe TED who completed at least 4 cycles of teprotumumab. Patients with upper and/or lower eyelid retraction, defined as margin-to-reflex distance (MRD) 1 and/or MRD2 of more than 5 mm, in one or OU were included. The main outcome measure was a change in MRD1 and MRD2 after treatment. Changes in MRD1 and MRD2 were each analyzed for correlation (r) with changes in exophthalmolmetry. Student t test was performed for each comparison, and p values <0.05 were considered significant.</p><p><strong>Results: </strong>The study included 91 patients, predominantly female (87%), with an average age of 52.02 ± 14.6 years. The mean baseline proptosis measurement was 21.8 ± 2.9 OD and 21.7 ± 3.3 OS. The average MRD1 was 5.5 ± 1.5 OD and 5.4 ± 1.7 OS, and the average MRD2 was 6.1 ± 1.1 OD and 6.2 ± 1.1 OS. The follow-up duration post-treatment was 37.5 ± 31.7 weeks. At first follow-up post-treatment, the mean change in proptosis, MRD1, and MRD2 were -2.6 ± 2.0 OD, -2.5 ± 2.1 OS, -0.8.5 ± 1.4 OD, -0.8 ± 1.0 OS, and -0.7 ± 0.9 OD, -0.8 ± 1.0 OS, respectively. Correlation analysis showed that proptosis reduction was positively correlated with MRD1 and MRD2 reduction at the first post-treatment follow-up (MRD1: r = 0.23, p value < 0.01; MRD2: r = 0.17, p = 0.03].</p><p><strong>Conclusion: </strong>Teprotumumab treatment improves upper and lower eyelid retraction. The improvement in MRD correlated positively with proptosis reduction, indicating the influence of globe position on eyelid position.</p>","PeriodicalId":19588,"journal":{"name":"Ophthalmic Plastic and Reconstructive Surgery","volume":" ","pages":"22-27"},"PeriodicalIF":1.2,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140899299","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ocular Adverse Effects of Over-the-Counter Cosmetics and Personal Care Products Reported to the Food and Drug Administration. 向食品药品管理局报告的非处方化妆品和个人护理产品对眼睛的不良影响。
IF 1.2 4区 医学
Ophthalmic Plastic and Reconstructive Surgery Pub Date : 2025-01-01 Epub Date: 2024-08-13 DOI: 10.1097/IOP.0000000000002718
Aretha Zhu, Owais M Aftab, Jasmine Mahajan, Cat N Burkat
{"title":"Ocular Adverse Effects of Over-the-Counter Cosmetics and Personal Care Products Reported to the Food and Drug Administration.","authors":"Aretha Zhu, Owais M Aftab, Jasmine Mahajan, Cat N Burkat","doi":"10.1097/IOP.0000000000002718","DOIUrl":"10.1097/IOP.0000000000002718","url":null,"abstract":"<p><strong>Purpose: </strong>Personal care and cosmetic products can cause periocular and ocular adverse effects (AEs), for example, ocular surface disease, trauma, and hypersensitivity. The publicly available Food and Drug Administration (FDA) Center for Food Safety and Applied Nutrition Adverse Event Reporting System (CAERS) database includes AE reports by consumers, healthcare practitioners, and manufacturers. The purpose of this study was to characterize ophthalmic AE associated with cosmetics and personal care products reported by the FDA CAERS database.</p><p><strong>Methods: </strong>AE related to the eye or ocular adnexa from cosmetics submitted by consumers, healthcare practitioners, and manufacturers from January 2004 to June 2022 were identified after filtering using the Medical Dictionary for Regulatory Activities coding system. Demographic information, case outcome, and categories of product and AE were included. Chi-square analysis, with statistical significance at a = 0.05, was performed to ascertain variation in ocular, periocular, and general outcomes by product category.</p><p><strong>Results: </strong>Reports of ophthalmic AEs related to cosmetics per year increased from 2006 to 2018, reaching a maximum of 161 reports in 2018, then decreased from 2018 to 2021. In total, 959 and 1382 unique periocular and ocular AEs were reported. There were 1711 total incidences of reported periocular AEs and 2485 ocular AEs. The most reported periocular AEs were inflammation (770/1711) and hypersensitivity (331/1711). The most reported ocular effects were discomfort (946/2485) and inflammation (709/2485). Ocular, periocular, and general outcomes significantly varied by product category.</p><p><strong>Conclusions: </strong>Consumers, healthcare practitioners, and manufacturers should be made aware of potential ophthalmic AE and outcomes associated with cosmetics and personal care products.</p>","PeriodicalId":19588,"journal":{"name":"Ophthalmic Plastic and Reconstructive Surgery","volume":" ","pages":"61-66"},"PeriodicalIF":1.2,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141971553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Algorithmic Role of Critical Radiographic Features in the Treatment of Angioinvasive Fungal Sinusitis. 关键影像学特征在血管侵袭性真菌性鼻窦炎治疗中的算法作用》(The Algorithmic Role of Critical Radiographic Features in the Treatment of Angioinvasive Fungal Sinusitis)。
IF 1.2 4区 医学
Ophthalmic Plastic and Reconstructive Surgery Pub Date : 2025-01-01 Epub Date: 2024-09-06 DOI: 10.1097/IOP.0000000000002783
Alexis Kassotis, Allison Coombs, Nahill Matari, Angela Lignelli, Michael Kazim
{"title":"The Algorithmic Role of Critical Radiographic Features in the Treatment of Angioinvasive Fungal Sinusitis.","authors":"Alexis Kassotis, Allison Coombs, Nahill Matari, Angela Lignelli, Michael Kazim","doi":"10.1097/IOP.0000000000002783","DOIUrl":"10.1097/IOP.0000000000002783","url":null,"abstract":"<p><strong>Introduction: </strong>Angioinvasive fungal sinusitis (AIFS) is a rapidly progressive, highly morbid infection. It can be challenging to obtain an early diagnosis, but intervention in the acute period is crucial for prognosis. Previous literature has identified numerous radiographic features with high sensitivity and specificity for AIFS, even in early disease. Bedside nasal endoscopy can substantiate the diagnosis but can also yield false negative results. Initially, these patients may present to the ophthalmologist. Thus, to avoid visual and potentially life-threatening complications, subtle clinical signs in conjunction with suspicious radiographic features must be promptly recognized by the ophthalmologist and escalated appropriately. We review, for the benefit of the ophthalmic community, the salient radiographic features of AIFS and integrate them into a decision-making algorithm for diagnostic workup and management.</p><p><strong>Methods: </strong>A literature search was conducted using a comprehensive keyword search in the Pubmed and Embase databases. English studies from 1988 to 2022 describing the radiographic features of AIFS queried. Literature on the newly described entity, COVID-19 COVID-19-associated mucormycosis was included. The authors collected the most frequently reported indicators of AIFS.</p><p><strong>Results: </strong>The authors review 4 radiographic findings that are frequently associated with AIFS, including in the early stages of disease: 1) loss of contrast enhancement in the nasal turbinate and maxilla (i.e., \"black turbinate and maxillary sign\"), (2) periantral involvement seen as changes in density, fat stranding or obliteration of the anterior, retromaxillary, or retroantral fat planes on CT, (3) Tissue invasion without bony erosion, (4) Hypointense T2W sinonasal secretions on MRI in the setting of acute sinusitis. The authors additionally propose an algorithm that suggests surgical exploration for patients with clinical concern for AIFS and these radiographic features, even if bedside nasal endoscopy is inconsistent with AIFS.</p><p><strong>Conclusion: </strong>The radiographic signs highlighted herein should heighten suspicion for AIFS in the appropriate clinical setting, prompting urgent surgical exploration regardless of nasal endoscopy findings.</p>","PeriodicalId":19588,"journal":{"name":"Ophthalmic Plastic and Reconstructive Surgery","volume":" ","pages":"1-7"},"PeriodicalIF":1.2,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142140706","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reply Re: "Teprotumumab for the Treatment of Recalcitrant Thyroid Eye Disease". 回复:“Teprotumumab用于治疗顽固性甲状腺眼病”。
IF 1.2 4区 医学
Ophthalmic Plastic and Reconstructive Surgery Pub Date : 2025-01-01 Epub Date: 2025-01-03 DOI: 10.1097/IOP.0000000000002875
Clara J Men, Linus Amarikwa, Brandon Pham, Connie Sears, Kevin Clauss, Bradford W Lee, Wendy W Lee, Joshua Pasol, Shoaib Ugradar, Roman Shinder, Kimberly Cockerham, Sara Wester, Raymond Douglas, Andrea Lora Kossler
{"title":"Reply Re: \"Teprotumumab for the Treatment of Recalcitrant Thyroid Eye Disease\".","authors":"Clara J Men, Linus Amarikwa, Brandon Pham, Connie Sears, Kevin Clauss, Bradford W Lee, Wendy W Lee, Joshua Pasol, Shoaib Ugradar, Roman Shinder, Kimberly Cockerham, Sara Wester, Raymond Douglas, Andrea Lora Kossler","doi":"10.1097/IOP.0000000000002875","DOIUrl":"https://doi.org/10.1097/IOP.0000000000002875","url":null,"abstract":"","PeriodicalId":19588,"journal":{"name":"Ophthalmic Plastic and Reconstructive Surgery","volume":"41 1","pages":"111-112"},"PeriodicalIF":1.2,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142927632","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mohs Micrographic Surgery With Immunohistochemistry for the Treatment of Periocular Melanoma In Situ. 利用免疫组化技术进行莫氏显微摄影手术治疗眼周原位黑色素瘤。
IF 1.2 4区 医学
Ophthalmic Plastic and Reconstructive Surgery Pub Date : 2025-01-01 Epub Date: 2024-06-17 DOI: 10.1097/IOP.0000000000002729
Kerri M McInnis-Smith, Eucabeth M Asamoah, Addison M Demer, Kannan Sharma, Caroline Y Yu, Elizabeth A Bradley, Andrea A Tooley, Lilly H Wagner
{"title":"Mohs Micrographic Surgery With Immunohistochemistry for the Treatment of Periocular Melanoma In Situ.","authors":"Kerri M McInnis-Smith, Eucabeth M Asamoah, Addison M Demer, Kannan Sharma, Caroline Y Yu, Elizabeth A Bradley, Andrea A Tooley, Lilly H Wagner","doi":"10.1097/IOP.0000000000002729","DOIUrl":"10.1097/IOP.0000000000002729","url":null,"abstract":"<p><strong>Purpose: </strong>Mohs micrographic surgery with immunohistochemistry allows for same-day comprehensive margin assessment of melanoma in situ prior to subspecialty reconstruction. This study describes the oncologic and reconstructive outcomes of eyelid and periorbital melanoma in situ and identifies risk factors for complex reconstructive demands.</p><p><strong>Methods: </strong>Retrospective case series of all patients treated with Mohs micrographic surgery with immunohistochemistry for melanoma in situ affecting the eyelids or periorbital region from 2008 to 2018 at a single institution. Tumors were assigned to the eyelid group if the clinically visible tumor involved the skin inside the orbital rim. Reconstructive variables were compared between the eyelid and periorbital cohorts.</p><p><strong>Results: </strong>There were 24 eyelid and 141 periorbital tumors included. The initial surgical margin for all tumors was 5.34 ± 1.54 mm and multiple Mohs stages were required in 24.2% of cases. Eyelid tumors included more recurrences ( p = 0.003), and the average defect size was larger (14.0 ± 13.3 cm 2 vs. 7.7 ± 5.4 cm 2 , p = 0.03). Risk factors for complex reconstruction included: initial tumor diameter >2 cm (odds ratio [OR]: 3.84, 95% confidence interval [CI]: 1.95-7.57) and eyelid involved by initial tumor (OR: 4.88, 95% CI: 1.94-12.28). At an average follow-up of 4.8 years, there were no melanoma-related deaths and 1 local recurrence (0.6% recurrence rate).</p><p><strong>Conclusions: </strong>Mohs micrographic surgery with immunohistochemistry achieves excellent local control rates for periocular melanoma in situ. An initial surgical margin of 5 mm is frequently insufficient to achieve clear margins. The resulting defects are large, and the complexity of reconstruction can be predicted by tumor size and clinical involvement of eyelid skin.</p>","PeriodicalId":19588,"journal":{"name":"Ophthalmic Plastic and Reconstructive Surgery","volume":" ","pages":"78-83"},"PeriodicalIF":1.2,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141331530","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lateral Globe Exposure Associated With Graves Upper Eyelid Retraction: The Influence of the Superior Complex Enlargement and Proptosis. 与巴塞杜氏上眼睑后缩相关的眼球外侧暴露:上睑下垂和上睑下垂复合体扩大的影响
IF 1.2 4区 医学
Ophthalmic Plastic and Reconstructive Surgery Pub Date : 2025-01-01 Epub Date: 2024-07-16 DOI: 10.1097/IOP.0000000000002712
Juliana Guimarães, Denny M Garcia, Antonio Augusto V Cruz
{"title":"Lateral Globe Exposure Associated With Graves Upper Eyelid Retraction: The Influence of the Superior Complex Enlargement and Proptosis.","authors":"Juliana Guimarães, Denny M Garcia, Antonio Augusto V Cruz","doi":"10.1097/IOP.0000000000002712","DOIUrl":"10.1097/IOP.0000000000002712","url":null,"abstract":"<p><strong>Purpose: </strong>To investigate the association of the lateral exposure of the globe with proptosis and the enlargement of the superior complex (SC) (levator palpebrae superioris muscle + superior rectus muscle) in patients with Graves upper eyelid retraction.</p><p><strong>Methods: </strong>Twenty-eight patients with upper lid retraction secondary to Graves orbitopathy and 28 controls matched by age and gender participated in the study. The variables exophthalmometry, margin-reflex distance 1, and upper lid fissure temporal and nasal areas were assessed. Coronal CT scans were evaluated for the measurement of the SC area. A 5% level of significance was assumed for analysis.</p><p><strong>Results: </strong>Abnormal temporal nasal area differences (T-N), defined as values above the superior limit of the control distribution (15.58 mm 2 ) were detected in 18 patients. Multiple regression analysis showed a significant correlation of abnormal temporo-nasal asymmetries with the SC area and the proptosis (T-N = -6.7 + 0.62* proptosis + 12.3 SC area, R2 = 0.37; p = 0.003).</p><p><strong>Conclusion: </strong>The etiology of the enhanced lateral globe exposure is not unifactorial. SC enlargement and, to a lesser extent, proptosis are important factors correlated to lateral globe exposure.</p>","PeriodicalId":19588,"journal":{"name":"Ophthalmic Plastic and Reconstructive Surgery","volume":" ","pages":"49-51"},"PeriodicalIF":1.2,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141627278","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Necrotizing Fasciitis of the Orbit Managed With Temporary Indwelling Retrobulbar Catheter. 使用临时留置视网膜导管治疗眼眶坏死性筋膜炎
IF 1.2 4区 医学
Ophthalmic Plastic and Reconstructive Surgery Pub Date : 2025-01-01 Epub Date: 2024-10-10 DOI: 10.1097/IOP.0000000000002806
Sruti S Rachapudi, Haochen Xu, Sruti S Akella
{"title":"Necrotizing Fasciitis of the Orbit Managed With Temporary Indwelling Retrobulbar Catheter.","authors":"Sruti S Rachapudi, Haochen Xu, Sruti S Akella","doi":"10.1097/IOP.0000000000002806","DOIUrl":"10.1097/IOP.0000000000002806","url":null,"abstract":"<p><p>Necrotizing fasciitis is a rapidly progressive soft tissue infection with high mortality. Aggressive and often repeated surgical debridements are considered the mainstay of treatment, but these interventions may cause significant postoperative morbidity. In this article, the authors present a rare case of orbital necrotizing fasciitis, which was treated with the use of a temporary indwelling retrobulbar drain for antibiotic delivery to deep orbital tissues, in lieu of aggressive debridement. To the authors' knowledge, this is the first report of this technique.</p>","PeriodicalId":19588,"journal":{"name":"Ophthalmic Plastic and Reconstructive Surgery","volume":" ","pages":"e30-e32"},"PeriodicalIF":1.2,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142740187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信