Nihon Shishubyo Gakkai Kaishi (Journal of the Japanese Society of Periodontology)最新文献

{"title":"Basic research on the potential therapeutic effect of endogenous anti-inflammatory molecule DEL-1 on periodontal disease","authors":"T. Maekawa","doi":"10.2329/perio.63.97","DOIUrl":"https://doi.org/10.2329/perio.63.97","url":null,"abstract":"","PeriodicalId":19230,"journal":{"name":"Nihon Shishubyo Gakkai Kaishi (Journal of the Japanese Society of Periodontology)","volume":"10 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86931008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of periodontal disease on the risk of development of cerebral infarction and myocardial infarction: a study using health insurance records","authors":"Takumi Ishihara, H. Matsuoka, T. Nagasawa, Y. Furuichi, M. Tsuji, I. Chiba","doi":"10.2329/perio.63.47","DOIUrl":"https://doi.org/10.2329/perio.63.47","url":null,"abstract":"","PeriodicalId":19230,"journal":{"name":"Nihon Shishubyo Gakkai Kaishi (Journal of the Japanese Society of Periodontology)","volume":"8 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73995957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fifteen-year treatment period in a patient with generalized aggressive periodontitis and lessons learned from the use of supportive periodontal therapy","authors":"K. Makigusa, Takuo Fukuoka, S. Itsuji","doi":"10.2329/perio.63.73","DOIUrl":"https://doi.org/10.2329/perio.63.73","url":null,"abstract":"","PeriodicalId":19230,"journal":{"name":"Nihon Shishubyo Gakkai Kaishi (Journal of the Japanese Society of Periodontology)","volume":"4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73713097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A case report of localized chronic periodontitis after 29 years of follow-up","authors":"K. Wakabayashi","doi":"10.2329/perio.63.66","DOIUrl":"https://doi.org/10.2329/perio.63.66","url":null,"abstract":"","PeriodicalId":19230,"journal":{"name":"Nihon Shishubyo Gakkai Kaishi (Journal of the Japanese Society of Periodontology)","volume":"8 9-10 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75002551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The basics and clinical management of calcium channel blocker-induced gingival overgrowth","authors":"Y. Ozaki, A. Yoshimura","doi":"10.2329/perio.63.37","DOIUrl":"https://doi.org/10.2329/perio.63.37","url":null,"abstract":"","PeriodicalId":19230,"journal":{"name":"Nihon Shishubyo Gakkai Kaishi (Journal of the Japanese Society of Periodontology)","volume":"22 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76734820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Data Science Education and the Construction of Clinical Databases in the Field of Medicine and Dentistry","authors":"A. Kinoshita","doi":"10.2329/perio.63.61","DOIUrl":"https://doi.org/10.2329/perio.63.61","url":null,"abstract":"ビッグデータに対応できるデータサイエンティスト 育成の必要性については,文部科学省,日本学術会議, 情報・システム研究機構からの報告書などにおいて強 く訴えられてきた。その後,AI戦略 2019の一環とし て,歯学部歯学科・口腔保健学科・歯科衛生学科等に おいても,2025年度までにすべての卒業生が数理・ データサイエンス・AIを理解し,具体的なデータに対 して利活用できる能力を持つことを目標として,取り 組みが推進されている。 日本では巨大な医療ビッグデータであるレセプト情 報が利活用されているが,貴重なデータを社会還元す る取組として,さらなる利活用と発展に大いに期待し たい。また,歯周治療目的で記録される診療データを 二次利用して行う後ろ向き研究も行われているが,各 研究者,各機関の努力のみに頼ることには限界がある。 今後は,日本歯周病学会として臨床データベースを構 築し,適切なルールの下で利活用できる体制が求めら れている。 本稿では,AI戦略 2019における歯学教育でのデー タサイエンス教育の取り組みと共に,日本歯周病学会 における臨床データベース委員会の非常にタイムリー な発足を紹介する。","PeriodicalId":19230,"journal":{"name":"Nihon Shishubyo Gakkai Kaishi (Journal of the Japanese Society of Periodontology)","volume":"39 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86093430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A case of chronic periodontitis with drug-induced gingival hyperplasia who improved with non-surgical periodontal treatment","authors":"Yukari Ebe, K. Sakoda, Y. Kawakami, Takako Shimotahira, Teruyo Namariyama, K. Noguchi","doi":"10.2329/perio.63.85","DOIUrl":"https://doi.org/10.2329/perio.63.85","url":null,"abstract":": Gingival hyperplasia is one of the well-known side effects of calcium channel blockers, which are often used for the treatment of hypertension. Gingival hyperplasia may induce malalignment of the teeth and aesthetic problems. Although the mechanisms of gingival hyperplasia are not yet clearly un-derstood, inflammatory conditions of the periodontal tissue caused by dental plaques are known to be in-volved in the pathogenesis of gingival hyperplasia. In general, a change of the antihypertensive drug to one without the side effect of gingival hyperplasia by the patientʼs attending physician, and thorough in-itial treatment, including plaque control and scaling and root planing are effective for the treatment of calcium channel blockers-induced gingival hyperplasia. Periodontal surgery may be performed, if neces-sary. Herein, we report the case of a 41-year-old male patient, a hypertensive under treatment with the calcium channel blocker amlodipine besilate Ⓡ , who was diagnosed as having gingival hyperplasia and chronic periodontitis (Stage III, Grade C). He presented with marked gingival enlargement and bleeding, mobility of the anterior maxillary teeth, and disordered teeth. We attempted periodontal infection control, including instructions on oral hygiene, and professional care, including scaling and root planing and professional mechanical tooth cleaning. After re-evaluation, persistence of deep pockets with a pocket depth of more than 4 mm at multiple sites was observed, although the gingival hyperplasia had almost completely resolved. We planned a flap operation, but we could not do it, because the patient was very busy with his career and did not provide informed consent. So, we repeated scaling and root planing, and used a local drug delivery system in order to eliminate periodontopathic microorganisms. Furthermore, we motivated the patient by repeatedly explaining the importance of plaque control, professional care, as well as blood pressure control. As a result, the periodontal tissue and dentition improved with non-surgical therapy.","PeriodicalId":19230,"journal":{"name":"Nihon Shishubyo Gakkai Kaishi (Journal of the Japanese Society of Periodontology)","volume":"09 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86174036","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Matrix vesicle-mediated mineralization and periodontal regeneration","authors":"Tomoaki Iwayama, S. Murakami","doi":"10.2329/perio.63.31","DOIUrl":"https://doi.org/10.2329/perio.63.31","url":null,"abstract":"石灰化(mineralization)は有機マトリックスへのリ ン酸カルシウム結晶の沈着であり,脊椎動物の生理的 及び病的な硬組織形成に普遍的な現象である。骨,軟 骨,象牙質,セメント質など間葉系組織由来の生体硬 組織の石灰化初期過程においては,硬組織形成細胞か ら細胞外マトリックスおよび 30-300 nmの基質小胞 (matrix vesicle)と呼ばれる膜性小器官が細胞外へと 分泌されることが必須である1‐3)。基質小胞にはカルシ ウムおよび無機リン酸のみならず,硬組織形成に必要 な酵素群や脂質が含まれ,硬組織が成熟していく過程 においては,細胞外マトリックスと基質小胞の相互作 用により,石灰化基質が形成され,硬組織の石灰化と 成熟が促進される。この一連の過程は基質小胞性石灰 化と呼ばれる。しかしながら,硬組織形成細胞中で基 質小胞がどのように形成され分泌されるかについて は,硬組織形成の基本的なメカニズムにも関わらず, 長年明確な結論が得られないままであった。ごく最近 になって,様々な新技術を用いた研究成果が次々と発 表され,基質小胞形成の過程が明らかになりつつある。 本稿では,これらの最新知見を紹介するとともに,歯 周組織において基質小胞性石灰化の果たす役割や,基 質小胞を用いた歯周組織再生療法の可能性について概 説したい。","PeriodicalId":19230,"journal":{"name":"Nihon Shishubyo Gakkai Kaishi (Journal of the Japanese Society of Periodontology)","volume":"91 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74613626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Expression of Cannabinoid Receptor GPR55 in Human Gingival Fibroblasts and Anti-inflammatory Effects of Cannabidiol via GPR55","authors":"Saki Mishiro, Hiroko Igarashi-Takeuchi, Y. Numabe","doi":"10.2329/PERIO.63.11","DOIUrl":"https://doi.org/10.2329/PERIO.63.11","url":null,"abstract":": Cannabidiol (CBD) in cannabis has an anti-inflammatory effect, and its receptor, G protein-coupled receptor 55 (GPR55), has been suggested to be involved in the regulation of inflammation. Here, we investigated GPR55 expression in human gingival fibroblasts (HGFs) and anti-inflammatory effects of CBD via GPR55. GPR55 expression and localization were confirmed in control, LPS-stimulated (LPS), CBD-treated and LPS-stimulated (CBD ＋ LPS), and CBD-treated (CBD) groups. We also compared interleukin (IL)-6 and IL-8 protein production in each group. GPR55 expression levels were significantly reduced in the LPS and CBD ＋ LPS groups (p ＜ 0.05) compared to control and CBD groups, and GPR55 protein was found diffusely in the cytoplasm of HGFs in all groups. In addition, IL-6 and IL-8 production was significantly reduced in non-knockdown HGFs in the CBD ＋ LPS group compared to the LPS group (p ＜ 0.05). By contrast, in GPR55-knockdown HGFs, there was a significant increase in IL-6 and IL-8 production in the LPS and CBD ＋ LPS groups compared with the control groups (p ＜ 0.05), but there was no significant difference in IL-6 and IL-8 production in GPR 55-knockdown HGFs between the LPS and CBD ＋ LPS groups. In this study, we confirmed the homeostatic expression of GPR55 in HGFs and its tendency to decrease in expression during inflammation. It was also shown that part of an anti-inflammatory effect by CBD may be mediated by GPR55.","PeriodicalId":19230,"journal":{"name":"Nihon Shishubyo Gakkai Kaishi (Journal of the Japanese Society of Periodontology)","volume":"40 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90603632","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of local immune response against periotontopathogenic bacteria in periodontal tissue to systemic disease","authors":"K. Ouhara","doi":"10.2329/perio.62.183","DOIUrl":"https://doi.org/10.2329/perio.62.183","url":null,"abstract":"","PeriodicalId":19230,"journal":{"name":"Nihon Shishubyo Gakkai Kaishi (Journal of the Japanese Society of Periodontology)","volume":"85 1","pages":"183-192"},"PeriodicalIF":0.0,"publicationDate":"2020-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75824340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}