Nucleosides & nucleotides最新文献_第9页

A single carbocyclic nucleotide substitution in a 12mer DNA gives a Hoogsteen basepaired duplex (till 38 degrees C) and a hairpin (till 65 degrees C). A 600 MHz NMR spectroscopic study. 在一个12聚体DNA中，一个单碳环核苷酸取代得到一个胡格斯汀碱基双链(直到38摄氏度)和一个发夹(直到65摄氏度)。600 MHz核磁共振光谱研究。

Nucleosides & nucleotides Pub Date : 1999-06-01 DOI: 10.1080/07328319908044793

J Isaksson, T Maltseva, P Agback, X Luo, A Kumar, E Zamaratski, J Chattopadhyaya

引用次数: 2

Effect of oligomer length and base substitutions on the cytotoxic activity and specific nuclear protein recognition of GTn oligonucleotides in the human leukemic CCRF-CEM cell line. 低聚物长度和碱基取代对人白血病CCRF-CEM细胞系GTn寡核苷酸细胞毒活性和特异性核蛋白识别的影响

Nucleosides & nucleotides Pub Date : 1999-06-01 DOI: 10.1080/07328319908044830

C Morassutti, B Dapas, B Scaggiante, G Paroni, L Xodo, F Quadrifoglio

引用次数: 11

Modified nucleoside 5'-triphosphonates as a new type of antiviral agents. 修饰核苷5′-三膦酸盐作为一种新型抗病毒药物。

Nucleosides & nucleotides Pub Date : 1999-04-01 DOI: 10.1080/15257779908041639

E A Shirokova, A V Shipitsin, L S Victorova, N B Dyatkina, L E Goryunova, R S Beabealashvilli, C J Hamilton, S M Roberts, A A Krayevsky

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引用次数: 5

Synthesis and inhibitory activity against phosphatidylinositol 4-kinase of echiguanine analogs. 酯瓜氨酸类似物的合成及其对磷脂酰肌醇4-激酶的抑制活性。

Nucleosides & nucleotides Pub Date : 1999-04-01 DOI: 10.1080/15257779908041550

Y Saito, K Kato, K Umezawa

引用次数: 3

Synthesis and testing of new modified nucleosides. 新修饰核苷的合成与测试。

Nucleosides & nucleotides Pub Date : 1999-04-01 DOI: 10.1080/15257779908041490

M E Jung, C J Nichols, O Kretschik, Y Xu

引用次数: 11

Potent anti-hepatitis B viral activity and inhibition of bacteriophage T7 RNA polymerase by a "fat" nucleoside and its 5'-triphosphate derivative: synthetic, biochemical, and biological studies of 4,8-diamino-6-imino-6H-1-beta-D-ribofuranosyl-imidazo[4,5-E] [1,3]diazepine-5'-triphosphate. 一种“脂肪”核苷及其5′-三磷酸衍生物对噬菌体T7 RNA聚合酶的有效抗乙型肝炎病毒活性和抑制作用:4,8-二氨基-6-亚胺- 6h -1- β -d -核呋喃基-咪唑[4,5- e][1,3]二氮平-5′-三磷酸的合成、生化和生物学研究

Nucleosides & nucleotides Pub Date : 1999-04-01 DOI: 10.1080/15257779908041574

M Bretner, D Beckett, R S Hosmane

引用次数: 3

Resistance profiles of (+)2'-deoxy-3'-oxa-4'-thiocytidine and (-)2'-deoxy-3'-oxa-4'-thio-5-fluorocytidine. (+)2'-脱氧-3'-氧-4'-硫代胞苷和(-)2'-脱氧-3'-氧-4'-硫-5-氟代胞苷的抗性谱。

Nucleosides & nucleotides Pub Date : 1999-04-01 DOI: 10.1080/15257779908041564

N Richard, H Salomon, M Oliveira, R Rando, M A Wainberg

引用次数: 1

Structural determinants of HIV-1 reverse transcriptase stereoselectivity towards (beta)-L-deoxy- and dideoxy-pyrimidine nucleoside triphosphates: molecular basis for the combination of L-dideoxynucleoside analogs with non-nucleoside inhibitors in anti HIV chemotherapy. HIV-1逆转录酶对(β)- l -脱氧和二脱氧嘧啶核苷三磷酸立体选择性的结构决定因素:l -二脱氧核苷类似物与非核苷抑制剂联合抗HIV化疗的分子基础

Nucleosides & nucleotides Pub Date : 1999-04-01 DOI: 10.1080/15257779908041566

G Maga, M Amacker, U Hübscher, G Gosselin, J L Imbach, C Mathé, A Faraj, J P Sommadossi, S Spadari

引用次数: 3

Stereospecific synthesis and antiviral activities of beta-L-2',3'-dideoxy-5-chloropyrimidine nucleoside derivatives. β - l -2′，3′-二脱氧-5-氯嘧啶核苷衍生物的立体特异性合成及其抗病毒活性。

Nucleosides & nucleotides Pub Date : 1999-04-01 DOI: 10.1080/15257779908041526

C Pierra, G Gosselin, J P Sommadossi, A Faraj, E De Clercq, J Balzarini, J L Imbach

引用次数: 1

Hydrolysis of some mRNA 5'-cap analogs catalyzed by the human Fhit protein--and lupin ApppA hydrolases. 由人类Fhit蛋白和lupin ApppA水解酶催化的一些mRNA 5'-cap类似物的水解。

Nucleosides & nucleotides Pub Date : 1999-04-01 DOI: 10.1080/15257779908041666

E Bojarska, R Kraciuk, J Wierzchowski, Z Wieczorek, J Stepiński, M Jankowska, E Starzyńska, A Guranowski, E Darzynkiewicz

引用次数: 3