Oncology nursing forum最新文献_第2页

Attachment Style and Depression in Colorectal Cancer Survivors: Mediating and Moderating Effects of Symptom Distress and Mindfulness. 结直肠癌幸存者的依恋类型与抑郁：症状困扰和正念的中介和调节作用。

IF 1.7 4区医学

Oncology nursing forum Pub Date : 2026-08-25 DOI: 10.1188/26.ONF.e26535370

Li-Ting Chen, Chih-Tao Cheng, I-Ping Huang, Jen-Ho Chang, Nien-Tzu Chang, Fei-Hsiu Hsiao

{"title":"Attachment Style and Depression in Colorectal Cancer Survivors: Mediating and Moderating Effects of Symptom Distress and Mindfulness.","authors":"Li-Ting Chen, Chih-Tao Cheng, I-Ping Huang, Jen-Ho Chang, Nien-Tzu Chang, Fei-Hsiu Hsiao","doi":"10.1188/26.ONF.e26535370","DOIUrl":"10.1188/26.ONF.e26535370","url":null,"abstract":"Objectives: To examine the relationships among adult attachment styles, symptom distress, and depressive symptoms in colorectal cancer (CRC) survivors, and to explore whether mindfulness moderates these associations.Sample and setting: A cross-sectional study was conducted with 90 CRC survivors aged 20 years or older who had completed treatment within the past three months at a medical center in northern Taiwan.Methods and variables: Participants completed validated questionnaires measuring depressive symptoms (Beck Depression Inventory-II [BDI-II]), attachment style (Experience in Close Relationships Scale-Short Form), mindfulness (Five Facet Mindfulness Questionnaire), and CRC-specific symptom distress (European Organisation for Research and Treatment of Cancer Quality-of-Life Questionnaire-CRC Module). Data were analyzed using descriptive statistics, Pearson correlations, hierarchical regression, and the Hayes PROCESS macro.Results: The mean BDI-II score was 4.96; 8% reported clinically significant depressive symptoms. Anxious attachment correlated with depression (r = 0.4, p < 0.001) and predicted depression in the initial regression model (beta = 0.5, p < 0.001). Avoidant attachment had an indirect effect through symptom distress (beta = 0.32, p = 0.002). Mindfulness moderated the anxious attachment-depression association (ΔR² = 0.03, p = 0.007), and acting with awareness moderated the avoidant attachment-depression association (ΔR² = 0.02, p = 0.02).Implications for nursing: Findings suggest that routine assessment of attachment style and mindfulness traits may help identify CRC survivors at psychological risk. Incorporating mindfulness-based education into survivorship care may support emotional well-being.","PeriodicalId":19549,"journal":{"name":"Oncology nursing forum","volume":"53 5","pages":"1-11"},"PeriodicalIF":1.7,"publicationDate":"2026-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13553028/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148888365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impact of Exercise on QOL, Cardiorespiratory Function, and Inflammatory Markers in Breast Cancer Survivors: A Systematic Review and Meta-Analysis. 运动对乳腺癌幸存者生活质量、心肺功能和炎症标志物的影响：一项系统综述和荟萃分析

IF 1.7 4区医学

Oncology nursing forum Pub Date : 2026-08-25 DOI: 10.1188/26.ONF.e26535371

Wenwen Chen, Mingying Wei, Lijuan Zhang, Yan Song

{"title":"Impact of Exercise on QOL, Cardiorespiratory Function, and Inflammatory Markers in Breast Cancer Survivors: A Systematic Review and Meta-Analysis.","authors":"Wenwen Chen, Mingying Wei, Lijuan Zhang, Yan Song","doi":"10.1188/26.ONF.e26535371","DOIUrl":"10.1188/26.ONF.e26535371","url":null,"abstract":"Problem identification: Breast cancer is the most common cancer type in women globally. Although survival rates have improved, treatments cause lasting issues, including impaired cardiorespiratory fitness, chronic inflammation, and reduced quality of life (QOL). Exercise is recommended to alleviate these burdens, but evidence remains inconsistent regarding its effects on cardiorespiratory function, inflammatory markers, and QOL, with limited integrated evaluation.Literature search: A systematic search was conducted in the Cochrane Central Register of Controlled Trials, Embase®, PubMed®, and Web of Science for articles published from database inception to April 15, 2025.Data evaluation: The systematic review contained 32 studies involving 1,754 survivors. Literature quality was assessed using the Cochrane Risk of bias assessment tool 2, with analyses performed using RevMan, version 5.4, and Stata, version 18.0.Synthesis: Exercise significantly improved peak oxygen consumption (weighted mean difference [WMD] = 1.22, p < 0.001) and QOL (general: WMD = 6.05, p < 0.001; breast cancer-specific: WMD = 5.13, p = 0.045). No significant effects were found on maximum oxygen consumption, C-reactive protein, interleukin-6, or tumor necrosis factor-alpha (p > 0.05).Implications for practice: Clinical practice should routinely recommend exercise to improve cardiopulmonary fitness and QOL in breast cancer survivors. Clinicians should incorporate exercise into rehabilitation plans and encourage participation, and future research should explore its specific effects on inflammatory markers.","PeriodicalId":19549,"journal":{"name":"Oncology nursing forum","volume":"53 5","pages":"1-17"},"PeriodicalIF":1.7,"publicationDate":"2026-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13553033/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148888360","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cape On: Protecting Nursing Science. Cape On：保护护理科学。

IF 1.7 4区医学

Oncology nursing forum Pub Date : 2026-08-25 DOI: 10.1188/26.ONF.e26535366

Janine Overcash

引用次数: 0

Caregivers' Perspectives on Cancer-Related Cognitive Impairment in Older Adults With Acute Myeloid Leukemia Receiving Chemotherapy. 护理者对接受化疗的老年急性髓性白血病患者癌症相关认知障碍的看法

IF 1.7 4区医学

Oncology nursing forum Pub Date : 2026-06-24 DOI: 10.1188/26.ONF.e26535331

Ya-Ning Chan, Youngmin Cho, Rachel Hirschey, Aaron Piepmeier, Catherine M Bender, Ruth A Anderson, Matthew C Foster, Ashley Leak Bryant

{"title":"Caregivers' Perspectives on Cancer-Related Cognitive Impairment in Older Adults With Acute Myeloid Leukemia Receiving Chemotherapy.","authors":"Ya-Ning Chan, Youngmin Cho, Rachel Hirschey, Aaron Piepmeier, Catherine M Bender, Ruth A Anderson, Matthew C Foster, Ashley Leak Bryant","doi":"10.1188/26.ONF.e26535331","DOIUrl":"10.1188/26.ONF.e26535331","url":null,"abstract":"Purpose: To explore caregivers' perspectives on cancer-related cognitive impairment (CRCI) experiences in older adults with acute myeloid leukemia receiving chemotherapy.Participants & setting: Eight caregivers, including adult children and spouses, of older adults with acute myeloid leukemia receiving chemotherapy from the control arm of a clinical trial were interviewed.Methodologic approach: Semistructured interviews were conducted at the second, fourth, and seventh cycles of chemotherapy. All interviews were audio recorded and transcribed verbatim. Two researchers independently analyzed 16 transcripts using thematic analysis.Findings: Four themes were identified: (a) CRCI experiences, (b) impact of CRCI, (c) CRCI coping strategies, and (d) perceived CRCI-related factors. Caregivers observed changes in memory, concentration, and information processing in their loved ones and developed various strategies to better support or cope with CRCI. In addition, CRCI influenced caregivers' emotions, lives, and relationships with their loved ones.Implications for nursing: Caregivers of older adults with acute myeloid leukemia play a vital role in CRCI symptom monitoring. The impact of CRCI on caregivers highlights the importance of supporting caregivers, and the identified coping strategies can provide guidance for future intervention development.","PeriodicalId":19549,"journal":{"name":"Oncology nursing forum","volume":"53 4","pages":"1-9"},"PeriodicalIF":1.7,"publicationDate":"2026-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13309158/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148318320","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Patient Experience of Preirradiation Dental Screening Prior to Radiation Therapy for Head and Neck Cancer. 头颈癌放射治疗前的放射前牙科筛查患者经验。

IF 1.7 4区医学

Oncology nursing forum Pub Date : 2026-06-24 DOI: 10.1188/26.ONF.e26535332

Annemette Deisner, Camilla Bille Nielsen, Ann-Mari Singers Johansen, Charlotte Nielsen, Lone Forner

{"title":"Patient Experience of Preirradiation Dental Screening Prior to Radiation Therapy for Head and Neck Cancer.","authors":"Annemette Deisner, Camilla Bille Nielsen, Ann-Mari Singers Johansen, Charlotte Nielsen, Lone Forner","doi":"10.1188/26.ONF.e26535332","DOIUrl":"10.1188/26.ONF.e26535332","url":null,"abstract":"Purpose: To explore the preirradiation dental screening experiences of patients with head and neck cancer and how this understanding can contribute to the enhancement of nursing practice.Participants & setting: In 2022 and 2023, patients diagnosed with head and neck cancer with planned radiation therapy were recruited. The study was conducted at a university hospital in Denmark, where preirradiation dental screening is an integrated component of the fast-track cancer pathway.Methodologic approach: A qualitative, phenomenologic-hermeneutic design was applied, employing semistructured telephone interviews with 10 patients. Detailed field notes were used to construct individual patient narratives. Data were analyzed using reflexive thematic analysis to capture the depth and variation in patients' lived experiences.Findings: Four main themes were identified: anxiety for the future and the dentist, information overload, the stressful day, and confidence in efficiency. Overall, patient experiences clustered into two overarching patterns: compromised course and successful course.Implications for nursing: Patients' experiences vary widely. Anxiety, information overload, and stressful logistics may compromise the patient's experience, whereas clear information and supportive interactions may result in confidence. It is recommended that nursing practice prioritize individual support using Henderson's model, ensuring that needs are addressed and managing information overload throughout the complex treatment process of preirradiation dental screening.","PeriodicalId":19549,"journal":{"name":"Oncology nursing forum","volume":"53 4","pages":"1-10"},"PeriodicalIF":1.7,"publicationDate":"2026-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13309156/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148318402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Concordance Between Patient-Reported and Clinically Documented Symptoms in Acute Myeloid Leukemia. 急性髓系白血病患者报告症状与临床记录症状的一致性

IF 1.7 4区医学

Oncology nursing forum Pub Date : 2026-06-24 DOI: 10.1188/26.ONF.e26535329

Sena Chae, Jaewon Bae, Nayung Youn, Hanh Pham, Karen Dunn Lopez, Grerk Sutamtewagul, Barbara Rakel

{"title":"Concordance Between Patient-Reported and Clinically Documented Symptoms in Acute Myeloid Leukemia.","authors":"Sena Chae, Jaewon Bae, Nayung Youn, Hanh Pham, Karen Dunn Lopez, Grerk Sutamtewagul, Barbara Rakel","doi":"10.1188/26.ONF.e26535329","DOIUrl":"10.1188/26.ONF.e26535329","url":null,"abstract":"Objectives: To describe the frequency and documentation patterns of patient-reported and clinically documented symptoms, and to determine the degree of concordance and discordance between patient-reported symptoms and electronic health record (EHR) documentation.Sample & setting: 31 adult patients with acute myeloid leukemia hospitalized at a large academic tertiary healthcare center.Methods & variables: Self-reported symptoms were collected using a modified Memorial Symptom Assessment Scale, in which patients reported symptoms experienced during the prior seven days. Clinician-documented symptoms were manually extracted from clinical notes and nursing flow sheets in the EHR. Concordance and discordance were evaluated using Cohen's kappa and McNemar's tests.Results: Lack of energy (87% patients, 87% clinicians) and lack of appetite (74% patients, 84% clinicians) were the most frequently reported symptoms. However, many symptoms, particularly psychosocial symptoms such as feeling sad (n = 17 patients, 2 clinicians; kappa = -0.01, p = 0.001) and feeling irritable (n = 10 patients, 2 clinicians; kappa = -0.12, p = 0.043), showed substantial discordance and were often underdocumented in the EHR, suggesting that subjective patient experiences may be overlooked in routine documentation.Implications for nursing: Accurate and comprehensive symptom documentation is essential for effective symptom management and clinical decision-making. Integrating structured symptom assessment tools or patient-reported outcomes into the EHR may improve documentation accuracy and enhance the quality of care for patients with acute myeloid leukemia.","PeriodicalId":19549,"journal":{"name":"Oncology nursing forum","volume":"53 4","pages":"1-13"},"PeriodicalIF":1.7,"publicationDate":"2026-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13309155/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148318338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Exploring Information Needs of Patients With Cancer and Family Caregivers: A Descriptive and Network Analysis of End-of-Life Inquiries. 探索癌症患者和家庭照护者的资讯需求：临终问询的描述与网路分析。

IF 1.7 4区医学

Oncology nursing forum Pub Date : 2026-06-24 DOI: 10.1188/26.ONF.e26535335

Virginia LeBaron, Sandra A Mitchell, Grace C Huang, Diane Ng, Janet S de Moor, Robin C Vanderpool

{"title":"Exploring Information Needs of Patients With Cancer and Family Caregivers: A Descriptive and Network Analysis of End-of-Life Inquiries.","authors":"Virginia LeBaron, Sandra A Mitchell, Grace C Huang, Diane Ng, Janet S de Moor, Robin C Vanderpool","doi":"10.1188/26.ONF.e26535335","DOIUrl":"10.1188/26.ONF.e26535335","url":null,"abstract":"Objectives: To characterize patient and caregiver end-of-life (EOL) information needs through analysis of inquiries received by the National Cancer Institute's Cancer Information Service (CIS).Sample & setting: The sample consisted of CIS inquiries received between September 2018 and June 2024 that were (a) initiated by patients or caregivers and (b) coded as focusing on the EOL phase of the cancer continuum.Methods & variables: Descriptive and network analyses were conducted to characterize CIS inquiries and explore patterns of co-occurrence related to subjects of inquiry.Results: Of the 81,836 inquiries received by the CIS during the study period, 3% (n = 2,333) focused on EOL; of these, 90% were initiated by caregivers. Patterns of subject-of-inquiry co-occurrence related to palliative care/hospice, finding healthcare services, cancer-directed therapies, coping, and clinical trials were observed. Patient and caregiver network structures were highly correlated (r = 0.799, p < 0.001), suggesting similar patterns of information needs.Implications for nursing: Tailoring informational support and bundling common information needs are crucial strategies to optimally support patients with cancer and caregivers at the EOL. These findings highlight the need for nurse-led, novel care delivery models that can address unmet needs and improve the provision of support, such as caregiver-focused, community-based navigation; delivery of palliative care concurrent with cancer-directed therapies; and embedded caregiver clinics within cancer centers.","PeriodicalId":19549,"journal":{"name":"Oncology nursing forum","volume":"53 4","pages":"1-13"},"PeriodicalIF":1.7,"publicationDate":"2026-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13309161/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148318409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Postoperative Physiologic Comfort Management for Patients With Hepatocellular Carcinoma Undergoing Hepatic Arterial Infusion Chemotherapy. 肝癌肝动脉输注化疗患者术后生理舒适管理。

IF 1.7 4区医学

Oncology nursing forum Pub Date : 2026-06-24 DOI: 10.1188/26.ONF.e26535330

Rui Yuan, Xiangqian Kong, Yongjiao Kang, Fengying He

{"title":"Postoperative Physiologic Comfort Management for Patients With Hepatocellular Carcinoma Undergoing Hepatic Arterial Infusion Chemotherapy.","authors":"Rui Yuan, Xiangqian Kong, Yongjiao Kang, Fengying He","doi":"10.1188/26.ONF.e26535330","DOIUrl":"10.1188/26.ONF.e26535330","url":null,"abstract":"Problem identification: Postoperative comfort management for patients with hepatocellular carcinoma undergoing hepatic arterial infusion chemotherapy remains unstandardized, with fragmented evidence limiting clinical practice.Literature search: To establish China's first evidence-based framework for postoperative physiologic comfort management in patients with hepatocellular carcinoma undergoing hepatic arterial infusion chemotherapy, a systematic evidence synthesis, guided by the 6S Pyramid, was conducted. Sixteen databases, including PubMed®, Cochrane Library, and CNKI, were searched from inception to July 2024.Data evaluation: Literature was systematically retrieved, appraised, and synthesized. Two researchers independently assessed study quality using AGREE II (Appraisal of Guidelines for Research and Evaluation) and JBI tools. Evidence extraction followed hierarchical principles, with conflicts resolved through panel arbitration.Synthesis: 14 studies were included, yielding 13 recommendations across the following six domains: patient education, nausea and vomiting control, gastrointestinal recovery, pain management, urinary retention, and early mobilization.Implications for practice: The proposed postoperative physiologic comfort management framework enables standardized nursing protocols across hospital settings, prioritizes patient-centered outcomes, and establishes measurable comfort metrics. Nurses can implement structured preoperative education and functional training while adopting stratified symptom management for patients undergoing hepatic arterial infusion chemotherapy.","PeriodicalId":19549,"journal":{"name":"Oncology nursing forum","volume":"53 4","pages":"1-14"},"PeriodicalIF":1.7,"publicationDate":"2026-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13309163/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148318457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Seven-Year Cognitive Trajectories in Older Adult Cancer Survivors: Findings From a National Cohort Study. 老年癌症幸存者的7年认知轨迹：来自一项国家队列研究的发现。

IF 1.7 4区医学

Oncology nursing forum Pub Date : 2026-06-24 DOI: 10.1188/26.ONF.e26535336

Junlan Pu, Wei Luo, Youmin Cho, Weijiao Zhou

{"title":"Seven-Year Cognitive Trajectories in Older Adult Cancer Survivors: Findings From a National Cohort Study.","authors":"Junlan Pu, Wei Luo, Youmin Cho, Weijiao Zhou","doi":"10.1188/26.ONF.e26535336","DOIUrl":"10.1188/26.ONF.e26535336","url":null,"abstract":"Objectives: To describe the long-term trajectories of cognitive impairment in older adult cancer survivors and to identify factors associated with distinct trajectories.Sample & setting: Data were sourced from the National Health and Aging Trends Study (2015-2021), a nationally representative cohort study of community-dwelling older adults aged 65 years or older.Methods & variables: Cognitive function was assessed annually with self-reported diagnoses and cognitive function tests. Group-based trajectory models were used to identify cognitive trajectories, and multinomial logistic regression models were used to examine associations between baseline characteristics and trajectory affiliations.Results: 1,564 older adults with cancer and 3,447 without cancer were included. Four trajectories of cognitive impairment were identified: low-stable (64%), low-slowly deteriorating (18%), low-rapidly deteriorating (6%), and persistent-high (12%). Older age, lower education and income levels, poorer self-rated health, physical frailty, and comorbidities were significantly associated with persistent-high or deteriorating trajectories (p < 0.05).Implications for nursing: The current study highlights the specific dynamic features of cognitive decline among older adult cancer survivors and identifies risk factors for early identification of patients at high risk for less favorable trajectories.","PeriodicalId":19549,"journal":{"name":"Oncology nursing forum","volume":"53 4","pages":"1-10"},"PeriodicalIF":1.7,"publicationDate":"2026-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13309162/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148318405","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Impact of Side Effects on Oral Anticancer Agent Self-Management: Patient Perception of Risks Matters. 副作用对口服抗癌药物自我管理的影响：患者对风险的认知问题。

IF 1.7 4区医学

Oncology nursing forum Pub Date : 2026-06-24 DOI: 10.1188/26.ONF.e26535328

Yupawadee Kantabanlang, Misun Hwang, John C Krauss, Heidi Mason, Yun Jiang

{"title":"The Impact of Side Effects on Oral Anticancer Agent Self-Management: Patient Perception of Risks Matters.","authors":"Yupawadee Kantabanlang, Misun Hwang, John C Krauss, Heidi Mason, Yun Jiang","doi":"10.1188/26.ONF.e26535328","DOIUrl":"10.1188/26.ONF.e26535328","url":null,"abstract":"Objectives: To examine the relationship between side effect severity and self-management ability in patients taking capecitabine and investigate whether medication beliefs mediate this relationship.Sample & setting: A secondary analysis was conducted using data from a descriptive study of 50 patients with gastrointestinal cancer receiving capecitabine at the University of Michigan Rogel Cancer Center.Methods & variables: Self-management ability was assessed using the Measure of Drug Self-Management. The severity of capecitabine-related side effects was measured using the Patient-Reported Outcomes version of the Common Terminology Criteria for Adverse Events. Patients' perceived necessity of and concerns about capecitabine were evaluated using the Beliefs about Medicines Questionnaire (adapted for capecitabine). Descriptive statistics, multiple linear regression, and PROCESS macro mediation analysis were employed.Results: Self-management ability was significantly associated with total side effect severity (beta = -1.09, p = 0.003). This relationship was partially mediated by patients' overall beliefs about capecitabine (beta = -0.74, p = 0.04) and fully mediated by concerns about its potential harms (beta = -0.6, p = 0.11).Implications for nursing: Oncology nurses should adopt a patient-centered approach that includes counseling about the benefits of capecitabine, addressing concerns about adverse effects, and reinforcing patients' self-efficacy and social support networks to enhance self-management during therapy.","PeriodicalId":19549,"journal":{"name":"Oncology nursing forum","volume":"53 4","pages":"1-12"},"PeriodicalIF":1.7,"publicationDate":"2026-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13309159/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148318430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0