Nihon Kyobu Shikkan Gakkai zasshi最新文献_第6页

[The outcome of patients with mediastinal tumors detected by mass screening versus the outcome of those initially presentating with symptoms]. [通过大规模筛查发现的纵隔肿瘤患者的结果与最初出现症状的患者的结果]。

Nihon Kyobu Shikkan Gakkai zasshi Pub Date : 1997-11-25 DOI: 10.11389/JJRS1963.35.1205

T. Maeno, H. Satoh, H. Ishikawa, T. Naito, M. Ohtsuka, S. Hasegawa

引用次数: 0

[Expression of CD44 standard and CD44 variant 6 in human lung cancer]. [CD44标准型和CD44变体6在人肺癌中的表达]。

Nihon Kyobu Shikkan Gakkai zasshi Pub Date : 1997-11-25 DOI: 10.11389/JJRS1963.35.1179

S. Ochiai, Y. Nakanishi, K. Mizuno, S. Hashimoto, S. Inutsuka, M. Kawasaki, J. Yatsunami, N. Hara

{"title":"[Expression of CD44 standard and CD44 variant 6 in human lung cancer].","authors":"S. Ochiai, Y. Nakanishi, K. Mizuno, S. Hashimoto, S. Inutsuka, M. Kawasaki, J. Yatsunami, N. Hara","doi":"10.11389/JJRS1963.35.1179","DOIUrl":"https://doi.org/10.11389/JJRS1963.35.1179","url":null,"abstract":"We immunohistochemically examined the expression of CD44 standard (CD44 st) and CD44 variant 6 (CD44 v6) in 112 cases of primary lung cancer, and their relationship to the clinical milieu, including the clinical stage. In 46 cases of squamous cell carcinoma, expression of CD44 st was observed in 45.7% of the cases, and expression of CD44 v6 was observed in 60.9%. In 43 cases of adenocarcinoma, positive staining of CD44 st and CD44 v6 was seen in 2.3% and 4.7% of the cases, respectively. None of 21 small cell carcinomas was positive for CD44 st or CD44 v6. In squamous cell carcinomas, the expression of CD44 st and CD44 v6 was observed at a rate significantly higher than in other histologic type. Most specimens positive for CD44 st stained positively for CD44 v6. Therefore, it seems likely that the CD44 expression observed in squamous cell carcinoma of the lung was a variant CD44 containing the domain encoded by variant exon 6. The expression of CD44 v6 was not related to the clinical stage. Significant association between CD44 v6 and differentiation of squamous cell carcinoma was seen; 2/7 (28.6%) for poorly differentiated, 19/31 (61.3%) for moderately differentiated, and 7/8 (87.5%) for well differentiated squamous cell carcinomas (p = 0.02 by trend test). It was previously reported that CD44 st and CD44 v6 were expressed in both normal bronchial epithelium and squamous cell metaplasia. These results suggest that the expression of CD44 v6 in squamous cell carcinoma of the lung may reflect the immunohistochemical characteristics of the tissue from which such carcinoma emerge.","PeriodicalId":19255,"journal":{"name":"Nihon Kyobu Shikkan Gakkai zasshi","volume":"580 1","pages":"1179-85"},"PeriodicalIF":0.0,"publicationDate":"1997-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76414112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 9

[A patient with allergic bronchopulmonary candidiasis showing a high serum level of soluble interleukin 2 receptors]. [过敏性支气管肺念珠菌病患者血清可溶性白细胞介素2受体水平高]。

Nihon Kyobu Shikkan Gakkai zasshi Pub Date : 1997-11-25 DOI: 10.11389/JJRS1963.35.1271

N. Takabatake, S. Seino, H. Nakamura, H. Tomoike

{"title":"[A patient with allergic bronchopulmonary candidiasis showing a high serum level of soluble interleukin 2 receptors].","authors":"N. Takabatake, S. Seino, H. Nakamura, H. Tomoike","doi":"10.11389/JJRS1963.35.1271","DOIUrl":"https://doi.org/10.11389/JJRS1963.35.1271","url":null,"abstract":"An 84-year-old man was admitted to Yonezawa City Hospital with fever, cough, hemoptysis and progressive dyspnea. He had complained of wheezing asthmatoid and exertional dyspnea for the previous 10 years, regardless of the season. On admission, chest radiographs revealed a diffuse ground-glass shadow, fibrotic change, and volume reduction. Arterial blood gas analysis showed extreme hypoxemia. A computed tomographic (CT) scan of the chest showed not only faint ground-glass opacities and dense patches in the whole lung field, but also central bronchiectasis. Laboratory tests revealed that both total serum levels of IgE and specific IgE for Candida albicans were elevated. In the bronchoalveolar lavage fluid, lymphocyte, neutrophil and eosinophil percentages were high, and the CD4/CD8 ratio was low. We diagnosed the fibrotic stage of allergic bronchopulmonary candidiasis. During treatment with hydrocortisone and fluconazole, eosinophilia in the peripheral blood was observed, and serum candida antigen was positive. In addition, high serum levels of soluble interleukin 2 receptors were observed in this patient.","PeriodicalId":19255,"journal":{"name":"Nihon Kyobu Shikkan Gakkai zasshi","volume":"62 6 1","pages":"1271-7"},"PeriodicalIF":0.0,"publicationDate":"1997-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77573993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

[A case of primary endobronchial mucosa-associated lymphoid tissue lymphoma with middle lobe atelectasis]. [原发性支气管黏膜相关淋巴组织淋巴瘤合并中肺不张1例]。

Nihon Kyobu Shikkan Gakkai zasshi Pub Date : 1997-11-25 DOI: 10.11389/JJRS1963.35.1245

Yumi Naya, M. Ohe, Michihiro Fujino, Yasushi Akiyama, T. Kirisawa, Y. Kawakami

引用次数: 1

[Serum soluble adhesion molecules in patients with sarcoidosis]. [结节病患者血清可溶性黏附分子研究]。

Nihon Kyobu Shikkan Gakkai zasshi Pub Date : 1997-11-25 DOI: 10.11389/JJRS1963.35.1186

H. Mukae, J. Ashitani, H. Ihiboshi, H. Taniguchi, S. Matsukura, K. Iida, J. Kadota, S. Kohno

引用次数: 0

[Nocturnal pulmonary hypertension in patients with obstructive sleep apnea associated with daytime pulmonary hypertension]. [阻塞性睡眠呼吸暂停伴日间肺动脉高压患者的夜间肺动脉高压]。

Nihon Kyobu Shikkan Gakkai zasshi Pub Date : 1997-11-25 DOI: 10.11389/JJRS1963.35.1173

J. Kang, H. Kimura, M. Niijima, H. Edo, H. Sakabe, T. Shinozaki, S. Masuyama, O. Okada, K. Tatsumi, T. Kuriyama

{"title":"[Nocturnal pulmonary hypertension in patients with obstructive sleep apnea associated with daytime pulmonary hypertension].","authors":"J. Kang, H. Kimura, M. Niijima, H. Edo, H. Sakabe, T. Shinozaki, S. Masuyama, O. Okada, K. Tatsumi, T. Kuriyama","doi":"10.11389/JJRS1963.35.1173","DOIUrl":"https://doi.org/10.11389/JJRS1963.35.1173","url":null,"abstract":"We investigated the effect of state-specific changes associated with REM sleep on pulmonary artery pressure in patients with obstructive sleep apnea (OSAS). Six male patients with OSAS (age; 40 +/- 12 SD yrs, BMI; 39.0 +/- 8.6 kg/m2, AHI; 51.5 +/- 28.5) were examined throughout the night by polysomnography, while monitoring pulmonary artery pressure via right cardiac catheterization. All patients had pulmonary hypertension (PH) during periods of wakefulness, and their mean pulmonary artery pressure (PAPm) was 31.1 +/- 7.4 mmHg. PAPm was analyzed at two different points in each apneic episode. PAPbase was the baseline value when inspiratory effects during apnea were not elicited, and PAPpeak was the peak value observed just after the cessation of OSA. PAPpeak was higher in REM (56.3 +/- 12.4) than in NREM (41.4 +/- 6.9 mmHg; P < 0.01), and both values were significantly higher than those observed during periods of wakefulness. The magnitude of elevation of PAP (delta PAP; PAPpeak-PAPbase) in REM and NREM were 11.6 +/- 2.0 and 6.9 +/- 2.8 mmHg, respectively. Relative ratios in the response of PAP to a decrease in O2 desaturation (delta PAP/delta SpO2) showed almost the same value for REM (-0.57 +/- 0.27) and NREM sleep (-0.57 +/- 0.26 mmHg/%). The values of PAPm at SpO2 75% were significantly higher in REM than in NREM (48.7 +/- 11.2 vs. 41.6 +/- 6.2 mmHg). We conclude that transient pulmonary hypertension could be caused not only by hypoxia, but also by state-specific responses (which are unrelated to hypoxia) that occur during REM sleep.","PeriodicalId":19255,"journal":{"name":"Nihon Kyobu Shikkan Gakkai zasshi","volume":"11 6","pages":"1173-8"},"PeriodicalIF":0.0,"publicationDate":"1997-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91505499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

[A clinical study of 5 cases of acute eosinophilic pneumonia--the relationship between beginning to smoke and acute eosinophilic pneumonia]. 【急性嗜酸性粒细胞肺炎5例临床研究——开始吸烟与急性嗜酸性粒细胞肺炎的关系】。

Nihon Kyobu Shikkan Gakkai zasshi Pub Date : 1997-11-25 DOI: 10.11389/JJRS1963.35.1252

T. Kawamura, Y. Mochizuki, Y. Nakahara, T. Kimoto, S. Watanabe

引用次数: 7

[A case of humidifier lung characterized by histopathologic feature]. 【以组织病理学特征为特征的加湿器肺1例】。

Nihon Kyobu Shikkan Gakkai zasshi Pub Date : 1997-11-01

Y Nakaya, S Shiota, K Sakamoto, A Iwase, S Aoki, R Matsuoka, T Nagayama, M Saizyo, Y Kawabata

引用次数: 0

[A patient with allergic bronchopulmonary candidiasis showing a high serum level of soluble interleukin 2 receptors]. [过敏性支气管肺念珠菌病患者血清可溶性白细胞介素2受体水平高]。

Nihon Kyobu Shikkan Gakkai zasshi Pub Date : 1997-11-01

N Takabatake, S Seino, H Nakamura, H Tomoike

引用次数: 0

[The clinical utility of asbestos body counts in bronchoalveolar lavage fluid]. 支气管肺泡灌洗液中石棉体计数的临床应用

Nihon Kyobu Shikkan Gakkai zasshi Pub Date : 1997-11-01

K Takabe, Y Tsukada, T Shimizu, J Takagiwa, M Hirayama, M Nakayama, H Miura, H Akabane, S Takayama, S Aida

{"title":"[The clinical utility of asbestos body counts in bronchoalveolar lavage fluid].","authors":"K Takabe, Y Tsukada, T Shimizu, J Takagiwa, M Hirayama, M Nakayama, H Miura, H Akabane, S Takayama, S Aida","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>To assess the clinical utility of measuring the number of asbestos bodies (AB) present in bronchoalveolar lavage fluid (BALF), we counted the number of AB in BALF from 119 subjects using light microscopy. The results were analyzed according to occupational histories, radiological findings of asbestos-induced lung and pleural changes, and asbestos-related diseases. The 94 subjects in group 1 had a history of dust exposure, whereas group 2 subjects (n = 25) had no dust exposure. Group 1 was subdivided into subjects with obvious exposure to asbestos (group 1A, n = 61), and subjects with no known exposure to asbestos (group 1B, n = 33). The distribution of AB counts per ml of BALF (means +/- SEM) differed significantly between groups 1 and 2 (38.8 +/- 17.4 vs 0.06 +/- 0.04, p < 0.0001). The AB counts were significantly different between groups 1A and 1B (57.9 +/- 26.6 vs 3.4 +/- 1.2, p = 0.01). Subject, exposed to dust who had radiological evidence of pleural thickening had significantly higher AB counts than subjects in whom pleural thickening was absent (66.0 +/- 31.1 vs 5.1 +/- 4.2, p = 0.03). In group 1, the BALF was positive for AB in 7 of 14 patients with pulmonary fibrosis, 4 of 5 patients with lung cancer, all 6 patients with malignant mesothelioma, and all 4 patients with benign asbestos pleural effusion. We conclude that AB counts in BALF are useful for evaluating both the history of asbestos exposure in a population exposed to dust, as well as patients having asbestos-related diseases.</p>","PeriodicalId":19255,"journal":{"name":"Nihon Kyobu Shikkan Gakkai zasshi","volume":"35 11","pages":"1196-204"},"PeriodicalIF":0.0,"publicationDate":"1997-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20417498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0