{"title":"Multicenter Experience and Diameter Analysis of the Low-profile Visualized Intraluminal Support EVO™ in the Treatment of Unruptured Intracranial Aneurysms.","authors":"Kazutaka Uchida, Shinichi Yoshimura, Manabu Shirakawa, Hitoshi Hasegawa, Akira Ishii, Masakazu Okawa, Hirotoshi Imamura, Toshiyuki Fujinaka, Kenji Sugiu, Yuji Matsumaru, Nobuyuki Sakai, Shigeru Miyachi","doi":"10.2176/jns-nmc.2026-0016","DOIUrl":"https://doi.org/10.2176/jns-nmc.2026-0016","url":null,"abstract":"<p><p>The Low-Profile Visualized Intraluminal Support EVO stent enables full fluoroscopic visualization and provides higher metal coverage than conventional devices used to assist coil embolization of wide-neck unruptured intracranial aneurysms. We conducted a prospective multicenter clinical trial to assess its efficacy and safety in stent-assisted coil embolization. A total of 41 patients were enrolled across 6 centers. The primary endpoint of clinical success was achieved in 39 of 40 implanted cases (97.5%; 95% confidence interval, 86.8%-99.9%). These findings demonstrate the efficacy and safety of Low-Profile Visualized Intraluminal Support EVO as an assist stent for wide-neck aneurysms. Given that concerns remain regarding thrombotic risk with small-diameter devices (2.5-3.0 mm), a subgroup analysis comparing the results of small-diameter Low-Profile Visualized Intraluminal Support EVO (2.5-3.0 mm) versus those of larger Low-Profile Visualized Intraluminal Support EVO (3.5-4.0 mm) was conducted. Fifteen cases were included in the small-diameter group, and 25 were included in the comparative group. Ischemic events occurred in 1 of 15 (6.7%) patients in the small-diameter group and in 2 of 25 (8.0%) patients in the larger-diameter group, with no statistically significant difference between the 2 groups, and all events were transient or asymptomatic. At 6 months, 13 of 14 (92.9%) patients in the small-diameter group achieved complete occlusion (Raymond-Roy Class I, core laboratory adjudicated). Overall, small-diameter Low-Profile Visualized Intraluminal Support EVO did not confer a significantly higher risk of ischemic complications compared with larger-diameter devices and demonstrated favorable therapeutic potential for the treatment of wide-neck aneurysms. Trial registration: jRCT2042230075.</p>","PeriodicalId":19225,"journal":{"name":"Neurologia medico-chirurgica","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2026-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147777262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"High Parietal Endoscopic Approach for Thalamic Hemorrhage: Technical Nuances and Preliminary Outcomes.","authors":"Yuri Yamagiwa, Toshikazu Kimura, Shunsuke Ichi","doi":"10.2176/jns-nmc.2025-0239","DOIUrl":"https://doi.org/10.2176/jns-nmc.2025-0239","url":null,"abstract":"<p><p>We assessed the technical utility and preliminary outcomes of endoscopic hematoma evacuation via the high parietal approach for thalamic hemorrhage with intraventricular extension (intraventricular hemorrhage) by retrospectively reviewing 270 patients treated between April 1, 2006, and July 31, 2024. Prior to 2017, the primary treatment was external ventricular drainage, and in selected patients with thick intraventricular hematoma, an anterior endoscopic approach was used primarily for intraventricular hemorrhage removal. Since April 2017, the high parietal approach technique has been used for the simultaneous removal of both thalamic hematoma and intraventricular hemorrhage in 21 patients. The high parietal approach group showed a median hematoma evacuation rate of 92.2% and, compared with the external ventricular drainage-only group, a significantly shorter duration of ventricular drainage and a lower incidence of tracheostomy. No cases of surgical site infection or meningitis occurred in the high parietal approach group. Complications included 1 death due to postoperative rebleeding and another due to worsening pneumonia and heart failure. Secondary hydrocephalus requiring shunt placement was observed only in the external ventricular drainage group. Although not statistically significant, the high parietal approach group showed a higher rate of early resumption of oral intake. These findings suggest that endoscopic evacuation via the high parietal approach is a minimally invasive technique that achieves high hematoma removal rates, facilitates early postoperative recovery, and may reduce complications such as prolonged drainage, tracheostomy, and hydrocephalus in selected patients with large thalamic hemorrhage and intraventricular hemorrhage.</p>","PeriodicalId":19225,"journal":{"name":"Neurologia medico-chirurgica","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2026-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147777264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Risk of Cognitive Decline in Professional Soccer Players after Repetitive Subconcussive Impacts: A Systematic Review and Meta-analysis.","authors":"Tomasz Tykocki","doi":"10.2176/jns-nmc.2025-0451","DOIUrl":"https://doi.org/10.2176/jns-nmc.2025-0451","url":null,"abstract":"<p><p>Repetitive soccer heading has been implicated as a potential source of cumulative subconcussive brain injury, yet the magnitude and consistency of its cognitive effects remain incompletely defined. We conducted a systematic review and meta-analysis to quantify global and domain-specific cognitive outcomes associated with repetitive heading exposure. Following Preferred Reporting Items for Systematic Reviews and Meta-Analyses 2020 guidelines, PubMed/MEDLINE, Scopus, and Web of Science were searched through December 2025. Of 2,846 identified records, 46 studies met the inclusion criteria, and 28 provided standardized cognitive data suitable for quantitative synthesis. Effect sizes (Hedges g, Fisher z) were transformed into log odds ratios and pooled using DerSimonian-Laird random-effects models. Heterogeneity was assessed using Q, I<sup>2</sup>, and H<sup>2</sup> statistics, and publication bias was evaluated with funnel plots, Egger regression, and trim-and-fill procedures, alongside leave-one-out influence analyses. Across 28 independent author-level datasets, repetitive heading was associated with significantly increased odds of global cognitive underperformance (odds ratio 1.67; 95% confidence interval 1.61-1.72), with moderate heterogeneity (I<sup>2</sup> ≈ 34%). Trim-and-fill adjustment yielded a modestly attenuated but still significant estimate (odds ratio 1.49). Domain-level analyses demonstrated consistent impairments across visuospatial ability (odds ratio 1.49), verbal memory (odds ratio 1.62), attention (odds ratio 1.71), processing speed (odds ratio 1.64), executive function (odds ratio 1.86), and composite cognition (odds ratio 1.58). Confidence intervals were narrow, once, and the effect directionality was uniform across domains. These findings indicate that repetitive soccer heading is associated with robust, reproducible cognitive deficits across multiple cognitive systems, supporting cumulative subconcussive exposure as an independent risk factor for measurable cognitive decline.</p>","PeriodicalId":19225,"journal":{"name":"Neurologia medico-chirurgica","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2026-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147777308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shunsuke Kawamoto, Go Ikeda, Shunsuke Fukaya, Kanae Okunuki, Hiroyoshi Akutsu
{"title":"Long-term Cerebrovascular Risk after Microsurgical Clipping of Unruptured Anterior Circulation Aneurysms: Low Subarachnoid Hemorrhage Incidence and Persistent Stroke Susceptibility over 7,600 Patient-years.","authors":"Shunsuke Kawamoto, Go Ikeda, Shunsuke Fukaya, Kanae Okunuki, Hiroyoshi Akutsu","doi":"10.2176/jns-nmc.2026-0003","DOIUrl":"https://doi.org/10.2176/jns-nmc.2026-0003","url":null,"abstract":"<p><p>Microsurgical clipping is an established treatment for unruptured intracranial aneurysms; however, long-term cerebrovascular outcomes beyond aneurysm obliteration remain incompletely characterized in surgically treated patients, particularly regarding non-hemorrhagic cerebrovascular events. We retrospectively analyzed 930 patients (990 procedures; 655 females, 275 males; mean age, 62.8 years) with asymptomatic anterior circulation unruptured intracranial aneurysms treated between 2003 and 2025, with a total follow-up of 7,638 patient-years (median, 8.3 years). The primary endpoint was postoperative subarachnoid hemorrhage, and secondary endpoints included all-stroke events and all-cause mortality. Incidence rates with 95% confidence intervals were calculated, and rate ratios versus natural-history cohorts (Unruptured Cerebral Aneurysm Study and Small Unruptured Intracranial Aneurysm Verification Study) and standardized incidence ratios versus the general population were computed using Poisson methods. Ten subarachnoid hemorrhage events occurred (1.31 per 1,000 patient-years; 95% confidence interval, 0.63-2.41), with most arising from untreated or de novo aneurysms; only 1 case originated from a previously clipped site, demonstrating durable protection at treated sites. Subarachnoid hemorrhage incidence was substantially lower than that reported in natural-history cohorts of conservatively managed unruptured intracranial aneurysms. In contrast, age-adjusted all-stroke incidence remained approximately 2-fold higher than in the general population (standardized incidence ratio 2.11; 95% confidence interval, 1.50-2.90; p < 0.001), driven predominantly by ischemic events. These findings indicate that microsurgical clipping effectively reduces the risk of subarachnoid hemorrhage from treated aneurysms, whereas overall cerebrovascular risk remains elevated, reflecting persistent systemic vascular vulnerability rather than failure of local treatment. Long-term follow-up incorporating appropriate imaging surveillance and intensive management of modifiable vascular risk factors is therefore essential to optimize outcomes in this patient population.</p>","PeriodicalId":19225,"journal":{"name":"Neurologia medico-chirurgica","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2026-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147777337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dai Uzuki, Mudathir Bakhit, Ryo Hiruta, Masazumi Fujii
{"title":"Detailed Examination of the Sulci and Gyri Surrounding Broca's Area: A Comparative Morphological Study of Japanese and North American Populations.","authors":"Dai Uzuki, Mudathir Bakhit, Ryo Hiruta, Masazumi Fujii","doi":"10.2176/jns-nmc.2025-0203","DOIUrl":"https://doi.org/10.2176/jns-nmc.2025-0203","url":null,"abstract":"<p><p>The inferior frontal cortex (IFC), which includes Broca's area, is a frequent target in neurosurgical procedures, yet its sulcal landmarks remain under-characterized across populations. We evaluated 7 IFC sulci-the inferior precentral sulcus (prcs-i), inferior frontal sulcus (ifs), triangular sulcus (ts), diagonal sulcus (ds), pretriangular sulcus (prts), and the ascending (aaLF) and horizontal (haLF) anterior rami of the lateral fissure-using high-resolution magnetic resonance imaging (MRI) data from 40 Japanese and 40 North American White adults, supplemented by 9 cadaveric hemispheres. Sulci were manually labeled in FreeSurfer, quantified for surface area and depth, and analyzed for interhemispheric and inter-racial differences. Maximum probability maps (MPMs) were projected against meta-analytic functional MRI maps to evaluate structure-function relationships. The prcs-i and haLF were universally present, whereas the ds showed the lowest incidence (≈55%-60% left, ≈75% right), with variability across studies partly explained by misclassification with the aaLF. The prts was also infrequent and highly variable, whereas the ts, although structurally diverse, was nearly universal. Quantitative analyses confirmed the aaLF was significantly deeper than the ds (p < 0.0001), providing an objective criterion for differentiation. Functionally, high-frequency sulci (aaLF, haLF, ifs, prcs-i, ts) aligned with reliable activation patterns for verbal fluency, semantics, and syntax, whereas the ds frequently coincided with hotspots despite inconsistent presence. These findings can offer anatomical insights that may guide future clinical research on the frontal language area.</p>","PeriodicalId":19225,"journal":{"name":"Neurologia medico-chirurgica","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2026-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147777345","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Development of Diagnostic Support Software for Phase Estimation of Intracerebral Hemorrhage Using Multi-sequence Magnetic Resonance Imaging.","authors":"Masayoshi Mori, Takanori Masuda, Kohei Sugimoto, Toshinori Matsushige, Masahiro Hosogai, Shinichiro Oku, Masaki Ishikawa, Hiroki Takahashi, Kenta Kaneyoshi, Mikako Takeuchi, Takashi Fujimoto, Chiaki Ono","doi":"10.2176/jns-nmc.2025-0277","DOIUrl":"10.2176/jns-nmc.2025-0277","url":null,"abstract":"<p><p>Intracerebral hemorrhage is a severe type of stroke with high morbidity and mortality. Accurate assessment of hemorrhage phase is essential for determining treatment strategies, but magnetic resonance imaging evaluation remains subjective and lacks standardized criteria. This study aimed to create an objective method for estimating the phase of intracerebral hemorrhage using multi-sequence magnetic resonance imaging with 6 sequences: T1-weighted imaging, T2-weighted imaging, diffusion-weighted imaging, apparent diffusion coefficient map, fluid-attenuated inversion recovery, and T2 star-weighted magnetic resonance angiography. We retrospectively analyzed 56 patients with intracerebral hemorrhage. Magnetic resonance images used in this study were acquired using GE 1.5T scanners. Relative signal intensities were calculated using the pons as a reference, and a hemorrhage map was generated using color-coding pixels according to the 5 hemorrhage phases. Seven observers performed visual evaluations under 2 conditions: conventional image sets and hemorrhage maps. Diagnostic performance was assessed using precision-recall curves, average precision, and mean average precision. Interobserver agreement was evaluated using Fleiss' κ coefficient. The mean average precision of visual evaluation with the hemorrhage map was significantly higher than that of visual evaluation with original images (0.81 vs. 0.57, p < 0.01). Visual evaluation with hemorrhage map achieved \"Almost perfect agreement\" (κ = 0.85), whereas visual evaluation with original images demonstrated only \"Slight agreement\" (κ = 0.06). This study developed a novel diagnostic support method for estimating intracerebral hemorrhage phase using multi-sequence magnetic resonance imaging. By visualizing relative signal intensity as a color-coded hemorrhage map, the proposed method significantly improved both diagnostic accuracy and interobserver agreement compared with conventional visual evaluation.</p>","PeriodicalId":19225,"journal":{"name":"Neurologia medico-chirurgica","volume":" ","pages":"216-223"},"PeriodicalIF":2.3,"publicationDate":"2026-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146220325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Warfarin-associated Chronic Subdural Hematomas May Exhibit a Shorter Post-traumatic Interval: An Observational Study.","authors":"Vaner Köksal, Recai Engin, Cem Demirel, Erhan Abanoz, Dursun Türköz, Tayfun Çakir","doi":"10.2176/jns-nmc.2025-0331","DOIUrl":"10.2176/jns-nmc.2025-0331","url":null,"abstract":"<p><p>Chronic subdural hematoma remains one of the most common neurosurgical conditions in elderly patients, with anticoagulant use recognized as a major risk factor. This retrospective observational study investigated whether warfarin influences the temporal relationship between minor head trauma and the onset of neurological symptoms, here defined as the post-traumatic interval. Among 373 surgically treated patients between 2016 and 2022, only 126 with reliable trauma histories were included to minimize recall bias. Patients were stratified according to antithrombotic use (warfarin, aspirin, warfarin plus aspirin, or none). The median the post-traumatic interval was significantly shorter in the warfarin group compared with controls and aspirin users, suggesting that anticoagulation accelerates clinical manifestation. Warfarin was also associated with higher rates of bilateral hematomas, cerebral herniation, and poorer short-term functional outcomes, although most patients improved after surgical evacuation. The strict inclusion process reduced the sample size but increased the validity of the post-traumatic interval assessment, and the concept of the post-traumatic interval itself is not yet a validated clinical parameter. These findings raise the hypothesis that warfarin may shorten the latent period of chronic subdural hematoma through mechanisms of rebleeding and accelerated hematoma remodeling. Recognition of this effect could help clinicians anticipate earlier neurological deterioration in anticoagulated patients, underscoring the importance of early vigilance and imaging after seemingly trivial trauma in this high-risk population.</p>","PeriodicalId":19225,"journal":{"name":"Neurologia medico-chirurgica","volume":" ","pages":"248-255"},"PeriodicalIF":2.3,"publicationDate":"2026-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147326583","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Brain Lesions Associated with Human Immunodeficiency Virus Infection in the Antiretroviral Therapy Era: A Single-center Experience in Japan.","authors":"Yosuke Fujimi, Katsunori Asai, Dai Watanabe, Tomoko Uehira, Yonehiro Kanemura, Nobuyuki Izutsu, Shuhei Kawabata, Hideki Kuroda, Masayoshi Kida, Mao Kanechi, Keiko Okusu, Yoshitsugu Nishijima, Takaaki Matsumoto, Toshiyuki Fujinaka","doi":"10.2176/jns-nmc.2025-0348","DOIUrl":"10.2176/jns-nmc.2025-0348","url":null,"abstract":"<p><p>This study aimed to describe the clinical characteristics of patients with human immunodeficiency virus-related brain lesions who underwent neurosurgical procedures in the antiretroviral therapy era. We retrospectively analyzed 27 neurosurgical procedures in 23 patients with human immunodeficiency virus from January 2013 to December 2023. The mean ages at human immunodeficiency virus diagnosis and surgery were 46.2 ± 12.7 years and 50.8 ± 13.8 years, respectively. At human immunodeficiency virus diagnosis, 18 patients (78.3%) met the criteria for acquired immunodeficiency syndrome, and 11 (47.8%) had a cluster of differentiation 4 count of <50 cells/μL. In total, 16 lesions were diagnosed as an acquired immunodeficiency syndrome-defining illness, including primary central nervous system lymphoma (n = 10), and 11 were diagnosed as a non-acquired immunodeficiency syndrome-defining illness. The mean viral load at surgery was higher in the acquired immunodeficiency syndrome-defining illness group (6.1 ± 11.9 × 10<sup>5</sup> copies/mL) than in the non-acquired immunodeficiency syndrome-defining illness group (1.2 ± 2.8 × 10<sup>5</sup> copies/mL, p = 0.009). The time from human immunodeficiency virus diagnosis to surgery was shorter in the acquired immunodeficiency syndrome-defining illness group (7.0 ± 25.2 months vs. 50.6 ± 63.8 months, p = 0.003). A significantly greater number of patients with non-acquired immunodeficiency syndrome-defining illness than acquired immunodeficiency syndrome-defining illness had been treated with antiretroviral therapy for >3 months (72.7% vs. 12.5%, respectively; p = 0.003). The introduction of antiretroviral therapy appears to have contributed to a decrease in brain lesions diagnosed as acquired immunodeficiency syndrome-defining illness, with a corresponding increase in those diagnosed as non-acquired immunodeficiency syndrome-defining illness.</p>","PeriodicalId":19225,"journal":{"name":"Neurologia medico-chirurgica","volume":" ","pages":"233-239"},"PeriodicalIF":2.3,"publicationDate":"2026-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146220307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Transition from Subdural Electrocorticography to Stereo-electroencephalography in Presurgical Evaluation of Epilepsy: Single-institutional Experience.","authors":"Yosuke Okazaki, Takahiro Hayashi, Keiya Iijima, Yuiko Kimura, Yuu Kaneko, Shota Tanaka, Masaki Iwasaki","doi":"10.2176/jns-nmc.2025-0304","DOIUrl":"10.2176/jns-nmc.2025-0304","url":null,"abstract":"<p><p>Stereo-electroencephalography has recently gained attention as a less invasive and effective technique for presurgical evaluation in patients with drug-resistant epilepsy. Several studies have reported favorable outcomes when compared to conventional subdural electrode implantation. This study aimed to compare the target regions, complications, additional surgeries, and surgical outcomes between stereo-electroencephalography and subdural electrode implantation. A retrospective review was conducted on 83 consecutive patients who underwent intracranial electrode implantation between 2018 and 2024. Clinical variables were compared between the subdural electrode implantation (n = 41) and stereo-electroencephalography (n = 42) groups. In the stereo-electroencephalography group, 28 cases (66.7%) were implanted in the insular gyrus as the deep area, which was significantly different from the subdural electrode implantation group (8 cases, 19.5%). Resective surgery was performed in 39 subdural electrode implantation cases. In the stereo-electroencephalography group, 20 patients underwent resection, 14 received thermocoagulation, 5 were scheduled for surgery, and 3 were not eligible for surgery because the epileptogenic zone could not be identified. Intracranial hemorrhage occurred in 3 cases in each group. Two subdural electrode implantation cases were symptomatic and required reoperation, whereas all stereo-electroencephalography-related hemorrhages were asymptomatic. One year after surgery, seizure freedom was achieved in 57.9% (22 of 38 cases) of subdural electrode implantation and 64.0% (16 of 22 cases) of stereo-electroencephalography patients (p = 0.606). Seizure outcomes and complication rates were similar between stereo-electroencephalography and subdural electrode implantation, with fewer serious complications in the stereo-electroencephalography group. Stereo-electroencephalography was more frequently used in cases involving deep lesions or prior subdural implantation, highlighting its utility in technically challenging cases.</p>","PeriodicalId":19225,"journal":{"name":"Neurologia medico-chirurgica","volume":" ","pages":"240-247"},"PeriodicalIF":2.3,"publicationDate":"2026-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147326639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Letter: Real-world Experience of Embolization for Intracranial Tumors in Japan: Analysis of 2,756 Cases from the Japanese Registry of NeuroEndovascular Therapy 4.","authors":"Soichi Oya","doi":"10.2176/jns-nmc.2025-0314","DOIUrl":"10.2176/jns-nmc.2025-0314","url":null,"abstract":"","PeriodicalId":19225,"journal":{"name":"Neurologia medico-chirurgica","volume":" ","pages":"256"},"PeriodicalIF":2.3,"publicationDate":"2026-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146220317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}