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Nihon saikingaku zasshi. Japanese journal of bacteriology最新文献

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[Workshop]. (车间)。
Nihon saikingaku zasshi. Japanese journal of bacteriology Pub Date : 2020-01-01 DOI: 10.3412/jsb.75.36
Susann Fischer, M. Marchis, Mario Navarro
{"title":"[Workshop].","authors":"Susann Fischer, M. Marchis, Mario Navarro","doi":"10.3412/jsb.75.36","DOIUrl":"https://doi.org/10.3412/jsb.75.36","url":null,"abstract":"Climate change mitigation and other pressing environmental needs call for technological innovations in sustainable development. Some efforts to develop \"green\" technologies are in fact currently being undertaken, mainly in OECD countries and some of the major emerging economies. In addition to environmental objectives, governments and firms increasingly recognize the opportunities to build competitive advantages in the rapidly growing area of green technologies.","PeriodicalId":19308,"journal":{"name":"Nihon saikingaku zasshi. Japanese journal of bacteriology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77912007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 103
[Investigation of pneumococcal virulence factors in the infection process]. [感染过程中肺炎球菌毒力因子的调查]。
Nihon saikingaku zasshi. Japanese journal of bacteriology Pub Date : 2020-01-01 DOI: 10.3412/jsb.75.173
Masaya Yamaguchi
{"title":"[Investigation of pneumococcal virulence factors in the infection process].","authors":"Masaya Yamaguchi","doi":"10.3412/jsb.75.173","DOIUrl":"https://doi.org/10.3412/jsb.75.173","url":null,"abstract":"<p><p>This review summarizes current knowledge regarding the pathological mechanism of Streptococcus pneumoniae, a major cause of pneumonia, sepsis, and meningitis, with focus on our previously presented studies.To identify pneumococcal adhesins or invasins on cell surfaces, we investigated several proteins with an LPXTG anchoring motif and identified one showing interaction with human fibronectin, which was designated PfbA. Next, the mechanism of pneumococcal evasion form host immunity system in blood was examined and pneumococcal α-Enolase was found to function as a neutrophil extracellular trap induction factor. Although S. pneumoniae organisms are partially killed by iron ion-induced free radicals, they have an ability to invade red blood cells and then evade antibiotics, neutrophil phagocytosis, and H<sub>2</sub>O<sub>2</sub> killing. In addition, our findings have indicated that zinc metalloprotease ZmpC suppresses pneumococcal virulence by inhibiting bacterial invasion of the central nervous system. Since evolutionarily conserved virulence factors are potential candidate therapeutic targets, we performed molecular evolutionary analyses, which revealed that cbpJ had the highest rate of codons under negative selection to total number of codons among genes encoding choline-binding proteins. Our experimental analysis results indicated that CbpJ functions as a virulence factor in pneumococcal pneumonia by contributing to evasion of neutrophil killing.Use of a molecular biological approach based on bacterial genome sequences, clinical disease states, and molecular evolutionary analysis is an effective strategy for revealing virulence factors and important therapeutic targets.</p>","PeriodicalId":19308,"journal":{"name":"Nihon saikingaku zasshi. Japanese journal of bacteriology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38750024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[International Symposium]. (国际研讨会)。
Nihon saikingaku zasshi. Japanese journal of bacteriology Pub Date : 2020-01-01 DOI: 10.3412/jsb.75.3
Sari Hanifi
{"title":"[International Symposium].","authors":"Sari Hanifi","doi":"10.3412/jsb.75.3","DOIUrl":"https://doi.org/10.3412/jsb.75.3","url":null,"abstract":"General Remarks The Nobel Prize in Literature is the most widely known and most prestigious literature prize worldwide. Since its first distribution in 1901, the prize has established itself as the epitome of cultural value. Considering this stature of the Nobel Prize, it is all the more remarkable that its ways of functioning and actual influence on the global literary field remain little known and poorly understood. This may have something to do with the fact that systematic research into the function and impact of the Nobel Prize in Literature and its effects in the literary field is a task of enormous dimension and staggering complexity. Taking recent scholarship on awards and vocational prizes, recognition and esteem, comparative literature, and the sociology of literature as a starting point, we would like to take on this task head-on and invite experts from around the globe to an international and interdisciplinary Nobel Prize symposium at the German Literature Archive, Marbach.","PeriodicalId":19308,"journal":{"name":"Nihon saikingaku zasshi. Japanese journal of bacteriology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91032159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Mechanism of bacterial motility]. [细菌运动机制]。
Nihon saikingaku zasshi. Japanese journal of bacteriology Pub Date : 2019-01-01 DOI: 10.3412/jsb.74.157
Shuichi Nakamura
{"title":"[Mechanism of bacterial motility].","authors":"Shuichi Nakamura","doi":"10.3412/jsb.74.157","DOIUrl":"https://doi.org/10.3412/jsb.74.157","url":null,"abstract":"Bacteria, life living at microscale, can spread only by thermal fluctuation. However, the ability of directional movement, such as swimming by rotating flagella, gliding over surfaces via mobile cell-surface adhesins, and actin-dependent movement, could be useful for thriving through searching more favorable environments, and such motility is known to be related to pathogenicity. Among diverse migration mechanisms, perhaps flagella-dependent motility would be used by most species. The bacterial flagellum is a molecular nanomachine comprising a helical filament and a basal motor, which is fueled by an electrochemical gradient of cation across the cell membrane (ion motive force). Many species, such as Escherichia coli, possess flagella on the outside of the cell body, whereas flagella of spirochetes reside within the periplasmic space. Flagellar filaments or helical spirochete bodies rotate like a screw propeller, generating propulsive force. This review article describes the current knowledge of the structure and operation mechanism of the bacterial flagellum, and flagella-dependent motility in highly viscous environments.","PeriodicalId":19308,"journal":{"name":"Nihon saikingaku zasshi. Japanese journal of bacteriology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79003804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
[Digital Poster]. (数字海报)。
Nihon saikingaku zasshi. Japanese journal of bacteriology Pub Date : 2019-01-01 DOI: 10.3412/jsb.74.44
{"title":"[Digital Poster].","authors":"","doi":"10.3412/jsb.74.44","DOIUrl":"https://doi.org/10.3412/jsb.74.44","url":null,"abstract":"","PeriodicalId":19308,"journal":{"name":"Nihon saikingaku zasshi. Japanese journal of bacteriology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37085366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Award Lecture].
Nihon saikingaku zasshi. Japanese journal of bacteriology Pub Date : 2019-01-01 DOI: 10.3412/jsb.74.1
{"title":"[Award Lecture].","authors":"","doi":"10.3412/jsb.74.1","DOIUrl":"https://doi.org/10.3412/jsb.74.1","url":null,"abstract":"","PeriodicalId":19308,"journal":{"name":"Nihon saikingaku zasshi. Japanese journal of bacteriology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75870622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Molecular biological studies toward controlling infectious diseases caused by multidrug-resistant Pseudomonas aeruginosa]. [控制多重耐药铜绿假单胞菌引起的传染病的分子生物学研究]。
Nihon saikingaku zasshi. Japanese journal of bacteriology Pub Date : 2019-01-01 DOI: 10.3412/jsb.74.177
Tomoe Kitao
{"title":"[Molecular biological studies toward controlling infectious diseases caused by multidrug-resistant Pseudomonas aeruginosa].","authors":"Tomoe Kitao","doi":"10.3412/jsb.74.177","DOIUrl":"https://doi.org/10.3412/jsb.74.177","url":null,"abstract":"<p><p>Pseudomonas aeruginosa is an opportunistic Gram-negative pathogen that causes serious acute, persistent, and relapsing infections. Recent year, the effectiveness of antibiotics for eliminating P. aeruginosa infections has been further complicated by the emergence of multidrug-resistant strains. Thus, new approaches for the rapid detection and novel antimicrobial drug discovery are urgently needed to control such intractable infections caused by the pathogen. Also, we do need deep understanding of the drug resistance mechanisms to overcome this issue. Here I describe a brief review on my biological studies toward controlling infectious diseases caused by multidrug-resistant P. aeruginosa.</p>","PeriodicalId":19308,"journal":{"name":"Nihon saikingaku zasshi. Japanese journal of bacteriology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3412/jsb.74.177","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37513818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[International Symposium]. (国际研讨会)。
Nihon saikingaku zasshi. Japanese journal of bacteriology Pub Date : 2019-01-01 DOI: 10.3412/jsb.74.4
Yumi Iwamatsu, K. Shimoda, H. Abe, T. Tani, M. Okawa, H. Miyaoka, Ross Buck
{"title":"[International Symposium].","authors":"Yumi Iwamatsu, K. Shimoda, H. Abe, T. Tani, M. Okawa, H. Miyaoka, Ross Buck","doi":"10.3412/jsb.74.4","DOIUrl":"https://doi.org/10.3412/jsb.74.4","url":null,"abstract":"","PeriodicalId":19308,"journal":{"name":"Nihon saikingaku zasshi. Japanese journal of bacteriology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90155982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Mechanism of intestinal absorption of botulinum neurotoxin complex]. 肉毒杆菌神经毒素复合物的肠道吸收机制。
Nihon saikingaku zasshi. Japanese journal of bacteriology Pub Date : 2019-01-01 DOI: 10.3412/jsb.74.167
T. Matsumura
{"title":"[Mechanism of intestinal absorption of botulinum neurotoxin complex].","authors":"T. Matsumura","doi":"10.3412/jsb.74.167","DOIUrl":"https://doi.org/10.3412/jsb.74.167","url":null,"abstract":"Botulinum neurotoxins (BoNTs) produced by the anaerobic bacterium Clostridium botulinum and related species cause botulism, a neuroparalytic disease associated with a high mortality. BoNTs are always produced as large protein complexes (progenitor toxin complexes, PTCs) through association with non-toxic components (NAPs) including hemagglutinin (HA) and non-toxic non-hemagglutinin (NTNHA). Food-borne botulism is caused by the ingestion of PTCs. PTCs in the gastrointestinal tract cross the intestinal epithelial barrier, enter the blood stream, and reach the nerve endings, where BoNTs cleave the SNAREs required for vesicle fusion. Consequently, BoNTs inhibit neurotransmitter release and cause paralysis. To cause food-borne botulism, BoNTs must traverse the intestinal epithelial barrier. However, the mechanism used to cross this barrier remains unclear. Using an in vitro epithelial barrier system, we previously showed that the interaction of HA with E-cadherin results in disruption of tight junctions. Furthermore, we previously reported that microfold (M) cells in the follicle-associated epithelium (FAE) of mouse Peyer's patches (PPs) are major sites where type A1 BoNT breaches the intestinal epithelial barrier. Here, I would like to demonstrate an ingenious invasion mechanism of the BoNT complex.","PeriodicalId":19308,"journal":{"name":"Nihon saikingaku zasshi. Japanese journal of bacteriology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85920657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Selective autophagy mechanism against Group A Streptococcus infection]. [抗A群链球菌感染的选择性自噬机制]。
Nihon saikingaku zasshi. Japanese journal of bacteriology Pub Date : 2018-01-01 DOI: 10.3412/jsb.73.193
Takashi Nozawa
{"title":"[Selective autophagy mechanism against Group A Streptococcus infection].","authors":"Takashi Nozawa","doi":"10.3412/jsb.73.193","DOIUrl":"https://doi.org/10.3412/jsb.73.193","url":null,"abstract":"<p><p>Autophagy acts as an intracellular host defense system against invading pathogenic microorganisms such as Group A Streptococcus (GAS). Autophagy is a membrane-mediated degradation system that is regulated by intracellular membrane trafficking regulators, including small GTPase Rab proteins. Here, we revealed Rab GTPase network that regulate autophagosome formation against GAS. A unique set of Rab GTPases coordinates autophagy to enable to form huge autophagosomes surrounding GAS by linking recycling endosomes and trans Golgi-network. We also found that NLRP4, one of intracellular pathogen recognition receptor, directs Rho signaling to facilitate autophagosome formation. In this article, we would like to show our findings on how host autophagy regulators coordinate autophagy during GAS infection.</p>","PeriodicalId":19308,"journal":{"name":"Nihon saikingaku zasshi. Japanese journal of bacteriology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3412/jsb.73.193","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36436792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
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