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Nihon saikingaku zasshi. Japanese journal of bacteriology最新文献

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[Viewing sepsis and autoimmune disease in relation with infection and NETs-formation]. [观察败血症和自身免疫性疾病与感染和nets形成的关系]。
Nihon saikingaku zasshi. Japanese journal of bacteriology Pub Date : 2018-01-01 DOI: 10.3412/jsb.73.171
Akio Matsuhisa, Akira Okui, Yoshiyuki Horiuchi
{"title":"[Viewing sepsis and autoimmune disease in relation with infection and NETs-formation].","authors":"Akio Matsuhisa,&nbsp;Akira Okui,&nbsp;Yoshiyuki Horiuchi","doi":"10.3412/jsb.73.171","DOIUrl":"https://doi.org/10.3412/jsb.73.171","url":null,"abstract":"<p><p>Neutrophil has been widely recognized as body's first line of defence against pathogens. NETosis was first reported in 2004 as a programmed cell death of neutrophil and distinguished from apoptosis and necrosis. This phenomenon has been already observed in both basic and clinical research. NETosis is induced by various stimulants such as PMA, IL-8, DAMPs/PAMPs, bacteria, and antigen-antibody complex including self-antibody such as ANCA. It is known that there are two types of NETosis following bacterial infections. Although both of them have the ability to capture and kill bacteria, they also damage the host tissues. The inhibition of the NETs-related enzymes prevents the NETs formation at that time. The production of O<sub>2</sub><sup>-</sup> from respiratory burst of neutrophils triggers NETs formation. In the first type of NETosis, neutrophils are completely collapsed, while in the second type, they maintain the morphology and the ability of phagocytosis. However, bacteria can escape from NETs by degrading NETs with their secreting nucleases. Thus the animal models of infection, using these bacteria, oftentimes suffer from severe infectious diseases. Human CGD (Chronic Granulomatosis Disease) patients who do not have Nox2 are immunocompromised, and highly susceptible to infection due to the defect of NETs formation. On the other hand, SLE patients are unable to break down the NETs as their serum inhibits the DNase1 activity, which results in autoantibody generation against NETs as well as self-DNA. It is getting clear that there is a relationship between inflammatory diseases, including infectious diseases, Sepsis and autoimmune diseases, and NETs. Therefore, it is important to re-evaluate the inflammatory disorders from NETs' perspective, and to incorporate the emerging concepts for better understanding the mechanisms involved.</p>","PeriodicalId":19308,"journal":{"name":"Nihon saikingaku zasshi. Japanese journal of bacteriology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3412/jsb.73.171","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40439877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
[JKIMS Joint Symposium]. [JKIMS联合研讨会]。
Nihon saikingaku zasshi. Japanese journal of bacteriology Pub Date : 2018-01-01 DOI: 10.3412/jsb.73.1
{"title":"[JKIMS Joint Symposium].","authors":"","doi":"10.3412/jsb.73.1","DOIUrl":"https://doi.org/10.3412/jsb.73.1","url":null,"abstract":"","PeriodicalId":19308,"journal":{"name":"Nihon saikingaku zasshi. Japanese journal of bacteriology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35861793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[International Symposium]. (国际研讨会)。
Nihon saikingaku zasshi. Japanese journal of bacteriology Pub Date : 2018-01-01 DOI: 10.3412/jsb.73.3
{"title":"[International Symposium].","authors":"","doi":"10.3412/jsb.73.3","DOIUrl":"https://doi.org/10.3412/jsb.73.3","url":null,"abstract":"","PeriodicalId":19308,"journal":{"name":"Nihon saikingaku zasshi. Japanese journal of bacteriology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35861797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 11
[Workshop]. (车间)。
Nihon saikingaku zasshi. Japanese journal of bacteriology Pub Date : 2018-01-01 DOI: 10.3412/jsb.73.21
{"title":"[Workshop].","authors":"","doi":"10.3412/jsb.73.21","DOIUrl":"https://doi.org/10.3412/jsb.73.21","url":null,"abstract":"","PeriodicalId":19308,"journal":{"name":"Nihon saikingaku zasshi. Japanese journal of bacteriology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35861796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Poster]. (海报)。
Nihon saikingaku zasshi. Japanese journal of bacteriology Pub Date : 2018-01-01 DOI: 10.3412/jsb.73.50
{"title":"[Poster].","authors":"","doi":"10.3412/jsb.73.50","DOIUrl":"https://doi.org/10.3412/jsb.73.50","url":null,"abstract":"","PeriodicalId":19308,"journal":{"name":"Nihon saikingaku zasshi. Japanese journal of bacteriology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3412/jsb.73.50","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35861798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Luncheon Seminar]. (午餐研讨会)。
Nihon saikingaku zasshi. Japanese journal of bacteriology Pub Date : 2018-01-01 DOI: 10.3412/jsb.73.154
{"title":"[Luncheon Seminar].","authors":"","doi":"10.3412/jsb.73.154","DOIUrl":"https://doi.org/10.3412/jsb.73.154","url":null,"abstract":"","PeriodicalId":19308,"journal":{"name":"Nihon saikingaku zasshi. Japanese journal of bacteriology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3412/jsb.73.154","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35861794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Symposium]. (研讨会)。
Nihon saikingaku zasshi. Japanese journal of bacteriology Pub Date : 2018-01-01 DOI: 10.3412/jsb.73.6
{"title":"[Symposium].","authors":"","doi":"10.3412/jsb.73.6","DOIUrl":"https://doi.org/10.3412/jsb.73.6","url":null,"abstract":"","PeriodicalId":19308,"journal":{"name":"Nihon saikingaku zasshi. Japanese journal of bacteriology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35861799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Creation of synthetic bacterial viruses]. [合成细菌病毒的产生]。
Nihon saikingaku zasshi. Japanese journal of bacteriology Pub Date : 2018-01-01 DOI: 10.3412/jsb.73.201
Hiroki Ando
{"title":"[Creation of synthetic bacterial viruses].","authors":"Hiroki Ando","doi":"10.3412/jsb.73.201","DOIUrl":"https://doi.org/10.3412/jsb.73.201","url":null,"abstract":"<p><p>Bacteria are closely related with human health and diseases. For example, the emergence of drug-resistant bacteria is a serious problem in the world. Studying the human microbiome shows its important role for our health. But we have very limited tools to edit bacterial population. Antibiotics are generally broad-spectrum and unable to kill only bad bacteria. The natural enemies of bacteria, called bacteriophage (phage), have highly specific host range, and thus promising candidates for targeted bacterial population editing. However, isolation and characterization of natural phages can be a time-, labor- and cost-intensive way. Also, developing phage-based therapeutics and diagnostics is limited by the difficulty of engineering phages. Here, I describe a phage genome-engineering platform and synthetic phages with tunable host ranges to overcome these challenges.</p>","PeriodicalId":19308,"journal":{"name":"Nihon saikingaku zasshi. Japanese journal of bacteriology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3412/jsb.73.201","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36726087","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Index]. (索引)。
Nihon saikingaku zasshi. Japanese journal of bacteriology Pub Date : 2018-01-01 DOI: 10.3412/jsb.73.156
{"title":"[Index].","authors":"","doi":"10.3412/jsb.73.156","DOIUrl":"https://doi.org/10.3412/jsb.73.156","url":null,"abstract":"","PeriodicalId":19308,"journal":{"name":"Nihon saikingaku zasshi. Japanese journal of bacteriology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35861795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Luncheon Seminar. 午餐研讨会。
Nihon saikingaku zasshi. Japanese journal of bacteriology Pub Date : 2017-01-01 DOI: 10.3412/jsb.72.172
{"title":"Luncheon Seminar.","authors":"","doi":"10.3412/jsb.72.172","DOIUrl":"https://doi.org/10.3412/jsb.72.172","url":null,"abstract":"","PeriodicalId":19308,"journal":{"name":"Nihon saikingaku zasshi. Japanese journal of bacteriology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34765229","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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