SAS Journal of Medicine最新文献

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Partially Alopecic Plaque of the Forearm Revealing a Familial Ringworm 前臂部分脱发斑块揭示家族癣
SAS Journal of Medicine Pub Date : 2023-08-08 DOI: 10.36347/sasjm.2023.v09i08.004
Tahri Joutei Hassani Kenza, Z. Douhi, H. Baybay, S. Elloudi, Meryem Soughi, F. Mernissi
{"title":"Partially Alopecic Plaque of the Forearm Revealing a Familial Ringworm","authors":"Tahri Joutei Hassani Kenza, Z. Douhi, H. Baybay, S. Elloudi, Meryem Soughi, F. Mernissi","doi":"10.36347/sasjm.2023.v09i08.004","DOIUrl":"https://doi.org/10.36347/sasjm.2023.v09i08.004","url":null,"abstract":"Dermatophytes are capable of infecting the skin and its appendages such as nails and hairs producing a variety of clinical conditions. Hair invasion by dermatophytes is a key feature of tinea capitis and tinea barbae but not of tinea of glabrous skin. Follicular involvement of glabrous skin is a rare entity resisting to topical treatment and should be considered for systemic antifungal treatments. We report a new observation of Tinea Folliculorom of the forearm revealing a familial ringworm.","PeriodicalId":193141,"journal":{"name":"SAS Journal of Medicine","volume":"299 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124280122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Intralenticular Metallic Foreign Body: A Case Report 球囊内金属异物1例报告
SAS Journal of Medicine Pub Date : 2023-08-06 DOI: 10.36347/sasjm.2023.v09i08.001
Maan Ali Almokdad, Ashraf Alakkad
{"title":"Intralenticular Metallic Foreign Body: A Case Report","authors":"Maan Ali Almokdad, Ashraf Alakkad","doi":"10.36347/sasjm.2023.v09i08.001","DOIUrl":"https://doi.org/10.36347/sasjm.2023.v09i08.001","url":null,"abstract":"Background: Intraocular foreign body (IOFB) injuries exhibit variations based on multiple factors, including size, composition, location, type, contamination, the extent of tissue damage, and potential complications that may arise. Case Presentation: This case study describes a 48-year-old male patient who presented to the outpatient clinic with a progressive decline in vision in the right eye lasting three weeks. The patient reported a history of redness in the affected eye, occurring for several days after performing maintenance work. Intraocular pressure measurements were normal for both eyes. The slit lamp examination revealed a corneal opacity near the limbus at the 2 o'clock position in the right eye, along with a small peripheral iris hole aligned with the corneal opacity. Additional diagnostic investigations, including a B-scan ultrasound and a CT scan of the orbit without contrast, were conducted. The B-scan ultrasound showed a clear vitreous and a flat retina, while the CT scan detected a metallic foreign body measuring 3x3 mm. The foreign body was found to be partially embedded in the lens and partially in the vitreous, as confirmed by the imaging. As a result, the patient was admitted to the hospital, and a comprehensive treatment plan was implemented. Topical antibiotics, steroids, cycloplegic, and nonsteroidal anti-inflammatory eye drops were prescribed. The patient underwent cataract surgery with sulcus intraocular lens implantation, combined with a pars plana vitrectomy to remove the foreign body. Additional procedures, such as 360 laser treatment, air-fluid exchange, and injection of SF6 gas, were performed. Conclusion: This case highlights the successful management of an intraocular foreign body injury, emphasizing the significance of prompt diagnosis and appropriate surgical intervention in achieving positive visual outcomes.","PeriodicalId":193141,"journal":{"name":"SAS Journal of Medicine","volume":"77 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125230054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Factors Responsible for Missed Opportunities of Immunization among Children 0-5 Years in Mgbundukwu Health Centre in Port Harcourt, Rivers State 河流州哈科特港Mgbundukwu保健中心0-5岁儿童错过免疫接种机会的因素
SAS Journal of Medicine Pub Date : 2023-08-06 DOI: 10.36347/sasjm.2023.v09i08.002
Alozie Stella Uloaku, Gospel Chimenma Dimkpa, J. Paul, Dumoteinm Stephen Opuda Ekine, Rita Chika-Alfred Nwokah, Idawarifa Frank Cookey- Gam, Kingsley Moses Amadi, Gloria Stanley Acra Jones
{"title":"Factors Responsible for Missed Opportunities of Immunization among Children 0-5 Years in Mgbundukwu Health Centre in Port Harcourt, Rivers State","authors":"Alozie Stella Uloaku, Gospel Chimenma Dimkpa, J. Paul, Dumoteinm Stephen Opuda Ekine, Rita Chika-Alfred Nwokah, Idawarifa Frank Cookey- Gam, Kingsley Moses Amadi, Gloria Stanley Acra Jones","doi":"10.36347/sasjm.2023.v09i08.002","DOIUrl":"https://doi.org/10.36347/sasjm.2023.v09i08.002","url":null,"abstract":"Immunization over the years has been so effective that its ability to save lives of under-five children globally and more has promoted its usage all over the world especially in the developing countries. The aim of the study was to determine the factors responsible for missed opportunities of immunization among children of 0-5 years in Mgbundukwu Model Primary Health Center, Port Harcourt, Rivers State. The study was guided by four objectives and research questions. The study employed a descriptive survey design. A sample size of 120 was drawn using simple random sampling technique and data was collected using a self-developed structured questionnaire. The Standard World Health Organization, Expanded Programme on Immunization (WHO EPI) protocol was used for assessing missed opportunities for immunization. Data obtained were analyzed using frequencies and percentages. The result showed that majority of mothers (94.0%) have heard of National Programme on Immunization (NPI), mothers who had heard of immunization from the health facilities had the highest percentage of 55.0%. The result also shows an increased prevalence of missed opportunity for immunization 61(61.0%), missed opportunity for immunization was more common for OPV3 (13.33%) compared to other vaccines, the factors responsible for the missed opportunity for immunization were failure to attend antenatal care and home delivery, concern about vaccine safety, long distance trekking/walking to health center, long waiting time, lack of money, lack of vaccine at the health center when visited and lack of information about day of immunization. It was recommended that health awareness campaign targeted at caretakers on the importance of immunization should be carried out regularly and government should encourage community participation in immunization programmes.","PeriodicalId":193141,"journal":{"name":"SAS Journal of Medicine","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117120884","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Radiological Features of Zoledronic Acid Therapy in Saudi Children with Osteogenesis Imperfecta 唑来膦酸治疗沙特儿童成骨不全的影像学特点
SAS Journal of Medicine Pub Date : 2023-07-31 DOI: 10.36347/sasjm.2023.v09i07.013
Bassam Bin- Abbas, Alhanouf Al Jaser, Musaab Al Saad, Fawaz Al Shaalan, Rafah Ghazi, F. Abbas, F. Shareef, Abdullah Al Fares, Afaf Al Sagheir
{"title":"Radiological Features of Zoledronic Acid Therapy in Saudi Children with Osteogenesis Imperfecta","authors":"Bassam Bin- Abbas, Alhanouf Al Jaser, Musaab Al Saad, Fawaz Al Shaalan, Rafah Ghazi, F. Abbas, F. Shareef, Abdullah Al Fares, Afaf Al Sagheir","doi":"10.36347/sasjm.2023.v09i07.013","DOIUrl":"https://doi.org/10.36347/sasjm.2023.v09i07.013","url":null,"abstract":"Background: The majority of osteogenesis imperfecta (OI) cases have an autosomal dominant pattern of inheritance and are usually caused by mutations in genes encoding type I collagen. Patients with OI may have blue sclerae, dentinogenesis imperfecta, and growth deficiency. Zoledronic acid is a third-generation bisphosphonate which was reported to inhibit osteoclast-mediated bone resorption, improve bone density, and reduce incidence of fractures. Aim: To describe the radiographic features of cyclic Zoledronic acid administration on the growing skeleton in children with OI and to report the efficacy of Zoledronic acid on bone mineral density. Methods: We retrospectively reviewed the radiographs of 11 children treated with Zoledronic acid. The age of these children ranged from one to 13 years. Zoledronic acid was administrated intravenously at 6 months intervals at the Pediatric Endocrinology Day Medical Unit, King Faisal Specialist Hospital and Research Centre, and Security Forces Hospital, Riyadh, Kingdom of Saudi Arabia for 2 years. Results: During the course of treatment, a gradual increase in bone density was observed. The baseline mean lumbar BMDz score was -4.9SD + 1.3, which improved to a mean score of -2.7SD + 1.1, and a mean whole body BMDz score was -2SD +1.2 and improved to a mean score of -1.1SD + 1.3 by the end of therapy. Post treatment, there were multiple sclerotic metaphyseal bands seen in all children in the long bones paralleling to the growth plates and corresponding to the number of treatment cycles. Conclusion: Intravenous Zoledronic acid in children with osteogenesis imperfecta improved the bone mineral density and resulted in permanent sclerotic metaphyseal bands.","PeriodicalId":193141,"journal":{"name":"SAS Journal of Medicine","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127635636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Isolated Posterior Dislocation of the Radial Head in the Adult: An Injury not to be Missed 成人孤立性桡骨头后脱位:一种不容忽视的损伤
SAS Journal of Medicine Pub Date : 2023-07-29 DOI: 10.36347/sasjm.2023.v09i07.012
Seixas Hugo Rui Souto, Figueiredo Alfredo, Dourado Paulo
{"title":"Isolated Posterior Dislocation of the Radial Head in the Adult: An Injury not to be Missed","authors":"Seixas Hugo Rui Souto, Figueiredo Alfredo, Dourado Paulo","doi":"10.36347/sasjm.2023.v09i07.012","DOIUrl":"https://doi.org/10.36347/sasjm.2023.v09i07.012","url":null,"abstract":"Introduction: Isolated radial head dislocation in the adult is a rare and frequently missed traumatic injury. It is most commonly seen in children as a radial head subluxation. It should be diagnosed and treated without delay to avoid long-term sequelae to the joint. Case Presentation: A 22-year-old male presented to the Emergency Department complaining of persistent pain in his right elbow after a fall one week before. He had been diagnosed with an elbow sprain and arrived to our hospital using an above-elbow cast placed. The radiological evaluation revealed a posterior dislocation of the radial head without associated fractures. The patient was submitted to closed reduction followed by a cast immobilization. The follow-up weeks later showed a full and painless elbow range of motion. Discussion: Isolated posterior dislocation of the radial head in the adult is an infrequent injury, with only a few cases described in the literature. Therefore, a delay in diagnosis of a traumatic radial head dislocation in the absence of a concurrent ulnar fracture may occur. The case presented illustrates how easily the injury can be missed in the first medical evaluation. It also shows how a timely closed reduction can reestablish the joint’s full range of motion. Delay in treatment usually requires open reduction and may result in a poor functional outcome. Conclusion: A high index of suspicion is essential for the diagnosis of isolated posterior dislocation of the radial head. This clinical case demonstrated that early diagnosis and prompt treatment can successfully repair the injury and prevent functional disability of the elbow joint.","PeriodicalId":193141,"journal":{"name":"SAS Journal of Medicine","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126447209","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Acquired Postpartum Hemophilia A: About 3 Cases 产后获得性血友病A:约3例
SAS Journal of Medicine Pub Date : 2023-07-25 DOI: 10.36347/sasjm.2023.v09i07.011
Widad Rhandour, Hajar Masrour, Latifa Laaghrib, N. Oubelkacem, Z. Khammar, R. Berrady
{"title":"Acquired Postpartum Hemophilia A: About 3 Cases","authors":"Widad Rhandour, Hajar Masrour, Latifa Laaghrib, N. Oubelkacem, Z. Khammar, R. Berrady","doi":"10.36347/sasjm.2023.v09i07.011","DOIUrl":"https://doi.org/10.36347/sasjm.2023.v09i07.011","url":null,"abstract":"Introduction: Acquired hemophilia A (AHA) is a rare but severe autoimmune disorder. It is caused by the acquisition of autoantibodies to factor VIII (FVIII). These post-partum autoantibodies account for 7-21% of all cases of AHA and most often develop after the first pregnancy. We report 3 new cases of postpartum-acquired hemophilia A. Observations: Three young women with no prior pathological history presented with a spontaneous and heterogeneous hemorrhagic syndrome, two cases of deep hematomas, and haematuria with ecchymosis in the 3rd patient. The diagnosis was made in all our patients based on plasma FVIII activity <50% and the presence of an FVIII inhibitor. Immunological tests and neoplastic research were negative in all our patients. Hemostatic treatment combined with corticosteroid therapy and immunosuppressive drugs were used for the 3 patients. Conclusion: AHA is a rare disease, and its diagnosis is often underestimated in our population. It is essential to make clinicians aware of this pathology and to be able to evoke it in young patients of childbearing age. A relapse is possible in future pregnancies, so long-term follow-up is recommended.","PeriodicalId":193141,"journal":{"name":"SAS Journal of Medicine","volume":"75 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114447891","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Serum Ferritin Level as a Predictor of Disease Severity in Patients with Dengue Infection 血清铁蛋白水平作为登革热感染患者疾病严重程度的预测因子
SAS Journal of Medicine Pub Date : 2023-07-25 DOI: 10.36347/sasjm.2023.v09i07.010
Sumaiya Farah Marisa, M. Azad
{"title":"Serum Ferritin Level as a Predictor of Disease Severity in Patients with Dengue Infection","authors":"Sumaiya Farah Marisa, M. Azad","doi":"10.36347/sasjm.2023.v09i07.010","DOIUrl":"https://doi.org/10.36347/sasjm.2023.v09i07.010","url":null,"abstract":"Background: Dengue infection is a major public health threat. The clinical spectrum of dengue infection is variable from mild fever to severe forms. Early laboratory diagnosis of dengue fever is important to provide appropriate treatment to the patients and to prevent potential complications. Although there are various biomarkers to predict the severity of dengue, they are not routinely used in clinical practice for prognostication. This study evaluated the performance of serum ferritin to predict the severity of dengue at an earlier stage as it is an inexpensive and easily accessible biomarker. Methods: Total 62 patients with diagnosis of dengue fever were enrolled after final selection. Serum ferritin levels of all the patients were measured on the day of admission. Patients were then divided into two groups on the basis of ferritin level. Group A comprising those with normal level and those having raised level were included in group B. Patients were then regularly followed up both clinically and biochemically during their hospital stay to see disease progression. Discharge from the hospital without complications or death of the patient during the hospital stay was the end point of the study. Every patient was managed according to the National Guideline for Clinical Management of Dengue Syndrome. Results: Most of the respondents (58.1%) belonged to the age group of 18-30 years with male predominance (69.4%). A significant association was found between the BMI of respondents & the groups (p<0.05). Highly significant association was reported among mucosal bleed (37.1%), clinical fluid accumulation (29.0%) & liver enlargement (30.6%) with ferritin level (p<0.001). A positive correlation was found between serum ferritin & hematocrit level of the respondents (r=0.719; p<0.001) and a negative correlation was found between serum ferritin & platelet level of the respondents (r= -0.857; p<0.001), both of which were highly significant. Patients with high level of ferritin .","PeriodicalId":193141,"journal":{"name":"SAS Journal of Medicine","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131096377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Microdeletion 3q13.31 and Agenesis of the Corpus Callosum in a Patient with Intellectual Disability and Autism Spectrum Disorder: A Case Report 智力残疾和自闭症谱系障碍患者胼胝体微缺失3q13.31和发育缺失1例
SAS Journal of Medicine Pub Date : 2023-07-22 DOI: 10.36347/sasjm.2023.v09i07.009
S. Benhammou, M. Raissouni, H. Zarof, H. Kisra
{"title":"Microdeletion 3q13.31 and Agenesis of the Corpus Callosum in a Patient with Intellectual Disability and Autism Spectrum Disorder: A Case Report","authors":"S. Benhammou, M. Raissouni, H. Zarof, H. Kisra","doi":"10.36347/sasjm.2023.v09i07.009","DOIUrl":"https://doi.org/10.36347/sasjm.2023.v09i07.009","url":null,"abstract":"Total agenesis of the corpus callosum (ACC) is a rare condition characterized by the absence of corpus callosum formation during fetal development. It can occur in isolation or be associated with congenital syndromes, including the emerging microdeletion syndrome 3q13.31. This syndrome, caused by a deletion in the long arm of chromosome 3, presents with developmental delay, growth abnormalities, craniofacial dysmorphology, skeletal malformations, genital anomalies, and agenesis of the corpus callosum. The case of a 7½-year-old boy with microdeletion 3q13.31 is described, highlighting common clinical manifestations observed in this syndrome. The patient exhibited delayed psychomotor development, language delay, autism spectrum disorder, intellectual disability, facial dysmorphology, and agenesis of the corpus callosum. Comparison with existing literature showed similarities in features such as delayed development, language delays, intellectual disability, and brain anomalies. The 3q13.31 microdeletion syndrome encompasses a wide range of clinical phenotypes, and the identification of responsible genes contributes to understanding the condition, although treatment remains challenging.","PeriodicalId":193141,"journal":{"name":"SAS Journal of Medicine","volume":"42 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121709849","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dide Botcazo Syndrome: An Atypical and Rare Presentation of Stroke 迪德·波卡佐综合征:一种非典型和罕见的中风表现
SAS Journal of Medicine Pub Date : 2023-07-22 DOI: 10.36347/sasjm.2023.v09i07.008
Abdi Kadira, C. Moussavou, Houda Alloussi, A. Bakal, N. Mouloudi, H. Mohamed, Youssef Benmoh, A. Bourazza
{"title":"Dide Botcazo Syndrome: An Atypical and Rare Presentation of Stroke","authors":"Abdi Kadira, C. Moussavou, Houda Alloussi, A. Bakal, N. Mouloudi, H. Mohamed, Youssef Benmoh, A. Bourazza","doi":"10.36347/sasjm.2023.v09i07.008","DOIUrl":"https://doi.org/10.36347/sasjm.2023.v09i07.008","url":null,"abstract":"Dide-Botcazo syndrome is a very rare condition resulting from bilateral posterior cerebral infarction. The clinical presentation is atypical of cerebral infarction and is characterized by the association of cortical blindness and anosognosia associated with amnesia and topographical disorientation. We report the clinical case of a 65-year-old man consulting for confusion associated with amnesia, cortical blindness and right hemiparesis evolving for one week. The CT scan showed hypodensity in the territory of the bilateral posterior cerebral arteries. The scan also ruled out malformations such as aneurysms or cerebral masses, as well as hemorrhagic stroke. The patient was treated with antiplatelet drugs and early rehabilitation. Progression was marked by partial improvement in motor disorders and confusion. Cortical blindness and anosognosia were permanent.","PeriodicalId":193141,"journal":{"name":"SAS Journal of Medicine","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130110248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Proton Therapy for Nasopharyngeal Cancer: A Systematic Review 鼻咽癌质子治疗:系统综述
SAS Journal of Medicine Pub Date : 2023-07-21 DOI: 10.36347/sasjm.2023.v09i07.006
Sophia Lebbar, M. Darfaoui, A. Omrani, M. Khouchani
{"title":"Proton Therapy for Nasopharyngeal Cancer: A Systematic Review","authors":"Sophia Lebbar, M. Darfaoui, A. Omrani, M. Khouchani","doi":"10.36347/sasjm.2023.v09i07.006","DOIUrl":"https://doi.org/10.36347/sasjm.2023.v09i07.006","url":null,"abstract":"Nasopharyngeal cancer presents unique challenges due to its complex anatomical location and proximity to critical organs. This systematic review examines the relevance of proton therapy in treating nasopharyngeal cancer. Twenty-six articles met the inclusion criteria, comprising conceptual studies, practical evaluations of proton therapy, and assessments of acute toxicities. Proton therapy demonstrated comparable tumor conformation and lower doses to organs at risk (OARs) compared to intensity-modulated radiotherapy (IMRT). Preliminary evidence suggests that proton therapy is at least as effective as IMRT and may be less toxic. Proton therapy shows promise for primary treatment, boosting after photon therapy, salvage situations, and pediatric populations, but careful attention to OAR doses is crucial. However, large randomized clinical trials are needed to establish its superiority and assess long-term outcomes.","PeriodicalId":193141,"journal":{"name":"SAS Journal of Medicine","volume":"21 10-11","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"120931320","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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