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Hand Dexterity Recovery Capacity for Degenerative Cervical Myelopathy With Varying Levels of Impairment: A Prospective 1-Year Follow-up Study. 不同程度损伤的退行性脊髓型颈椎病患者的手灵活性恢复能力:一项前瞻性1年随访研究。
IF 3.8 2区 医学
Neurospine Pub Date : 2025-03-01 Epub Date: 2024-12-22 DOI: 10.14245/ns.2448682.341
Guoyan Liang, Tianying Liao, Yongyu Ye, Yi Cai, Junying Chen, Yunbing Chang
{"title":"Hand Dexterity Recovery Capacity for Degenerative Cervical Myelopathy With Varying Levels of Impairment: A Prospective 1-Year Follow-up Study.","authors":"Guoyan Liang, Tianying Liao, Yongyu Ye, Yi Cai, Junying Chen, Yunbing Chang","doi":"10.14245/ns.2448682.341","DOIUrl":"10.14245/ns.2448682.341","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to elucidate the hand function recovery capacity of degenerative cervical myelopathy (DCM) patients with different severities of hand dexterity impairment.</p><p><strong>Methods: </strong>Hand functional outcome measures such as the 10-second grip and release (10s-G&R) test, modified Japanese Orthopaedic Association (mJOA) upper extremity score and Japanese Orthopaedic Association Cervical Myelopathy Evaluation Questionnaire (JOACMEQ) upper extremity function were collected before surgery and at the 1-year follow-up. A total of 102 DCM patients were categorized into mild, moderate and severe group based on the preoperative 10s-G&R test result. Hand functional parameters were compared across the 3 groups. Multivariate linear regression was conducted to explore predictive factors. Receiver operating characteristic curve analysis was performed to assess the predictive efficacy of the preoperative 10s-G&R test and establish the cutoff value for incomplete recovery of hand dexterity.</p><p><strong>Results: </strong>At the 1-year follow-up, significant improvements were observed in all hand functional parameters across all 3 groups. However, the incomplete recovery rates of the mild, moderate, severe groups were 26.67%, 46.88%, and 57.50%, respectively (p < 0.05). Multivariate regression revealed that preoperative 10s-G&R test result, age, Hoffmann sign, duration of symptom, and mJOA Upper score serve as significant predictors for postoperative 10s-G&R test outcomes. Patients with a preoperative 10s-G&R test < 15 cycles have a 1.9 times higher risk of incomplete recovery of hand function (p = 0.005).</p><p><strong>Conclusion: </strong>Most patients, regardless of their preoperative hand function, exhibit potential for improvement in hand dexterity. However, worse initial hand dexterity correlates with poorer outcomes. Surgical treatment is recommended before the 10s-G&R test drops below 15 cycles.</p>","PeriodicalId":19269,"journal":{"name":"Neurospine","volume":" ","pages":"202-210"},"PeriodicalIF":3.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12010846/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142915426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Predicting Postoperative Progression of Ossification of the Posterior Longitudinal Ligament in the Cervical Spine Using Interpretable Radiomics Models. 使用可解释的放射组学模型预测颈椎后纵韧带骨化的术后进展。
IF 3.8 2区 医学
Neurospine Pub Date : 2025-03-01 Epub Date: 2025-03-31 DOI: 10.14245/ns.2448846.423
Siyuan Qin, Ruomu Qu, Ke Liu, Ruixin Yan, Weili Zhao, Jun Xu, Enlong Zhang, Feifei Zhou, Ning Lang
{"title":"Predicting Postoperative Progression of Ossification of the Posterior Longitudinal Ligament in the Cervical Spine Using Interpretable Radiomics Models.","authors":"Siyuan Qin, Ruomu Qu, Ke Liu, Ruixin Yan, Weili Zhao, Jun Xu, Enlong Zhang, Feifei Zhou, Ning Lang","doi":"10.14245/ns.2448846.423","DOIUrl":"https://doi.org/10.14245/ns.2448846.423","url":null,"abstract":"<p><strong>Objective: </strong>This study investigates the potential of radiomics to predict postoperative progression of ossification of the posterior longitudinal ligament (OPLL) after posterior cervical spine surgery.</p><p><strong>Methods: </strong>This retrospective study included 473 patients diagnosed with OPLL at Peking University Third Hospital between October 2006 and September 2022. Patients underwent posterior spinal surgery and had at least 2 computed tomography (CT) examinations spaced at least 1 year apart. OPLL progression was defined as an annual growth rate exceeding 7.5%. Radiomic features were extracted from preoperative CT images of the OPLL lesions, followed by feature selection using correlation coefficient analysis and least absolute shrinkage and selection operator, and dimensionality reduction using principal component analysis. Univariable analysis identified significant clinical variables for constructing the clinical model. Logistic regression models, including the Rad-score model, clinical model, and combined model, were developed to predict OPLL progression.</p><p><strong>Results: </strong>Of the 473 patients, 191 (40.4%) experienced OPLL progression. On the testing set, the combined model, which incorporated the Rad-score and clinical variables (area under the receiver operating characteristic curve [AUC] = 0.751), outperformed both the radiomics-only model (AUC = 0.693) and the clinical model (AUC = 0.620). Calibration curves demonstrated good agreement between predicted probabilities and observed outcomes, and decision curve analysis confirmed the clinical utility of the combined model. SHAP (SHapley Additive exPlanations) analysis indicated that the Rad-score and age were key contributors to the model's predictions, enhancing clinical interpretability.</p><p><strong>Conclusion: </strong>Radiomics, combined with clinical variables, provides a valuable predictive tool for assessing the risk of postoperative progression in cervical OPLL, supporting more personalized treatment strategies. Prospective, multicenter validation is needed to confirm the utility of the model in broader clinical settings.</p>","PeriodicalId":19269,"journal":{"name":"Neurospine","volume":"22 1","pages":"144-156"},"PeriodicalIF":3.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12010848/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144032699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence and Risk Factors for Postoperative Neurological Complications in Spinal Deformity Surgery: A Systematic Review and Proportional Meta-Analysis. 脊柱畸形手术后神经系统并发症的患病率和危险因素:系统回顾和比例荟萃分析。
IF 3.8 2区 医学
Neurospine Pub Date : 2025-03-01 Epub Date: 2025-03-31 DOI: 10.14245/ns.2449364.682
Yam Wa Man, Jedidiah Yui Shing Lui, Chor Yin Lam, Jason Pui Yin Cheung, Prudence Wing Hang Cheung
{"title":"Prevalence and Risk Factors for Postoperative Neurological Complications in Spinal Deformity Surgery: A Systematic Review and Proportional Meta-Analysis.","authors":"Yam Wa Man, Jedidiah Yui Shing Lui, Chor Yin Lam, Jason Pui Yin Cheung, Prudence Wing Hang Cheung","doi":"10.14245/ns.2449364.682","DOIUrl":"https://doi.org/10.14245/ns.2449364.682","url":null,"abstract":"<p><strong>Objective: </strong>To investigate the incidence of postoperative neurological complications among patients who underwent spinal deformity surgery and to determine the significant risk factors for postoperative neurological complications.</p><p><strong>Methods: </strong>Six databases PubMed, Web of Science, Scopus, MEDLINE, Embase, and Cochrane Library have been searched to identify observational studies from inception until January 2025. Inclusion criteria were patients aged ≥10 years with postoperative neurological complications after spinal deformity surgery. Stata/MP18.0 was used to conduct the meta-analysis in this review. The summary incidence estimates, proportion with 95% confidence intervals (CIs) and weights were pooled by the random-effects restricted maximum likelihood model.</p><p><strong>Results: </strong>The search strategy identified 53 articles with 40,958 patients for final review. Overall incidence of postoperative neurological complications was 7% (95% CI, 5.0%-9.0%; p < 0.001; I2 = 98.34%) in which incidence estimates for patients with adult spinal deformity and underwent 3-column spinal osteotomies were 12% (95% CI, 9%-16%; p < 0.001; I2 = 93.17%) and 18% (95% CI, 8%-31%; p < 0.001; I2 = 94.68%) respectively. Preoperative neurological deficit was the risk factor with highest overall odds ratio (OR, 2.86; 95% CI, 1.85-4.41; p = 0.01; I2 = 76.20%), followed by the presence of kyphosis (OR, 1.13; 95% CI, 0.75-1.70; p = 0.02; I2 = 81.80%) and age at surgery (OR, 1.04; 95% CI, 1.01-1.08; p = 0.04; I2 = 68.80%).</p><p><strong>Conclusion: </strong>Preoperative neurological deficit, the presence of kyphosis and age at surgery were significant risk factors for postoperative neurological complications. Therefore, comprehensive preoperative assessment and surgical planning are crucial to minimize the risk of developing postoperative neurological complications or the deterioration of pre-existing neurologic deficits.</p>","PeriodicalId":19269,"journal":{"name":"Neurospine","volume":"22 1","pages":"243-263"},"PeriodicalIF":3.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12010854/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144030141","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Does Vertebral Cement Augmentation Reduce Postoperative Proximal Junction Complications in Spinal Deformity Corrective Surgery: A Systematic Review and Meta-analysis. 椎体水泥增强术是否能减少脊柱畸形矫正手术后近端交界处并发症:一项系统综述和荟萃分析
IF 3.8 2区 医学
Neurospine Pub Date : 2025-03-01 Epub Date: 2025-03-31 DOI: 10.14245/ns.2449334.667
Dong Li, Xin Sun, Jie Li, Yanjie Xu, Yong Qiu, Zezhang Zhu, Zhen Liu
{"title":"Does Vertebral Cement Augmentation Reduce Postoperative Proximal Junction Complications in Spinal Deformity Corrective Surgery: A Systematic Review and Meta-analysis.","authors":"Dong Li, Xin Sun, Jie Li, Yanjie Xu, Yong Qiu, Zezhang Zhu, Zhen Liu","doi":"10.14245/ns.2449334.667","DOIUrl":"https://doi.org/10.14245/ns.2449334.667","url":null,"abstract":"<p><strong>Objective: </strong>To assess the effectiveness of vertebral cement augmentation (VCA) at upper instrumented vertebra (UIV) and UIV+1 in preventing proximal junction complications in correction surgery for adult spinal deformity patients.</p><p><strong>Methods: </strong>A literature search was conducted on Web of Science, PubMed, and Cochrane Library databases for comparative studies published before December 30th, 2024. Two reviewers independently screened eligible articles based on the inclusion and exclusion criteria, assessed study quality with Newcastle-Ottawa scale, and extracted data like study characteristics, surgical details, primary and secondary outcomes. Data analysis was performed using Review Manager 5.4 and Stata software.</p><p><strong>Results: </strong>Of all 513 papers screened, a meta-analysis was conducted on 7 articles, which included 333 cases in the VCA group and 827 cases in the control group. Patients in the VCA group had significantly older age and lower T score than patients in the control group. Although there was no statistically significant difference in the incidence of proximal junctional failure between the 2 groups, the results of the meta-analysis showed that the incidence of proximal junctional failure and the need for revision surgery were reduced by 36% and 71%, respectively, in the VCA group. One study reported 2 clinically silent pulmonary cement embolism and 1 patient requiring surgical decompression for cement leak into the spinal canal.</p><p><strong>Conclusion: </strong>This meta-analysis supported the use of VCA in corrective surgery for spinal deformities patients, especially in patients with advanced age and osteoporosis.</p>","PeriodicalId":19269,"journal":{"name":"Neurospine","volume":"22 1","pages":"51-66"},"PeriodicalIF":3.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12010840/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144033893","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Anatomical Importance Between Neural Structure and Bony Landmark in Neuroventral Decompression for Posterior Endoscopic Cervical Discectomy. 后内镜颈椎间盘切除术神经腹侧减压中神经结构与骨标记的解剖学意义。
IF 3.8 2区 医学
Neurospine Pub Date : 2025-03-01 Epub Date: 2025-03-31 DOI: 10.14245/ns.2448794.397
Xin Wang, Tao Hu, Chaofan Qin, Bo Lei, Mingxin Chen, Ke Ma, Qingyan Long, Qingshuai Yu, Si Cheng, Zhengjian Yan
{"title":"Anatomical Importance Between Neural Structure and Bony Landmark in Neuroventral Decompression for Posterior Endoscopic Cervical Discectomy.","authors":"Xin Wang, Tao Hu, Chaofan Qin, Bo Lei, Mingxin Chen, Ke Ma, Qingyan Long, Qingshuai Yu, Si Cheng, Zhengjian Yan","doi":"10.14245/ns.2448794.397","DOIUrl":"https://doi.org/10.14245/ns.2448794.397","url":null,"abstract":"<p><strong>Objective: </strong>This study aims to investigate the anatomical relationship among the nerve roots, intervertebral space, pedicles, and intradural rootlets of the cervical spine for improving operative outcomes and exploring neuroventral decompression approach in posterior endoscopic cervical discectomy (PECD).</p><p><strong>Methods: </strong>Cervical computed tomography myelography imaging data from January 2021 to May 2023 were collected, and the RadiAnt DICOM Viewer Software was employed to conduct multiplane reconstruction. The following parameters were recorded: width of nerve root (WN), nerve root-superior pedicle distance (NSPD), nerve root-inferior pedicle distance (NIPD), and the relationship between the intervertebral space and the nerve root (shoulder, anterior, and axillary). Additionally, the descending angles between the spinal cord and the ventral (VRA) and dorsal (DRA) rootlets were measured.</p><p><strong>Results: </strong>The WN showed a gradual increase from C4 to C7, with measurements notably larger in men compared to women. The NSPD decreased gradually from the C2-3 to the C5-6 levels. However, the NIPD showed an opposite level-related change, notably larger than the NSPD at the C4-5, C5-6, and C7-T1 levels. Furthermore, significant differences in NIPD were observed between different age groups and genders. The incidence of the anterior type exhibited a gradual decrease from the C2-3 to the C5-6 levels. Conversely, the axillary type exhibited an opposite level-related change. Additionally, the VRA and DRA decreased as the level descended, with measurements significantly larger in females.</p><p><strong>Conclusion: </strong>A prediction of the positional relationship between the intervertebral space and the nerve root is essential for the direct neuroventral decompression in PECD to avoid damaging the neural structures. The axillary route of the nerve root offers a safer and more effective pathway for performing direct neuroventral decompression compared to the shoulder approach.</p>","PeriodicalId":19269,"journal":{"name":"Neurospine","volume":"22 1","pages":"286-296"},"PeriodicalIF":3.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12010839/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144028922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Distinct Recovery Patterns After Transforaminal Lumbar Interbody Fusion: Comparing Minimally Invasive and Open Approaches Using Mixed-Effects Segmented Regression. 经椎间孔腰椎椎体间融合术后不同的恢复模式:使用混合效应分段回归比较微创和开放入路。
IF 3.8 2区 医学
Neurospine Pub Date : 2025-03-01 Epub Date: 2025-03-31 DOI: 10.14245/ns.2550096.048
Tomoyuki Asada, Eric R Zhao, Adin M Ehrlich, Adrian Lui, Andrea Pezzi, Sereen Halayqeh, Tarek Harhash, Olivia C Tuma, Kasra Araghi, Todd J Albert, James Farmer, Russel C Huang, Harvinder Sandhu, Han Jo Kim, Francis C Lovecchio, James E Dowdell, Sravisht Iyer, Sheeraz A Qureshi
{"title":"Distinct Recovery Patterns After Transforaminal Lumbar Interbody Fusion: Comparing Minimally Invasive and Open Approaches Using Mixed-Effects Segmented Regression.","authors":"Tomoyuki Asada, Eric R Zhao, Adin M Ehrlich, Adrian Lui, Andrea Pezzi, Sereen Halayqeh, Tarek Harhash, Olivia C Tuma, Kasra Araghi, Todd J Albert, James Farmer, Russel C Huang, Harvinder Sandhu, Han Jo Kim, Francis C Lovecchio, James E Dowdell, Sravisht Iyer, Sheeraz A Qureshi","doi":"10.14245/ns.2550096.048","DOIUrl":"https://doi.org/10.14245/ns.2550096.048","url":null,"abstract":"<p><strong>Objective: </strong>While minimally invasive-transforaminal lumbar interbody fusion (MIS-TLIF) has shown superiority in key clinical metrics over the open approach, evidence regarding patient-reported outcomes remains limited. This study compared postoperative recovery trajectories and symptomatic improvement phases between MIS and open TLIF.</p><p><strong>Methods: </strong>This retrospective review included patients who underwent single-level MIS or open TLIF. Oswestry Disability Index (ODI) and Numerical Rating Scale (NRS) for back and leg pain were collected preoperatively and postoperatively. Segmented regression analysis with mixed-effects modeling, allowing for identification of distinct recovery phases, compared symptomatic trends between approaches.</p><p><strong>Results: </strong>Of 324 patients (268 MIS, 56 open), baseline demographics were similar except for greater preoperative leg pain in the MIS group (NRS: 6.0 vs. 5.0, p = 0.027). A segmented regression model identified 4 ODI recovery phases: postoperative disability phase (PDP, day 0 to 13), early improvement phase (day 13 to 28), late improvement phase (day 28 to 110), and plateau phase (later than day 110). The MIS group exhibited significantly lower disability exacerbation during PDP (β = 0.93 vs. 1.42 points per day, p = 0.008). Additionally, the plateau of NRS back occurred significantly earlier in the MIS group than in the open group (MIS, 26.7 ± 2.6 days vs. open, 51.7 ± 6.6 days, p < 0.001).</p><p><strong>Conclusion: </strong>MIS-TLIF resulted in lower postoperative disability during the first 2 weeks compared to the open approach. Furthermore, low back pain achieved an earlier plateau in back pain by about 4 weeks in the MIS approach.</p>","PeriodicalId":19269,"journal":{"name":"Neurospine","volume":"22 1","pages":"3-13"},"PeriodicalIF":3.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12010849/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144012532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correlation Between the Spinopelvic Parameters and Morphological Characteristics of Pedicle-Facet Joints in Different Lumbar Spondylolisthesis. 不同类型腰椎滑脱椎弓根-小关节形态特征与椎盂参数的关系。
IF 3.8 2区 医学
Neurospine Pub Date : 2025-03-01 Epub Date: 2025-03-31 DOI: 10.14245/ns.2448900.450
Baoqiang He, Yebo Leng, Shicai Xu, Yang Li, Jiajun Zhou, Min Kang, Yehui Liao, Minghao Tian, Qiang Tang, Fei Ma, Qing Wang, Chao Tang, Dejun Zhong
{"title":"Correlation Between the Spinopelvic Parameters and Morphological Characteristics of Pedicle-Facet Joints in Different Lumbar Spondylolisthesis.","authors":"Baoqiang He, Yebo Leng, Shicai Xu, Yang Li, Jiajun Zhou, Min Kang, Yehui Liao, Minghao Tian, Qiang Tang, Fei Ma, Qing Wang, Chao Tang, Dejun Zhong","doi":"10.14245/ns.2448900.450","DOIUrl":"https://doi.org/10.14245/ns.2448900.450","url":null,"abstract":"<p><strong>Objective: </strong>Based on spinopelvic parameters and biomechanical principles, the pedicle-facet joint (PFJ) morphological characteristics of isthmic and degenerative spondylolisthesis were analyzed, and the mechanism of their onset and progression was discussed.</p><p><strong>Methods: </strong>This retrospective cross-sectional study included 194 patients with L5 spondylolysis or L5-S1 low-grade isthmic spondylolisthesis (IS group), 172 patients with L4-5 degenerative spondylolisthesis (DS group), and 366 patients with nonlumbar spondylolysis (NL group). The spinopelvic parameters and PFJ morphological parameters of the patients were measured, the differences in these parameters among and within the 3 groups were compared, and the correlations were analyzed.</p><p><strong>Results: </strong>Sacral slope (SS) and lumbar lordosis (LL) were the highest in the IS group, the second highest in the DS group, and the lowest in the NL group. Among the 3 groups, the L4 facet joint angle (FJA) was the largest in the IS group, the second largest in the NL group, and the smallest in the DS group. The L4 pedicle-facet joint angle (PFA) was the largest in the DS group, the second largest in the IS group, and the smallest in the NL group. Pearson correlation analysis showed that within each group, SS and LL were negatively correlated with FJA and positively correlated with PFA.</p><p><strong>Conclusion: </strong>This study found a correlation between the PFJ morphological characteristics of patients with lumbar spondylolisthesis and spinopelvic parameters, suggesting that the morphological characteristics of PFJs may be caused by varying stresses under different spinopelvic morphologies.</p>","PeriodicalId":19269,"journal":{"name":"Neurospine","volume":"22 1","pages":"231-242"},"PeriodicalIF":3.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12010845/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143973945","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Loss of Mass and Surface Topography in 3-Dimensional-Printed Solid Titanium Cages Upon Impaction: An In Vitro Model. 三维打印固体钛笼在撞击后的质量损失和表面形貌:一个体外模型。
IF 3.8 2区 医学
Neurospine Pub Date : 2025-03-01 Epub Date: 2025-03-31 DOI: 10.14245/ns.2448990.495
Tien Tran, Ian M Singleton, Victor Ungurean, Andrea Rowland, Anna Martin, Oluwatodimu Richard Raji, Dimitriy G Kondrashov
{"title":"Loss of Mass and Surface Topography in 3-Dimensional-Printed Solid Titanium Cages Upon Impaction: An In Vitro Model.","authors":"Tien Tran, Ian M Singleton, Victor Ungurean, Andrea Rowland, Anna Martin, Oluwatodimu Richard Raji, Dimitriy G Kondrashov","doi":"10.14245/ns.2448990.495","DOIUrl":"https://doi.org/10.14245/ns.2448990.495","url":null,"abstract":"<p><strong>Objective: </strong>There is increased use of 3-dimensional (3D)-printing for manufacturing of interbody cages to create microscale surface features that promote bone formation. Those features may be vulnerable to abrasion and/or delamination during cage impaction. Our objective was to quantify loss of mass and changes in surface topography of 3D-printed titanium interbody cages due to surgical impaction.</p><p><strong>Methods: </strong>Eight surfaces of four 3D-printed titanium modular interbody fusion cages were tested. The cages were impacted into the Sawbones model with compression preload of either 200N or 400N using a guided 1-lb (0.45 kg) drop weight. Mass and surface roughness parameters of each endplate were recorded and compared for differences.</p><p><strong>Results: </strong>Significant weight loss was observed for the superior endplate group and for both 200N and 400N preloads. For pooled data comparison, significant postimpaction decreases were observed for mean roughness, root-mean-squared roughness, mean roughness depth, and total height of roughness profile. No significant differences were observed for profile skewness and kurtosis. There were significant changes in almost all roughness parameters in the anterior region of the cage postimpaction with significant changes in 2 out of 6 parameters in the middle, posterior, and central regions postimpaction.</p><p><strong>Conclusion: </strong>Three-dimensional-printed titanium interbody fusion cages underwent loss of mass and alteration in surface topography during benchtop testing replicating physiologic conditions. There was an endplate- and region-specific postimpaction change in roughness parameters. The anterior surface experienced the largest change in surface parameters postimpaction. Our results have implications for future cage design and pre-approval testing of 3D-printed implants.</p>","PeriodicalId":19269,"journal":{"name":"Neurospine","volume":"22 1","pages":"173-184"},"PeriodicalIF":3.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12010865/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144029948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Commentary on "Does Vertebral Cement Augmentation Reduce Postoperative Proximal Junction Complications in Spinal Deformity Corrective Surgery: A Systematic Review and Meta-analysis". “椎体水泥增强术是否能减少脊柱畸形矫正手术后近端交界处并发症:一项系统综述和荟萃分析”。
IF 3.8 2区 医学
Neurospine Pub Date : 2025-03-01 Epub Date: 2025-03-31 DOI: 10.14245/ns.2550266.133
Byung Ho Lee, Jae Won Shin
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引用次数: 0
The Utilization of Navigation and Emerging Technologies With Endoscopic Spine Surgery: A Narrative Review. 导航和新兴技术在内窥镜脊柱手术中的应用:综述。
IF 3.8 2区 医学
Neurospine Pub Date : 2025-03-01 Epub Date: 2025-03-31 DOI: 10.14245/ns.2449404.702
Abhinav K Sharma, Rafael Garcia de Oliveira, Siravich Suvithayasiri, Piya Chavalparit, Chien Chun Chang, Yong H Kim, Charla R Fischer, Sang Lee, Samuel Cho, Jin-Sung Kim, Don Young Park
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引用次数: 0
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