Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology最新文献

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[Effect of L-carnosine on repeated social defeat stress-induced behavioral and neurochemical changes in mice]. [左旋肌肽对反复社交失败应激诱导小鼠行为和神经化学变化的影响]。
Masahiro Osawa, Yoshifumi Fujisawa, Hirotake Katsu, Shohei Yamamoto, Hideki Ono
{"title":"[Effect of L-carnosine on repeated social defeat stress-induced behavioral and neurochemical changes in mice].","authors":"Masahiro Osawa, Yoshifumi Fujisawa, Hirotake Katsu, Shohei Yamamoto, Hideki Ono","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":19250,"journal":{"name":"Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology","volume":"33 2","pages":"81-3"},"PeriodicalIF":0.0,"publicationDate":"2013-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32747136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Pituitary adenylate cyclase-activating polypeptide(PACAP) plays significant roles in mental function and neuronal development]. [垂体腺苷酸环化酶激活多肽(PACAP)在心理功能和神经元发育中起重要作用]。
Atsuko Hayata-Takano, Kaoru Seiriki, Minako Tajiri, Katsuya Ogata, Norito Shintani, Akimichi Baba, Hitoshi Hashimoto
{"title":"[Pituitary adenylate cyclase-activating polypeptide(PACAP) plays significant roles in mental function and neuronal development].","authors":"Atsuko Hayata-Takano, Kaoru Seiriki, Minako Tajiri, Katsuya Ogata, Norito Shintani, Akimichi Baba, Hitoshi Hashimoto","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":19250,"journal":{"name":"Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology","volume":"33 2","pages":"73-5"},"PeriodicalIF":0.0,"publicationDate":"2013-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32747140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Enhanced depressive-like behaviors after Toll-like receptor 7 stimulation in mice. toll样受体7刺激后小鼠抑郁样行为增强。
Yasunori Kubo, Yoshiki Yanagawa, Machiko Matsumoto, Sachiko Hiraide, Hiroko Togashi
{"title":"Enhanced depressive-like behaviors after Toll-like receptor 7 stimulation in mice.","authors":"Yasunori Kubo,&nbsp;Yoshiki Yanagawa,&nbsp;Machiko Matsumoto,&nbsp;Sachiko Hiraide,&nbsp;Hiroko Togashi","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Toll-like receptor (TLR) 7 recognizes viral single-stranded RNA and triggers anti-viral immune responses through the production of type I interferons (IFNs) IFN-alpha and IFN-beta. IFN-alpha is known to induce various psychiatric changes such as depressive symptoms; however, the correlation with TLR7 activation remains to be determined. In this study, we examined the effect of imiquimod, a TLR7 specific ligand, on depressive-like behaviors evaluated by the forced swim test (FST) and the tail suspension test (TST) in mice. Immobility durations were significantly prolonged in both FST and TST by 2 h after imiquimod treatment (50 microg/body, i.p.), indicating that TLR7 activation enhanced depressive-like behaviors in mice. In addition, imiquimod induced IFN-alpha mRNA expression in the hippocampus, whereas it prevented long-term potentiation in the Schaffer-CA1 pathway (i.e., hippocampal synaptic plasticity). Moreover, TLR7 mRNA expression in the hippocampus was higher than that in the whole brain. These findings suggest that TLR7 activation enhances depressive-like behaviors in mice, possibly through increasing IFN-alpha expression and altering synaptic plasticity in the hippocampus.</p>","PeriodicalId":19250,"journal":{"name":"Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology","volume":"33 2","pages":"41-7"},"PeriodicalIF":0.0,"publicationDate":"2013-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32540212","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Aripiprazol potentiates NGF-induced neurite outgrowth]. [阿立哌唑增强神经生长因子诱导的神经突生长]。
Tamaki Ishima, Masaomi Iyo, Kenji Hashimoto
{"title":"[Aripiprazol potentiates NGF-induced neurite outgrowth].","authors":"Tamaki Ishima,&nbsp;Masaomi Iyo,&nbsp;Kenji Hashimoto","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":19250,"journal":{"name":"Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology","volume":"33 2","pages":"59-60"},"PeriodicalIF":0.0,"publicationDate":"2013-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32747130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Personality dimensions in major depressive disorder predict cortisol reactivity to the combined dexamethasone/CRH test]. [重度抑郁症的人格维度预测皮质醇对地塞米松/CRH联合测试的反应]。
Hiroaki Hori, Toshiya Teraishi, D Sasayama, Kotaro Hattori, Miyako Hashikura, Teruhiko Higuchi, Hiroshi Kunugi
{"title":"[Personality dimensions in major depressive disorder predict cortisol reactivity to the combined dexamethasone/CRH test].","authors":"Hiroaki Hori,&nbsp;Toshiya Teraishi,&nbsp;D Sasayama,&nbsp;Kotaro Hattori,&nbsp;Miyako Hashikura,&nbsp;Teruhiko Higuchi,&nbsp;Hiroshi Kunugi","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":19250,"journal":{"name":"Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology","volume":"33 2","pages":"61-3"},"PeriodicalIF":0.0,"publicationDate":"2013-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32747131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Effectiveness of long-acting injectable risperidone for patients with treatment refractory schizophrenia]. 长效注射利培酮治疗难治性精神分裂症的疗效分析。
H Kimura, Nobuhisa Kanahara, Naoya Komatsu, Minoru Ishige, Katsumasa Muneoka, Masayuki Yoshimura, H Yamanaka, Tomotada Suzuki, Hideki Komatsu, Y Sekine, Hiroyuki Watanabe, Masaomi Iyo
{"title":"[Effectiveness of long-acting injectable risperidone for patients with treatment refractory schizophrenia].","authors":"H Kimura,&nbsp;Nobuhisa Kanahara,&nbsp;Naoya Komatsu,&nbsp;Minoru Ishige,&nbsp;Katsumasa Muneoka,&nbsp;Masayuki Yoshimura,&nbsp;H Yamanaka,&nbsp;Tomotada Suzuki,&nbsp;Hideki Komatsu,&nbsp;Y Sekine,&nbsp;Hiroyuki Watanabe,&nbsp;Masaomi Iyo","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":19250,"journal":{"name":"Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology","volume":"33 2","pages":"85-7"},"PeriodicalIF":0.0,"publicationDate":"2013-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32747137","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Cuprizone early deficits accompanied by specific glial activation implicate pathophysiological changes in schizophrenia]. [铜吡酮早期缺陷伴随特异性神经胶质激活与精神分裂症的病理生理变化有关]。
Tomoaki Tezuka, Makoto Tamura, Mari A Kondo, M Sakaue, Kinya Okada, Kana Takemoto, Atsushi Fukunari, Hiroshi Yasumatsu, Yasushi Kajii
{"title":"[Cuprizone early deficits accompanied by specific glial activation implicate pathophysiological changes in schizophrenia].","authors":"Tomoaki Tezuka,&nbsp;Makoto Tamura,&nbsp;Mari A Kondo,&nbsp;M Sakaue,&nbsp;Kinya Okada,&nbsp;Kana Takemoto,&nbsp;Atsushi Fukunari,&nbsp;Hiroshi Yasumatsu,&nbsp;Yasushi Kajii","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":19250,"journal":{"name":"Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology","volume":"33 2","pages":"65-6"},"PeriodicalIF":0.0,"publicationDate":"2013-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32747132","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of the genome wide supported NRGN gene on anterior cingulate morphologyin schizophrenia. 基因组广泛支持的NRGN基因对精神分裂症前扣带形态的影响。
Kazutaka Ohi, Ryota Hashimoto, Yuta Yasuda, Kiyotaka Nemoto, Takashi Ohnishi, Motoyuki Fukumoto, Hidenaga Yamamori, Satomi Umeda-Yano, Takeya Okada, Masao Iwase, Hiroaki Kazui, Masatoshi Takeda
{"title":"Impact of the genome wide supported NRGN gene on anterior cingulate morphologyin schizophrenia.","authors":"Kazutaka Ohi,&nbsp;Ryota Hashimoto,&nbsp;Yuta Yasuda,&nbsp;Kiyotaka Nemoto,&nbsp;Takashi Ohnishi,&nbsp;Motoyuki Fukumoto,&nbsp;Hidenaga Yamamori,&nbsp;Satomi Umeda-Yano,&nbsp;Takeya Okada,&nbsp;Masao Iwase,&nbsp;Hiroaki Kazui,&nbsp;Masatoshi Takeda","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":19250,"journal":{"name":"Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology","volume":"33 2","pages":"67-9"},"PeriodicalIF":0.0,"publicationDate":"2013-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32747133","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Anxiolytic effects of yokukansan and serotonin 5-HT1A receptors in rats]. [横参和5-HT1A受体对大鼠的抗焦虑作用]。
Taku Yamaguchi, Aki Tsujimatsu, Haruko Kumamoto, Tsuyoshi Izumi, Yu Omura, Takayuki Yoshida, Tsuneyuki Yamamoto, Mitsuhiro Yoshioka
{"title":"[Anxiolytic effects of yokukansan and serotonin 5-HT1A receptors in rats].","authors":"Taku Yamaguchi,&nbsp;Aki Tsujimatsu,&nbsp;Haruko Kumamoto,&nbsp;Tsuyoshi Izumi,&nbsp;Yu Omura,&nbsp;Takayuki Yoshida,&nbsp;Tsuneyuki Yamamoto,&nbsp;Mitsuhiro Yoshioka","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":19250,"journal":{"name":"Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology","volume":"33 2","pages":"71-2"},"PeriodicalIF":0.0,"publicationDate":"2013-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32747134","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Genome-wide association study identified susceptibility loci associated with nicotine dependence in a Japanese population]. [全基因组关联研究确定了日本人群中与尼古丁依赖相关的易感位点]。
Daisuke Nishizawa, Shinya Kasai, Jyunko Hasegawa, Naomi Sato, Fumihiko Tanioka, Haruhiko Sugimura, Kazutaka Ikeda
{"title":"[Genome-wide association study identified susceptibility loci associated with nicotine dependence in a Japanese population].","authors":"Daisuke Nishizawa,&nbsp;Shinya Kasai,&nbsp;Jyunko Hasegawa,&nbsp;Naomi Sato,&nbsp;Fumihiko Tanioka,&nbsp;Haruhiko Sugimura,&nbsp;Kazutaka Ikeda","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":19250,"journal":{"name":"Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology","volume":"33 2","pages":"77-9"},"PeriodicalIF":0.0,"publicationDate":"2013-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32747135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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