Nigerian Journal of Basic and Clinical Sciences最新文献

{"title":"Facial heights as predictors of occlusal vertical dimension in a Nigerian population: A pilot study","authors":"T. Adeyemi, Chikao Oguchi, P. Idon, Y. Adeyemo, Sabeer Iya, O. Ikusika","doi":"10.4103/njbcs.njbcs_21_22","DOIUrl":"https://doi.org/10.4103/njbcs.njbcs_21_22","url":null,"abstract":"Context: Facial height measurements may aid in predicting occlusal vertical dimension (OVD). Aim: To compare facial third measurements among individuals with healthy occlusions for a predictive ratio for occlusal vertical dimension determination. Setting and Design: A cross-sectional prospective observational study at the Dental Clinic of Aminu Kano Teaching Hospital. Sampling was purposive. Materials and Methods: A digital caliper was used to measure the upper facial height (UFH), the midfacial height (MFH), and the lower facial height (LFH) of 103 participants. Statistical Analysis Used: The data collected were analyzed with IBM Statistical Package for the Social Sciences (SPSS) version 25. The level of statistical significance was set at P ≤ 0.05. Results: There were 69 male (67%) and 34 female (33%) members in the cohort analyzed. The ages of the participants ranged from 18 to 58 years, with a mean age of 27.3 ± 6.8 years. The UFH ranged from 60 to 110 mm with a mean value of 82.2 ± 9.8 mm. The MFH ranged from 55 to 100 mm with mean value of 74.6 ± 9.9 mm. The LFH ranged from 60 to 90 mm with a mean of 73.2 ± 7.4 mm. There was a significantly positive correlation between UFH and LFH (r = 0.22). This was similar to that of MFH and LFH (r = 0.61). The best fit model equation for the prediction of LFH was found to be LFH = 31.495 + (0.442 × MFH). Conclusions: This study found MFH to be a predictable factor for LFH estimation which can be used for OVD determination.","PeriodicalId":19224,"journal":{"name":"Nigerian Journal of Basic and Clinical Sciences","volume":"35 1","pages":"107 - 112"},"PeriodicalIF":0.1,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89451630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A single-center detection of adult patients with advanced periodontal disease using surgical assessment and cone-beam computed tomography","authors":"Ajay Chandran, M. Das, K. Gufran, M. Khan, A. Alqahtani, M. Chikkanna, C. Swarnalatha, J. Babu, A. Nayyar","doi":"10.4103/njbcs.njbcs_66_21","DOIUrl":"https://doi.org/10.4103/njbcs.njbcs_66_21","url":null,"abstract":"Context: One of the major limitations of conventional radiological procedures is the presence of considerable overlapping and lack of clear, three-dimensional information. Cone-beam computed tomography (CBCT) has emerged as an effective imaging modality in such situations offering high-quality images and lower radiation exposure to patients. Aim: The aim of the present study was to assess the role of CBCT in the detection of intra-bony defects in patients with advanced periodontal disease. Settings and Design: The present study was designed as a prospective, observational study wherein patients aged between 35–55 years with advanced periodontal disease who were indicated for periodontal treatment in form of periodontal surgeries were selected from the outpatient department (OPD) based on defined inclusion and exclusion criteria. Materials and Methods: Sixty patients with chronic periodontitis with 12 teeth each including 6 anterior and 6 posterior teeth were selected for making measurements pre- and peri-operatively while bone defects were measured first with the help of CBCT software installed in an individualized system devised to be used for storing and analyzing CBCT images and then, during surgical intervention using standardized UNC-15 periodontal probe and compared. Statistical Analysis Used: Statistical analysis was performed using SPSS version 18.0 (SPSS Inc., Chicago, IL, USA). The measurements obtained with the help of CBCT software installed in the personalized system and those obtained on surgical exploration were compared in each anterior and posterior tooth with the help of paired-sample t-test while Pearson's correlation(r) was used to test the correlation between the observed values. The level of statistical significance was set at P < 0.05. Results: The results were found to be highly significant both in terms of statistical (P-value) and clinical (r) significance for various sites in the anterior and posterior teeth in all instances. Conclusions: From the observations made from the present study, it could be concluded that CBCT provided highly precise assessment of bone topography equivalent to the judgment obtained during surgical exposure at the sites of interest preoperatively, which helped in assessing the exact type and depth of defect present and helped in optimizing surgical treatment planning.","PeriodicalId":19224,"journal":{"name":"Nigerian Journal of Basic and Clinical Sciences","volume":"64 1","pages":"101 - 106"},"PeriodicalIF":0.1,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73867575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Factors associated with 12-month psycho-active substance use among police officers in Kano Metropolis, Kano, Nigeria","authors":"Kefas J. Kwaghe, F. Tsiga-Ahmed, T. Amole, M. Bello, R. Jalo, A. Kwaku, U. Ibrahim, Hadiza M. Abdullahi, A. Aminu","doi":"10.4103/njbcs.njbcs_56_21","DOIUrl":"https://doi.org/10.4103/njbcs.njbcs_56_21","url":null,"abstract":"Context: Substance use is a widely recognized and pressing public health issue with grave consequences. It is important to prevent mishaps of substance use among the police. Aim: This study assessed the prevalence and factors associated with 12-month psycho-active substance use among police officers in Kano, Nigeria. Settings and Design: A cross-sectional study was conducted among police officers serving within metropolitan Kano. Methods and Materials: Pre-validated, adapted, semi-structured questionnaires were used to collect socio-demographic, work-related data and information on psycho-active substance use. Statistical Analysis Used: Multi-variate logistic regression modeling was used to determine factors associated with psycho-active substance use. All analyses were performed using STATA/IC 15.0. Results: Among 275 officers with a mean age of 35.1 ± 7.7 years, 14.9% (n = 41) recently used one or more psycho-active substances within the last 12 months, and tobacco was the most commonly used (n = 41, 100%). A lower likelihood of substance use was found among officers who were in their fifth decade of life (aOR = 0.29, 95% CI: 0.10–0.55), had tertiary education (aOR = 0.32, 95% CI: 0.14–0.77), were inspectors (aOR = 0.15, 95% CI: 0.16–0.61), were at the rank of ASP or higher (aOR = 0.58, 95% CI: 0.30–0.78), and had been in service between 16 and 20 years (aOR = 0.23, 95% CI: 0.11–0.65). Conclusion: Demographic and work-related characteristics influence the use of psycho-active substances among police officers in Nigeria. There is a need to revamp existing substance monitoring strategies to avoid catastrophic consequences of substance use among the society's gatekeepers.","PeriodicalId":19224,"journal":{"name":"Nigerian Journal of Basic and Clinical Sciences","volume":"137 1","pages":"132 - 138"},"PeriodicalIF":0.1,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86484449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sub-acute toxicity studies of the hypocotyl extract of Borassus Aethiopum on hepato-renal functions, and haematological indices in wistar rats","authors":"M. Ramalan, Adamu Shuaibu, U. Abdussalam, A. Yaro","doi":"10.4103/njbcs.njbcs_8_22","DOIUrl":"https://doi.org/10.4103/njbcs.njbcs_8_22","url":null,"abstract":"Context: Borassus aethiopum is a tropical plant found in the most parts of West Africa. The fruits, sap, and hypocotyl are used for nutritional purposes and in traditional herbal medicine for the treatment of various diseases and infertility. Despite its widespread use, there is insufficient data on its safety profile. Aim: This study is aimed to evaluate the safety of the plant on the hematological indices, liver, and kidney function. Materials and Methods: Twenty Adult male Wistar rats were divided into 4 groups of 5 rats each and were orally administered with different doses of the extract (250, 500, and 1000 mg/kg) and 1 ml of distilled water, respectively, for 28 days. The median lethal dose (LD50) was determined using Lorke's method. The hematological indices, liver and kidney functions of the animals were assessed using standard procedures with the aid of an autoanalyzer. Result: The oral median lethal dose (LD50) was determined to be greater than 5000 mg/kg. No mortality was recorded in the rats after 28 days of daily treatment. With sub-chronic administration, no adverse toxicological effect was observed. There was also no significant difference observed in the hematological, liver, and kidney function parameters between the control group and extract-treated groups. Conclusion: The present study shows that methanol hypocotyl extract of Borassus aethiopum is pre-clinically safe in Wistar rats at the doses tested and may not likely produce any toxic effect on prolonged administration.","PeriodicalId":19224,"journal":{"name":"Nigerian Journal of Basic and Clinical Sciences","volume":"22 1","pages":"145 - 150"},"PeriodicalIF":0.1,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84645421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Successful application of Maggot Debridement Therapy (MDT) on a Fournier's gangrene: First case report in Nigeria","authors":"M. Yusuf, B. Ibrahim, A. Abubakar, S. Aji, F. Abubakar, M. Abubakar, A. Sheshe, Shamsuddeen Muhammad, Mustapha Ibrahim, U. Bello, M. Abbas, A. Muhammad, K. Adamu","doi":"10.4103/njbcs.njbcs_42_22","DOIUrl":"https://doi.org/10.4103/njbcs.njbcs_42_22","url":null,"abstract":"Fournier's gangrene is a rapidly progressing soft tissue infection and a urological emergency affecting the external genitalia or the perineum. Maggot debridement therapy (MDT) has resurfaced as a result of the steep rise in the emergence of antibiotic-resistant strains of pathogenic bacteria and the need for an effective non-surgical method for wound debridement. This case study reports on a 66-year-old known diabetic who presented to our facility with complaints of scrotal swelling and multiple foul-smelling ulcers around the genital area. There was associated history of pain and fever for twelve-day duration. Sterile first instar larvae of L. sericata were applied using the free-ranged method. Significant decrease in the peri-wound oedema, rapid epithelization and increased vascularity were observed in the patient after the therapy. Maggot debridement therapy was successfully used in the debridement of Fournier's gangrene in Nigeria for the first time, and the clinical outcome is encouraging.","PeriodicalId":19224,"journal":{"name":"Nigerian Journal of Basic and Clinical Sciences","volume":"4 1","pages":"164 - 166"},"PeriodicalIF":0.1,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90066795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Massive maxillary peripheral giant cell granuloma in a 12-year-old male: Case report","authors":"George Ewansiha, Abdulrahman Goshi, I. Ibrahim, Abdulmanan Yahaya, B. Bamgbose, J. Asaumi","doi":"10.4103/njbcs.njbcs_18_21","DOIUrl":"https://doi.org/10.4103/njbcs.njbcs_18_21","url":null,"abstract":"Peripheral giant cell granuloma (PGCG) is a benign, hyperplastic reactive lesion arising from the mucoperiosteum of the alveolar ridge following chronic irritation or trauma. It is characterized by the presence of multinucleated giant cells. We report a 12-year-old male with massive maxillary PGCG where ultrasonography was used as the first line of investigation to determine the severity and vascularity of the lesion based on differential diagnosis. The ultrasonographic findings showed well-defined hyperechoic multifocal echogenic areas and low-resistant spectral waveforms obtained on Doppler were consistent with benign soft tissue lesions. The histopathological examination showed that of a typical multinucleated giant cell with the diagnosis of PGCG.","PeriodicalId":19224,"journal":{"name":"Nigerian Journal of Basic and Clinical Sciences","volume":"15 1","pages":"157 - 160"},"PeriodicalIF":0.1,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78980109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Papillary thyroid carcinoma presenting at entopic and ectopic sites: A diagnostic conundrum","authors":"Auwal Adamu, A. Ajiya, D. Suleiman, Yakubu Shirama","doi":"10.4103/njbcs.njbcs_75_21","DOIUrl":"https://doi.org/10.4103/njbcs.njbcs_75_21","url":null,"abstract":"Papillary thyroid carcinoma (PTC) mostly occurs within the thyroid gland (entopic site), with its occurrence within an ectopic thyroid tissue being rare comprising less than 1% of all thyroid cancers. The coexistence of PTC in entopic and ectopic sites is even rarer, and differentiating ectopic PTC from a metastatic cervical lymph node may pose a diagnostic conundrum. This report is aimed at highlighting the diagnostic challenges and treatment of this rare condition.","PeriodicalId":19224,"journal":{"name":"Nigerian Journal of Basic and Clinical Sciences","volume":"117 1","pages":"161 - 163"},"PeriodicalIF":0.1,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76172396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mortality review in a maxillofacial center in Northern Nigeria","authors":"B. Fomete, R. Agbara, Modupeola A. Samaila, T.O. Agho, E. Ikekhuamen","doi":"10.4103/njbcs.njbcs_14_22","DOIUrl":"https://doi.org/10.4103/njbcs.njbcs_14_22","url":null,"abstract":"Context: Mortality pattern is an essential component in health delivery globally. It is an important medical appraisal that should be made regularly. Mortality in maxillofacial patients often results from co-morbidity from others diseases as seen in Ludwig's angina and advanced stage malignancies. Aim: To document the causes of maxillofacial mortalities during a 12-year period. Materials and Methods: An analysis of all cases of death recorded in the Department of Oral and Maxillofacial Surgery of a Nigerian tertiary health Centre from January 2006 to December 2018. Results: A total of 3255 oral and maxillofacial patients were seen during 12-year period. About 65 deaths were recorded accounting for 2.0% of all cases of which 69.2% were males, whereas 30.8% females. The age group most affected was 30 to 39 with 23.1% closely followed by 20 to 29 with 21.5%. Conclusion: Cervicofacial infection was the commonest causes of mortality in oral and maxillofacial surgery in our environment.","PeriodicalId":19224,"journal":{"name":"Nigerian Journal of Basic and Clinical Sciences","volume":"16 1","pages":"93 - 95"},"PeriodicalIF":0.1,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82478406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of urea, creatinine levels, and proteinuria among obese individuals within abakaliki metropolis","authors":"Ugomma A. Ude, M. Kalu, Chinenye Ogbonna, V. Usanga, S. Azi","doi":"10.4103/njbcs.njbcs_74_21","DOIUrl":"https://doi.org/10.4103/njbcs.njbcs_74_21","url":null,"abstract":"Context: The deleterious effects of obesity on human health are systemic, and kidney dysfunction is now recognized as a health risk posed by obesity. Aim: The study was aimed at evaluating serum urea, creatinine levels, and proteinuria among obese individuals living in Abakaliki Metropolis. Settings and Design: This was a cross-sectional study of individuals living within Abakaliki Metropolis between August 2020 and September 2021. Materials and Methods: A total of 242 participants made up of 168 obese and 74 non-obese who consented to the study were recruited. Blood and urine samples were collected for the estimation of urea, creatinine levels, and proteinuria. Anthropometric data were collected using meter rule and digital scale for calculation of body mass index (BMI). Demographic data were collected using structured questionnaires. Systolic blood pressure (SBP) and diastolic blood pressure (DBP) were measured using a digital sphygmomanometer under standard conditions. Statistical Analysis: The data generated were analyzed using Statistical Package for Social Sciences, version 20.0 (SPSS Inc. Chicago Illinois). Results: The results showed a higher BMI, SBP, DBP, urea, and creatinine levels in those with obesity than the non-obese. Females with obesity had non-significantly higher levels of urea and creatinine than males with obesity (P > 0.05). BMI, age, and SBP were observed to positively correlate with urea and creatinine levels among the obese. Participants in class II obesity had the highest urea level (6.37 ± 4.65) compared to other groups. Conclusion: A good control of weight helps to forestall progressive renal impairment.","PeriodicalId":19224,"journal":{"name":"Nigerian Journal of Basic and Clinical Sciences","volume":"11 1","pages":"120 - 125"},"PeriodicalIF":0.1,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83395702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pattern and outcome of heart failure amongst children admitted in an emergency pediatric unit of a Tertiary Hospital in Sokoto State, North-Western Nigeria","authors":"K. Isezuo, U. Sani, U. Waziri, B. I. Garba, L. Coker, Abdulrasheed Folorunsho","doi":"10.4103/njbcs.njbcs_17_22","DOIUrl":"https://doi.org/10.4103/njbcs.njbcs_17_22","url":null,"abstract":"Context: Heart failure (HF) is a major cause of mortality in the emergency pediatric unit (EPU). It is the usual presentation of many structural cardiac and non cardiac diseases. An audit of the causes of heart failure is necessary to ensure adequate management and prevention. Aim: We describe the pattern and outcome of children with HF admitted to an EPU of a tertiary hospital in Sokoto. Materials and Methods: This was a cross-sectional study conducted in the EPU over 24 months (May 2019 to April 2021). Children aged 1 month to 15 years admitted with heart failure were recruited consecutively. The demographic characteristics, cause of heart failure, and outcome were entered into a proforma. Data were analyzed using IBM SPSS version 25. Results: One hundred and fifty-five out of 7158 children (2.2%) had HF. Majority of these 103 (66.5%) were aged 1 month to 5 years. The age range was 1–180 months with a mean of 55.4 (±53.7) months and a median of 36 (IQR: 86 months). Males accounted for 84 (54.2%) with a ratio of 1.18:1. The commonest causes of heart failure were congenital heart disease (CHD) 40: 25.8%; severe anemia 34: 21.9%; bronchopneumonia 30: 19.4%; rheumatic heart disease (RHD) 18: 11.6%; and dilated cardiomyopathy 16: 10.3%. There were 45(29.0%) deaths, of which CHD, RHD and severe anaemia accounted for the highest mortality. Conclusion: Structural heart diseases like CHD and RHD, in addition to severe anemia and bronchopneumonia, are significant causes of heart failure and mortality in this environment. A holistic approach to prevention is necessary to reduce the burden.","PeriodicalId":19224,"journal":{"name":"Nigerian Journal of Basic and Clinical Sciences","volume":"5 1","pages":"126 - 131"},"PeriodicalIF":0.1,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84265166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}