Neurology最新文献

{"title":"Teaching NeuroImage: Atypical Presentation of HLA-B51 Positive Neuro-Behçet Disease in a 27-Year-Old Patient: The Waterfall Sign.","authors":"Majd A AbuAlrob","doi":"10.1212/wnl.0000000000210257","DOIUrl":"https://doi.org/10.1212/wnl.0000000000210257","url":null,"abstract":"","PeriodicalId":19256,"journal":{"name":"Neurology","volume":"14 1","pages":"e210257"},"PeriodicalIF":9.9,"publicationDate":"2024-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142887709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Author Response: Teaching NeuroImage: Fundoscopic and Optical Coherence Tomography Changes in Primary CNS Lymphoma.","authors":"Negar Moheb,Negar Moheb,W Oliver Tobin,Timothy W Olsen,John Jing-Wei Chen","doi":"10.1212/wnl.0000000000209733","DOIUrl":"https://doi.org/10.1212/wnl.0000000000209733","url":null,"abstract":"","PeriodicalId":19256,"journal":{"name":"Neurology","volume":"31 1","pages":"e209733"},"PeriodicalIF":9.9,"publicationDate":"2024-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142887712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Editors' Note: Teaching NeuroImage: Fundoscopic and Optical Coherence Tomography Changes in Primary CNS Lymphoma.","authors":"Ariane Lewis,Steven L Galetta","doi":"10.1212/wnl.0000000000210314","DOIUrl":"https://doi.org/10.1212/wnl.0000000000210314","url":null,"abstract":"","PeriodicalId":19256,"journal":{"name":"Neurology","volume":"153 1","pages":"e210314"},"PeriodicalIF":9.9,"publicationDate":"2024-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142887714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pearls & Oy-sters: Increased Visibility of Focal Cortical Dysplasia in Cerebral MRI During the First Year of Life.","authors":"Hishayine Visvaratnam,Christian M Korff,Margitta Seeck,Aikaterini Fitsiori","doi":"10.1212/wnl.0000000000210128","DOIUrl":"https://doi.org/10.1212/wnl.0000000000210128","url":null,"abstract":"Early detection of focal cortical dysplasia (FCD) using brain MRI in young children presenting with drug-resistant epilepsy may facilitate prompt surgical treatment, resulting in better control of seizures and decreased associated cognitive difficulties. Characteristics of FCD described in the literature are predominantly based on MRI findings in a fully myelinated brain; therefore, changes occurring during early brain maturation are not well known. In this case report, we describe distinct MRI features of a FCD visualized best before completion of myelination of the cortex and subcortical white matter. Specifically, this lesion exhibited increased visibility because of better delineation of the borders of the pathological area involved in the malformation compared with imaging obtained after completion of myelination. Although the pathophysiology of these imaging features necessitates further investigation, one hypothesis is that excessive neuronal input in young epileptic patients could trigger premature myelination of overstimulated fibers underlying the cortical epileptogenic focus. The aim of this case report was to raise awareness that seizures might induce local changes in brain myelination, which can be detected by MRI during the first year of life. Early identification of FCD may prompt surgical treatment in selected patients with drug-resistant epilepsy.","PeriodicalId":19256,"journal":{"name":"Neurology","volume":"30 1","pages":"e210128"},"PeriodicalIF":9.9,"publicationDate":"2024-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142887811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Large Nevus Sebaceous in a Newborn: Consider the Brain.","authors":"Bramhini Bhargavi Koneti,Bhanudeep Singanamalla","doi":"10.1212/wnl.0000000000210266","DOIUrl":"https://doi.org/10.1212/wnl.0000000000210266","url":null,"abstract":"","PeriodicalId":19256,"journal":{"name":"Neurology","volume":"25 1","pages":"e210266"},"PeriodicalIF":9.9,"publicationDate":"2024-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142887842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Editors' Note: Wall-Eyed Bilateral Internuclear Ophthalmoplegia Variant Syndrome Caused by Isolated Left Thalamic Infarction.","authors":"James E Siegler,Steven L Galetta","doi":"10.1212/wnl.0000000000210313","DOIUrl":"https://doi.org/10.1212/wnl.0000000000210313","url":null,"abstract":"","PeriodicalId":19256,"journal":{"name":"Neurology","volume":"124 1","pages":"e210313"},"PeriodicalIF":9.9,"publicationDate":"2024-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142887711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reader Response: Effects of Achieving Rapid, Intensive, and Sustained Blood Pressure Reduction in Intracerebral Hemorrhage Expansion and Functional Outcome.","authors":"Aditya Jhaveri,Caroline Alice Kellogg,James E Siegler","doi":"10.1212/wnl.0000000000209672","DOIUrl":"https://doi.org/10.1212/wnl.0000000000209672","url":null,"abstract":"","PeriodicalId":19256,"journal":{"name":"Neurology","volume":"15 1","pages":"e209672"},"PeriodicalIF":9.9,"publicationDate":"2024-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142887716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Challenges in Describing Tremor and Dystonia.","authors":"Aasef G Shaikh,Alfonso Fasano,Sanjay Pandey,Rick C Helmich,Alberto Albanese,Marie Vidailhet,Rodger Elble,Victor S C Fung,Marina Aj Tijssen,Beom S Jeon,Mark Hallett,Hyder Azad Jinnah","doi":"10.1212/wnl.0000000000210209","DOIUrl":"https://doi.org/10.1212/wnl.0000000000210209","url":null,"abstract":"Tremor is defined as an oscillatory and rhythmical movement. By contrast, dystonia is defined by sustained or intermittent abnormal postures, repetitive movements, or both. Tremor and dystonia often coexist in the same individual. Sometimes tremor and dystonia occur in the same body region, and sometimes they occur in separate body regions. In other cases, dystonic movements are rapid and repetitive, and they may mimic tremor. The varied clinical phenomenology of dystonia and tremor were recognized in the earliest descriptions of dystonia, and various terms have been used to describe the relationships between tremor and dystonia. The term dystonic tremor was first introduced to distinguish tremor-like movements in dystonia from more common tremors such as essential tremor. Subsequently, the same term was adopted to refer to any combination of dystonia and tremor in the same body region. Both applications of this term continue to be used in the modern literature. Other related terms have also been proposed such as tremor associated with dystonia, tremulous dystonia, dystonia-tremor syndrome, and dystonia with tremor. The proliferation of terms has become confusing, and expert opinion regarding application of these terms is divided, so a group of specialists was assembled to review the terminology and to develop recommendations for a more consistent approach. The group agreed that the term tremor should exclusively refer to rhythmic movements. The group also agreed that repetitive dystonic movements that are grossly arrhythmic should not be labeled with terms that imply they are a type of tremor. Moreover, when tremor and dystonia coexist, it may be clinically more useful to describe them separately, using descriptive terms rather than hybrid terms that imply suspected etiology. Easy-to-use clinical terms are essential, although bedside discrimination of movements may sometimes be challenging. In the future, motion analysis or physiologic measures may aid in the discrimination of movements that remain clinically uncertain.","PeriodicalId":19256,"journal":{"name":"Neurology","volume":"63 1","pages":"e210209"},"PeriodicalIF":9.9,"publicationDate":"2024-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142887717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Teaching NeuroImage: Notable MRI Findings in Sensory Ataxia Neuropathy, Dysarthria, and Ophthalmoplegia (SANDO), a POLG-Related Disorder.","authors":"Luziany Carvalho Araújo,Iago César Lopes Tenório de Cerqueira,Bianca de Aguiar Coelho Silva Madeiro","doi":"10.1212/wnl.0000000000210227","DOIUrl":"https://doi.org/10.1212/wnl.0000000000210227","url":null,"abstract":"","PeriodicalId":19256,"journal":{"name":"Neurology","volume":"123 1","pages":"e210227"},"PeriodicalIF":9.9,"publicationDate":"2024-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142887732","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Opinion & Special Articles: Beyond Pronouns-Educating Trainees on the Impact of Language on Gender Inclusivity in Neurologic Practice.","authors":"Chia-Chen Tsai,Judy Chen,Aleksandra Pikula,Emily L Johnson,Nicole Rosendale,Riley Bove,Z Paige L'Erario,Esther Bui","doi":"10.1212/wnl.0000000000210289","DOIUrl":"https://doi.org/10.1212/wnl.0000000000210289","url":null,"abstract":"Language plays an important role in ensuring gender inclusivity within neurology. Despite progress in language inclusivity, such as the emergence of explicit pronouns, more remains to be done. Historically, sex and gender have been used interchangeably, but they are, in fact, distinct concepts. This is an important distinction particularly in the care of transgender and gender diverse (TGD) individuals, whose assigned sex and gender are incongruent. In the health care setting, TGD individuals frequently report misgendering, identity invalidation, and gender pathologizing, which have led to health care avoidance and mistrust. Ultimately, to ensure effective integration of gender-affirming language into clinical care, training should be introduced early in neurology residency and fellowship education. Through 3 case studies in epilepsy, multiple sclerosis, and stroke, we discuss language use in neurology and provide recommendations to support trainees in the use of gender-affirming language. We underscore the importance of gender-affirming language in health care equity and cultivating a safe, inclusive clinical environment. It is crucial for residents and fellows to not only be informed on cultural humility and gender-affirming terminology but also learn to avoid assumptions and seek clarification about gender identity when needed. Ultimately, trainees proficient in these skills cultivate trust in clinical relationships, reduce discrimination against TGD populations, and improve patient health outcomes in neurologic care.","PeriodicalId":19256,"journal":{"name":"Neurology","volume":"33 1","pages":"e210289"},"PeriodicalIF":9.9,"publicationDate":"2024-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142887723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}